Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
35results about How to "Mild structure" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Low molecular hyaluronate, preparation method and purpose thereof
ActiveCN103255187ALow costHigh purityOrganic active ingredientsCosmetic preparationsAntioxidant capacityHyaluronidase
The invention belongs to the fields of enzymology and pharmaceutical chemistry, and relates to the low molecular hyaluronate, preparation method and purpose thereof. Concretely, the preparation method comprises a degradation step of hyaluronic acid or salt thereof whose molecular weight is greater than 1000 kDa by hyaluronidase prepared by Bacillus spp whose preservation number is CGMCC No. 5744 or SEQ ID No:2 coded hyaluronidase. The preparation of low molecular hyaluronic acid or salts thereof by using hyaluronidase produced by Bacillus spp of the present invention has the advantages of simple operation, mild condition, non-destroy of the product structure and low cost. The product is suitable for large scale industrialized production. The low molecular hyaluronate prepared by the invention has the advantages of good transdermal absorbency, good purity, non-cytotoxicity, good antioxidation, etc., and can be used in the fields of cosmetic, foodstuff and medicine.
Owner:BLOOMAGE BIOTECHNOLOGY CORP LTD
Preparation method and application of nitrogen-doped porous carbon material
ActiveCN108128765ASolve uncontrollable key problemsRealize high-value utilizationHybrid capacitor electrodesCarbon preparation/purificationPorous carbonProton
The invention discloses a preparation method and an application of a nitrogen-doped porous carbon material. A series of alginic acid proton ionic liquids are prepared based on the presence of a carboxyl group in the molecular structure of alginic acid by using a reaction of the carboxyl group and organic bases having different structures, the reaction is mild, the structures of the alginic acid proton ionic liquids can be easily and conveniently adjusted by regulating the structures of the organic bases in order to achieve the purpose of regulating the content and the kind of nitrogen in the nitrogen-doped porous carbon material and a precursor thereof, the alginic acid is doped with nitrogen in situ at the molecular level to solve the key problem of uncontrollability of a carbon source and a nitrogen source in order to realize the high-value utilization of a nitrogen-containing carbon material, and the alginic acid-based nitrogen-containing carbon material can be successful individually used as an electrode material, and can be successfully applied to the field of energy storage.
Owner:GUIZHOU UNIV
Vacuum belt type drying units
InactiveCN101368788AStable and reliable drying qualityQuality improvementDrying machinesCooling temperatureHuman–machine interface
The invention provides a unit which can continuously coat the viscous liquid material on a conveyor belt and achieve low-temperature drying in a vacuum state. The unit comprises a vacuum cavity body; a material conveying belt delivery mechanism is arranged in the vacuum cavity body which is connected with an adjustable vacuum system; a feeding mechanism and a distributing mechanism are arranged at the front end of the unit; and a cutting mechanism, a powder shoveling mechanism, a crushing mechanism and a material collector are arranged in sequence at the rear end of the unit. The entire unit can adopt a DCS distributed control system and a touch-screen human-machine interface operating system to effectively control the complex relationships among the heating temperature, the vacuum degree, the cooling temperature, the delivery speed of the unit and the dried extract powder quality, so that the drying quality of batch products can be more stable and reliable.
Owner:温州市金榜轻工机械有限公司
Polycarbonate polyurethane and green preparation method thereof
The invention relates to polycarbonate polyurethane and a green preparation method thereof. The polycarbonate polyurethane comprises polyurethane structural units and aliphatic polycarbonate structural units which are irregularly distributed. The polycarbonate polyurethane is successfully prepared by a nonisocyanate method, so that isocyanate and solvents are not used, and the development requirements of green chemical industry are met. In addition, the green preparation method of the polycarbonate polyurethane is relatively mild in reaction condition and low in requirement on devices; by selecting raw materials with different structures, the polycarbonate polyurethane having different linear structures and comprising two irregularly distributed structural units can be prepared, so that the structures are diverse and controllable; the prepared polycarbonate polyurethane is free of residue of isocyanate monomers, so that the application of polycarbonate polyurethane to the fields of foods and medicines is broadened.
Owner:INST OF CHEM CHINESE ACAD OF SCI
Medical sealing glue capable of promoting wound healing and preparation method thereof
ActiveCN109568641AImprove mechanical propertiesStrong mechanical propertiesSurgical adhesivesPharmaceutical delivery mechanismWound healingMedicine
The invention discloses in-situ crosslinking shaping medical sealing glue capable of promoting wound healing and a preparation method thereof. The medical sealing glue has the gelling time being 1 to10s, the swelling degree being 0 to 100 percent, the cracking intensity being 100 to 250mmHg and the degradation time being 0.5 to 300 days. The medical sealing glue is prepared from two ingredients through being physically mixed by a mixing tool and then being subjected to covalent cross-linking; a first ingredient is a nucleophilic ingredient; a second ingredient is an electrophilic ingredient.The medical nucleophilic ingredient contains exosomes or hyaluronic acid and chitosan, so that the medical sealing glue has the effect of promoting the wound healing; the antibacterial and anti-infection effects are achieved.
Owner:SHANDONG BRANDEN MEDICAL DEVICE
O-unsaturated fatty acid acylated chitosan oligosaccharides as well as preparation and application thereof
ActiveCN102532345AHigh selectivityClear structureEsterified saccharide compoundsSugar derivativesBlood sugarCHITOSAN OLIGOSACCHARIDE
The invention relates to O-unsaturated fatty acid acylated chitosan oligosaccharides, which are characterized in that the O-unsaturated fatty acid acylated chitosan oligosaccharides are a mixed component and have a molecular weight of 800-25000 Da; the deacelation degree of the mixed component is 50-100%; the substitution degree of O-unsaturated fatty acid is 30-200%; and the components of the O-unsaturated fatty acid acylated chitosan oligosaccharides have a structure shown in the specification, wherein R1 is H or CH3CO-, R2 is C12-22 unsaturated fatty acid acyl or H, and n is 0-30. The O-unsaturated fatty acid acylated chitosan oligosaccharides have activities of resisting oxidation, delaying aging, inhibiting tumor, resisting inflammation, lowering blood pressure, preventing thrombosis, improving diabetes mellitus, lowering blood sugar, resisting atherosclerosis and the like, and can be used as important raw materials for medicines, health-care food and cosmetics.
Owner:DALIAN GLYCOBIO
Process for preparing nano-sized peanut protein powder
InactiveCN101015319ASmall granularityFunctionalProteins working-up by texturisingVegetable proteins working-upUltra high pressureHigh pressure homogenization
The invention relates to a method for preparing nanometer peanut protein powder. It takes condensed peanut protein powder (defatted protein powder) as raw material, employs dynamic ultra-pressure homogenizing to replace traditional dry processing treatment, and prepares final product through spray drying. The invention is characterized in that: (1) it modifies condensed peanut protein powder (separated powder) by using physical modification to loose structure of peanut protein, which is favorable for subsequent process; the treating condition is temperate and the water retention and other function of condensed peanut protein can be maintained; (2) it removes unpleasant odor and makes it more acceptable; (3) the treatment of dynamic ultra-pressure homogenizing makes the granule be smaller than 200 nm, and the taste is much better; (4) the process is simple and easier for industrialization.
Owner:NANCHANG UNIV
Carbon nano tube complex gene vector system and preparation method thereof
InactiveCN103877580ADoes not damage the structureMild structureGenetic material ingredientsInorganic non-active ingredientsCholesterolCarbon nanotube
The invention discloses a carbon nano tube complex gene vector system, and researches the effectiveness, biocompatibility, cytotoxicity, transfection efficiency and the like of the carbon nano tube complex gene vector system. Polyethyleneimine-cholesterol (PEI-Chol) and polyethylene glycol-distearoyl phosphatidyl ethanolamine (DSPE-PEG) are combined on the wall of the carbon nano tube through hydrophobic interaction, so as to obtain the carbon nano tube complex gene vector system. The preparation method comprises specific steps of (1) synthesizing polyethyleneimine-cholesterol by using polyethyleneimine and cholesteryl chloroformate through a dehydrating agent triethylamine under anhydrous low temperature condition; (2) obtaining the water-soluble positive ion carbon nano tube complex system by using polyethyleneimine-cholesterol and polyethylene glycol-distearoyl phosphatidyl ethanolamine through ultrasonic dispersion. The carbon nano tube complex system can be steadily and uniformly dispersed in phosphate solution (pH=7.4), cell medium and serum in 24 hours, has low toxicity, effectively combines and concentrates DNA molecules, and has high transfection efficiency.
Owner:ZHEJIANG UNIV
Protein polypeptide drug long-acting microspheres and preparation method thereof
ActiveCN108403643AEasy to prepareMild preparation methodPeptide/protein ingredientsPharmaceutical non-active ingredientsDrugs solutionPeristaltic pump
The invention relates to protein polypeptide drug long-acting microspheres and a preparation method thereof. The preparation method comprises the steps of (1) dissolving a protein or polypeptide water-soluble drug and a protein protectant to obtain an aqueous drug solution; dissolving a macromolecular carrier material in an organic solvent to obtain an oil phase macromolecular solution; (2) addingthe aqueous drug solution into the oil phase macromolecular solution, and using a cell disrupter or a high-speed shear apparatus to prepare W / O emulsion; (3) feeding the W / O emulsion into a superfineparticle preparation system through a peristaltic pump so as to obtain the protein polypeptide drug long-acting microspheres. The protein polypeptide drug long-acting microspheres prepared via the preparation method have the advantages of good preparation process simplicity, controllable parameters, good reproducibility, and high production efficiency. The protein polypeptide drug long-acting microspheres prepared herein have the advantages of high drug encapsulating rate, low sudden release agent, stable and lasting release speed of drug, smooth microsphere surface, good spherical shape integrity, and homogenous particle size.
Owner:SUN YAT SEN UNIV
Method for extracting coronatine from fermentation liquor by using membrane separation technique
InactiveCN101665448AOvercome the defects of low yield and large sewage dischargeOvercome the disadvantage of large emissionsUltrafiltrationCarboxylic acid amide separation/purificationFiltration membraneSeparation technology
The invention discloses a method for extracting coronatine from fermentation liquor by using a membrane separation technique, comprising micro-filtration and hyper-filtration steps: filtering a fermentation liquor containing coronatine by a micro filtering membrane with the aperture of 0.1-10 Mum so as to remove impurity particles and thalli; then filtering the liquor by a hyper-filtration membrane with the aperture of 0.001-0.1 Mum so as to remove macromolecule impurities of proteins, nucleic acids and colloid granules to obtain clear filtrate; and then carrying out common resin exchange or column chromatography, concentrating and crystallizing to obtain the coronatine. In order to improve the effect of separating purification, pre-treatment can be added before the micro-filtration, namely, the coronatine fermentation liquor is filtered though the filtration membrane with the aperture of 1-10 Mum; nano-filtration can be added after the hyper-filtration, namely, the effluence liquor isfiltered by a nano-membrane system with cut-off molecular weight of 400-800. The method in the invention has simple operation and high yield which can be over 90%; in addition, the method has no influence on the structure and activity of the coronatine; and has low energy consumption and low pollution, thus completely satisfying the requirements of industrialized production.
Owner:JIANGXI AGRICULTURAL UNIVERSITY
Remediation tank for heavy metal contaminated soil
The invention discloses a remediation tank for heavy metal contaminated soil. The remediation tank comprises a tank body, the bottom of the tank body is obliquely arranged, the inclination angle is 5-10 DEG, a waterproof layer is laid on the bottom of the tank body, the inclined lower end of the tank body communicates with a water discharge pipe, the water discharge tube is provided with a water discharge valve, and a soil turning device is arranged in the tank body. The remediation tank can conveniently remediate soil, can turn the soil easily by arranging the soil turning device, and avoidsanother soil turning devices from being manually operated for soil turning remediation; and a method for remediating soil by adopting a chemical leaching agent makes the contaminated soil transferredinto the remediation tank and remediated, so the chemical leaching agent is prevented from being added to affect other soils.
Owner:耿言华
Ferrocenyl pyrimidine pincer ligand and preparation method thereof
InactiveCN103242378AImprove thermal stabilityImprove the coordination effectOrganic compound preparationOrganic-compounds/hydrides/coordination-complexes catalystsArylOrtho position
The invention discloses a ferrocenyl pyrimidine pincer ligand and a preparation method thereof and belongs to the technical field of organic synthesis. The ferrocenyl pyrimidine pincer ligand has the general formula shown in the specification, wherein X and Y are atom C or N; R1 and R2 are C1-C6 linear alkyl, -C6H5, -COCH3, -COOCH3, -CHO, -OCH3, -N(CH3)2, -CN or -COOH; R1 is connected to the ortho-position, meta-position or para-position of X; and R2 is connected to ortho-position, meta-position or para-position of Y. According to the corresponding preparation method, 2,4,6-trichloro pyrimidine, ferrocene mercuric chloride, aryl or heterocyclic aryl boric acid serve as raw materials, and the ferrocenyl pyrimidine pincer ligand of a rich structure is prepared through a stepped coupling method. The preparation method is mild in reaction conditions, wide in substrate range and high in yield. The selected raw material ferrocene mercuric chloride has high stability and high stereoselectivity in air and water, the compound can be prepared by directly mercurating ferrocene, and the operation is easy and readily available. Meanwhile, multiple asymmetric pincer structures can be conveniently obtained by utilizing the preparation method, and the ligand has wide application prospect.
Owner:LUOYANG NORMAL UNIV
Method for extracting coronatine from fermentation liquor by using membrane separation technique
InactiveCN101665448BOvercome the disadvantage of large emissionsSimple processUltrafiltrationCarboxylic acid amide separation/purificationFiltration membraneSeparation technology
The invention discloses a method for extracting coronatine from fermentation liquor by using a membrane separation technique, comprising micro-filtration and hyper-filtration steps: filtering a fermentation liquor containing coronatine by a micro filtering membrane with the aperture of 0.1-10 Mum so as to remove impurity particles and thalli; then filtering the liquor by a hyper-filtration membrane with the aperture of 0.001-0.1 Mum so as to remove macromolecule impurities of proteins, nucleic acids and colloid granules to obtain clear filtrate; and then carrying out common resin exchange or column chromatography, concentrating and crystallizing to obtain the coronatine. In order to improve the effect of separating purification, pre-treatment can be added before the micro-filtration, namely, the coronatine fermentation liquor is filtered though the filtration membrane with the aperture of 1-10 Mum; nano-filtration can be added after the hyper-filtration, namely, the effluence liquor is filtered by a nano-membrane system with cut-off molecular weight of 400-800. The method in the invention has simple operation and high yield which can be over 90%; in addition, the method has no influence on the structure and activity of the coronatine; and has low energy consumption and low pollution, thus completely satisfying the requirements of industrialized production.
Owner:JIANGXI AGRICULTURAL UNIVERSITY
Harengula zunasi glycoprotein extracting method and application
The invention relates to the technical field of biochemistry, and discloses a harengula zunasi glycoprotein extracting method and application. The extracting method comprises steps of pretreatment, ultrasonic treatment plus hot water extraction, concentrated alcohol precipitation, washing and purification, dialysis and freeze drying and the like. Through a single factor experiment and an orthogonal experiment method, the harengula zunasi glycoprotein extracting process is comparatively optimized, and the best harengula zunasi glycoprotein extracting process parameters are obtained. The harengula zunasi glycoprotein extracting method disclosed in the invention has the advantages that the design is reasonable, the process is simple, the product extraction rate is high, the use of a large amount of a toxic solvent is not needed, the product safety is good, the preparation cost is low, promotion and application are easy and the like. A cell experiment verifies and shows that the harengulazunasi glycoprotein plays a significant role in regulation of cellular immunity, which provides a reference for application of the harengula zunasi glycoprotein to the development of pharmaceuticals and foods.
Owner:SOUTH CHINA AGRI UNIV
Ferrocenyl pyrimidine pincer ligand and preparation method thereof
InactiveCN103242378BImprove thermal stabilityImprove the coordination effectOrganic compound preparationOrganic-compounds/hydrides/coordination-complexes catalystsOrganic synthesisOrtho position
The invention discloses a ferrocenyl pyrimidine pincer ligand and a preparation method thereof and belongs to the technical field of organic synthesis. The ferrocenyl pyrimidine pincer ligand has the general formula shown in the specification, wherein X and Y are atom C or N; R1 and R2 are C1-C6 linear alkyl, -C6H5, -COCH3, -COOCH3, -CHO, -OCH3, -N(CH3)2, -CN or -COOH; R1 is connected to the ortho-position, meta-position or para-position of X; and R2 is connected to ortho-position, meta-position or para-position of Y. According to the corresponding preparation method, 2,4,6-trichloro pyrimidine, ferrocene mercuric chloride, aryl or heterocyclic aryl boric acid serve as raw materials, and the ferrocenyl pyrimidine pincer ligand of a rich structure is prepared through a stepped coupling method. The preparation method is mild in reaction conditions, wide in substrate range and high in yield. The selected raw material ferrocene mercuric chloride has high stability and high stereoselectivity in air and water, the compound can be prepared by directly mercurating ferrocene, and the operation is easy and readily available. Meanwhile, multiple asymmetric pincer structures can be conveniently obtained by utilizing the preparation method, and the ligand has wide application prospect.
Owner:LUOYANG NORMAL UNIV
A kind of production method of conjugated linoleic acid
ActiveCN109134237BReduce pollutionHigh utilization rate of raw materialsOrganic compound preparationCarboxylic compound separation/purificationChemical synthesisTrans esterification
The invention discloses a production method of conjugated linoleic acid, which belongs to the field of chemical synthesis methods of fats and oils. The separated short alcohol ester of linoleic acid is subjected to alkali-catalyzed isomerization, saponification, acid hydrolysis and water washing to obtain conjugated linoleic acid. The production process of the present invention can be carried out continuously and efficiently, and has the advantages of simple preparation process, mild reaction conditions, high utilization rate of raw materials, high product purity, and high product stability; low energy consumption not only reduces production cost, but also reduces Pollution to the environment, suitable for large-scale production.
Owner:HANDAN CHENGUANG PRECIOUS OIL
A method for improving the performance of infrared and terahertz chips and infrared and terahertz chips
ActiveCN111900231BImprove performancePerformance does not breakMaterial nanotechnologyFinal product manufactureReduction treatmentPhysical chemistry
The invention provides a method for improving the performance of infrared and terahertz chips and the infrared and terahertz chips. The method for improving the performance of infrared and terahertz chips includes the following steps: providing a core-shell silver nanoparticle; disposing the core-shell silver nanoparticle on the infrared and terahertz chip; wherein, the core-shell silver nanoparticle In a reaction medium with a boiling point of 100-170°C, in the presence of a protective agent, the precursor of the core structure is reduced at least once at a temperature of 100-170°C to obtain nano-seed particles of the core structure; and at 25-100°C At a reaction temperature of ℃, it is obtained by adding a shell-structured precursor and performing at least one reduction treatment. The infrared and terahertz chip obtained based on the manufacturing method of the invention has high modulation depth, response speed and wide working bandwidth, thereby ensuring ideal performance of the terahertz system.
Owner:HEFEI UNIV OF TECH
Method for preparing resveratrol
ActiveCN108840788ALow priceHigh yieldOrganic compound preparationCarboxylic acid esters preparationMedicinal chemistryPollution
The invention relates to a method for preparing resveratrol. 4-hydroxycinnamic acid serves as an initial raw material. High yield can be obtained, pollution is slight, and reaction conditions are mild. The method is a novel method for well synthesizing resveratrol.
Owner:YANGZHOU UNIV
A kind of extraction method and application of medlar glycoprotein
ActiveCN110196333BPromote dissolutionHigh extraction rateBiological testingBiotechnologyFreeze-drying
Owner:SOUTH CHINA AGRI UNIV
Preparation method of multi-slit nanofiber aggregate yarn
The invention discloses a preparation method of a multi-slit nanofiber assembly yarn, which comprises the following steps: (1) cutting the iridescent film into a continuous non-dyed multicolored flat yarn with a film slitting machine; (2) making the step ( 1) The obtained continuous non-dyed multicolored flat yarns are divided into groups of 1-10 pieces, sprayed with air through the fluid nozzle for twisting, while spraying air for twisting, heat the twisting point with a heating device to make the continuous non-dyed multicolored flat yarns The silk is softened, then wound and stretched by a winding device to obtain a five-color yarn; (3) the five-color yarn obtained in step (2) is output to the winding device to make a twisted five-color yarn bobbin. The preparation method of the invention has simple operation, mild conditions, and low cost of raw materials. The winding and stretching of the invention increases the thinning of the flat filaments, improves the mutual cohesion fastness, and improves the overall strength of the multi-slit nanofiber assembly yarn.
Owner:ZHONGYUAN ENGINEERING COLLEGE
A kind of preparation method of resveratrol
ActiveCN108840788BLow priceHigh yieldOrganic compound preparationCarboxylic acid esters preparationEngineeringOrganic chemistry
Owner:YANGZHOU UNIV
A kind of electrochemical sensor based on graphene molecularly imprinted material and preparation method thereof
ActiveCN104374815BImprove conductivityLarge specific surface areaMaterial electrochemical variablesDispersityNon-covalent interactions
The present invention provides an electrochemical sensor based on a graphene molecular imprinting material, and a preparation method thereof, and relates to the technical field of polymer material science and chemistry sensor combination. According to the present invention, graphene and a vinyl aromatic compound form vinyl functionalized graphene through the non-covalent interaction, free radical copolymerization is performed to prepare a graphene molecular imprinting polymer (GR / MIPs), and the GR / MIPs modified electrode, a reference electrode and a counter electrode are connected on an electrochemical workstation to form the electrochemical sensor of the graphene molecular imprinting material; the graphene and the vinyl aromatic compound are only required to be mixed according to the ratio so as to obtain the vinyl functionalized graphene through the non-covalent interaction, such that the operation is simple, the conditions are mild, the structure of graphene is not destroyed, and the graphene dispersity is improved; and the electrochemical sensor based on the graphene molecular imprinting material has advantages of rapid response, good selectivity, high sensitivity, good stability and the like.
Owner:湖州度信科技有限公司
Macrocyclic lactam compound containing rigid biaryl skeleton, and preparation method thereof
InactiveCN107540692AQuick and easy screeningImprove biological activityOrganic chemistryArylCarbon–nitrogen bond
The invention relates to a macrocyclic lactam compound containing a rigid biaryl skeleton and a preparation method thereof, and mainly solves the technical problem that currently there are few macrocyclic lactam compounds containing a rigid biaryl skeleton linked by carbon-nitrogen bonds. The technical scheme of the present invention: the macrocyclic lactam compound containing rigid biaryl skeleton is characterized in that it has the following general structural formula: R1 and R2 are alkyl, cycloalkyl, aryl or alkyl are connected with heteroatom and aromatic One of the substituents of the group.
Owner:上海药明康德新药开发有限公司
A kind of polycarbonate polyurethane and its green preparation method
The invention relates to polycarbonate polyurethane and a green preparation method thereof. The polycarbonate polyurethane comprises polyurethane structural units and aliphatic polycarbonate structural units which are irregularly distributed. The polycarbonate polyurethane is successfully prepared by a nonisocyanate method, so that isocyanate and solvents are not used, and the development requirements of green chemical industry are met. In addition, the green preparation method of the polycarbonate polyurethane is relatively mild in reaction condition and low in requirement on devices; by selecting raw materials with different structures, the polycarbonate polyurethane having different linear structures and comprising two irregularly distributed structural units can be prepared, so that the structures are diverse and controllable; the prepared polycarbonate polyurethane is free of residue of isocyanate monomers, so that the application of polycarbonate polyurethane to the fields of foods and medicines is broadened.
Owner:INST OF CHEM CHINESE ACAD OF SCI
Protein polypeptide drug long-acting microspheres and preparation method thereof
ActiveCN108403643BEasy to prepareMild preparation methodPeptide/protein ingredientsPharmaceutical non-active ingredientsMicrosphereWater soluble drug
The invention relates to protein polypeptide drug long-acting microspheres and a preparation method thereof. The preparation method comprises the steps of (1) dissolving a protein or polypeptide water-soluble drug and a protein protectant to obtain an aqueous drug solution; dissolving a macromolecular carrier material in an organic solvent to obtain an oil phase macromolecular solution; (2) addingthe aqueous drug solution into the oil phase macromolecular solution, and using a cell disrupter or a high-speed shear apparatus to prepare W / O emulsion; (3) feeding the W / O emulsion into a superfineparticle preparation system through a peristaltic pump so as to obtain the protein polypeptide drug long-acting microspheres. The protein polypeptide drug long-acting microspheres prepared via the preparation method have the advantages of good preparation process simplicity, controllable parameters, good reproducibility, and high production efficiency. The protein polypeptide drug long-acting microspheres prepared herein have the advantages of high drug encapsulating rate, low sudden release agent, stable and lasting release speed of drug, smooth microsphere surface, good spherical shape integrity, and homogenous particle size.
Owner:SUN YAT SEN UNIV
Method and application of preparing nitrogen-doped porous carbon material
ActiveCN108128765BSolve uncontrollable key problemsRealize high-value utilizationHybrid capacitor electrodesCarbon preparation/purificationOrganic basePorous carbon
The invention discloses a method and application for preparing a nitrogen-doped porous carbon material. Based on the presence of carboxyl groups in the molecular structure of alginic acid, the present invention uses carboxyl groups to react with organic bases of different structures to prepare a series of alginic acid proton-type ionic liquids. The reaction is mild, and the algae can be adjusted simply and conveniently through the structure regulation of organic bases. The structure of the acid-protic ionic liquid achieves the purpose of regulating the nitrogen content and nitrogen type in the nitrogen-doped porous carbon material and its precursor. The in-situ nitrogen doping of alginic acid is carried out from the molecular level, which solves the problem of incompatibility between carbon and nitrogen sources. The key issue of control, and then realized the high-value utilization of nitrogen-containing carbon materials, successfully used alginic acid-based nitrogen-containing carbon materials as electrode materials alone, and successfully applied to the field of energy storage.
Owner:GUIZHOU UNIV
Catalyst for low-temperature gaseous phase synthesis of benzaldehyde and preparation method thereof
InactiveCN102139224BHigh purityEasy to recycleMolecular sieve catalystsOrganic compound preparationAlkaline earth metalPtru catalyst
The invention discloses a catalyst for low-temperature gaseous phase synthesis of benzaldehyde and a preparation method thereof. The molecular formula of the catalyst is M-Ag-HMS, wherein M is alkali metal, alkaline earth metal or rare earth metal element. The preparation method comprises the following steps of: dissolving primary amine RN serving as a template agent into absolute ethanol to obtain primary amine ethanol solution; preparing mixed solution of silver and potassium nitrate, adding the mixed solution into the primary amine ethanol solution, stirring the solution uniformly till a colloidal material is produced, dripping ethyl orthosilicate into the colloidal material with violent stirring, continuously stirring the colloidal material till sediment is generated, and performing crystallization, filtration, washing, drying, roasting, tabletting and screening to obtain the catalyst. The catalyst has the advantages of high catalytic activity, strong selectivity, simple synthesisprocess, stable structure and long life; when the catalyst is filled in a fixed bed reaction kettle to synthesize benzaldehyde by gaseous phase catalytic oxidation of benzyl alcohol, the reaction conditions are mild, the purity of the product is high, and the costs of separation and purification are reduced; and the catalyst is easy for reclamation and regeneration.
Owner:QIQIHAR UNIVERSITY
A kind of preparation method and application of pseudo sea dragon glycoprotein
ActiveCN110105426BStable structureImprove solubilityPeptide preparation methodsImmunological disordersBiotechnologyGlycoprotein
The invention relates to the technical field of biochemistry, and discloses a preparation method and application of a pseudo-hyron glycoprotein. The preparation method comprises the steps of pretreatment, degreasing treatment, hot water extraction, concentrated alcohol precipitation, washing and purification, dialysis freeze-drying and the like. By comparing and optimizing the extraction process of pseudo-hyronoprotein through single-factor experiment combined with orthogonal experiment method, the optimal preparation process parameters of pseudo-hyronoprotein are obtained. , convenient operation, high product extraction rate, high purity, low preparation cost, easy popularization and application, etc. The present invention also proves that the pseudo-hyron glycoprotein has a significant effect on the immunomodulatory activity through cell experiments The application of immune regulation and the maximal development and utilization of pseudo-sea dragons provide theoretical basis and reference value.
Owner:SOUTH CHINA AGRI UNIV
Method for extracting low-molecular-weight lignin from walnut shells through graded sedimentation of alkaline tetrahydrofurfuryl alcohol
The invention relates to a method for extracting low-molecular-weight lignin from walnut shells by graded sedimentation through alkaline tetrahydrofurfuryl alcohol. The method comprises the following steps: 1) crushing, sieving, washing and drying the walnut shells to obtain walnut shell powder, adding alkaline tetrahydrofurfuryl alcohol according to a certain solid-to-liquid ratio, conducting pre-treating at a certain temperature for a period of time to obtain mixed slurry, and performing reduced-pressure suction filtration on the mixed slurry to obtain a filtrate; 2) adding water into the filtrate, adjusting a pH value to 6, then carrying out primary centrifugation, and drying a precipitate to obtain a lignin fraction I; 3) adjusting the pH value of supernatant obtained after centrifugation to 4, then carrying out secondary centrifugation, and conducting drying to obtain a lignin fraction II; and 4) adjusting the pH value of a supernatant obtained after centrifugation to 2, then carrying out tertiary centrifugation, and performing drying to obtain a lignin fraction III. According to the method, the lignin is efficiently extracted from the walnut shells by using the alkaline tetrahydrofurfuryl alcohol, and then fractionation is performed through an acid precipitation method, so the lignin which is low in molecular weight, uniform in distribution and high in reaction activity is finally obtained.
Owner:ANHUI UNIVERSITY OF TECHNOLOGY
Preparing method and application of syngnathoides-biaculeatus glycoprotein
ActiveCN110105426AStable structureImprove solubilityPeptide preparation methodsImmunological disordersAlcoholFreeze-drying
The invention relates to the technical field of biochemistry, and discloses a preparing method and application of syngnathoides-biaculeatus glycoprotein. The preparing method includes the steps of pretreatment, ungrease treatment, hot water extraction, concentration alcohol precipitation, washing purification, dialysis freezing drying and the like; the extraction technology of the syngnathoides-biaculeatus glycoprotein is compared and optimized through single factor experiments combined with an orthogonal experiment method, and best preparing technology parameters of the syngnathoides-biaculeatus glycoprotein are obtained. The preparing method of the syngnathoides-biaculeatus glycoprotein has the advantages of being reasonable in design, simple in technology, convenient to operate, high inproduct extraction rate and purity, low in preparing cost, easy to apply and popularize and the like; it also verifies and explains that the syngnathoides-biaculeatus glycoprotein has a remarkable effect in the aspect of the immune adjustment activity through cell experiments, and the theoretical basis and the reference value are provided for application of the syngnathoides-biaculeatus glycoprotein in the immune adjustment aspect and maximum development and utilization of syngnathoides biaculeatus.
Owner:SOUTH CHINA AGRI UNIV
Features
- R&D
- Intellectual Property
- Life Sciences
- Materials
- Tech Scout
Why Patsnap Eureka
- Unparalleled Data Quality
- Higher Quality Content
- 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com