The invention discloses a heat-resistant cross-linked high-density polyethylene pipe. The pipe is prepared from the following raw materials: high-density polyethylene, polybutadiene, 3methacryloyloxytrimethoxysilane, montmorillonite powder, an ethylene-vinyl acetate copolymer, a styrene-maleic anhydride copolymer, an olefin processing mixed additive, a lubricant, a cross-linking agent, an assistant cross-linking agent, polycarbosilane, N-ethyl-o-toluenesulfonamide, 4,4'-diaminodiphenyl sulfone, an ethylene-octene copolymer, cobalt sesquioxide, resorcinol and cordierite powder. According to theheat-resistant cross-linked high-density polyethylene pipe disclosed by the invention, the heat resistance and the creep resistance are improved, meanwhile, the ageing resistance, the mechanical property, the transparency and the like of the pipe are obviously improved, and if the crosslinking degree is improved, the improvement of the properties is more obvious. Meanwhile, the pipe has better chemical corrosion resistance and flexibility.