43results about How to "Prevent postoperative infection" patented technology

The invention discloses a polylactic acid-based composite material surgical medical film and a preparation method thereof. By adopting electrostatic spinning equipment and exploring proper technological parameters, different types of polylactic acid-based composite material macromolecular fiber thin films are finally formed and are applied to the field of biomedicine. In addition, by regulating and controlling composition of a macromolecular composite material system and thickness of an electro-spinning thin film, the surgical medical film which has good flexibility, high tensile strength, controllable degradation rate as well as excellent waterproof, antibacterial and air permeable performances is obtained finally. The surgical medical film is applicable to the field of various biomedicines such as healing film, wound surface dressing and anti-adhesion medicine; the medical film not only can be better adhered to tissues and avoid biotoxicity, but also can effectively promote transmission functions of blood, nutrients and growth factors in a human body due to the nature of semipermeable membrane. The process of the invention is simple and environment-friendly; the preparation method is easy to operate, low in cost, applicable to large-scale production and good in controllability, and is expected to be widely applied to various medical fields.

The invention relates to a chitosan gel haemostatic material and a preparation method thereof. The chitosan gel haemostatic material is compounded of chitosan, a cross-linking agent and thrombin. The chitosan gel haemostatic material disclosed by the invention is good in biocompatibility and biodegradability; hydrogel is excellent in mucous membrane viscosity and self-adaptability, and has functions of quickly stopping blooding in body, promoting wound healing and releasing thrombin slowly so as to prevent secondary blooding caused by postoperative motion; meanwhile, the haemostatic material has characteristics of bacteria resistance and bacteriostasis and is capable of effectively preventing wound infection.

The invention belongs to the field of biomedical materials, and particularly relates to a biomedical material with good antibacterial, hemostatic and osteogenic activities and a porous calcium phosphate-chitosan composite coating, and a preparation method thereof. The preparation method comprises the following steps of: firstly, preparing a porous calcium phosphate coating by using plasma spraying; and secondly, directly compounding a water-soluble chitosan surface layer on the surface of the porous coating by a soaking method, a dropping method and the like. Thus, the prepared biomedical material not only can play a good role in resisting bacteria and stopping bleeding in early days after an operation, but also can minimize potential adverse effects of surface bioactivity and osteogenic performance of an implant. The biomedical material has a simple process and a low production cost, can endow an implantation appliance with two additional effects of stopping bleeding and stopping bleeding, can greatly improve the safety and the success rate of the existing implantation appliance, and alleviating pains of patients.

The invention discloses a polyether ketone ketone-based composite, a composition, a restoration, a preparation method and application thereof. The polyether ketone ketone-based raw material composition comprises the following components: the mass ratio of the polyether ketone ketone powder and the silicon nitride powder, the polyether ketone ketone powder and the silicon nitride powder is (1-3): (2-4), and the D50 particle diameter of the silicon nitride is 0.5-3.5 micrometres. The polyether ketone ketone-based composite disclosed by the invention has the advantages of promoting osteogenesis and biocompatibility, thereby promoting the adhesion, proliferation and differentiation of osteoblasts. The bone restoration can inhibit infection after being implanted into an organism, promote new bone regeneration, and ensure long-term stability of the implant. The preparation method of the polyether ketone ketone-based composite provided by the invention is simple and easy to operate, and the preparation process of the polyether ketone ketone-based composite can be adjusted according to the clinical requirement, so that the bone restoration with different shapes, specifications and mechanical properties can be prepared.

The invention discloses a bone repair material composition, a bone repair material and a preparation method and application of the bone repair material. The bone repair material composition comprisesa bone cement component and curing liquid, wherein the bone cement comprises magnesium oxide, calcium hydrophosphate, sodium dihydrogen phosphate and hydroxyapatite, and the curing liquid is a sodiumphytate aqueous solution. The bone repair material disclosed by the invention is simple to prepare and proper in coagulation time, has good biocompatibility, osteogenesis and degradability, can be directly injected into a bone defect part, has anti-osteoporosis performance and has an obvious osteogenesis effect.

The present invention relates to a bone repair material composition comprising a bone cement component and nano silicon nitride, wherein the bone cement component comprises magnesium oxide and sodiumdihydrogen phosphate, and the weight ratio of the nano silicon nitride to the bone cement component is 1: (1.5-9). The bone repair material prepared according to the invention has dual effects of resisting infection and promoting bone growth, not only inhibits bacterial adhesion, but also promotes adhesion and proliferation of osteoblasts, and can play a role in resisting infection and improving bony combination between an implant and a host bone after being implanted into a body.

The invention discloses a magnesium phosphate-based bone repair material, a raw material composition and a preparation method and application thereof. The raw material composition comprises the following components: mesoporous tantalum oxide and magnesium phosphate bone cement, the weight ratio of the mesoporous tantalum oxide to the magnesium phosphate bone cement powder in the magnesium phosphate bone cement is 1: 1.5 -9; and the particle size of the mesoporous tantalum oxide is 0.1-0.5 mu m and the pore diameter less than or 50 nm. The mixture of the raw material composition is solidified to obtain the magnesium phosphate-based bone repair material. The preparation method of the bone repair material is simple and feasible; the coagulation time is suitable, the biocompatibility, the osteogenesis and the degradability are good, the adhesion, the proliferation and the differentiation of osteoblasts can be promoted, the cell growth can be stimulated, and the osteoblasts can be stimulated to differentiate into osteocytes; and the magnesium phosphate-based bone repair material can be injected directly into bone defect; and the magnesium phosphate-based bone repair material loaded with stilbene glucoside has certain anti-osteoporosis performance and obvious osteogenesis effect.

The invention discloses a fixing system for treating fracture of tibial plateau. The fixing system comprises a locking steel plate and a plurality of screws, wherein the locking steel plate is externally arranged on a fracture part of the tibial plateau to fix the fractured tibial plateau; the locking steel plate is in an integral structure and comprises an opening annular plate and a straight plate; the opening annular plate is connected to one end of the straight plate; the opening annular plate circularly supports the fracture part of the tibial plateau; the other end of the straight plate is far away from the fracture part of the tibial plateau to support the far end of the fracture part of the tibial plateau; a plurality of thread holes are formed on the opening annular plate and the straight plate; and the screws are screwed into corresponding thread holes to fix and the opening annular plate and the straight plate. The fixing plate can treat seriously-damaged fractures of an opening tibial plateau or a closed tibial plateau soft tissues; infection or necrotic problems can be avoided; enough mechanical stability can be provided; the fixing system is light and practical as well as economic; and patient life can be facilitated and patient economic burden can be reduced.

The invention belongs to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine preparation for promoting caesarean section wound healing and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from astragalus membranaceus, angelica sinensis, codonopsis convolvulacea, atractylodes macrocephala, herba lycopi, hematoxylon, dahurian patrinia herb, leonurus, Chinese fevervine herb and root, hairyvein agrimony, tetrapanax papyriferus and liquorice as medicinal raw materials. The traditional Chinese medicine preparation has the effects of benefiting qi and nourishing blood, nourishing wei and consolidating superficies, promoting blood circulation to remove blood stasis, clearing away heat and toxic materials as well as constricting wound and generating muscle; by regulating functions of viscera of human bodies, principal factors 'deficiency' and 'stasis' which can affect wound healing are targeted, qi and blood are circulated, upper and lower and inside and outside parts can be connected, the whole body can be nourished, the healthy energy can be supported, comprehensive regulation and control functions of multi-target point, multi-procedure and multi-level can be achieved, postoperative wound healing can be improved, and postoperative infection and complications can be prevented. In addition, the traditional Chinese medicine preparation is an oral preparation which is free of toxic or side effect, puerperal lactescence can be also promoted, treatment compliance of patients can be greatly improved, and the living quality of the patients can be improved.

The invention discloses a preparation method of an anti-infective biological active coating on the surface of a 3D printed porous titanium stent. The method comprises the following steps: (1) preparing a porous titanium stent by using a 3D printing technology; (2) performing surface pretreatment by a sand blasting process, and then conducting annealing process treatment to form a smooth surface state on the surface of the porous titanium stent; (3) immersing the porous titanium stent in a sodium hydroxide solution for shaking; (4) rinsing the stent with deionized water or distilled water for several times, immersing the stent in the distilled water and a dilute hydrochloric acid solution respectively, then drying, heating up, keeping the temperature for a certain period of time and coolingthe stent with a furnace at room temperature; (5) preparing a simulated body fluid, adding vancomycin to the simulated body fluid, soaking the porous titanium stent in the simulated body fluid for shaking at constant temperature and obtaining the hydroxyapatite anti-infective bioactive coating with the vancomycin on the surface of the porous titanium stent. According to the method, the osseointegration, bone conduction and osteoinductive properties of the porous titanium stent can be significantly improved to achieve the purpose of preventing postoperative infection.

The invention discloses a post-operative anti-adhesion film material and a preparation method thereof. It belongs to the technical field of biomedical materials. The invention uses degradable biological materials such as konjac glucomannan and carboxymethyl cellulose with good biocompatibility. Sodium is the basic raw material, and the two are mixed to prepare a mixed sol. The modified sol is obtained through acid solution modification and microwave technology, and then the konjac glucomannan / carboxymethyl cellulose sodium composite is prepared by tape casting. Degradable membrane material to prevent adhesion after surgery. The degradation rate of the membrane material can be controlled by the double cross-linking degree of konjac glucomannan and carboxymethyl cellulose sodium. Not only the preparation process is simple and the cost is low, but also the Degradable membrane materials have good biomechanical properties. Cell experiments and animal experiments show that this membrane material can be widely used in the body and is an ideal degradable postoperative anti-adhesion material.

The invention provides a subcutaneous space builder and a using method thereof. The subcutaneous space builder comprises an inflatable ring, the inflatable ring is an annular air pipe after being inflated, a circular cavity is formed in the middle of the annular air pipe, and an inflating connector which can be connected with an inflating device is arranged on the outer wall of the inflatable ring. The subcutaneous space builder is placed in a subcutaneous layer, it can be achieved that a subcutaneous space which makes it convenient for a suture device to stretch into is built in the subcutaneous layer, and the abdominal wall incisional hernia can be directly sutured simply through the cooperation of the subcutaneous space and a peritoneoscope; meanwhile, the incision is small, the risk ofinfection is small, and the treatment fee is also low.

The invention provides a shapeable artificial bone plate. The shapeable artificial bone plate is made of biological absorbable materials. A bone plate body is round or square or trapezoid or the like and is of a symmetrical structure with a regular shape. The surface of the bone plate is coated with antibacterial materials. The bone plate is characterized by being capable of being shaped through heating during an operation. The shapeable artificial bone plate can be applied to a fenestration operation. According to the size of a window of a patient, the size of the bone plate can be customized, and postoperative infection and adhesion can also be effectively restrained.

The invention discloses a preparation method of a multifunctional GTR gradient barrier membrane. The multifunctional GTR gradient barrier membrane is prepared by a solvent pouring method. The method comprises specific steps as follows: preparing hollow carbonated hydroxyapatite; mixing the hollow carbonated hydroxyapatite with polylysine and agarose, and then preparing the multifunctional GTR gradient barrier membrane by the solvent pouring method. The invention also discloses an application of the multifunctional GTR gradient barrier membrane in regeneration of periodontal tissue and long-term antibiosis in oral environments. The process is simple, the requirement of ideal GTR barrier membrane can be met, the multifunctional GTR gradient barrier membrane can be prepared simply and conveniently by the method on a large scale, the prepared gradient barrier membrane can effectively prevent postoperative infection and promote repair of periodontal defect tissue after being applied to GTRoperation.

The invention discloses an automatic detector for air quality of a clean surgery room, which relates to the technical field of an air purification system. The automatic detector comprises a touch display screen, a data acquisition circuit board, a wind velocity indicator, a particle counter and an indoor differential pressure sensor. The touch display screen, the wind velocity indicator, and the indoor differential pressure indicator are connected with the data acquisition circuit board. The touch display screen is connected with the particle counter. The indoor differential pressure sensor comprises a cleaning area differential pressure sensor, a clean area differential pressure sensor and a front-chamber differential pressure sensor. The cleaning area differential pressure sensor, the clean area differential pressure sensor and the front-chamber differential pressure sensor are connected with the data acquisition circuit board. The automatic detector has advantages of high operation reliability, flexible adjustment and effective energy saving effect. The automatic detector performs functions of testing various parameters of the air in the surgery room, ensuring cleanness of the surgery room, effectively preventing after-surgery infection, and improving success rate of surgeries.

The invention provides an antibacterial heat conducting coating. The antibacterial heat conducting coating is characterized in that the antibacterial heat conducting coating comprises graphene oxide and antibacterial peptide, wherein the mass ratio of the graphene oxide to the antibacterial peptide is (1:25)-(1:75). The antibacterial heat conducting coating can reduce the postoperative infection phenomenon of organ transplantation, provide a stable internal environment for organs and have a good market prospect and a high value on social benefit.

The invention discloses an intraosseous self-reforming high-efficiency fracture reduction and fixation device, which comprises a body and an expansion fork. The expansion forks are respectively arranged on both sides of the body and are made of memory alloy materials. The invention is made of nickel-titanium memory alloy material, and is designed according to the characteristics of memory deformation of the material in the range of 0°C to 40°C, and in combination with ergonomics. When in use, the present invention closes the two expansion forks in ice salt water at 0°C to 5°C, drills the hole and puts it into the scaphoid from the fracture tubercle, wets it with hot salt water at 40°C on the fixation device, and uses The Martens effect of nickel-titanium memory alloy plate produces dynamic pressure, which is natural and soft, and makes the organs and bones integrated, stable and reliable, and is conducive to pressure reduction and fracture fixation. The invention is widely applicable, especially suitable for reduction and fixation of scaphoid fractures, does not need external fixation after internal fixation, is easy to operate, can avoid postoperative infection, and is beneficial to patients' early postoperative movement and recovery of wrist joint function.

The invention provides a neurosurgery drainage device, and relates to the technical field of drainage device manufacturing. A neurosurgery drainage device comprises a base, a rotating component, a drainage component and a lifting component. The drainage component comprises a drainage tube and a plurality of drainage containers. The lifting part is arranged on the base, a detachable part is arranged between the drainage tube and the drainage container, and the detachable part comprises an upper connector and a plurality of lower connectors. The lower connectors are vertically arranged on the drainage container in a one-to-one correspondence mode and communicated with the drainage container, the upper connector is communicated with the drainage tube, the free end of the upper connector can stretch into any lower connector, the free end of the upper connector and the lower connector form a quick connector structure, and the upper connector is arranged at the lifting end of the lifting component and can ascend and descend along with the lifting end of the lifting component. When the drainage container is full, the drainage container can be automatically replaced in time, the labor cost can be saved, and various problems caused by the fact that the drainage container is full and is not replaced in time are avoided.

The invention belongs to the field of biomedical materials, and particularly relates to a biomedical material with good antibacterial, hemostatic and osteogenic activities and a porous calcium phosphate-chitosan composite coating, and a preparation method thereof. The preparation method comprises the following steps of: firstly, preparing a porous calcium phosphate coating by using plasma spraying; and secondly, directly compounding a water-soluble chitosan surface layer on the surface of the porous coating by a soaking method, a dropping method and the like. Thus, the prepared biomedical material not only can play a good role in resisting bacteria and stopping bleeding in early days after an operation, but also can minimize potential adverse effects of surface bioactivity and osteogenic performance of an implant. The biomedical material has a simple process and a low production cost, can endow an implantation appliance with two additional effects of stopping bleeding and stopping bleeding, can greatly improve the safety and the success rate of the existing implantation appliance, and alleviating pains of patients.

The anorectal clinical postoperative analgesia and hemostasis device comprises a support, wheels, a liquid collecting basin, a flexible supporting rod and a clamping ring, the wheels are arranged at the four corners of the support, the liquid collecting basin is movably installed at the top end of the support, the flexible supporting rod is arranged on the inner side wall of the liquid collecting basin, and the clamping ring is arranged on the flexible supporting rod. The clamping ring is arranged at the upper end of the flexible supporting rod, a sengstaken-blakemore tube is installed on the inner side of the clamping ring, a first injector is installed at one end of the sengstaken-blakemore tube, and a third injector is installed below the first injector and connected to the sengstaken-blakemore tube. The device is simple in structure and convenient and reliable to operate and use, the three-cavity two-bag tube is used as a main component in the prior art, the cost is greatly reduced, and the device has high popularization and use value.

The invention discloses a high-safety and high-efficiency cleaning and disinfecting device for surgical instruments. The high-safety and high-efficiency cleaning and disinfecting device for the surgical instruments comprises a cleaning and disinfecting protective shell, wherein the cleaning and disinfecting protective shell is connected with an ultrasonic cleaning mechanism, the ultrasonic cleaning mechanism comprises a motor, the motor is connected with a cleaning main rotating shaft, and the cleaning and disinfecting protective shell is connected with a lifting pulling ring; a strong magnet is connected to the side, close to the cleaning main rotating shaft, of the lifting pulling ring, a water source pump is connected to the cleaning and disinfecting protective shell, a water source communicating pipe is connected to the water source pump, and a plurality of evenly-distributed ultrasonic vibrators are connected to the cleaning and disinfecting protective shell. Through the arrangement of corresponding mechanisms on the cleaning and disinfecting device, manual participation is greatly reduced, the cleaning and disinfecting cost is reduced, meanwhile, the cleaning and disinfecting efficiency can be improved, secondary cleaning of lumen type surgical instruments is avoided, a large amount of time is saved, meanwhile, postoperative infection caused by the lumen type surgical instruments can be avoided, and influence on body health of a patient is reduced.

The invention discloses a preparation method of a multifunctional GTR gradient barrier film. The multifunctional GTR gradient barrier film is prepared by using a solvent casting method. The specific steps are as follows: preparing hollow carbonated hydroxyapatite; making the hollow carbonated hydroxyapatite The multifunctional GTR gradient barrier membrane was prepared by solvent casting after mixing stone and polylysine with agarose. The invention also discloses its application in periodontal tissue regeneration and long-term antibacterial in oral environment. The process of the present invention is simple, and can meet the requirements of an ideal GTR barrier film. The method can be used to prepare a multifunctional GTR gradient barrier film in a simple and large-scale manner. The prepared gradient barrier film can effectively prevent postoperative infection when used in GTR surgery, and at the same time Promote the repair of periodontal defect tissue.

The invention discloses an intestinal wall fixing device of anenteroscope during surgery. The intestinal wall fixing device comprises an extension tube, wherein one end of the extension tube is provided with a first connector used for being connected with the intestine in an inserted mode; a plurality of elastic claws are arranged on the extension tube along the circumferential direction; one end of the elastic claw is fixedly connected with the extension tube, and the other end of the elastic claw extend towards the direction of the first connector; the elastic claws are externally covered with an elastic ring; the other end of the extension tube is provided with a second connector used for being connected with the enteroscope in the inserted mode; and the second connector is provided with a sealing structure. By means of an elastic fixing device, knotting and fixing in the surgery are omitted, and surgery time is saved; by arrangement of the extension tube, the intestinal wall fixing device can be placed out of an operation field, more intestinal canals are prevented from being dissociated, surgery wounds are reduced, and the surgery time is shortened; by arrangement of a radial incision and an air bag, air leakage and intestinal content overflow are avoided, abdominal cavity and operation field pollution is avoided, and postoperative infection is avoided; after the endoscope enters during the surgery, suction, decompression and flushing can be carried out, the conditions of obstructed near-end intestinal canals are observed, and lesion omission is avoided; and the intestinal wall fixing device has a simple structure and is convenient in operation.

The invention discloses a 3D printing porous scaffold with antibacterial functional coating and a preparation method thereof. The porous scaffold includes a scaffold body and an antibacterial coating. The scaffold body is shaped by SLM (selective laser melting) technology, and is formed by body-centered cubic unit accumulation. The antibacterial coating is constructed on the scaffold body surface by electrodeposition technology, and is a composite coating of silk fibroin composite and gentamicin. The method comprises the steps of: establishing a porous scaffold three-dimensional model, introducing the model into SLM equipment to conduct slicing; preparing metal powder to form a porous scaffold with optimized process parameters; preparing a silk fibroin / gentamicin mixed solution; carrying out electrodeposition of the antibacterial coating on the porous scaffold surface; taking out the porous scaffold and performing air drying so as to obtain the required porous scaffold. The method provided by the invention utilizes electrodeposition to continuously construct the silk fibroin / gentamicin composite coating evenly on the inner surface and outer surface of a Co-Cr porous scaffold formed by SLM, simplifies the preparation steps, reduces the cost, and can reach the purpose of preventing infection after joint replacement.

A corn removal nursing and treatment device acting on the sole of the foot, comprising: a console, a placement platform, a transmission device, a cutting device, a cleaning device, and a dressing device; wherein, the placement platform and the cutting device are arranged opposite to the cutting device, and the sole of the foot rushes toward the cutting device, The transmission device is fixedly connected with the cutting device, and is used to control the specific position of the spiral cutter in the cutting device. The cutting device is provided with a circular cutting blade, which can perform circular cutting according to the shape of the corns. The cleaning nozzle in the cleaning device is fixedly connected to the cutting device. , the dressing device is arranged on one side of the placement platform, and is used for dressing the postoperative wound; in the present invention, the doctor can control the operating device through the control console to perform the excision operation, and a unique knife is designed according to the growth shape and characteristics of the corn. The shape of the head can cleanly and thoroughly remove the inverted conical cuticle produced by the growth of corns, which ensures the efficiency and accuracy of the operation, saves artificial medical resources, and has high excision accuracy.

The invention discloses a fixing system for treating fracture of tibial plateau. The fixing system comprises a locking steel plate and a plurality of screws, wherein the locking steel plate is externally arranged on a fracture part of the tibial plateau to fix the fractured tibial plateau; the locking steel plate is in an integral structure and comprises an opening annular plate and a straight plate; the opening annular plate is connected to one end of the straight plate; the opening annular plate circularly supports the fracture part of the tibial plateau; the other end of the straight plate is far away from the fracture part of the tibial plateau to support the far end of the fracture part of the tibial plateau; a plurality of thread holes are formed on the opening annular plate and the straight plate; and the screws are screwed into corresponding thread holes to fix and the opening annular plate and the straight plate. The fixing plate can treat seriously-damaged fractures of an opening tibial plateau or a closed tibial plateau soft tissues; infection or necrotic problems can be avoided; enough mechanical stability can be provided; the fixing system is light and practical as well as economic; and patient life can be facilitated and patient economic burden can be reduced.

The invention provides an antibacterial and heat-conducting coating, which is characterized in that the antibacterial and heat-conducting coating contains graphene oxide and antibacterial peptide, and the mass ratio of graphene oxide and antibacterial peptide is 1:25-1:75. The antibacterial and heat-conducting coating of the invention can reduce postoperative infection of organ transplantation, and can provide a stable internal environment for organs, and has good market prospect and social public welfare value.

The invention provides a cholelithotomy sheath with an air bag, which comprises a tubular sheath body, a guide rod, a rubber cylinder, an air charging system and a closing device, wherein, the tubular sheath body is made of plastic material; two ends of the tubular sheath body are opened; an inserting end of the tubular sheath body is an oblique opening; the two ends of the rubber cylinder are opened; the two ends of the rubber cylinder are fixedly connected with a rubber cylinder mounting position of the tubular sheath body respectively; a rubber cavity is formed by the rubber cylinder and the rubber cylinder mounting position; radial air outlet holes are formed in an air guide passage positioned inside the rubber cylinder; the other end of the air guide passage is communicated with an air inlet pipe; the air inlet pipe is matched with the air charging system and the closing device; the guide rod is matched with the tubular sheath body in a detachable manner; and a guiding rod extends out of the inserting end of the tubular sheath body. By adopting the structure, the air charging system charges air and the rubber cylinder expands after the cholelithotomy sheath is inserted through a surgery incision of a gall bladder, and the rubber cylinder is jointed with the inner wall of the gall bladder after expanding, so that the tubular sheath body can be prevented from being withdrawn from the gall bladder; the cholelithotomy sheath is convenient to remove calculus, can prevent washing fluid entraining crushed calculus from flowing in an abdominal cavity through the incision of the gall bladder, enables the operation to be carried out smoothly, and avoids postoperative infection.