The invention discloses a compound feed for penaeus vannamei and belongs to the field of formulas of feeds for shrimps. The compound feed is prepared from the following components in parts by weight: 50-70 parts of corn, 30-40 parts of bran, 10-20 parts of shell powder, 3-10 parts of brewer's grains, 2-5 parts of salt, 3-6 parts of spirulina, 3-6 parts of soybean oil, 10-20 parts of reed powder, 5-10 parts of amino acid mixture, 2-6 parts of microelement, 5-10 parts of binder, 1-5 parts of calcium hydrophosphate, 3-5 parts of eggshell, 2-5 parts of yeast powder and 2-5 parts of complex vitamins. The compound feed for penaeus vannamei is used for solving the problems of slow growth, weak disease resistance and low survival rate of the penaeus vannamei; the compound feed provides comprehensive and sufficient nutrition for the penaeus vannamei, can be quickly ingested by the penaeus vannamei and also can be effectively digested, absorbed and utilized, and therefore, the penaeus vannamei is promoted to grow quickly and the survival rate of the penaeus vannamei is high; the compound feed is good in stability in water and can be ingested by the penaeus vannamei better; as a result, the loss of nutrient substances is effectively reduced, the eutrophication pollution on the aquatic water is reduced and the sustainable development of the shrimp industry is effectively promoted.