33results about How to "Appropriate mechanical strength" patented technology

The invention belongs to the field of biomedicine, in particular to a bionic II type collagen hyaloplasm acid compound sponge bracket for repairing cartilage in tissue engineering. The preparation method of the II type collagen hyaloplasm acid compound sponge bracket comprises the following steps of: extracting high-purity II type collagen solution; concentrating the II type collagen solution by means of a polyethylene glycol concentration method; gradually mixing hyaloplasm acid solution with the high-purity II type collagen solution by means of a partial homogenate method; and crosslinking the concentrated II type collagen hyaloplasm acid compound sponge with EDC and NHS dual cross-linking agent to obtain the II type collagen hyaloplasm acid compound sponge bracket. The II type collagenhyaloplasm acid compound sponge bracket can be taken as a tissue engineering implant, a cell culturing bracket material or medicine controlled release and the like for the prevention and the cure of the repair of the cartilage injury.

The present invention relates to a non-heat treated magnesium alloy sheet which can substantially reduce casting defects such as center segregation and inverse segregation and has excellent formability when compared with a conventional commercial magnesium alloy sheet by controlling an alloy composition. The magnesium alloy sheet according to the invention comprises 1-3 wt% of Al, 0.5-3 wt% of Sn and the remaining amount of magnesium, and the difference of the mean value of Vickers hardness (Hv) caused by center segregation and inverse segregation is 10Hv or less.

The invention relates to a medical composite material, in particular to a PVA fiber polyamino acid hydroxyapatite composite bone support material and a preparation method thereof. The invention provides a composite bone repair material. The bone repair material is composed of polyamino acid polymer, polyvinyl alcohol fiber, calcium phosphate salt and coupling agent, and the mass ratio of each raw material is: calcium phosphate salt 20% to 50%, poly Vinyl alcohol fiber 15-30%, polyamino acid polymer 20-55%, coupling agent 1-5%. The PVA fiber polyamino acid calcium phosphate composite material obtained in the present invention has high strength, high toughness and high elastic modulus, and can be made into a supporting bone repair implant by rapid injection molding or hot pressing molding, and the obtained supporting bone repair implant The bending strength of the material is 120-160MPa, the bending modulus is 5-15GPa, the compressive strength is 120-180MPa, and its biomechanical properties are close to those of human bone tissue.

The invention relates to a bionic artificial skin, comprising a protective layer, an epidermis and a dermis, characterized in that the protective layer is composed of a non-degradable or slowly degradable polymer film containing micropores, and the epidermis is composed of a microporous structure Composed of biodegradable and absorbable biopolymers, the dermis is composed of biodegradable and absorbable biopolymer sponges. The protective layer has a waterproof and moisture-permeable function. The material of the epidermis is the same as that of the human epidermis, and has a microporous structure, which can make the artificial skin have oxygen and moisture permeability similar to that of human skin, and endow the artificial skin with a breathing function. The composition of the epidermis and dermis Capable of degrading, because the ingredients are close to autologous skin, the degradation products help to promote the regeneration of epidermal cells and fibroblasts. The invention also provides a preparation method of the bionic artificial skin.

The invention relates to the technical field of new materials and relates to a preparation method of a crosslinked chitosan / hyaluronic acid compound porous scaffold. According to the preparation method, natural biological materials such as chitosan and hyaluronic acid are used as raw materials and an organic silane coupling agent KH-560 is used as a crosslinking agent, and the crosslinked chitosan / hyaluronic acid compound porous scaffold which is made of purely natural biological materials and is excellent in mechanical property is prepared adopting a freeze-drying method. The crosslinked chitosan / hyaluronic acid compound porous scaffold prepared by adopting the preparation method has the characteristics of high porosity, high pores strength, large pores diameter and the like, is of an open type pore structure that small pores are contained in large pores, and is suitable for planting cells on the surface of the scaffold, wherein the pore diameter is 100-300 mu m and porosity is more than 90%. Compared with a chitosan scaffold, the crosslinked chitosan / hyaluronic acid compound porous scaffold has the advantages that the mechanical property is better; proliferation and differentiation effect of the cells on the surface of the porous scaffold is better due to the addition of the organic silane coupling agent, and affinity to biological cells is better.

The invention provides a self-adhered type anti-neutron composite shielding material as well as a preparation method and application thereof. The shielding material is prepared from the following raw materials in parts by weight through radiation pre-crosslinking treatment: 100 parts of a rubber susbtrate, 5-50 parts of a tackifying agent polymer, 10-100 parts of a reinforcing agent, 20-200 parts of an anti-neutron additive, 0-50 parts of a softening agent, 0.5-10 parts of a vulcanizing agent, 0.5-5.0 parts of a vulcanization promoter, 0.5-10 parts of a vulcanization activator and 0-5.0 parts of an anti-aging agent. The invention further provides a preparation method of the shielding material and application of the shielding material in complex equipment or irregular parts. The self-adhered type anti-neutron composite shielding material provided by the invention has certain initial crosslinking degrees and self adhesion properties, is good in shape flow property, can be cured by self after being shaped, and has appropriate mechanical strength.

The invention belongs to the technical field of novel materials and in particular relates to a method for preparing a crosslinked chitosan porous scaffold. The method comprises the following steps: by taking a chitosan natural biomaterial as a raw material and an organic silane coupling agent KH-560 as a cross-linking agent, preparing the crosslinked chitosan porous scaffold which is excellent in mechanical property and consists of pure natural biomaterials by adopting a freeze drying method. The prepared crosslinked chitosan porous scaffold has the large pore diameter of 100-300 mu m and the high porosity of more than 90 percent, is in an open hole structure in which a large pore contains a small pore, and is suitable for cell implantation on the scaffold surface. Compared with a chitosan scaffold, the crosslinked chitosan porous scaffold has higher mechanical property; due to the added organic silane coupling agent, the cell proliferation and differentiation on the surface of the porous scaffold are promoted, and the affinity to biological cells is high.

The invention relates to the field of polyvinyl alcohol films, in particular to polyvinyl alcohol matte films, compositions and preparation methods thereof. The polyvinyl alcohol composition contains polyvinyl alcohol, a plasticizer, olefin-maleic anhydride copolymer microspheres, a lubricant and optional auxiliary agents; the plasticizer contains component A, component B and component C; the component A is one or more of glycerol, ethylene glycol, polyethylene glycol and pentaerythritol; the component B is magnesium chloride, magnesium nitrate, calcium chloride, copper sulfate and sodium acetate One or more; the component C is water. The present invention can make polyvinyl alcohol with a wide range of alcoholysis degree to be biaxially stretched into a film, and the obtained polyvinyl alcohol matte film has a matte effect, and also has suitable mechanical strength, surface wetting tension and Translucency.

The invention relates to the technical field of novel materials, and in particular relates to a method for preparing a chitosan / hyaluronic acid / gelatin crosslinked composite porous stent. The method uses chitosan, hyaluronic acid, gelatin and other natural biological materials as raw materials and dialdehyde starch as a crosslinking agent, and combines a lyophilisation method and a particulate leaching method to prepare the chitosan / hyaluronic acid / gelatin crosslinked composite porous stent, which is excellent in mechanical performance and made of a pure natural biological material. The chitosan / hyaluronic acid / gelatin crosslinked composite porous stent prepared by the method has the characteristics of high porosity, high pore strength, large pore diameter and the like, the pore diameter is 100-300 mu m, and the porosity is more than 90 percent. The stent is of an opening pore structure with small pores in large pores, and is suitable for cell implanting on the surface of the composite stent. Compared with a chitosan stent, the crosslinked composite porous stent has a better mechanical performance, proliferation and differentiation of cells on the surface of the composite stent can be more favored, and the compatibility of the composite stent to biological cells is excellent.

Provided is an LED filament, comprising: an LED filament substrate, the LED filament substrate comprising a filament substrate and several LED chips arranged on the filament substrate, the filament substrate comprising a cylindrical substrate, an outer surface of the filament substrate being provided with several recesses, the LED chips being arranged in the recesses of the filament substrate, the LED chips radially distributed on the outer wall of the filament substrate being electrically connected; a flexible glass film, the flexible glass film being seamlessly coated on surfaces of the recesses, the flexible glass film being a flexible fluorescent glass film, the flexible fluorescent glass film containing a glass powder, a fluorescent powder and graphene, the weight ratio of the glass powder, the fluorescent powder and the graphene in the flexible fluorescent glass film being (5-6):1:(0.1-0.5).