78 results about "Ruthenium catalyst" patented technology

The invention discloses a packaging material as well as a preparation method and application thereof. The packaging material comprises the following components in parts by mass: 40-85 parts of matrix resin, 5-30 parts of phase change PCM particles, 3-20 parts of self-repairing microcapsules, 1-8 parts of an interface compatilizer and 10-20 parts of a heat-conducting network reinforcing material, the melting point of the phase change PCM particles is not more than 80 DEG C; a core layer of the self-repairing microcapsule comprises dicyclopentadiene and a ruthenium catalyst, and a shell layer of the self-repairing microcapsule comprises polyurea or polyurethane; the PCBA packaging material with the intelligent response function is formed by combining the low-melting-point phase-change PCM particles with the self-repairing microcapsule system, when the PCBA temperature is too high, the low-melting-point phase-change PCM particles are molten, junction temperature suddenly rising is restrained through melting heat absorption, meanwhile, the adjacent microcapsules are triggered to be broken through volume expansion, DCPD monomers are released and subjected to in-situ polymerization under the action of a catalyst, and the PCBA packaging material with the intelligent response function is obtained. Microcracks generated by thermal stress are rapidly repaired, and the heat dissipation stability and the electrical insulation reliability of the material in long-term thermal circulation are remarkably improved.

This invention discloses a ruthenium catalyst supported on a phosphine-containing porous organic polymer and its preparation method. The phosphine-containing porous organic polymer serves as both a support and a solid ligand. The phosphine-containing porous organic polymer ligand is a random copolymer, and its structure can be represented by general formula I. The ruthenium catalyst supported on the phosphine-containing porous organic polymer according to this invention has a large specific surface area and contains a hierarchical porous structure, enabling efficient direct preparation of alcohols from olefins via reductive hydroformylation, and is easily recyclable. It exhibits excellent activity and regioselectivity in the direct preparation of alcohols from olefins via reductive hydroformylation, with an alcohol selectivity of nearly 90% and a high ratio of straight-chain alcohols to branched-chain alcohols.

The present invention relates to a method of preparing an organosulfur compound, and more particularly, to a method of preparing an organosulfur compound including a step of synthesizing an organosulfur compound by reacting specific compounds with a metal hypohalite under a ruthenium catalyst in a mixed solvent containing water and an organic solvent, wherein the metal hypohalite is introduced in a solid state and a portion thereof reacts in an undissolved state. According to the present invention, the present invention has an effect of providing an organosulfur compound preparation method capable of preparing an organosulfur compound in high yield due to excellent reaction stability, short reaction time, and reduced side reactions.

The invention discloses a toluene hydrogenation catalyst used at room temperature and normal pressure as well as a preparation method and application thereof, oxidation modified carbon nanofibers are adopted as a carrier, and face-centered cubic Ru is loaded on the oxidation modified carbon nanofibers in the form of nanoparticles through solvothermal reaction to obtain the toluene hydrogenation catalyst. The catalyst provided by the invention can efficiently catalyze toluene hydrogenation to generate methylcyclohexane under the conditions of room temperature and normal hydrogen pressure. Compared with a traditional catalyst, the carbon oxide nanofiber supported ruthenium catalyst not only can work under relatively mild conditions, but also can keep relatively high activity in long-time use, and provides a key support for low cost of an organic liquid hydrogen storage technology.

The invention provides a copper-ruthenium catalyst for photo-thermal catalysis of plastics and CO2 and a preparation method thereof, the catalyst takes TiO2-x with oxygen vacancy defects as a carrier, through solvothermal reduction and ligand regulation strategies, dispersion anchoring of Ru monatomic and in-situ formation of Cu clusters are realized, and a highly synergistic metal-carrier interface structure is constructed. The catalyst can efficiently break a polyethylene C-C bond to activate C-H dehydrogenation and promote CO2 to participate in redox cycle in a CD-ROM drive environment, the yield of H2 and CO and the selectivity of synthesis gas are improved, Ru monatomic and Cu atom clusters have a synergistic effect with a TiO2 oxygen defect interface, carbon deposition can be effectively inhibited, the reaction activation energy is reduced, the catalytic stability is improved, and the catalyst is suitable for industrial production. And an efficient and sustainable new path is provided for resource conversion of the waste plastics and CO2.

Certain embodiments of the invention provide a supported cationic Ru catalyst that is highly active in catalyzing olefin metathesis. Certain embodiments of the invention also provide a method of making a supported cationic Ru catalyst described herein, comprising contacting a Ru catalyst with a silylium-capped support.

The Invention relates to a method Method for making a ruthenium catalyst comprising the steps of - Providing an aromatic dithiol substituted on adjacent aromatic carbon atoms with thiol groups, wherein in a first step an aromatic compound substituted with two leaving groups on adjacent aromatic carbon atoms are reacted with alkali trithiocarbonate to obtain an aromatic benzodithiole-thione, which in a subsequent step is reacted / hydrolysed with a base; - providing a zinc dithiolate compound by reacting the aromatic dithiol with a zinc carboxylate in an organic solvent; Reacting the zinc dithiolate compound with a ruthenium compound wherein X1 and X2 are, independently of each other, are anionic ligands and are the same or different; L and L2 are, independently of each other, neutral electron donor ligands and are the same or different; Ar is an aromatic group which may be substituted and that can be bridged with L, if L is an alkoxy group; - Obtaining a ruthenium catalyst of formula 4 or 4a, wherein R1 to R4 are, independently of each other, are selected from hydrogen, halogen, alkyl, aryl, or R.1 with R3, R3 with R4 or R2 with R4 are forming together an aliphatic or aromatic ring.

The invention provides a nickel-iron-cobalt catalyst for AEM water electrolysis hydrogen production as well as a preparation method and application of the nickel-iron-cobalt catalyst. The preparation method of the nickel-iron-cobalt catalyst for AEM water electrolysis hydrogen production comprises the following steps: S1, dissolving nickel salt in water to obtain a nickel-containing solution, dissolving iron salt in water to obtain an iron-containing solution, dissolving cobalt salt in water to obtain a cobalt-containing solution, and dissolving sodium borohydride in water to obtain a sodium borohydride solution; s2, uniformly mixing the nickel-containing solution, the iron-containing solution and the cobalt-containing solution to obtain a mixed solution; s3, mixing and stirring the mixed solution and a sodium borohydride solution to generate a large amount of precipitate, and further cleaning, drying and grinding the precipitate to obtain the nickel-cobalt-iron oxygen evolution catalyst. The nickel-iron-cobalt catalyst provided by the invention can replace an iridium oxide (ruthenium) catalyst. The catalyst has low overpotential when applied to AEM water electrolysis hydrogen production, long-time effective electrolytic reaction can be guaranteed, and meanwhile the cost of an AEM electrolytic cell is remarkably reduced.

This invention provides a method for preparing a platinum-ruthenium catalyst for chlorine production, comprising: mixing nitrosylruthenium nitrate, platinum nitrate solution, deionized water, and a dispersant; heating to reflux temperature to dissolve; continuing the reaction at reflux temperature for 1 hour after the system changes from brownish-red to brownish-black; filtering the system after cooling to room temperature; and mixing the platinum-ruthenium mixture, silica hydrosol, and silica powder. The mixture is extruded into cylindrical pieces with a diameter of 5 mm, dried at 100-120°C for 6 hours to a breakage length of approximately 3-5 mm, and calcined in air at 200-240°C for 12 hours to obtain the platinum-ruthenium catalyst. This method can prepare a platinum-ruthenium catalyst with low chlorine impurity content that easily leads to catalyst aging. Simultaneously, because the reaction system remains acidic, the occurrence of ruthenium hydrolysis side reactions is reduced, resulting in a platinum-ruthenium catalyst with high yield, high ruthenium dispersion, and high catalyst activity.

To provide a method for producing a deuterated compound, by which the deuterated compound obtained by deuterating the hydrogen atom at the α - position of an α - amino acid or an α - hydroxy acid in high stereoselectivity can be produced in a high deuteration ratio in spite of a short time at a low cost, and which is also applicable to industrial production.SOLUTION: A method for producing a deuterated compound in which a hydrogen atom at an α - position of an α - amino acid or an α - hydroxy acid is deuterated, the method comprising allowing an α - amino acid or an α - hydroxy acid, heavy water, and hydrogen gas or heavy hydrogen gas to flow through a flow path filled with at least one catalyst selected from a ruthenium catalyst and a rhodium catalyst in the absence of a base to react the α - amino acid or the α - hydroxy acid with the heavy water.SELECTED DRAWING: None

The invention discloses a dioxetane chemiluminescent probe suitable for a biological orthogonal catalytic reaction as well as synthesis and application of the dioxetane chemiluminescent probe. A phenolic hydroxyl group active site of the probe is protected by an allyl bio-orthogonal cleavable group, and when a ruthenium metal complex catalyst is not added, the probe is in a silence state, and a chemiluminescence signal is weak; and in the presence of the ruthenium catalyst, the protecting group can be specifically catalytically cracked and removed, so that the probe is quickly activated and converted into a luminous'on 'state, and a strong chemiluminescence signal is generated. According to the invention, efficient combination of biological orthogonal cutting reaction and chemiluminescence signal output is realized, and the prepared biological orthogonal chemiluminescence probe has an excellent on-off ratio and is suitable for high-contrast biological imaging of living cell and living body levels.

The invention discloses a preparation method and application of a tetragonal biconical titanium dioxide supported ruthenium catalyst, and the tetragonal biconical titanium dioxide supported ruthenium catalyst is obtained by preparing a tetragonal biconical anatase TiO2 carrier through combination of a hydrothermal method and calcination and then carrying out hydrothermal in-situ loading and reduction of a ruthenium compound solution by using glucose. The core advantage of the catalyst is the dual synergistic effect of the carrier and the electronic state: the tetragonal bipyramid structure endows the catalyst with high stability, and the deactivation of the catalyst can be greatly reduced; the electron transfer of Ru to the carrier weakens the adsorption energy of cyclohexene, a high-proportion special electronic state Ru beta / Ru alpha is obtained, the surface hydrophilicity is optimized, and the rapid desorption of the target product cyclohexene is promoted. In addition, the cost is reduced by utilizing biomass reduction, the high dispersity of Ru is realized, and under the Ru loading capacity of 10wt.%, when the benzene conversion rate of the catalyst reaches 48.67%, the cyclohexene selectivity reaches up to 82.25%, and the cyclohexene yield reaches 53.22%.

This invention belongs to the field of catalyst technology, specifically relating to a supported iron-ruthenium catalyst and its application in the synthesis of m-dichlorobenzene and / or para-dichlorobenzene. The iron-ruthenium catalyst comprises a support and iron and ruthenium supported on the support. The support comprises quaternary ammonium salt-modified diatomaceous earth. Based on the total weight of the catalyst, the mass percentage of iron is 5-15%, and the mass percentage of ruthenium is 3-9%. The abundant active sites on the surface of the quaternary ammonium salt-modified diatomaceous earth support can significantly improve the catalytic activity and selectivity for m-dichlorobenzene and / or para-dichlorobenzene, without the formation of trichlorobenzene. The catalyst lifetime is 5-8 times longer than that of iron catalysts. The product can be separated and purified by stripping, distillation, and crystallization. The process is simple and can obtain high-purity m-dichlorobenzene and para-dichlorobenzene products.

The application discloses a polymer-coated mesoporous silica supported ruthenium catalyst and a preparation method and application thereof. The catalyst has a polymer-coated mesoporous silica inner core, wherein the surface of the silica inner core is grafted with triethoxysilane having an alkenyl group; the alkenyl group of the triethoxysilane serves as an active site; the polymer is formed by polymerization of a polymer monomer through the alkenyl group; and the catalyst is formed by further coordination of metal Ru. The particle size of the catalyst is between 400 nm and 600 nm. The supported ruthenium catalyst provided by the application can catalyze hydrogen transfer reduction of carbonyl compounds at a high yield (up to 99%) and high enantiomeric selectivity (up to 99%), can be recycled for 8 times through simple recovery, and is easy to be industrialized, and can reduce catalyst cost and pollution.

The invention discloses a synthesis method of 2-aryl-5-alkyl-3-pyridylthiophene, which comprises the following steps: by taking 3-pyridylthiophene, alkyl bromide and chlorobenzene as raw materials, catalyzing by using a ruthenium catalyst, and carrying out a three-component reaction by using a one-pot method to prepare the 2-aryl-5-alkyl-3-pyridylthiophene. According to the method, selective carbon-hydrogen bond activation of C2 and C5 sites of 3-pyridyl thiophene is realized by utilizing a ruthenium catalyst, so that precise bifunctional modification is completed in a single reaction system. According to the invention, the 2-aryl-5-alkyl-3-pyridyl thiophene with a clear structure is successfully constructed, and the technical vacancy of related fields in the aspect of regioselective one-pot bifunctionalization is made up. Compared with a traditional fractional step method, the method has the advantages of simplified reaction steps, convenience in operation, good functional group compatibility, relatively high chemical selectivity, regioselectivity, atom economy and the like, is suitable for efficient construction of various heterocyclic compounds, and has a good application prospect.

The invention discloses a method for preparing chain-length-controllable alkyl aromatic hydrocarbon by directionally converting thermoplastic plastic through a hierarchical pore MFI nanosheet supported ruthenium catalyst. The method comprises the following steps: mixing thermoplastic plastic, an MFI nanosheet carrier loaded ruthenium catalyst and cyclohexane, stirring and reacting for 9-18 hours in an inert atmosphere at the pressure of 0.1-1.0 MPa and the temperature of 230-250 DEG C to obtain alkyl aromatic hydrocarbon with controllable chain length, and controlling the ratio of the specific surface area of micropores to the sum of the specific surface areas of mesopores and macropores to be (0-1): (1.6-606) by controlling the stirring time to obtain the alkyl aromatic hydrocarbon with controllable chain length. The side chain length distribution of the obtained alkyl aromatic hydrocarbon main product is concentrated on 1-3 continuous carbon numbers in C2-C24, and the difference value of the number of carbon atoms is less than 3, so that the contradiction between the diffusion limitation of a macromolecular polymer and the product selectivity is effectively solved. The yield of the obtained alkyl aromatic hydrocarbon is up to 67.4-75.0%, the selectivity is up to 72.8-83.4%, and the industrial application value is remarkable.

The application belongs to the technical field of organic synthesis, and particularly relates to a preparation method of maropintan and an intermediate thereof. The preparation method comprises the following steps: S1: 3-quinuclidinone or a salt thereof is reacted with benzophenone under the condition of a base, a first solvent, to obtain 2-(diphenyl methylene) quinuclidin-3-one; S2: the obtained 2-(diphenyl methylene) quinuclidin-3-one is reacted with an amine source and hydrogen under the condition of a chiral ruthenium catalyst, an optional additive and a second solvent, to obtain an intermediate (2S, 3S)-2-diphenyl methyl quinuclidin-3-amine; and S3: the obtained (2S, 3S)-2-diphenyl methyl quinuclidin-3-amine is subjected to a condensation reaction with 5-tert-butyl-2-methoxy benzaldehyde (formula V) in the presence of an acid and a third solvent, and is reduced by palladium carbon or platinum carbon and hydrogen to obtain maropintan. The method has the advantages of low-cost and easily-available raw materials, a short synthesis route, high-yield one-step reaction of double chiral centers, good selectivity, simple process, high product yield and low cost.

The present disclosure provides a method for catalytic hydrogenation of trisubstituted acetate or tertiary alkyl ester, comprising the following steps: performing a hydrogenation reaction by using a trisubstituted acetate or tertiary alkyl ester as a substrate in the presence of hydrogen and a manganese catalyst or a manganese catalytic system; the manganese catalyst is selected from compounds represented by formula (1): According to the present disclosure, a metallic manganese catalyst is used to achieve hydrogenation reduction of trisubstituted acetate or tertiary alkyl ester, which, compared to precious metal ruthenium catalysts, has advantages of low costs, easy availability, and low toxicity; and compared to existing inexpensive metal copper or cobalt catalysts, has advantages such as broad substrate applicability, mild reaction conditions, and high yield of target products.

The invention discloses a method for preparing a chiral amine compound through asymmetric hydrogenation of ruthenium catalyzed imine. The chiral ruthenium catalyst is a chiral metal ruthenium complex prepared by reacting metal ruthenium salt with a chiral phosphine-phosphoramidite ester ligand and chiral diamine in a solvent and carrying out column chromatography. Compared with other chiral amine synthesis methods, the method provided by the invention has the characteristics of cheap catalyst, easy preparation of chiral ligand, mild reaction conditions, simple operation, high yield and enantioselectivity and the like, and can be applied to large-scale preparation of chiral amine compounds. The method is also suitable for synthesis of the key intermediate of the herbicide (S)-metolachlor, the yield can reach 92%, the enantioselectivity can reach 90%, and the method has good industrial application prospects.

The invention provides a method for catalytic synthesis of aripiprazole by using a hydrogen transfer strategy, and the preparation method comprises the following steps: taking 7-hydroxy-3, 4-dihydro-2 (1H)-quinolinone as a starting material, and carrying out nucleophilic substitution type etherification reaction on the starting material and 4-bromo-1-butanol in an alkaline medium to generate a 7-(4-hydroxybutoxy)-3, 4-dihydro-2 (1H)-quinolinone intermediate; and then, by taking a ruthenium catalyst as a catalytic system, carrying out N-alkylation reaction on the intermediate and 1-(2, 3-dichlorophenyl) piperazine hydrochloride to finish the synthesis of the target compound aripiprazole. The method has the advantages of being short in technological process, high in atom utilization rate, high in yield, low in cost, environmentally friendly and the like.

The invention relates to a preparation method of a drug intermediate. Specifically, the invention relates to a preparation method of a compound as shown in a formula (I) or a salt thereof, and the preparation method comprises a step of carrying out hydrogenation reaction on a compound as shown in a formula (II) or a salt thereof under the action of a metal ruthenium catalyst. The method has relatively high catalytic activity and process stability, is low in cost and is beneficial to industrial production.

The invention belongs to the technical field of organic synthesis, and particularly provides a preparation method of a Ramage linker intermediate. The preparation method of the Ramage linker intermediate according to the embodiment of the invention comprises the following steps: step S1, enabling 2-vinyl benzoic acid to react with 3-methoxystyrene under the action of a ruthenium catalyst to generate the Ramage linker intermediate 2-(3-methoxyphenyl) vinyl benzoic acid; according to the preparation method of the Ramage linker intermediate disclosed by the embodiment of the invention, the preparation of the intermediate can be realized in one step through the olefin metathesis reaction, the reaction is mild, the post-treatment is simple, the synthesis route is simplified, tedious conversion and violent reaction conditions are avoided, and the reaction safety coefficient is improved.

The application discloses a ruthenium-based ammonia synthesis catalyst with alumina as a carrier and a preparation method thereof. The catalyst is prepared by the following steps: first, impregnating alumina with a water solution containing carbon-containing organic matters, and then high-temperature heat treatment in an oxygen-containing atmosphere to obtain an alumina carrier; then, introducing cerium additives by a precipitation method, and calcining in an inert atmosphere; then, introducing active components ruthenium and performing heat treatment in a carbon-containing gas; and finally, reduction to obtain the catalyst. Compared with the alumina-supported ruthenium catalyst prepared by the prior art, the catalyst prepared by the application has higher ammonia synthesis activity, and has a good application prospect.

The application provides a porous medium combustion device for catalytic pyrolysis combustion of ammonia, in which ammonia is preheated in a catalytic pyrolysis reactor, and is partially pyrolyzed into nitrogen and hydrogen through a heterogeneous ruthenium-free catalyst, and the mixed gas (NH3, N2 and H2) after pyrolysis is introduced into a porous medium combustor to combust after being fully preheated in a premixing zone; the combustion flue gas is used for preheating of ammonia in the catalytic pyrolysis reactor, the flame propagation speed is improved, the combustion stability of the NH3 / H2 / air mixture is increased, and the flammability limit is improved; the high-temperature flue gas generated by combustion is heat-exchanged through a heat exchanger, on the one hand, energy is externally delivered, and on the other hand, through the coupling structure of the heat exchanger and the catalytic pyrolysis reactor, ammonia is preheated to a temperature range of 300 DEG C-500 DEG C and is used for catalytic pyrolysis of ammonia, without external energy input, and the combustion efficiency is improved.

The present application relates to the technical fields of compound synthesis and catalysis, and particularly relates to a precursor compound for preparing a ruthenium catalyst with an oxygen-locked chain type semi-sandwich structure, an intermediate and a preparation method thereof, the precursor compound has the following general formula: wherein R1 is a p-toluenesulfonyl group or a methanesulfonyl group. The synthesis path of the precursor compound is shown as follows: The present application also provides application of the precursor compound in preparation of a key intermediate of a ruthenium catalyst. The method has mild reaction conditions (0-50 DEG C), simple operation, high yield, and the raw materials are easy to obtain, and the purification process is simple, and is suitable for industrialized production.

The application relates to the technical field of organic synthesis, and particularly relates to a preparation method of alpha, beta-unsaturated carboxylic acid ester, which comprises the following steps: mixing a ruthenium catalyst, an organic nitrogen ligand, a 1,2-propadiene compound and an alcohol compound under the condition of carbon monoxide, and then performing reaction to obtain alpha, beta-unsaturated carboxylic acid ester. The application adopts the 1,2-propadiene compound to perform a hydrogen esterification reaction to efficiently prepare alpha, beta-unsaturated carboxylic acid ester; through the regulation of the organic nitrogen ligand on the ruthenium catalyst, the target product can be efficiently and highly selectively synthesized, and the application has a good industrialization prospect; meanwhile, in the preparation method, the reaction condition is relatively mild, excellent conversion of the substrate can be realized at a relatively low reaction temperature, catalyst deactivation can be effectively avoided, and the conversion rate of the substrate and the yield of the product are relatively high. In addition, the application is widely applicable, and can be used to synthesize various types of alpha, beta-unsaturated carboxylic acid ester in one step.

The invention discloses a manganese-doped ruthenium oxide nano-catalyst, a preparation method thereof, an electrode and a water electrolysis hydrogen production device, and relates to the technical field of catalytic materials. The molar ratio of ruthenium to manganese in the catalyst is (5-9): 1; the average particle size of the catalyst is 6-8 nm. The manganese element is introduced to construct a stable composite structure, the structural stability is greatly improved while high intrinsic activity is maintained, in addition, good oxygen evolution and corrosion resistance are achieved, water oxidation of the acid electrolyte is driven at a low potential, good stability is maintained, and the service life of the acid electrolyte is prolonged. And the defect of poor stability of a commercial ruthenium oxide catalyst in an acid medium is overcome. The catalyst can well adapt to large-scale hydrogen production application in the future, and reaches the application standard of clean energy in the future. The preparation method belongs to one-pot molten salt synthesis, is simple, convenient and efficient in preparation, and provides a key material solution for an efficient and long-life proton exchange membrane water electrolysis hydrogen production technology.

The invention discloses a synthetic method of (R)-glabridin with high optical purity, and belongs to the technical field of organic synthesis. The synthesis method provided by the invention comprises the following steps: dissolving methyl-protected isoflavone in a solvent, and adding boron tribromide to carry out a protecting group removal reaction; then carrying out asymmetric hydrogen transfer reaction on a reaction product in an acid-base mixed solution under the action of a chiral ruthenium catalyst; and finally, in the presence of acid, carrying out dehydroxylation reaction on the reaction product and a silane reagent in a solvent to obtain the (R)-glabridin. The (R)-glabridin is efficiently synthesized with high selectivity through a simple three-step reaction, the total yield is high, the optical purity is excellent, the conditions are mild, the post-treatment method is simple, and the method is suitable for large-scale production.

The invention discloses a synthesis method of a 2-alkynyl-3-ester pyrrole compound, which comprises the following steps: by taking a pyrrole derivative and (bromoethynyl) triisopropyl silane as raw materials, under the conditions of a silver additive and alkali, catalyzing a pyrrole C2 site direct alkynylation reaction by using a ruthenium catalyst to prepare the 2-alkynyl-3-ester pyrrole compound. The method is based on a precise C-H activation strategy of a ruthenium catalyst, and through reasonable matching of the ruthenium catalyst, a silver salt additive and an alkali system, the activity of a metal center can be effectively regulated and controlled, so that the metal center selectively recognizes a pyrrole C2 site and precise and directional introduction of alkynyl is realized, thereby overcoming challenges such as site competition and catalytic circulation blocking caused by an electronic effect. In a word, the alkynylation system established by the invention is simple and convenient to operate and good in repeatability, provides a reliable technical approach for rapid preparation of the 2-alkynyl-3-ester pyrrole compound, expands a new synthesis thought for construction of drug molecules, functional materials and organic photoelectric structural units, and has important application value and popularization prospect.