Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

44 results about "Transplantation surgery" patented technology

Dynamic coprophilous fungus transplantation donor and acceptor matching method, device, equipment and medium

The embodiment of the invention discloses a coprophilous fungus transplantation donor and acceptor dynamic matching method, device and equipment and a medium, and the method comprises the steps: responding to a donor and acceptor matching request, and obtaining the monitoring data of a to-be-matched acceptor after coprophilous fungus transplantation at the current preset sampling time; wherein the monitoring data after coprophilous fungus transplantation is determined on the basis of the coprophilous fungus transplantation operation of a to-be-matched receptor completed by the coprophilous fungus flora of any target donor, and the target donor is determined by performing adaptability matching on the gene feature information, the immune feature information and the clinical feature information of the to-be-matched receptor and a plurality of to-be-selected donors; and inputting monitoring data after coprophilous fungi transplantation into the transplantation strategy control model, outputting at least one of a donor switching strategy and a dose adjustment strategy for adjusting a to-be-matched receptor in a next time period, realizing comprehensive compatibility evaluation through multi-modal data integration, continuously optimizing a treatment scheme by means of a dynamic feedback mechanism, and improving the compatibility of the to-be-matched receptor. And the accuracy and adaptability of coprophilous fungus transplantation treatment are remarkably improved.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

Hair transplantation surgery with graft-on-demand processing of follicular units

ActiveUS12433739B2Skin implantsDiagnosticsRobotic armGraft transplant
The harvesting of hair for a hair transplant procedure with immediate placement of the hair grafts to the balding area, employs a hollow drill connected to a suction with an imaging system (containing one or more cameras) which permits alignment of the center of the cutting edge of the needle on or slightly offset from the axis of the hair within the follicular unit to be removed. This harvesting tool may be robotically controlled. As each follicular unit may have more than one hair, the surgeon controls the number of hairs in each graft he wishes to remove, excising the graft one at a time. A special FUE tool is used that excises the entire follicular unit with minimal residual attachments. The tool utilizes vacuum to facilitate complete excision. The graft that is excised is sucked though tubing and almost instantaneously delivered to an implanter held by the surgeon (Duplex Implanter) or by a robot. This graft on Demand system is controlled by the surgeon through a series of commands to the handpiece of the implanter for one, two, three or more hair grafts. The excision needle (punch) is placed to remove a hair graft with the chosen number of hairs, taken from an area which has been previously mapped out. When properly aligned, a follicular unit is removed without damaging critical anatomical portions of the follicles and it is delivered to the implanter at the command of the surgeon. In one embodiment, a movable x / y / z stabilizing gantry is employed to position the hollow needle in each instance which can be manually controlled by the surgeon, or robotically controlled with one or more robots. In another embodiment, a computer maps out the location of every graft within the surgical field of view, in part or in whole, and selects those follicles, minimizing the spacing left remaining after each excision while obtaining the number of grafts targeted by the surgeon. In still another embodiment, one or more robotic arms, controlled automatically by a controller or manually by a surgeon, operate graft excision instruments to facilitate speed and accuracy of the excision process.
Owner:ENGRAFT TECH INC

Corneal graft implanter for corneal transplantation

ActiveCN223263091UEye implantsEye surgeryInjection portCorneal Endothelial Cell Loss
The utility model relates to the technical field of corneal transplantation surgical instruments, in particular to a corneal graft implanter for corneal transplantation surgery, which comprises an implanter element, a connecting hose, a bottle cap, a bottle body and an injector, the bottle cap comprises a cap body and a push-pull plunger device, the push-pull plunger device comprises a plunger rod, a plunger and a plunger cylinder, and the plunger rod is connected with the connecting hose. One end of the plunger rod is fixedly connected with the cover body, the other end of the plunger rod penetrates through the top of the plunger cylinder in an airtight mode and is fixedly connected with a plunger matched with the plunger cylinder in the plunger cylinder, and a connecting pipe is arranged at the bottom of the plunger cylinder. And the connecting hose is used for connecting the top of the implanter element with the connecting pipe or the injection port of the injector. The implanter is used for pre-loading a donor cornea graft; the donor corneal graft is stored and transported to an operation position of a patient in a sterile mode and can be directly taken and used, and the donor corneal endothelial cell loss is avoided to the greatest extent in the receiving and implanting process of the donor corneal graft; meanwhile, a small-incision cornea transplantation operation is carried out through the implanter, and convenient transplantation is provided for ophthalmologists.
Owner:QINGDAO CAIHUI BIOTECHNOLOGY CO LTD

Retractor device for kidney transplantation surgery

The application provides a retractor for kidney transplantation surgery and relates to the technical field of medical auxiliary devices.The retractor comprises a retractor assembly and control pliers for controlling the opening and closing of the retractor assembly.The control pliers comprise two plier heads, and the retractor assembly comprises two retractor parts connected to the corresponding plier heads respectively.Two sets of the retractor assembly and the control pliers are symmetrically arranged, and a first driving device is arranged between the two sets of control pliers to maintain and / or adjust the distance between the two control pliers.A second driving device is arranged inside the control pliers to adjust the opening and closing angle of the control pliers.Both the first driving device and the second driving device are hydraulic telescopic elements.The application greatly improves the efficiency of the surgery and shortens the surgery time.In the process of the surgery, the surgery posture of the patient and the related equipment can be greatly adjusted without the need for secondary traction positioning, and the normal performance of the surgery is not affected by the great change of the surgery window.
Owner:GUANGDONG NO 2 PROVINCIAL PEOPLES HOSPITAL

Composition for soft tissue increment and preparation method thereof

The invention relates to the technical field of medical materials, in particular to a composition for soft tissue increment and a preparation method thereof, and the composition for soft tissue increment comprises a plasma matrix compressed material and a microvesicle concentrated solution. The composition for soft tissue increment provided by the invention comprises a plasma matrix compressed material and a microvesicle concentrated solution, the plasma matrix compressed material is rich in effective substances such as platelets and immune cells, has a compact three-dimensional fibrous protein network structure, and can provide a required scaffold for soft tissue regeneration, so that the soft tissue regeneration effect is improved. The microvesicle concentrated solution contains a large number of effective biological components such as cell factors and signal molecules, regeneration of local soft tissue can be further regulated and controlled, the microvesicle concentrated solution and the microvesicle concentrated solution have a synergistic effect, the excellent soft tissue regeneration promoting capacity is achieved, a complete autologous source is achieved, connective tissue transplantation surgery is replaced, and the application prospect is wide. The excellent performance is shown in the clinical application of soft tissue regeneration.
Owner:HUBEI PRIME SHIELD BIOTECHNOLOGY CO LTD

Transfer trolley for ovum-taking transplantation operation patient in reproductive center

The invention relates to the technical field of transfer trolleys, in particular to a transfer trolley for a reproductive center ovum taking transplantation operation patient, which comprises a shell and an inflation box, a placing plate is fixedly connected to the top of the shell, a rotating plate is hinged to the side wall of the placing plate, a sliding opening is formed in the placing plate, an inflation bag is in sliding fit with the sliding opening, and an inflation pipe fixedly circulates at the bottom of the inflation bag; a one-way valve fixedly circulates at the joint of the inflation bag and the inflation pipe, the inflation pipe penetrates through the sliding opening and is in sliding fit with the sliding opening, and the end, away from the inflation bag, of the inflation pipe fixedly communicates with the inflation box; a power assembly used for driving the rotating plate to rotate and driving the inflation bag to expand is arranged in the shell. A storage assembly used for storing medical supplies is arranged in the shell. A limiting assembly used for limiting the body position of a patient is further arranged. By lifting the head and below the knees of a patient, the patient can reach the best horizontal position posture, and the transplantation success rate and comfort are both improved.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Artificial meniscus (implant)

ActiveCN310047442SMeniscal injurySurgery
1. Name of the product in this design: Artificial Meniscus (Implantable). 2. Purpose of this design: This design is intended for use in meniscus transplantation surgery for patients with meniscus injuries. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.
Owner:SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV

Application of soluble epoxide hydrolase inhibitor in transplantation field

PendingCN120919124AOrganic active ingredientsImmunological disordersIMMUNE SUPPRESSANTSHydrolase inhibitor
The invention relates to an application of a soluble epoxide hydrolase inhibitor in the field of transplantation, the soluble epoxide hydrolase inhibitor is TPPU, and the soluble epoxide hydrolase inhibitor is applied in the fields of organ transplantation and tissue transplantation. The TPPU is used for relieving allogeneic mouse heart and skin transplantation immunological rejection, reducing immune cell infiltration in transplantation operation, and inhibiting CD4 + T cell proliferation, CXCR3 chemokine receptor positive and Th1 cell subset proportion. The TPPU inhibits proliferation of primary CD4 + T cells of normal mice and differentiation of Th1 cell subgroups. In organ transplantation and tissue transplantation, the invention provides a single soluble epoxide hydrolase inhibitor TPPU, which can relieve allogeneic mouse heart and skin transplantation immunological rejection, inhibit normal mouse primary CD4 + T cell proliferation and differentiation, and reduce toxic and side effects caused by the use of an immunosuppressant.
Owner:TIANJIN FIRST CENT HOSPITAL

Rapid prototyping and in vitro modeling of patient-specific coronary artery bypass grafts

ActiveUS12527895B2Image enhancementImage analysisCoronary arteriesIn Vitro Techniques
The present disclosure describes a system and a method for producing patient-specific small diameter vascular grafts (SDVG) for coronary artery bypass graft (CABG) surgery. In some embodiments, the method for producing SDVGs includes non-invasive quantification of patient-specific coronary and vascular physiology by applying computational fluid dynamics (CFD), rapid prototyping, and in vitro techniques to medical images and coupling the quantified patient-specific coronary and vascular physiology from the CFD to computational fluid-structure interactions and SDVG structural factors to design a patient-specific SDVG.
Owner:CORNELL UNIVERSITY

Embryo transplantation operating table for animals

The utility model discloses an animal embryo transplantation operating table, and belongs to the technical field of animal embryo transplantation. A groove is formed in the table body, a supporting plate is installed in the groove, four sliding grooves are formed in the top of the table body, the sliding grooves are T-shaped grooves, a fixing assembly comprises a sliding block and a fixing base, a fixing ring is arranged at the bottom of the sliding block, a clamping block is arranged at the bottom of the sliding block, the clamping block is a T-shaped block, the clamping block is clamped in the sliding grooves in a sliding mode, and the fixing base is fixedly connected to the top of the table body. The number of the fixing seats is four, blind holes are formed in the fixing seats, electric push rods are installed in the blind holes, and check blocks are fixedly connected to the moving ends of the electric push rods. According to the operating table, the fixing assembly is arranged, the animal to be operated is fixed on the operating table through the fixing assembly, the situation that the animal struggles in the operation process, and consequently operation is difficult is avoided, and the problem that the animal to be operated cannot be well fixed through the operating table is solved.
Owner:伊犁哈萨克自治州动物疾病控制与诊断中心

Isolated organ perfusion preservation device

The utility model provides an isolated organ perfusion preservation device which comprises an organ preservation assembly, a perfusion circulation assembly, a temperature adjusting assembly and a control assembly. The organ preservation assembly comprises a preservation tank body, an organ tray and a side plate supporting frame, the preservation tank body comprises an inner layer and an outer layer, the organ tray and the side plate supporting frame are both arranged in the inner layer of the preservation tank body, the side plate supporting frame is connected with the organ tray in the circumferential direction, and the organ tray is used for supporting an isolated organ; the perfusion circulation assembly comprises a perfusion liquid container, a gas separator and a filtering remover, the perfusion liquid container comprises an inner layer and an outer layer, and the inner layer of the perfusion liquid container is communicated with the inner layer of the storage tank body; the temperature adjusting assembly comprises a temperature adjusting liquid container, a temperature sensor and a temperature control unit, and the temperature adjusting liquid container, the outer layer of the storage tank body and the outer layer of the perfusate container are communicated with one another; the control assembly is connected with the temperature adjusting assembly and comprises a filtering unit and a PID adjusting unit. The utility model is beneficial to improving the organ preservation quality and improving the success rate of transplantation operation.
Owner:UNIV OF SHANGHAI FOR SCI & TECH +3

Tissue phase homogenizing agent as well as preparation method and application thereof

PendingCN120919401ATissue regenerationProsthesisSwelling ratioPolyvinyl alcohol
The invention provides a tissue phase homogenizing agent and a preparation method and application thereof, and belongs to the technical field of biological tissue engineering, the homogenizing agent is composed of hydrophilic matrixes (glucose, polyglycerol, poloxamer F127 and polyvinyl alcohol), functional additives (mannose, N-acetylcysteine, sodium hyaluronate and polyethylene glycol) and ultrapure water, and the pH value is 7.0 + / -0.2. Hydrophilic groups and water molecules form a hydrogen bond network, a continuous hydration layer is constructed on a phase interface, phase domain fusion, refractive index homogenization and molecular ordering are achieved, the problem of biological tissue phase homogenization is solved, tissue light transmittance can be improved, the swelling ratio can be stabilized, and the hydrogel has cell proliferation promoting activity and is suitable for tissue transplantation operation and bioengineering tissue preservation.
Owner:GUANGZHOU PUDAO LIANXIN BIOTECH CO LTD

Hair transplant instrument and method

An instrument for use in hair transplant surgery has a hollow handle (1,2, Fig 2) containing an electronics assembly having a microswitch 9 coupled to an axially displaceable chuck assembly 15, 22. Th
Owner:NISHAL N PATEL

Intelligent surgical planning method and system for autologous tooth transplantation

The present invention provides an intelligent surgical planning method and system for autologous tooth transplantation, relating to the field of image processing technology. The method comprises: obtaining a CBCT image of a tooth to be operated on; segmenting each individual tooth in the CBCT image using a 3D UX‑Net network; segmenting the upper and lower jaws in the CBCT image using a SegResNet network; determining various feasible transplantation surgical planning schemes for transplanting an alternative donor tooth to a recipient tooth using principal component analysis based on the segmentation results of the individual teeth and the jaw; and determining the optimal transplantation surgical planning scheme based on the crown overlap rate, root overlap rate, and amount of bone grinding between the recipient and donor teeth in various transplantation surgical planning schemes. The method achieves precise segmentation of individual teeth and the upper and lower jaws; effectively controls the amount of bone grinding and optimizes the matching between the donor and donor teeth, thereby improving the surgical success rate and postoperative comfort.
Owner:UNIV OF SCI & TECH BEIJING

Therapies for neuromusculoskeletal injuries and limb transplantation

The present invention relates to the use of mesenchymal stem cells to reduce inflammation and immune responses for neuromuscular injuries and limb transplants. A particular preferred embodiment relates to use of mesenchymal stem cells that are modified to express interleukin-10 in limb transplantation surgery. In particular embodiments, the present invention also provides a method of improving nerve and muscle regeneration and functional outcome for limb transplantation in a mammalian limb transplant recipient by administering to the limb transplant recipient a therapeutic amount of mesenchymal stem cells.
Owner:THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE DIRECTOR OF THE DEFENSE HEALTH AGENCY

Retraction device for kidney transplantation operation

The invention provides a retraction device for kidney transplantation, and relates to the technical field of medical auxiliary instruments, the retraction device comprises a retraction assembly and a control clamp for controlling the retraction assembly to open and close, the control clamp comprises two clamp heads, and the retraction assembly comprises two retraction parts connected with the corresponding clamp heads respectively; two groups of retracting assemblies and two groups of control forceps are symmetrically arranged, a first driving device is arranged between the two groups of control forceps and is used for maintaining and / or adjusting the distance between the two groups of control forceps, and a second driving device is arranged in the control forceps and is used for adjusting the opening and closing angles of the control forceps; the first driving device and the second driving device are hydraulic telescopic elements. According to the invention, the operation efficiency is greatly improved, and the operation time is shortened; in addition, in the operation process, the operation posture of the patient and related equipment can be greatly adjusted, secondary traction positioning is not needed, and meanwhile it is not needed to worry that the normal operation of the operation is affected by the great change of an operation window.
Owner:GUANGDONG NO 2 PROVINCIAL PEOPLES HOSPITAL

Manufacturing method of cavity preparation guide plate for autologous tooth transplantation operation

PendingCN121287339ADental implantsImpression capsDental transplantationDentistry
The invention discloses a manufacturing method of an autologous tooth transplantation operation cavity preparation guide plate. The manufacturing method comprises the following steps: S1, obtaining digital models of a transplanted tooth donor, a transplanted tooth and an alveolar bone, and respectively printing solid models; s2, preparing a hole in the alveolar bone entity model to simulate transplantation; s3, scanning the alveolar bone solid model after hole preparation to obtain an alveolar bone digital model after hole preparation; s4, registering and overlapping the two alveolar bone digital models before and after hole preparation to obtain the difference of the states of the alveolar bone before and after hole preparation, and modeling according to the amount of the ground bone during hole preparation to obtain a bone grinding amount digital model; s5, designing a bone grinding guide plate model through the prismoid and the cone; s6, simulating placement of the bone grinding guide plate model, and trimming the position, shielded by the alveolar fossa, of the bone grinding guide plate model; and S7, designing side wings and combining the side wings with the bone grinding guide plate model. Compared with the prior art, the method has the advantages that the fitting rate of the transplanted tooth donor and the alveolar socket and the success rate of one-time implantation and in-place of the transplanted tooth donor are improved.
Owner:THE THIRD HOSPITAL OF CHANGSHA

Intelligent auxiliary method for autogenous bone transplantation

PendingCN120814904ABone implantComputerised tomographsCutting force modelAutogenous bone graft procedure
The invention discloses an intelligent auxiliary method for autologous bone transplantation, which comprises the following steps: constructing a three-dimensional jaw bone model, a three-dimensional tooth model and a three-dimensional defect area model based on CBCT (cone beam computed tomography) image data of a target object; according to the three-dimensional defect area model, obtaining defect area three-dimensional form data, inputting the defect area three-dimensional form data into the trained bone increment prediction model, and outputting to-be-supplemented autologous bone block design parameters; according to the design parameters of the to-be-supplemented bone block, in combination with the three-dimensional tooth model, determining a bone taking position of the to-be-supplemented bone block in the three-dimensional jaw bone model, and automatically marking the bone taking position so as to plan a bone block cutting path; according to the bone block cutting path, a predicted cutting force is obtained by combining a cutting force model; planning the motion track of the mechanical arm according to the predicted cutting force to realize auxiliary cutting of the autogenous bone block; in the cutting process, the actual cutting force is monitored in real time, and the movement track of the mechanical arm is dynamically adjusted according to the actual cutting force. According to the method, the preoperative planning is optimized, the operation precision in the operation is improved, and the operation risk is reduced.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

A method and system for augmented reality navigation of lamellar keratoplasty surgery based on a joint learning strategy

ActiveCN117671205BLamellar keratoplastyEngineering
The application relates to a kind of based on the method and system of joint learning strategy's lamellar keratoplasty surgery augmented reality navigation, comprising: based on the acquisition surgery image of camera unit and conversion into single frame image, and carry out normalization processing to construct neural network model input;Based on frame-by-frame image, utilize joint learning deep neural network model to obtain surgery instrument, corneal region segmentation result and corresponding completion optical flow result;The image and corresponding completion optical flow result of current frame and forward adjacent frame are combined, and the completion information of current frame is comprehensively calculated, and the area blocked by surgery instrument is recovered by completion calculation;Utilize corneal region segmentation result to realize the augmented reality navigation result of superimposed surgery suture line and point position on the completion surgery image by ellipse fitting and suture point calculation process.The application can realize the construction of augmented reality navigation information for lamellar keratoplasty surgery, guide surgery related operation, improve surgery efficiency.
Owner:BEIHANG UNIV

Autologous tooth transplantation surgery tooth in place and adhesive integrated guide plate and manufacturing method

ActiveCN115444598BDental implantsDental transplantationTooth position
The application discloses a self-tooth transplantation surgery tooth positioning and bonding integrated guide plate and a manufacturing method. The transplantation guide plate is used to realize preoperative design of a bonding process. Through simulation of a form of a tooth transplantation surgery tooth positioning guide plate, relative positions of the tooth transplantation guide plate and the tooth transplantation guide plate and adjacent teeth are fixed, so that the tooth transplantation surgery preoperative design implantation position is accurately reproduced in surgery.
Owner:周丽斌

An extrusion printing process parameter design method based on rheological properties of biological materials

The application discloses a kind of based on the rheological property of biological material extrusion printing process parameter design method, it relates to additive technology field.The present application solves the problem of low filament diameter precision in the existing biological material 3D printing due to the neglect of material rheological property, and the printing parameters obtained are not ideal, and further lead to low precision.The application builds a 3D printing device that can control key parameters separately, realizes 3D printing of target material under different parameters and records printing precision, builds a printing precision prediction model based on experimental data and optimizes printing parameters, and completes filament printing with high diameter precision.Through rheological test, analyze rheological data, determine the optimal temperature and extrusion speed;Through the 3D printing device that can control temperature and extrusion speed separately, explore the relationship between printing precision and process parameters in the printing process.The application is used for the additive printing of tissue or organ for transplantation surgery.
Owner:HARBIN INST OF TECH

Organ maintenance liquid for repairing liver function as well as preparation method and application of organ maintenance liquid

The invention discloses an organ maintenance liquid for repairing liver functions as well as a preparation method and application of the organ maintenance liquid. The feed additive comprises the following components: an oxygen-carrying component, succinyl gelatin, sodium chloride, sodium hydroxide, sodium bicarbonate, calcium gluconate, magnesium sulfate, chromium chloride, copper chloride, ferric chloride, manganese chloride, sodium molybdate, sodium selenite, zinc chloride, potassium iodide, sodium fluoride, isoleucine, leucine, lysine acetate, methionine, phenylalanine, threonine, tryptophan, serine, valine and histidine. The injection is prepared from arginine, alanine, asparaginic acid, cysteine, glutamic acid, proline, tyrosine, glycine, sodium hydrogen sulfite, heparin, methylprednisolone sodium succinate, broad-spectrum antibiotics, antifungal drugs, FXR agonists and sterilized water for injection. The oxygen-carrying component is washed red blood cells or concentrated red blood cells or artificial blood. The viscosity of the organ maintenance liquid is closer to that of plasma, the influence on the blood coagulation function and the renal function is avoided, and the organ maintenance liquid has higher safety, can treat ischemia reperfusion injury, repair the liver biliary tract function and remarkably reduce various inflammation indexes, and is used for ischemia-free liver transplantation.
Owner:SUN YAT SEN UNIV +1

Adjustable elbow assembly for embryo transplantation catheter

The invention discloses an adjustable elbow assembly for an embryo transplantation catheter, relates to the technical field of embryo transplantation catheters, and aims to solve the technical problem that an opening of an embryo transplantation outer tube is easy to cause injury to a patient. By means of multi-structure collaborative innovation, the problems that a traditional catheter is high in damage risk, poor in adaptability and the like are solved in an all-around mode, and the catheter has the core advantages that by means of the necking design, the cervical contact area is reduced, a smooth port and a directional deformation structure are matched, scraping and lobe damage are thoroughly avoided, and the complication risk is reduced; the structures of the shaft ring and the traction rope are optimized, the necking state is kept, meanwhile, the flexibility of the pipe body is guaranteed, and smooth pipe insertion is guaranteed; multi-angle adjustment is achieved through the multi-bend arc body and the independent shifting plate, cervical canal differences of different patients are accurately adapted, and the success rate of intubation is increased; the control structure is convenient to operate, and the necking state is stable and controllable. The whole device is designed through mechanical linkage, safety, adaptability and operability are considered, and safety and comfort of an embryo transplantation operation are remarkably improved.
Owner:GENERAL HOSPITAL OF THE NORTHERN WAR ZONE OF THE CHINESE PEOPLES LIBERATION ARMY

Medical osteochondral acquisition system

The invention relates to a medical osteochondral acquisition system which comprises a trephine and a positioning sleeve, and the positioning sleeve is provided with an inner cavity matched with the trephine; wherein a liquid injection pipe is arranged on the side wall of the positioning sleeve, an injection opening is formed in the position, on the outer side of the positioning sleeve, of the liquid injection pipe, the liquid injection pipe is communicated with the inner cavity through a communication opening in the side wall of the positioning sleeve, and injection flows into the inner cavity of the positioning sleeve through the injection opening. Injection liquid is injected into the positioning sleeve through the liquid injection pipe, the cooling effect can be achieved in the clinical osteochondral transplantation operation process, the activity of the obtained tissue is improved, due to the integrated design of the liquid injection pipe and the positioning sleeve, the operation complexity is not additionally increased, and practicability and convenience are both considered.
Owner:山西医科大学第二医院(山西医科大学第二临床医学院)

Application of pigment epithelium-derived factor in corneal endothelial dystrophy

The invention provides an application of a pigment epithelium-derived factor in the aspect of treating or relieving corneal endothelial dystrophy and corneal endothelial dysfunction, in particular to an application of the pigment epithelium-derived factor in preparation of drugs for treating or relieving corneal endothelial dystrophy and corneal endothelial dysfunction. The PEDF is used for treating Fuchs corneal endothelial dystrophy for the first time, and it is proved that the PEDF can effectively relieve corneal endothelial cell injury, remarkably promote corneal transparency and thickness recovery, relieve corneal edema and promote corneal endothelial cell density, morphological repair and functional reconstruction. The method has good social value, PEDF medicine treatment has the advantages of being sufficient in source, easy and convenient to operate, low in treatment cost, small in risk and the like, and the requirements of corneal transplantation surgery in clinic can be reduced.
Owner:EYE INST OF SHANDONG FIRST MEDICAL UNIV

Preparation method and application of soft tissue-like elastic hydrogel and hydrogel tissue organ model

The present invention provides a preparation method and application of a soft tissue-like elastic hydrogel and its tissue and organ model, belonging to the technical field of hydrogel-based tissue and organ model manufacturing. The present invention utilizes acrylamide and an unsaturated double-bond monomer containing a negative electron group to perform photocuring to form a covalent cross-linking network, and then coordinates the negative electron group with zirconium ions to form an ion cross-linking network, thereby constructing a double-network elastic hydrogel with mechanical properties close to those of soft tissue and adjustable. With the advantage of light-curing rapid prototyping technology to construct fine structures, various personalized tissue and organ models that match natural soft tissues can be printed and prepared, solving the contradiction between the mechanical properties and processing properties of soft materials. The preparation method of the elastic hydrogel provided by the present invention is simple and easy, has adjustable mechanical properties, can better match soft tissues, can simulate the mechanical behavior of human soft tissues, and is expected to be applied to medical preoperative simulation, organ transplantation, and surgical resection medical fields.
Owner:LANZHOU INSTITUTE OF CHEMICAL PHYSICS CHINESE ACADEMY OF SCIENCES

Minimally invasive autologous scalp hair follicle transplantation system

To provide a minimally invasive autologous scalp hair follicle transplantation system that performs all hair transplant surgery with a single device, controls the on / off of the device with a foot switch, and performs hair transplant surgery accurately and quickly. [Solution] The minimally invasive autologous scalp hair follicle transplantation system comprises a main controller 10, a vacuum suction pre-buffer 20, a hair harvesting device 30, a hair implantation device 40, and multiple control switches 50, 50'. The main controller includes a hair harvesting device main controller 12, a negative pressure device 13, a compressor 14, and a power supply device 15. The hair harvesting device main controller is connected to the hair harvesting device via an electric wire 121 and controls the on / off and rotation speed of the motor in the hair harvesting device. The negative pressure device communicates with the vacuum suction pre-buffer via a negative pressure tube 131. The compressor communicates with the hair implantation device via a second hair implantation device tube 42.
Owner:FINE VISION ELECTRONICS CO LTD

Kidney supply storage bag applied to robot kidney transplantation operation

A kidney supply storage bag applied to a robot kidney transplantation operation belongs to the technical field of kidney storage for kidney transplantation, and is characterized by comprising thermal insulation cloth and a plurality of medical rubber mats which are transversely and uniformly distributed and connected to the upper edges of the upper and lower surfaces of the thermal insulation cloth, medical cloth liners are symmetrically connected to the left and right edges of the upper surface of the thermal insulation cloth front and back, a drainage device is inserted in an interlayer in the thermal insulation cloth, a feeding connector is connected to the circle center of the surface of one end of the drainage device, and a discharging connector is connected to the circle center of the surface of the other end of the drainage device. Low-temperature liquid is completely led out in the pipeline in a sealed mode, so that the low-temperature liquid cannot flow into the abdominal cavity, and the storage bag is separated from the intestinal canal through thick large gauze.
Owner:HARBIN MEDICAL UNIVERSITY

Crushing, sucking and transplanting device for cartilage

PendingCN121196660AEnemata/irrigatorsSurgeryPostoperative complicationCartilage transplantation
The invention provides a cartilage crushing, suction and transplantation device which comprises a device outer shell, a negative pressure suction assembly and a flushing assembly are arranged on the side edge of the device outer shell, the cartilage crushing, suction and transplantation device integrates cartilage drilling, crushing, suction and transplantation functions, integrated operation is achieved, the operation efficiency is remarkably improved, and the operation time is shortened. The negative pressure suction assembly is provided with a negative pressure pump, a negative pressure meter and an adjusting knob, the negative pressure can be accurately regulated and controlled, the requirements of different patients are met, and tissue damage or incomplete suction is avoided. The flushing assembly is composed of a flushing tank, a pump, a pipeline and a filtering tank, the operation area is continuously flushed, chippings are removed, the visual field is kept clear, effective cooling is achieved, heat injury is prevented, and the risk of postoperative complications is reduced. A U-shaped groove is formed in the operation tube placing frame, so that the suction tubes can be stably stored and quickly taken, and disordered damage is avoided. The system is strong in integration function and suitable for various cartilage transplantation operation scenes.
Owner:175TH HOSPITAL OF PEOPLES LIBERATION ARMY

Tool for obtaining free soft tissue valve in oral soft tissue transplantation operation

The invention relates to a tool for obtaining free soft tissue flaps in oral soft tissue transplantation surgery, which comprises a handle and a working structure fixed at the front end of the handle, the working structure is made of medical-grade metal materials, and the whole working structure is of an arc shovel-shaped structure and is matched with the radian of an alveolar bone; a working blade is arranged at the front end of the working structure, a depth limiting structure used for limiting the shoveling depth is arranged on the side portion of the working structure, the position of the depth limiting structure is relatively higher than the working blade, and a preset height difference exists between the depth limiting structure and the working blade. The tool ensures that the thickness of the soft tissue valve obtained every time is accurate and uniform through the working head with the standardized thickness and width, obtaining can be completed through one-time cutting and propelling, and the operation efficiency is improved.
Owner:ZHONGSHAN HOSPITAL FUDAN UNIV