51 results about "Carbon–nitrogen bond" patented technology

Disclosed are compounds produced by a process comprising the step of reacting an amine reactant with an epoxide reactant to form a hydrolytically stable carbon-nitrogen bond therebetween, wherein at least one of the amine or epoxide reactants comprises a terminal alkoxysiyl group. Also disclosed are curable compositions comprising the compounds of the present invention and the cured products derived therefrom.

One aspect of the present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-sulfur bond between the sulfur atom of a thiol moiety and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In other embodiments, the present invention relates to copper(II)-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of an amide and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-carbon bond between the carbon atom of cyanide ion and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In another embodiment, the present invention relates to a copper-catalyzed method of transforming an aryl, heteroaryl, or vinyl chloride or bromide into the corresponding aryl, heteroaryl, or vinyl iodide. Yet another embodient of the present invention relates to a tandem method, which may be practiced in a single reaction vessel, wherein the first step of the method involves the copper-catalyzed formation of an aryl, heteroaryl, or vinyl iodide from the corresponding aryl, heteroaryl, or vinyl chloride or bromide; and the second step of the method involves the copper-catalyzed formation of an aryl, heteroaryl, or vinyl nitrile, amide or sulfide from the aryl, heteroaryl, or vinyl iodide formed in the first step.

The invention discloses an n-type water and alcohol soluble conjugated polymer material containing a naphtho-diamide ring, and an application of the material. The material is in the following structure as shown in the description, wherein Ar is an aromatic group; A and B are hydrogen atoms or water and alcohol soluble strong polar groups; at least one of A and B is the water and alcohol soluble strong polar group; pi units are benzene, naphthalene, thiophene, bithiophene, selenophene, tellurophene, furan, pyrrole, silole, thiazole, oxazole, triazole or other conjugated units containing carbon-carbon double bonds and carbon-nitrogen bonds; m is an integer of 0 to 3; x is greater than 0 and less than 1; y is greater than 0 and less than 1; x plus y is equal to 1; and n is a natural number of 1 to 10000. The material can serve as an electron transfer layer with good charge transfer capability to be applied to luminous and photovoltaic photoconducting devices, etc., and a processing technology and the performance of the devices are improved.

A method for concentrating viruses includes applying a magnetic force to a mixture containing: sugar chain-immobilized magnetic metal nano-particles each having a structure in which a sugar chain-immobilized metal nano-particle is bound to a first magnetic nano-particle; second magnetic particles with mean particle size larger than that of the sugar chain-immobilized magnetic metal nano-particles; and a specimen. Each sugar chain-immobilized metal nano-particle has a structure where a ligand-conjugate is bound to a metal nano-particle via sulfur atoms. The ligand-conjugate has a structure where a linker compound's amino group is connected to a sugar chain having a reducing terminal. The linker compound includes, in molecules thereof, an amino group, sulfur atoms, and a hydrocarbon chain having carbon-nitrogen bonds. This allows short-time concentration of viruses in a sufficient amount almost equal to that of centrifugation concentration, allowing safely and effectively concentrating target viruses, resulting in prompt, easy, and highly sensitive detection and identification of viruses.

The invention provides nano coating comprising nano dispersion liquid, light-cured resin and auxiliaries. The nano dispersion liquid at least comprises nano materials and dispersants, the dispersants account for 5-50% of the weight of the nano materials, and the light-cured resin accounts for 100-600% of the weight of the nano materials. The auxiliaries at least comprise photoinitiators, adhesion promoters, flatting agents, surface anti-wear agents and diluting solvent. The dispersants and the light-cured resin form ionic bond or covalent bond combination, and chemical bonds at least include ester bonds, urea bonds, carbon-carbon bonds, carbon-nitrogen bonds and chemical bonds having the structural characteristics of -o-, carbamic acid ester, acid amide, acid imide, oxazolidinone and the like, so that re-agglomeration of the nano materials in films can be avoided, and further stability and weather resistance of the nano functional films are improved, and the service life of the nano functional films is prolonged. The nano coating further has the advantages of high visible light transmittance, high infrared barrier rate and high ultraviolet absorption rate.

A novel ligand conjugate which is effectively utilizable for analyzing a function of a protein; a ligand-supporting object; and a method of analyzing a protein. The ligand conjugate has a structure which comprises: a linker compound having a structure represented by the following General Formula (1):

(wherein n and p each is an integer of 0 to 6) in which X is a structure comprising one, two, or three hydrocarbon derivative chains which have an aromatic amino group at the end and may have a carbon-nitrogen bond in the main chain, Y is a hydro-carbon structure containing one or more sulfur atoms, and Z is a straight-chain structure comprising a carbon-carbon bond or carbon-oxygen bond; and a sugar which has a reducing end and is bonded to the linker compound through the aromatic amino group.

The invention provides a method for preparing a nitrogen-doped porous spherical disordered carbon material. The method comprises the steps of taking glycine and SiO<2> as a carbon-nitrogen source and a template agent; after performing spray granulation, carrying out high-temperature pyrolysis in argon atmosphere; and etching by using NaOH, and washing to obtain a target product. In the spray drying process, fine suspension liquid fog drops are rapidly dried by high-temperature airflow to form a spherical precursor which consists of glycine and SiO<2>; in the high-temperature pyrolysis process in the argon atmosphere, a part of carbon-nitrogen bonds are kept in the pyrolysis and carbonization of glycine, so that an effect of nitrogen doping is achieved; the prepared porous carbon spheres are mesoporous materials; the dimensions of the holes are about 10nm; the carbon spheres are uniform in particle diameter; the diameter of the carbon spheres is about 1-3[mu]m; the content of the doped nitrogen is about 10.86%; and the prepared nitrogen-doped porous spherical disordered carbon material, which is used as a negative electrode material of a lithium ion battery, has good electrochemical performance.

The invention relates to a polyamino-coated magnetic solid polyamino adsorbent granular material of which the particle size is 0.5-500.0 mu m. The granular material has the inorganic/organic multi-shell core-shell structure and the stable structure of connecting the polyamino adsorptive groups by carbon nitrogen bonds. The preparation method mainly comprises the following basic steps: (1) preparing an inorganic matter coating; (2) carrying out surface double bond modification; (3) preparing an organic matter coating; and (4) preparing the magnetic solid polyamino adsorbent granular material. The magnetic solid polyamino adsorbent granular material can generate selective chemical adsorption effects with heavy metal substances in a water body or solid-liquid suspension (mixed) system within a wide pH range, can be easily separated from the water body or solid-liquid suspension (mixed) system by a magnet or magnetic separator, is renewable and reusable, can implement centralized treatment on heavy metals, and can be widely used in environmental protection, pollution treatment, heavy metal substance recovery, mineral separation, hydrometallurgy and other industries.

A linker compound has a structure represented by general formula (1) below, where n is an integer of 1 to 6, and X has a structure serving as a multi-branched structure moiety including three or four hydrocarbon derivative chains each having an aromatic amino group at an end and a carbon-nitrogen bond in a backbone. A ligand includes the linker compound and a sugar introduced into the linker compound.

The embodiment of the invention provides sensitively responsive polymer nano-particles which comprise poly(cystamine bisacrylamide-alt-spermine) and polyethylene glycol-b-polylysine(2,3-dimethyl maleate); in poly(cystamine bisacrylamide-alt-spermine), a cystamine bisacrylamide monomer and a spermine monomer are connected through a carbon-nitrogen bond; in polyethylene glycol-b-polylysine(2,3-dimethyl maleate), a polyethylene glycol chain segment is methyl-polyethylene glycol-amino; one end of a polylysine chain segment is connected with the amino end of the polyethylene glycol chain segment through an amide bond; and 2,3-dimethyl maleate is connected with amino on the side chain of the polylysine chain segment through an amide bond. The sensitively responsive polymer nano-particles are good in stability and can be effectively enriched at a tumor site; loaded medicinal molecules can enter tumor cells easily; in addition, the sensitively responsive polymer nano-particles are good in biocompatibility and easy to degrade.

The invention belongs to the technical field of organic synthesis chemistry, and particularly relates to a synthetic method of aminoisoindole derivatives. According to the invention, continuous carbon-nitrogen bond construction is catalyzed by rare earth, so that synthesis of aminoisoindole derivatives with diversified structures is realized. Specifically, a compound 2-phenylethynyl benzonitrile and secondary amine are used as raw materials, and the aminoisoindole derivatives are prepared under a rare-earth catalysis system. According to the method disclosed by the invention, the raw materialsare wide in source or are easy to prepare, the operation is simple and convenient, selectivity is controllable, the yield is high, conditions are mild, and universality is wide.

The disclosure relates to a method for forming aryl carbon-nitrogen bonds and to photoreactors useful in these and other light-driven reactions. The method comprises contacting an aryl halide with an amine in the presence of a Ni salt catalyst solution and an optional base, thereby forming a reaction mixture; exposing the reaction mixture to light under reaction condition sufficient to produce the aryl carbon-nitrogen bonds. In certain embodiments, the amine may be present in a molar excess to the aryl halide. In certain embodiments, the Ni salt catalyst solution includes a Ni(II) salt and a polar solvent, wherein the Ni(II) salt is dissolved in the polar solvent. In certain embodiments, the reactions conditions include holding the reaction mixture at between about room temperature and about 80° C. for between about 1 hour and about 20 hours such that at least about 50% yield is obtained.

The invention discloses an N-heterocyclic carbene palladium complex crystal, a synthetic method thereof and application thereof in preparation of amide compounds. The structural formula of the complexcrystal is shown in the specification, or the complex crystal is prepared from an N-heterocyclic carbene ligand, Pd(CH3CN)2Cl2 and Ag2O in acetonitrile serving as a solvent. The N-heterocyclic carbene palladium complex crystal is relatively stable, wherein the raw materials used in the synthesis method are cheap and easy to obtain, so that the synthetic method is simple, convenient and easy to implement is simple in post-treamtent and is high in yield; and the N-heterocyclic carbene palladium complex crystal is used for catalyzing carbonylation carbon-nitrogen bond coupling reaction to prepare amide compounds and is high in catalytic activity, easy to operate and high in atom economy.

The invention discloses an immobilized glycosidase reagent. The immobilized glycosidase reagent comprises a thermo-sensitive magnetic fluid carrier material and glycosidase. The glycosidase is fixed to the thermo-sensitive magnetic fluid carrier material. The thermo-sensitive magnetic fluid carrier material comprises thermo-sensitive monomers, monomers with active functional groups capable of being combined with the glycosidase and magnetic nano-particles with an initiator for surface-initiated atom transfer radical polymerization. The thermo-sensitive monomers and the monomers with the active functional groups capable of being combined with the glycosidase are copolymerized into a polymer chain, the copolymerized polymer chain and the magnetic nano-particles are connected through coordinate bonds. The polymer chain and the glycosidase are connected through carbon-nitrogen bonds. By means of the immobilizated glycosidase reagent, the immobilized carrying amount of the glycosidase of unit mass immobilized glycosidase reagent and the stability of the immobilized glycosidase reagent are obviously improved, the enzymolysis efficiency is improved, the time needed by the thermo-sensitive magnetic fluid immobilized enzyme to complete glycoprotein enzymolysis is extremely short, the sample treating efficiency is obviously improved, the sample purity is improved, and the mass spectrum identification result is improved.

The invention discloses a His-Vx3-eGFP protein-nano aluminum covalent coupling ubiquitinated protein containing carbon-nitrogen bonds as well as an extraction method and application thereof. The ubiquitinated protein is prepared through the following steps of: forming a conjugate of His-Vx3-eGFP protein and modified nano aluminum by virtue of carbon-nitrogen double bonds and incubating the conjugate and a treated tumor cell lysis solution. Compared with the prior art, obtained alpha-Al2O3-His-Vx3-eGFP is stable in property, is capable of greatly improving the ubiquitinated protein collection effect and simplifying experiment operation; in addition, the defect that adjuvants are added in use of an existing ubiquitinated protein vaccine is overcome.

The present invention pertains to a coating film, and more particularly, to an antifogging coating film having excellent antifogging properties, ability to retain antifogging properties, and water resistance. The coating film according to the present invention contains a metal oxide (A) and a hydrophilic compound (B), wherein the elemental concentration ratio (C1s/M), which is between the element C and a metal element and which is obtained from a metal (M) spectrum derived from the metal oxide and a C1s spectrum in an elemental analysis of the surface using XPS, is within the range of 0.2-10. The relative elemental concentration of the element C obtained from a C1s spectrum derived from carbon-oxygen bonds and/or carbon-nitrogen bonds in elemental analysis of the surface using XPS may be within the range of 5-50 atomic %. The metal oxide may be colloidal silica. The coating film according to the present invention can be particularly preferably used as an antifogging coating film and a coating film for automotive exterior parts.

The invention discloses a preparation method of nitrogenous heterocyclic quaternary salt compounds,and belongs to the field of organic synthesis. In an organic solvent, Rh(III) serves as a catalyst,inthe presence of an additive and an oxidizing agent, substituent 8-methylquinoline and eneyne react at a heating condition, and subsequently, hexafluoroantimonate is added to react to obtain nitrogenousous quaternary salt. According to the preparation method of the nitrogenous heterocyclic quaternary salt compounds, substituent 8-methylquinoline serves as a substrate and reacts with preliminarilyprepared 1,3-eneyne to directly build carbon-nitrogen bonds and carbon-carbon bonds,and the nitrogenous heterocyclic quaternary salt compounds are efficiently synthesized. The preparation method has relatively mild reaction conditions, a wide substrate range, high efficiency and excellent regioselectivity.