The invention discloses whitening and freckle removal cream and a preparation method of the whitening and freckle removal cream. The whitening and freckle removal cream comprises the following raw materials in parts by mass: 2-7.5 parts of emolsifier, 5-7.5 parts of isononyl isononanoate, 8-10 parts of polyethylene glycol, 4.5-9.5 parts of silicone oil, 2-4 parts of jojoba oil, 2.5-5 parts of squalane, 0.15-0.2 parts of preservative, 0.1-0.2 parts of antioxidant, 0.3-0.8 parts of antioxidation assistant, 0.15-0.3 parts of allantoin, 3-5 parts of glycerol, 0.02-0.08 parts of sodium hyaluronate,1-3 parts of skin humectant, 1-2 parts of stabilizer, 3-5 parts of skin whitening agent, 5-9 parts of 1,3-butanediol, 0.3-0.6 parts of plant anti-allergy agent and 0.05 parts of odorant. The whitening and freckle removal cream employs plant whitening ingredients, is safe and effective, can inhibit exertion of a melanin formation chain, effectively removes freckles, whitens skin and brightens a skin color.