The invention discloses a method for breeding and increasing the yield of white mullets, which comprises the following steps of: S1, selecting breeding fish for the first time; S2, selecting the breeding fish for the second time; S3, after selecting parent fish for the first time, putting the parent fish into a sterile parent fish pond for independent feeding; S4, culturing second parent fish on the basis of selecting good parent fish for the second time; S5, selecting the parent fish during spawning of the white mullets, and selecting the parent fish with large mature body sizes; S6, carryingout spawning induction medicine injection on female fish for two times, and carrying out one-time injection on male fish; S7, placing the spawned parent fish in a greenhouse for spawning and hatching; S8, two days after the fish fries are ovulated, transferring the fish fries to a water flower fish pond for culture; S9, adding fresh water, adding photosynthetic bacteria and phosphate fertilizer,and feeding zooplankton; S10, feeding minced fish meat, finishing fish fry cultivation, and separating the fish fries to different ponds for adult fish cultivation. According to the invention, a secondary injection spawning induction method is used, so that the eggs of the female fish are more mature, and the hatching rate is high; the eggs are protected by the parent fish for hatching, and the survival rate is improved.