The invention discloses a supercritical carbon dioxide brayton cycle system belonging to the field of power station energy conservation. The supercritical carbon dioxide brayton cycle system mainly comprises a boiler furnace heating face, a boiler tail heating face, an air preheater, a boiler tail flue, a cycle working medium bypass pipeline, a high temperature regenerator, a medium temperature regenerator, a low temperature regenerator, a working medium turbine, a high-temperature gas compressor, an intercooling gas compressor and a cooler. The boiler furnace heating face is rearranged, a high-temperature regenerator bypass is arranged, thus the requirement of newly designed supercritical carbon dioxide cycle heat exchange is matched, cycle efficiency is improved, the utilization performance of low temperature smoke is improved, and heat absorption capacity distribution of the air preheater is improved and is optimized to be the same as the designed heat exchange capacity, corresponding to the air preheater, in coal steam cycle basically. Intercooling compression technology is adopted, cycle efficiency is improved, and the heat exchange interval of the cooler is optimized, thereby being matched with a water cooling system. In addition, the supercritical carbon dioxide brayton cycle system is simple in structure and high in operating efficiency and has good application prospects in engineering.