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85results about How to "Have affinity" patented technology

Cyanine fluorescent compound as well as preparation method and application thereof

ActiveCN109180556ASolve the problem of not being able to pass the blood-brain barrierStrong penetrating powerOrganic chemistryIn-vivo testing preparationsDouble bondStructural formula
The invention belongs to the field of specific molecular recognition materials and discloses a cyanine fluorescent compound as well as a preparation method and application thereof. The structural general formula of the cyanine fluorescent compound is shown as a formula (I). The fluorescent compound disclosed by the invention adopts a classic cyanine dye structure, an electroneutral electron-drawing group is introduced into the R-group position, a conjugated structure of push-pull electron interaction is formed between the electron-donating group and the electron-drawing group in the structure,and the conjugated system for transition is increased by carbon-carbon double bonds, so that fluorescence produced by compound molecules moves to a near infrared region. Meanwhile, due to the introduced electroneutral group, the problem that most of the charged cyanine compounds cannot pass through the blood brain barrier is solved. The compound molecule has affinity to Abeta plaques, can be successfully applied to near infrared fluorescence imaging of the Abeta plaques, and has the advantages of being safe, non-radioactive, low in cost, low in background fluorescence interference, high in penetrating power in biological tissues and the like. The structural formula is as shown in the specification.
Owner:SOUTH CHINA UNIV OF TECH

Rare earth polishing powder and preparation method thereof

The invention relates to rare earth polishing powder, which is uniform solid solution with the crystal forms of fluorine oxide rare earth and cubic phase rare earth oxide. The invention further discloses a preparation method for the rare earth polishing powder. The preparation method comprises the steps of preparation of rare earth aqueous solution, precipitation, dehydration, roasting, smashing and the like. The prepared rare earth polishing powder is uniform solid solution with the crystal forms of fluorine oxide rare earth and cubic phase rare earth oxide. According to the rare earth polishing powder and preparation method thereof, F is introduced in precipitation process, the later fluorization step can be omitted, and the preparation method has the advantages of being simple in process, low in cost, and less in waste water. Through adding ammonia sulfate in the precipitation process, when high-temperature roasting is performed, on one hand, the condition that crystal lattices of the main active ingredient cerium oxide in the polishing powder are disordered to form activated cerium oxide can be ensured, so that the activated cerium oxide and glass surface have affinity, the chemical activity of the polishing powder can be enhanced, and further the polishing mass of the polishing powder can be promoted; on the other hand, the cubic crystal form of the rare earth oxide can be ensured, and the polishing mass increase can be promoted.
Owner:上海华明高纳稀土新材料有限公司

Sodium alginate microspheres blood vessel suppository containing etoposide and preparation method and uses thereof

The invention belongs to the field of medical embolization devices, relates to a sodium alginate microsphere targeted vascular embolization agent containing an antineoplastic drug and a preparation method thereof. Alginic acid is taken as a pharmaceutical carrier, the antineoplastic drug etoposide is a pharmaceutical active ingredient, divalent metal cation or calcium ion solution is taken as a solidifying agent, and the sodium alginate encapsulates the etoposide to prepare ideal particle size-controllable sodium alginate microspheres comprising the etoposide, thus avoiding toxic side effect of traditional etoposide administration such as anaphylaxis and inconvenience. The vascular embolization agent changes the dosage form and route of administration way of the antineoplastic drug etoposide, has high efficacy and low toxicity, and is safely and effectively applied to clinical application. The vascular embolization agent has the advantages of mild preparation condition and simple and convenient operation, and is fit for large-scale production. The vascular embolization agent can be used for vascular embolization, local targeted tumor treatment, and treating small-cell carcinoma of the lung, oophoroma, carcinoma of testis, gastric cancer and liver cancer by administering the vascular embolization agent during operations.
Owner:BEIJING SHENGYIYAO SCI & TECH DEV

Touch input assembly, touch control air-conditioner and control method

The embodiment of the invention provides a touch input assembly, a touch control air-conditioner and a control method and relates to the technical field of electrical equipment. Index parameter values can be adjusted and set precisely, and operation is simple. The touch input assembly comprises a display panel. The display panel is provided with multiple selection buttons and a sliding touch setting area. The multiple selection buttons and the sliding touch setting area are electrically connected with a controller. Each selection button corresponds to one set index parameter. When any selection button is touched, the controller controls the sliding touch setting area to correspond to the set index parameters of the selection buttons. When the sliding touch setting area is touched in a sliding manner, the controller correspondingly adjusts the values of the set index parameters according to the touch control positions or the touch control directions of the sliding touch setting area. The touch control positions of the sliding touch setting area correspond to the values of the set index parameters one by one. According to the embodiment, the touch input assembly is used for manufacturing an air-conditioner.
Owner:HISENSE (SHANDONG) AIR CONDITIONING CO LTD

AI interactive light art device

The invention relates to the technical field of interactive light art devices, and discloses an AI interactive light art device. The AI interactive light art device comprises a connecting device, a signal collecting device, a data processing device, a display device and an auxiliary device, the virtual reality technology and the dynamic capture technology are mixed, the AI interactive lamplight art device is further development of the virtual reality technology, through mixed reality, a user can make contact with the real environment while manipulating a virtual image, and the sensory property is enhanced, and the action of capturing an object is generated. According to the invention, the action data is combined with a real-time image interaction system, so that an interaction effect of tight combination is generated between participants and interactive landscape light show, and the interactive landscape light show is realized by utilizing increasingly mature intelligent control technologies such as interactive light, space sound and AI artificial intelligence. Light is not limited to single functional illumination any more, and artistic creation is carried out by utilizing physical characteristics of light, so that life is more intelligent and humanized.
Owner:SHENZHEN DATE ENG TECH

Preparation method of cattle-hide collagen fibers as well as prepared cattle-hide collagen fibers and application thereof

The invention provides a preparation method of cattle-hide collagen fibers as well as prepared cattle-hide collagen fibers and application thereof and relates to the technical field of textiles. According to the preparation method of cattle-hide collagen fibers, with the adoption of a manner of stirring and throw-softening cow leather during soaking, the cow leather can fully absorb treating fluidduring stirring so as to achieve an optimal expanding and softening effect. Moreover, in an opening step of a subsequent process, cattle-hide collagen fiber bundles are beaten by using elastic materials, and physical damage and pressure in the subsequent process can be reduced, so that the cattle-hide collagen fiber prepared by the method have excellent physical and mechanical properties, and quality requirements of prepared textile articles can be met. Moreover, the cattle-hide collagen fibers have the effects of being antibacterial, deodorant, moisture-absorbing, quick-drying, warm and airpermeable, natural flame retardant, skin-friendly, capable of preserving health and the like, and the technical problem in the prior art that a method for producing high-quality cattle-hide collagen fibers does not exist is solved.
Owner:嘉兴奥克兰特种牛皮科技有限公司
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