The invention belongs to the field of rare earth permanent magnetic materials, and particularly provides a method for preparing a dense fine-grain neodymium iron boron sintering magnet. The method for preparing the dense fine-grain neodymium iron boron sintering magnet is characterized in that vacuum pre-sintering is conducted before high-pressure argon hot isostatic pressure sintering, the sintering temperature is kept between +5 DEG C and 50 DEG C of the eutectic temperature of a 2:14:1 phase and a phase rich in neodymium, and the pressure range is between 2MPa to 20MPA in the isostatic pressure sintering process. The method particularly comprises the steps that after ingot casting, powder preparation and orienting profiling are sequentially conducted on neodymium iron boron alloy, the neodymium iron boron alloy is placed in a sintering furnace, after the high vacuum condition is met, the neodymium iron boron alloy is heated, the sintering furnace is vacuumized continuously, the high vacuum environment is created through stage heating and control over the heating speed, when the required sintering temperature and the required vacuum degree are achieved, the neodymium iron boron alloy is pre-sintered for a certain time in a vacuum mode, then, vacuumization is stopped, high-purity argon is gradually conveyed to the sintering furnace so that isostatic pressure can be exerted, the temperature is continuously kept for a certain time, rapid cooling is conducted, and therefore the product is obtained. The method for preparing the dense fine-grain neodymium iron boron sintering magnet has the advantages that a dense and fine-crystalline structure can be sintered, shrinkage of the product is even, properties are identical, operation is simple, and the method is suitable for industrialized production.