6 results about "Extinction spectrum" patented technology

The invention discloses a double-optical-path spectrum system for turbidity measurement and interference compensation, which comprises a double-optical-path spectrum measurement system, and the double-optical-path spectrum measurement system comprises a light source, and an optical path collimation and switching system, a double-optical-path measurement system, a transmission measurement system and a scattering measurement system which are electrically connected, the particle size distribution and extinction spectrum of the water body are reconstructed by combining a spectral analysis algorithm, and turbidity measurement and interference compensation are carried out on the water body. Sampling is carried out by adopting a dual-optical-path technology; scattering signals of a water body to-be-measured sample are measured by combining sampling data with an integrating sphere so as to verify the influence of the scattering signals, particle size distribution of water body particles is reconstructed by utilizing a light total scattering method, and a particle reconstruction wave band is determined by adopting a mode of reconstructing a comparison standard solution in multiple wave bands; secondary inversion of an extinction spectrum is carried out according to a reconstruction result, accumulation correction is carried out by using multiple groups of compensation results of different filter membranes of adjacent gradients, and the accuracy of a later turbidity compensation result is improved.

The present disclosure provides an integrating-sphere-assisted resonance synchronous (ISARS) spectroscopy method performed with an ISARS spectrophotometer, for example, a spectrofluorometer equipped with an integrating-sphere accessory. The methods and systems of the present disclosure utilize the ISARS spectrophotometer equipped with an integrating sphere to determine the ISARS spectral intensity, quantify the ISARS-based absorbance, and subsequently evaluate the sample's double-beam UV-vis absorbance spectrum (also known as the absorption extinction spectrum). This ISARS method enables quantitative separation of light absorption and scattering contribution to the sample UV-vis extinction spectrum measured with double-beam UV-vis spectrophotometer.

The present invention relates to a method for quantitative analysis of a plurality of components in at least one aqueous sample comprising an active pharmaceutical ingredient (API), the method comprises the steps of (a) providing at least one aqueous sample comprising a plurality of components, wherein the sample comprises a biologic API; (b) measuring the extinction spectrum of the at least one aqueous sample using a Fourier transform infrared (FT IR) spectrometer comprising a transmission flow-through cell in a single measurement; (c) providing at least one reference extinction coefficient spectrum for each component of the plurality of components to be analyzed in the at least one aqueous sample; and (d) quantifying the concentration of each component in the plurality of components to be analyzed in the at least one aqueous sample based on the reference extinction coefficient spectra of step (c) and the extinction spectrum of the at least one aqueous sample of step (b) by solving the classical least square (CLS) problem by an algorithm using a numerical linear algebra method for finding the approximate solution to an overdetermined system of linear equations characterized by the Beer-Lambert law for the extinction spectrum of the at least one aqueous sample. The invention further relates to methods for the production of an API or determining the purity of an API comprising using said method.

The present application relates to a kind of particle size and mixing ratio measurement method, device, electronic equipment and storage medium, comprising: by extinction method measurement to the two-phase system mixed with first solid particles and second solid particles obtains corresponding experimental extinction spectrum, first solid particles and second solid particles are two different types of solid particles.By calculating the extinction coefficient of first solid particles and second solid particles under the action of light wave is obtained.By calculating the albedo of first solid particles and second solid particles, and judging whether corresponding photon is scattered.If photon is scattered, the scattering angle when photon is scattered and the random free step length between adjacent two scattering of photon are obtained.According to the direction of photon exit, the corresponding theoretical extinction spectrum of the two-phase system mixed with first solid particles and second solid particles is obtained by calculation.Based on experimental extinction spectrum and theoretical extinction spectrum, the particle size and mixing number ratio of solid particles are obtained.

The present invention belongs to the technical field of hydrogen detection, and provides an LSPR hydrogen detection device based on a palladium nanoring array, which includes an optical detection unit, a sensing unit, and a data recording and processing unit. The optical detection unit is used to transmit the light emitted by the light source to the optical probe through an optical fiber, and then the optical probe irradiates the palladium nanoring array and the substrate in the sensing unit in parallel. When the palladium nanoring array undergoes a local surface plasmon resonance phenomenon, a strong resonance absorption peak will appear in the spectrum. The optical fiber in the data recording and processing unit will transmit the transmitted light and scattered light passing through the palladium nanoring array and the substrate to a spectrophotometer for measuring the scattered or extinction spectrum, and the computer terminal will perform data analysis and processing on the resonance absorption peak in the spectrum measured by the spectrophotometer to achieve hydrogen concentration detection. The present invention has the advantages of not generating sparks, not being affected by electromagnetic interference, being able to remotely read data, and not being affected by harsh environments.

The invention provides a method and system for detecting extinction, scattering and absorption characteristics of noble metal nanoparticles, and relates to the technical field of nano optical detection.The method comprises the steps that a sample with single particle distribution is prepared, the dark field scattering spectrum of a single particle is collected under dark field illumination, and the characteristic resonance wavelength of the single particle is determined through pretreatment and formant recognition; switching to bright field illumination, collecting a transmission spectrum at the same position, calculating an extinction spectrum and combining the extinction spectrum with scattering intensity to determine an absorption intensity initial value at a characteristic resonance wavelength; collecting a photo-thermal signal of the particle, and correcting the initial value of the absorption intensity by taking the amplitude of the photo-thermal signal as a correction factor to obtain a corrected absorption intensity value; according to the scattering intensity and the corrected absorption intensity value, the scattering efficiency and the absorption efficiency at the characteristic resonance wavelength are calculated, and then a scattering-absorption adaptation coefficient is determined; and comparing the adaptation coefficient with a dominant threshold, and judging that the nanoparticles are suitable for scattering-dominant, absorption-dominant or scattering-absorption synergistic applications.