65 results about "Sulfaclomide" patented technology

The invention relates to the technical field of industrial wastewater deep purification, and discloses an industrial wastewater deep purification system based on nano catalytic membrane separation, which comprises a pretreatment module, a catalytic degradation module, a membrane separation module, an intelligent control module and a regeneration maintenance module which are sequentially connected according to a treatment flow, the pretreatment module adjusts the water quality of inlet water to a range suitable for subsequent treatment through pH adjustment and suspended matter interception, that is, the pH is 2-11, and the turbidity is less than or equal to 50NTU; the catalytic degradation module is used for decomposing organic pollutants and mineralizing refractory substances under the excitation of ultraviolet / visible light by utilizing the photocatalytic characteristic of a nano catalytic membrane. The TiO2 / WO3 heterojunction nano catalytic membrane is adopted, so that deep oxidation of refractory pollutants such as phenol and sulfonamide antibiotics is realized, finally, the COD removal rate of 98.7% is achieved, and compared with a traditional photocatalytic process, the energy consumption is reduced by 54%.

The invention relates to a preparation method and application of a covalent organic framework material capable of adsorbing sulfonamide antibiotics. The method comprises the following steps: S1, respectively putting an amino-containing monomer and an aldehyde-containing monomer into a glass tube to obtain a mixture, then adding a solvent, performing ultrasonic uniform mixing, then adding an acetic acid solution for catalytic reaction, and performing uniform mixing to obtain a mixed solution; s2, freezing the mixed solution with liquid nitrogen, then circularly vacuumizing, sealing a glass tube, drying after treatment, cooling to room temperature, and filtering and washing to obtain a precipitate; and S3, carrying out Soxhlet extraction, repeatedly washing, and putting into a vacuum oven to obtain a product, namely the covalent organic framework material capable of adsorbing the sulfonamide antibiotics. According to the application, the adsorbent is applied to adsorption of sulfonamide antibiotics in water. The novel covalent organic framework material prepared by the invention is used for removing low-concentration sulfonamide antibiotics for the first time, and is considered as an excellent adsorption material capable of reducing the risk of water quality and guaranteeing the health of water quality.

The invention relates to the technical field of microbial treatment of antibiotic pollution, and discloses an antibiotic degrading bacterium with salt tolerance and capable of degrading sulfamethoxazole at low temperature and application, the strain degrades SMX in a wide temperature range of 10-40 DEG C, the degradation rate of 20mg / L SMX at 10-35 DEG C within 64 hours is greater than 70%, and the degradation rate of 20mg / L SMX at 20-30 DEG C reaches 100%; at the low temperature of 10 DEG C, low-concentration SMX is obviously degraded, and the SMX with the concentration of 5 mg / L can be completely degraded within 16 hours; the MJ2 can still effectively degrade SMX under the harsh conditions that the temperature is low and SMX serves as the unique carbon and nitrogen source, the degradation rate reaches 100% after 66h at the concentration of 5 mg / L, and it is proved that the MJ2 has the unique oligotrophic adaptability. Salinity tests show that the degradation rate of MJ2 to 20 mg / L SMX within 48 hours under the 0.1-2% NaCl concentration is 100%, the degradation rate is still kept at 50% even under the stress of 3% high salt, and remarkable salt tolerance is also shown. In conclusion, the strain MJ2 integrates wide temperature range adaptability, low-temperature high efficiency, oligotrophic tolerance and high salt stability, and has great application value in sulfonamide antibiotic pollution remediation in a complex environment.

The application discloses a kind of nano magnetic flocculants and its preparation method and application, belong to drinking water processing technical field, including the following steps: step S1, modified ferroferric oxide nanosphere is ultrasonically dispersed in ammonia alcohol solution, while stirring, slowly drop adding tetraethyl orthosilicate, continue stirring after drop, after centrifugal separation, wash, obtain silica coated ferroferric oxide nanoparticles;Step S2, phenylalanine modified chitosan is added into glacial acetic acid solution, after completely swelling and dissolving, add silica coated ferroferric oxide nanoparticles and ultrasonic treatment, under low pressure ultraviolet lamp, then with anhydrous ethanol wash purification, vacuum drying to constant weight, obtain nano magnetic flocculants;The method of the application is simple and easy to operate, the nano magnetic flocculants prepared can be quickly adsorbed to the surface of sulfonamide antibiotics, produce flocculation and can be magnetically separated, very suitable for trace sulfonamide antibiotics in drinking water source efficient removal.

The invention belongs to the technical field of biochar preparation, water treatment and new materials, and discloses a composite material for sulfonamide antibiotic treatment, a preparation method and application, and the preparation method comprises the following steps: preparing sludge biochar SBC; mnO2 coated OSBC is prepared; aminated PCA is prepared; pCA-MnO2 (at) OSBC is prepared; the preparation method comprises the following steps: cutting absorbent cotton, ultrasonically cleaning with deionized water, drying, dispersing PCA-MnO2 coated OSBC into a polyvinyl alcohol PVA solution, dipping the absorbent cotton, dropwise adding glutaraldehyde for crosslinking, curing, dipping into a PCA-MnO2 coated OSBC suspension, and carrying out freeze-drying heat treatment. The composite material disclosed by the invention has relatively stable physical properties and chemical properties, can be efficiently separated from an aqueous solution and recycled after being degraded, and can achieve a relatively good degradation effect in various typical real water bodies.

The present invention belongs to the field of biomedicine technology, and specifically relates to a combination drug combination and application for inhibiting the proliferation of NPM1 mutant leukemia cells. The combination drug combination includes RAS selective lethal molecule 3 and sulfonamide antibiotics; and anti-tumor small molecule drugs. The sulfonamide antibiotics include sulfasalazine; the anti-tumor small molecule drugs are selected from one or more of cytarabine, daunorubicin and venetoclax. The present invention also provides the application of the pharmaceutical composition in the combination drug combination in the preparation of an NPM1 mutant leukemia ferroptosis effect evaluation reagent.

The application discloses a method for efficiently removing sulfonamide antibiotics by flocculent sludge domestication, and belongs to the technical field of sewage treatment. The method greatly improves the removal rate of sulfonamide antibiotics by adjusting the culture conditions of activated sludge in a traditional activated sludge system. The method can effectively remove antibiotics, has the characteristics of simple operation, low treatment cost and large-scale operation, and the removal of pollutants is mainly realized by sludge adsorption and microbial degradation. The important functional bacteria, nitrifying bacteria, in the activated sludge treatment process can improve the removal efficiency of antibiotics including antibiotic drugs through co-metabolism while completing nitrification, so that the functional bacteria can be enriched by inoculating activated sludge and domesticating the sludge into flocculent form, and the functional bacteria are used to efficiently remove sulfonamide antibiotics.

The present invention provides a method for the efficient mineralization of organic pollutants by series electrochemical method, which belongs to the field of water treatment technology. 1 O2+SO4 ·– ‑TRS system, the system adopts a two-electrode DC power supply, and sequentially includes a singlet oxygen degradation system and a sulfate radical degradation system; the singlet oxygen degradation system uses a Fe / CNT electrode as a cathode and a Ti4O7 as an anode; the sulfate radical degradation system uses a Fe / CA electrode as a cathode and a Ti4O7 as an anode. 1 O2) and sulfate radicals (SO4 ·‑ ) 1 O2+SO4 ·– The TRS system can achieve 90-100% mineralization of sulfonamide antibiotics (SAs) within 30 minutes, which is much higher than that of the single 1 O2 / HO · / SO4 ·– ‑AOP system.

The invention discloses a copper-zinc double-active metal site adsorbent with atom dispersion, a preparation method thereof and application of the copper-zinc double-active metal site adsorbent in adsorption of sulfonamide antibiotics. The preparation method comprises the following steps: carrying out solvothermal reaction on a methanol solution containing copper acetylacetonate, zinc acetate and 2-methylimidazole in a mass ratio of (0.12-0.24): (0.8-0.9): (1.3-1.4), taking a solid after the reaction is ended, washing, drying, and calcining in an inert atmosphere to obtain the copper-zinc double-active metal site adsorbent with atom dispersion. The adsorbent has the following prominent advantages that copper and zinc are anchored to a nitrogen-rich carbon skeleton in a monatomic form, copper and copper diatoms exist on the surface, and the utilization rate is high; the synergistic effect of the nitrogen-doped carbon matrix and active sites of copper and zinc endows the material with an adjustable electronic structure; the porous carbon structure provides a stable anchoring point for metal atoms, metal dissolution is effectively inhibited, and secondary pollution is avoided.

The invention discloses a method for preparing a cobalt single-atom nano-island catalyst and an application for degrading sulfonamide organic pollutants, and relates to the technical field of antibiotic degradation. The present invention dissolves zinc acetate and cobalt acetate in a solvent, adds alkali to the system, obtains a precursor solution, and then hydrothermally reacts the precursor solution at 150-160°C, and obtains a cobalt single-atom nano-island catalyst after drying. The present invention prepares a nano-island-shaped single-atom dispersed catalyst in which cobalt single atoms are confined and dispersed on zinc oxide, and the unique structure can effectively avoid agglomeration and deactivation of cobalt single atoms during the reaction. The cobalt single-atom nano-island catalyst of the present invention can efficiently degrade various sulfonamide organic pollutants, and has a strong ability to resist interference from inorganic ions and organic matter, and has a large application potential for actual wastewater treatment.

The invention discloses a preparation method of a sulfonamide antibiotic efficient adsorbent, which comprises the following steps: adding tetrabenzyl phosphate, a cross-linking agent, an auxiliary agent and a catalyst into a solvent according to a certain proportion, and carrying out Friedel-Crafts alkylation reaction at a certain temperature to obtain a product; and purifying the product to obtain the porous adsorbent. The prepared efficient adsorbent for the sulfonamide antibiotics has a relatively high specific surface area and a hierarchical pore structure, contains rich oxygen and phosphorus elements, has relatively high adsorption capacity on various sulfonamide antibiotics, is relatively high in adsorption rate, and can be regenerated and recycled through regeneration treatment. The efficient adsorbent for the sulfonamide antibiotics, provided by the invention, is simple in preparation method and relatively low in cost, can be used for quickly and efficiently treating sewage containing the sulfonamide antibiotics, and has wide popularization and application prospects.

The invention discloses a method for synthesizing a single-atom cobalt catalyst by pyrolysis of a ligand-assisted supramolecular strategy and the resulting catalyst and application, and belongs to the field of water pollution control technology. The method provided by the present invention comprises the following steps: cobalt phthalocyanine and trimesic acid are mixed in water to obtain a cobalt phthalocyanine trimesic acid complex solution; then a dicyandiamide aqueous solution is added, and after stirring, an N-allylthiourea aqueous solution is added, and after the stirring reaction, the solid product obtained is washed and dried, and then pyrolysis is performed at high temperature, and the pyrolysis product is acid-leached and washed, and a single-atom cobalt catalyst is obtained after drying. The method of the present invention can obtain a single-atom cobalt catalyst with a high cobalt loading, and at the same time, it can achieve efficient degradation of sulfonamide antibiotics in sewage, and the removal rate of sulfonamide antibiotics can be made to reach more than 90% within 2 minutes, and the antibiotic removal rate within 5 minutes reaches more than 98%, and after multiple recycling, very high catalytic efficiency can still be maintained.

The invention discloses a method for detecting sulfonamides residues in milk, which comprises the following steps: firstly, mixing to-be-detected milk containing sulfonamides with a deproteinization reagent, performing deproteinization treatment on the to-be-detected milk, then removing solids in the formed deproteinized mixture, and adjusting the obtained clear liquid to be acidic, obtaining a pretreated sample; then uniformly mixing the pretreated sample and a color developing agent to form a mixed sample; then, applying a medium-frequency oscillation electric field to the mixed sample, enabling the mixed sample to fully react to form a to-be-detected sample, continuously applying the medium-frequency oscillation electric field, and measuring the light absorption value of the to-be-detected sample at the ultraviolet wavelength; and finally, calculating the content of the sulfonamides in the milk to be detected according to the measured light absorption value and a pre-established standard curve relational expression. Compared with the prior art, the detection method is high in precision, sensitivity and accuracy and short in detection time.

The invention relates to a method for analyzing pollutants in hospital wastewater based on liquid chromatography-high resolution mass spectrometry. The method comprises the following steps: S1, enriching pollutants in hospital wastewater through solid-phase extraction of four specific solid-phase extraction columns, and then analyzing and detecting a liquid to be detected through a specific chromatographic column, a specific liquid chromatography and a high-resolution mass spectrometry which are connected in series; the identification of various pollutants (medicines and metabolites thereof) in the hospital wastewater is realized, so that a data basis is provided for subsequent fingerprint analysis. Specifically, the analysis method provided by the invention can identify 34 kinds of substances, including sulfonamide antibiotics, macrolide antibiotics, cephalosporin antibiotics, quinolone antibiotics, beta-lactam antibiotics, aminoglycoside antibiotics and carbamazepine and metabolites thereof.

The purpose of the present invention is to provide a compound that has an excellent effect of inducing BRD4 protein degradation and is useful as a cancer therapeutic agent, or a pharmaceutically acceptable salt thereof. A compound represented by formula (I) or a pharmaceutically acceptable salt thereof. [In the formula, each symbol is as defined in the description.]

The invention discloses preparation of a copper-based biomass composite catalyst and activation of PMS to degrade sulfonamide antibiotics in a water body, and belongs to the field of environmental engineering water treatment. The glutaraldehyde is used as a cross-linking agent, and the material and a chelate formed by metal ions form a fixed space structure, so that the problem of dissolution of the metal ions in the catalysis process is solved. Biomass gelatin and chitosan are used as raw materials to firstly prepare biomass composite microspheres, then the copper-based biomass composite catalyst is obtained through impregnation and crosslinking, and the copper-based biomass composite catalyst is used for activating PMS to degrade sulfonamide antibiotics in a water body. According to the present invention, the reaction conditions of the catalyst are simple, the green degradable material is used, the prepared catalyst is easy to store, the dissolution problem of copper ions during the catalysis process is effectively solved by introducing the cross-linking agent, and the sulfonamide antibiotics show the excellent removal performance.

The invention discloses a sulfanilamide drug-resistant gene standard substance as well as a preparation method and application thereof. The preparation method comprises the following steps: (1) gene synthesis and clone construction; (2) preparing plasmid DNA (deoxyribonucleic acid); (3) DNA standard substance identification, subpackaging and storage; and (4) determining the value of the standard substance. According to the method, two valuing methods with different principles are adopted, a multi-step standard substance candidate purification method is developed by researching factors influencing the consistency of quantitative results between the two valuing methods, and impurities influencing the valuing results are removed. By optimizing preparation and valuing of the standard substance, equivalence and consistency of two valuing methods with different principles are achieved, and the problem that valuing can only be carried out through cooperation of multiple laboratories is solved.

The invention provides an incubation-free composite SERS (Surface Enhanced Raman Scattering) substrate as well as a preparation method and application thereof. The preparation method comprises the following steps: providing Ag nanoparticles; providing a nano carbon material, and loading the Ag nanoparticles on the surface of the nano carbon material to form an SERS solution system with a composite nano structure; loading a cationic polyelectrolyte structure on the surface of the nanofiber membrane to obtain a composite fiber membrane; the SERS solution system is dripped onto the composite fiber membrane, and the incubation-free composite SERS substrate is obtained. The detection efficiency and sensitivity of the sulfonamide antibiotics can be remarkably improved, and the application prospect is wide.

The present invention belongs to the technical field of antibiotic degradation treatment, and specifically relates to an anaerobic microorganism combination with sulfonamide antibiotic degradation function and its application. The present invention provides two anaerobic microorganisms for sulfonamide antibiotic treatment, namely ParaclostridiumbifermentansJ2 and Clostridium sp.J2. These two anaerobic microorganisms can degrade sulfonamide antibiotics, and the removal effect of sulfonamide antibiotics can be enhanced by combining the two. In addition, after ParaclostridiumbifermentansJ2 and / or Clostridium sp.J2 are made into microbial immobilized bacterial balls with sodium alginate and biochar, they can still be quickly started in a short time and sulfonamide antibiotics can be removed efficiently, which provides a new way for the degradation of sulfonamide antibiotics and the treatment of sulfonamide antibiotic pharmaceutical wastewater.

The invention provides pH response type hydrogel as well as a preparation method and application thereof. The pH-responsive hydrogel is prepared from the following raw materials: a hydrophobic monomer, a sensitive monomer, a cross-linking agent, an initiator and an organic solvent, the hydrophobic monomer comprises at least one of methyl acrylate, ethyl acrylate, benzyl acrylate and 2-phenoxyethyl acrylate, and the sensitive monomer comprises at least one of a cross-linking agent, an initiator and an organic solvent. The sensitive monomer comprises a sulfanilamide monomer containing an acryloyl group or a methacryloyl group. According to the pH response type hydrogel disclosed by the invention, the drug release rate difference is obvious under different pH values. Under a low pH value, a slow drug release speed can be maintained, and under a high pH value, rapid drug release can be realized. And the release amount at high pH for 24 hours can reach 150-600% of the release amount at low pH for the same time. The invention further provides a preparation method and application of the pH response type hydrogel.

The invention relates to application of naphthoquine or pharmaceutically acceptable salt in preparation of drugs for resisting drug-resistant bacteria and drugs for treating pneumonia, and the naphthoquine is an antibacterial drug for inhibiting reproduction of the drug-resistant bacteria or killing the drug-resistant bacteria. The technical problems that in the prior art, acinetobacter baumannii LAC-4 mainly generates drug resistance to sulfonamides, and the scheme for treating acinetobacter baumannii LAC-4 infection is very limited clinically are solved through the proposal of phenoquine or pharmaceutically acceptable salt.

The invention discloses a trimethoprim / polyacrylic resin solid dispersant as well as a preparation method and application thereof, and belongs to the technical field of veterinary drug preparations. The trimethoprim / polyacrylic resin solid dispersant comprises the following raw materials: trimethoprim and polyacrylic resin, wherein the mass ratio of the trimethoprim to the polyacrylic resin is 0.02 to 0.3; and dissolving the raw materials with an organic solvent, and dialyzing or evaporating to remove the solvent to prepare the trimethoprim / polyacrylic resin solid dispersant. The prepared solid dispersing agent is high in drug loading rate and good in stability, and the formed solid dispersing agent obviously improves the glass transition temperature of trimethoprim. Besides, the preparation method is convenient to operate, simple and easy to implement, and the obtained solid dispersing agent can be compounded with the sulfonamides antibacterial drugs to serve as a synergist of the sulfonamides antibacterial drugs, so that the antibacterial effect of the sulfonamides antibacterial drugs is improved.

The present invention discloses a method for enriching and separating sulfonamide antibiotics in drinking water or milk, comprising the following steps: sample processing: adding trichloroacetic acid solution to the sample, vortexing and then ultrasonically centrifuging, and collecting the supernatant; magnetic deep eutectic solvent synthesis: stirring choline chloride, phenol and ferric chloride at room temperature to form a magnetic deep eutectic solvent; magnetic deep eutectic solvent / salt two-phase aqueous system: adding the formed magnetic deep eutectic solvent to the supernatant, vortexing and oscillating, adding salt, vortexing and oscillating, to form a magnetic deep eutectic solvent / salt two-phase aqueous system; extraction: placing a magnet at the bottom of the solution to attract magnetic droplets, moving the magnet upward to achieve phase separation of the two-phase aqueous system, accurately measuring the volumes of the upper and lower phases, and using a high performance liquid chromatograph to determine the concentration of sulfonamide antibiotics in the lower inorganic salt phase. This method can efficiently separate and enrich sulfonamide antibiotics, and the selected solvent is non-toxic and pollution-free, providing a new idea for the separation and enrichment of trace sulfonamide antibiotics.

This invention discloses a method for the efficient degradation and deep mineralization of sulfonamide antibiotics in wastewater, relating to the field of wastewater treatment technology. The method includes the following steps: preparing a phosphate buffer solution and adding Na6TPP working solution, adding SAs working solution, adjusting the pH, adding iron filings and carbon fibers, injecting air, and reacting for 3 hours to obtain a reaction solution; taking sterilized nutrient solution containing SAs-containing anaerobic activated sludge; adding activated sludge to the sterile nutrient solution to prepare the reaction solution, sealing and shaking for incubation; allowing it to stand for seven days after degradation, repeating the preparation of sterile nutrient solution, continuing enrichment, and obtaining SAs-containing activated sludge; after removing iron from the reaction solution using anion exchange resin, adding trace elements and vitamins to prepare an anaerobic activated sludge nutrient solution; inoculating the acclimated SAs-containing activated sludge into the nutrient solution, shaking for incubation, and continuing to degrade the remaining organic matter after pre-oxidation. This invention deeply mineralizes SAs, thereby increasing the degradation rate of sulfonamide antibiotics and total organic carbon.

The invention relates to the technical field of food safety detection, and particularly provides an analysis method and system for detecting various antibiotic residues in edible parts of vegetables. According to the method, aiming at the problem that various antibiotics in vegetables are difficult to efficiently and accurately detect at the same time in the prior art, synchronous and efficient extraction and purification of sulfonamides, quinolones and tetracyclines antibiotics are realized by optimizing a sample pretreatment process; according to the method, specific ultra-high performance liquid chromatography-tandem high-resolution mass spectrometry analysis conditions are combined, intelligent comparison is performed by utilizing a pre-constructed standard compound database, and rapid screening and accurate quantification of various target antibiotics in the complex vegetable matrix are completed. The invention provides a set of complete solution, has the advantages of universal and efficient pretreatment, high detection flux, good accuracy and the like, and provides a reliable technical means for daily monitoring and risk assessment of antibiotic residues in vegetables.

The present invention belongs to the technical fields of biochar preparation, water treatment, and new materials, and discloses a composite material, a preparation method, and an application for the treatment of sulfonamide antibiotics, which include the following steps: preparing sludge biochar SBC; preparing MnO2@OSBC; preparing aminated PCA; preparing PCA-MnO2@OSBC; cutting degreased cotton, ultrasonically cleaning it with deionized water, drying it, dispersing PCA-MnO2@OSBC in a polyvinyl alcohol PVA solution, impregnating the degreased cotton, dropping glutaraldehyde for crosslinking, curing, immersing it in a PCA-MnO2@OSBC suspension, and freeze-drying and heat-treating. The composite material of the present invention has relatively stable physical and chemical properties, can achieve efficient separation and recycling from the aqueous solution after degradation, and can achieve good degradation effects in a variety of typical real water bodies.

The invention discloses an adsorption-oxidation difunctional boron-doped porous biochar material and a preparation method and application thereof, the preparation method comprises the following steps: mixing alfalfa, sodium bicarbonate, boric acid and water, evaporating and pyrolyzing to obtain the boron-doped porous biochar material. The adsorption-oxidation dual-function boron-doped porous biochar material has the advantages of large specific surface area, developed multi-stage pore structure, rich oxygen-containing functional groups, good surface affinity, high-reaction-activity boron-doped species BC3 and the like, so that the adsorption performance and the catalytic performance are excellent; when being applied to a persulfate advanced oxidation technology, the catalyst can realize efficient removal of sulfonamide antibiotics mediated by a non-free radical way, has the advantages of strong adsorption capacity, high catalytic activity, good recycling property and the like, and shows good practical application potential.

The invention discloses a pseudointermediate Brucella strain for degrading sulfonamide antibiotics, the pseudointermediate Brucella strain is preserved in the Guangdong Microbial Culture Collection Center, and the preservation number of the pseudointermediate Brucella strain is GDMCC No: 63617. The pseudointermediate Brucella strain can be used for degrading the sulfonamide antibiotics, and the pseudointermediate Brucella strain is preserved in the Guangdong Microbial Culture Collection Center. The invention also provides application of the Brucella pseudointermedius strain for degrading the sulfonamide antibiotics, and the strain has very strong degradation capability on the sulfonamide antibiotics in livestock and poultry wastes (especially livestock and poultry manure or compost thereof), and can simultaneously have very strong degradation capability on various sulfonamide antibiotics in the livestock and poultry manure or compost thereof; and the microbial agent has good compatibility with native microbial flora in livestock and poultry wastes (especially livestock and poultry manure or compost thereof), and has strong adaptability.

The application discloses a method for degrading sulfonamide antibiotics in wastewater by using goethite and Fe(II) salt. The specific steps include: dissolving Fe(II) salt, adding goethite, and fully adsorbing Fe(II) to goethite to prepare a goethite and Fe(II) mixture; anaerobically pretreating wastewater containing sulfonamide antibiotics, adding the goethite and Fe(II) mixture to a sulfonamide antibiotic wastewater treatment unit, carrying out anaerobic reaction, separating and discharging water, and starting the next cycle of treatment; on-line monitoring the oxidation-reduction potential of each reaction stage, controlling the start and end of the reaction by the oxidation-reduction potential, and supplementing Fe(II) again to restore the degradation performance when the degradation efficiency of the sulfonamide antibiotic decreases and is controlled by the oxidation-reduction potential. The method is mild, the materials are cheap and easy to obtain, and the method is environment-friendly, and the sulfonamide antibiotic can be directionally degraded; Fe(II) can be recycled, and the purpose of efficiently treating sulfonamide antibiotic wastewater is achieved.

The invention discloses a CuMgFe LDH catalytic membrane and application thereof in the degradation of sulfonamide antibiotics. The invention adopts a method combining in-situ self-assembly and vacuum filtration to prepare the CuMgFe LDH catalytic membrane. The CuMgFe LDH is evenly and tightly anchored in the membrane pores, exposing more active sites, thereby improving the stability and anti-pollution property of the catalytic membrane.