The invention discloses a rapid combustible ice supercooling nano liquefier and a method for exploiting combustible ice with same, aims to achieve safe, environment-friendly, economic and effective combustible ice exploitation and has excellent development prospects. The rapid combustible ice supercooling nano liquefier comprises the following components in percentage by mass: 0-25% of ammonium salt, 0-25% of an acid, 10-80% of a penetrant, 0-25% of amide, 5-70% of an ester, 2-40% of an ether, 0-35% of an alcohol, 0-25% of ketone and 0-35% of aldehyde. According to rock ore components, the liquefier which has an ice point of minus 200 DEG C to minus 10 DEG C and is high in flash point, high in rock dissolution rate, large in permeability, low in injection pressure, rapid in injection pressure drop, long in effective supercooling liquid liquidation distance between single wells and group wells, large in volume, rapid in supercooling liquidation speed and safe and environment-friendly can be prepared, and low-cost large-scale long-term production of methane gas from combustible ice is rapidly achieved initially in the whole world.