The invention discloses a method of extracting non-
alkaloid from fructus meliae toosendan and rhizoma
corydalis, relates to an extraction method of the non-
alkaloid and aims at solving the technical problems of the traditional method of extracting the non-
alkaloid of
low speed, high cost, need for
reflux high temperature, complex operation, high cost of extraction process and low extraction efficiency. The method comprises the following steps: mixing the rhizoma
corydalis and the fructus meliae toosendan,
grinding, adding an
ethanol aqueous solution, and carrying out ultrasonic treatment and
microwave heating; then carrying out ultrasonic treatment, filtering, collecting a filtrate,
steaming out
ethanol in the filtrate, adding water to regulate a pH value, and collecting an
ion exchange liquid containing the non-alkaloid component; and regulating a pH value to be 7, carrying out vacuum concentration, and
drying under vacuum to prepare non-alkaloid
powder. Compared with the decocting and
alcohol precipitation processes, the method has the following characteristics of rapidness in extraction, high extraction rate, low cost, high efficiency, no need for
reflux high temperature, simpleness and feasibility in operation, low cost of the extraction process and remarkable comprehensive economical benefit. The invention belongs to the field of extracting the non-alkaloid.