26 results about "Alcohol synthesis" patented technology

The invention discloses a preparation method of a carbon shell confinement type nickel-bismuth-titanium composite catalyst and application of the carbon shell confinement type nickel-bismuth-titanium composite catalyst in high alcohol synthesis, and belongs to the technical field of catalysts. The preparation method of the carbon shell confinement type nickel-bismuth-titanium composite catalyst comprises the following steps: dissolving nickel salt, titanium dioxide and citric acid in water to form a homogeneous solution; adding bismuth salt into the homogeneous solution, and drying to obtain a precursor; and roasting the precursor to obtain the carbon shell confinement type nickel bismuth titanium composite catalyst. The carbon shell confinement type nickel-bismuth-titanium composite catalyst provided by the invention shows excellent catalytic performance in a reaction system for synthesizing high-carbon alcohol through carbon-carbon coupling of water-phase alcohol molecules. According to the catalyst, the high-carbon alcohol yield can reach 45.04% while high organic phase selectivity is maintained, and compared with a traditional nickel-bismuth-based catalyst, the high-carbon alcohol yield is remarkably improved.

The invention discloses a high-stability carbonyl reductase mutant and application of the high-stability carbonyl reductase mutant in chiral alcohol synthesis. An amino acid sequence as shown in SEQ ID NO.2 is mutated as follows: 20th leucine is replaced by any one of lysine, threonine, aspartic acid or isoleucine, and / or 55th leucine is replaced by any one of methionine, serine, lysine or isoleucine, and / or 55th leucine is replaced by any one of methionine, serine, lysine or isoleucine. Compared with a wild type enzyme, the stability of the obtained mutant is remarkably improved, particularly, single-point mutants Mut-L20I and Mut-L55I and a combined mutant Mut-L20I-L55I show excellent relative enzyme activity, thermal stability and substrate tolerance. The mutant has high catalytic activity and stability to various chiral alcohols, has the advantages of high catalytic efficiency, high thermal stability, strong substrate tolerance, easiness in fermentation production and the like, and is suitable for industrial application of enzymatic synthesis of chiral alcohols.

The method specifically comprises the following steps: adding a copper source and a magnesium source into deionized water, stirring and dissolving, dropwise adding a silicon source and a template agent, keeping uniform, continuously dropwise adding a NaOH solution, and finally stirring at room temperature for 3-5 hours to form gel; transferring the obtained gel into an autoclave for hydrothermal crystallization reaction, taking out a sample, washing the sample with deionized water, carrying out vacuum drying in a vacuum drying oven, calcining the dried sample in a muffle furnace, removing the template agent, and reducing the dried sample in reducing gas to obtain the catalyst Cu / Mg-MCM-22, filling a reaction tube with the prepared catalyst Cu / Mg-MCM-22, placing the reaction tube in a fixed bed reactor, introducing shielding gas, and pumping coal alcohol for reaction. By synthesizing the copper-based catalyst Cu / Mg-MCM-22 and using the coal-based alcohol as the raw material, the synthesis process is simple in reaction process, economical and practical, and the catalyst is high in acetaldehyde selectivity, good in stability and long in service life.

The invention relates to the technical field of organic alcohol synthesis, and discloses a method for synthesizing isononyl alcohol. The method comprises the following steps: (1) mixing octylene, a rhodium catalyst and a phosphine ligand, then introducing synthesis gas into the obtained mixture, and carrying out hydroformylation reaction to obtain isononanal; (2) in the presence of a hydrogenation catalyst, mixing the isononanal with hydrogen for hydrogenation reaction; wherein the phosphine ligand is selected from two or more of triphenyl phosphite, tris (2, 4-di-tert-butylphenyl) phenyl phosphite, triphenylphosphine, 6, 6 '-{[5, 5'-dimethoxy-3, 3 '-bis (2-methyl-2-propyl)-2, 2'-biphenyl diyl] bis (oxy)} bis [dibenzo (d, f) (1, 3, 2) dioxaphosphoheptane] and 4, 5-bis (diphenylphosphine)-9, 9-dimethyl xanthene. According to the method, the conversion rate of mixed octylene in the hydroformylation process and the selectivity and yield of isononyl aldehyde can be remarkably improved, so that the yield of isononyl alcohol is improved, reaction conditions are mild, and the method has remarkable economic value and wide industrial application prospects.

The invention discloses a method for producing bio-based dihydric alcohol. According to the method, bio-based methyl 2-tetrahydrofuroate, tetrahydrofurfuryl propionate and methyl 2-(tetrahydrofuran-2-yl) acetate are used as precursors for dihydric alcohol synthesis, Cu-Ga-Mn / SiO2 or Cu-Ga-Mn / SiO2-Al2O3 is used as a hydrogenation catalyst, cyclic ether ester structures are synchronously activated in a fixed bed reactor, ester group hydrogenation and tetrahydrofuran ring opening are synergistically carried out, and the high-purity tetrahydrofuran is obtained. The reaction path is shortened. The hydrogenation catalyst is prepared by combining a sol-gel method and hydrothermal synthesis through roasting and reduction, active components are uniformly distributed, and the hydrogenation catalyst has excellent hydrogenation activity and structural stability.

The utility model discloses an efficient distillation and separation device for side chain alcohol synthesis, which relates to the technical field of distillation and separation devices and comprises a device table, an electric heating round seat is integrally formed at the upper end of the device table, a seat leaning plate is arranged on one side of the electric heating round seat, and the seat leaning plate and the device table are of an integral structure. An electric push rod is fixedly arranged on the outer wall of one side of the seat leaning plate through a screw; the distillation retort is mounted in the electric heating round seat, a top sealing cover is arranged right above the distillation retort, a vacuum suction pump is arranged at the rear end of the electric heating round seat, and a suction pipe of the vacuum suction pump is communicated with the interior of the distillation retort; the condensation tank is arranged on one side of the distillation tank, and the problem that the side-chain alcohol synthesis effect is affected due to the fact that the existing distillation device lacks protection on thermosensitive substances in the using process and the thermosensitive substances needed by side-chain alcohol synthesis can be decomposed by the distillation device for side-chain alcohol synthesis is solved.

The invention relates to the technical field of penetrant JFC preparation, and discloses a double-metal cyanide catalyst and a preparation method thereof, and a preparation method of low-carbon fatty alcohol polyether. The preparation method of the double-metal cyanide catalyst comprises the following steps: mixing soluble transition metal salt, cyano metal salt, a reaction medium and a dispersing agent, and then reacting in an inert atmosphere, wherein the cyano metal salt is K3 [M (CN) 6], and the metal M is selected from at least one of Co, Fe and Cr. The double metal cyanide catalyst can effectively reduce the temperature for synthesizing polyether from low-carbon alcohol, has high catalytic reaction activity, and can reduce free alcohol residues in the reaction process. Meanwhile, the catalyst does not react with the initiator to generate water, so that the generation of a polyethylene glycol byproduct can be reduced.

The invention provides a higher alcohol synthesis catalyst capable of being mixed with ship fuel as well as a preparation method and application of the higher alcohol synthesis catalyst, and belongs to the technical field of catalysts. The preparation method comprises the following steps: dissolving nickel salt and bismuth salt in deionized water, and stirring to form a homogeneous solution; adding CeO2 into the homogeneous solution, stirring, and drying to obtain a precursor; and roasting the precursor in an inert atmosphere to obtain the higher alcohol synthesis catalyst capable of being mixed with the ship fuel. According to the catalytic system, through well-designed metal-carrier interaction, reaction conditions are remarkably optimized, the selectivity of the catalyst to long-chain alcohol products is remarkably improved while high activity of the catalyst is kept, and adjustable oxygen vacancies on the surface of the CeO2 carrier in the catalyst can stabilize reaction intermediates and remove surface carbon deposition, so that the selectivity of the catalyst to the long-chain alcohol products is improved. A guarantee is provided for long-term recycling of the catalyst, and the catalyst is easy to separate, recycle and reuse in a higher alcohol preparation process.

The present application relates to a kind of green alcohol and green ammonia co-production system and method based on traditional coal methanol device and high temperature fuel cell electrolytic cell, belong to fuel cell technical field.The green alcohol and green ammonia co-production system includes: raw material pretreatment and vaporization module, coal gas purification module, methanol synthesis and gas-liquid separation module, SOFC power generation and CO2 enrichment module, SOEC electrolysis module, green alcohol synthesis module and green ammonia synthesis module.The green alcohol and green ammonia co-production system is through "electric-chemical-carbon" synergic cycle, simultaneously solves renewable energy consumption and high carbon chemical decarburization two big problems, realizes green alcohol and green ammonia efficient co-production.

The invention discloses a synthesis method of bis-chiral beta-halohydrin, and belongs to the technical field of enzyme engineering. The synthesis method of the double-chiral beta-halohydrin comprises the following steps: co-dissolving a substance containing cytochrome P450 monooxygenase and a racemization substrate in a solvent to obtain a reaction solution, carrying out catalytic reaction on the reaction solution at 20-40 DEG C for 20-30 hours, then centrifuging, collecting supernate, extracting and concentrating to obtain the double-chiral beta-halohydrin, the amino acid sequence of the cytochrome P450 monooxygenase is as shown in SEQ ID NO.1, and the structural formula of the racemic substrate is as shown in formula I, formula II or formula III. Wherein R1 is hydrogen, fluorine, chlorine, bromine, methyl or methoxyl, R2 is hydrogen or methyl, R3 is fluorine, chlorine or bromine, and R4 is fluorine, chlorine or bromine. The bichiral beta-halohydrin prepared by the biological catalysis method provided by the invention can solve the problems of low enzyme activity, tedious steps, high cost and the like in the prior art.

The invention discloses a preparation method of a catalyst for synthesizing isomeric alcohol, and the preparation method comprises the following steps: S1, dissolving cobalt salt, copper salt and a carrier with high specific surface area in a solvent through ultrasonic dispersion, mixing, dipping, stirring, and aging to obtain a precipitate; s2, stirring and refluxing the precipitate and a 2-methylimidazole solution together, aging again, washing with absolute ethyl alcohol, and drying to obtain a catalyst precursor; and S3, calcining the catalyst precursor twice in different gas atmospheres to obtain the catalyst for synthesizing the isomeric dihydric alcohol. The catalyst prepared by the method is used for carrying out molecular addition on synthesis gas (CO + H2) and formaldehyde through a formaldehyde hydroformylation route to obtain isomeric dihydric alcohol, has the advantages of high product selectivity, good catalytic activity, environmental protection, low price and the like, can improve the selectivity of isomeric dihydric alcohol synthesis reaction, and is suitable for industrial production. The ever-increasing requirements of the chemical fiber field on low-cost and high-performance polyester raw materials are favorably met.

In the system, a wind-solar power generation unit is connected with a hydrogen production and poly-generation module, and a photo-thermal heat supply unit is connected with a cascade fused salt heat storage module; the cascade fused salt heat storage module comprises a hot fused salt storage tank and a cold fused salt storage tank; the hydrogen production and poly-generation module comprises an SOEC unit, a thermoelectric ammonia / alcohol synthesis unit and a thermoelectric circulation unit, and the cascade molten salt heat storage module provides high-temperature molten salt for the thermoelectric circulation unit to drive power generation, provides high-temperature molten salt for the SOEC unit to produce hydrogen and provides high-temperature, medium-temperature and / or low-temperature molten salt for the thermoelectric ammonia / alcohol synthesis unit to supply unit energy. The hot molten salt returns to the cold molten salt storage tank after completing the set heat supply target and reaching the set temperature of the cold molten salt storage tank; the output end of the thermoelectric circulating unit is connected with the SOEC unit and the thermoelectric ammonia / alcohol synthesis unit to supply power; the input end of the power storage module is connected with the wind-solar power generation module and the thermoelectric cycle unit, and the output end is connected with the hydrogen production and poly-generation module.

The invention relates to the technical field of catalysts, in particular to a copper-silicon catalyst for synthesizing high alcohols and a preparation method thereof.The copper-silicon catalyst comprises an active component, a carrier and an auxiliary, the active component is copper element, and the copper element is derived from copper nitrate trihydrate; the carrier is a silicon-based carrier, and the silicon-based carrier is derived from liquid silicon; the auxiliary agent is a calcium element, and the calcium element is derived from calcium nitrate tetrahydrate. According to the invention, a copper-silicon-calcium system is adopted to construct the catalyst, copper nitrate trihydrate is adopted to provide an active component copper, liquid silicon is adopted to provide a silicon-based carrier, calcium nitrate tetrahydrate is adopted to provide an auxiliary calcium, and the raw material ratio is accurately controlled, so that high-loading active components are not needed on the premise of ensuring the activity, and the raw material cost for preparing the catalyst is remarkably reduced; meanwhile, the cost control difficulty in subsequent industrial application is simplified, and a cost basis is provided for large-scale popularization of a technology for preparing high-carbon alcohol from synthesis gas.

This invention relates to a phenylpyruvate decarboxylase mutant for the synthesis of phenylethanol and its applications, belonging to the fields of enzyme engineering and genetic engineering. To address the technical problems of low catalytic efficiency, poor substrate affinity, and insufficient stability of existing phenylpyruvate decarboxylases, which lead to low biosynthetic efficiency and limited yield of phenylethanol, making it difficult to meet the needs of industrial production, this invention provides a phenylpyruvate decarboxylase mutant for the synthesis of phenylethanol. This mutant offers a new and highly efficient synthetic element for the biosynthesis of phenylethanol, with broad application prospects and market potential in the field of higher alcohol synthesis.

The application discloses a carbon-coated nickel-based super-hydrophobic catalyst and a preparation method and application thereof, and belongs to the technical field of catalysts and high-alcohol synthesis. In the application, nickel salt and citric acid are dissolved in water, and then the obtained mixed solution is heated and stirred to obtain a precursor; the precursor is calcined under an inert atmosphere to obtain a carbon-coated nickel-based catalyst; and the carbon-coated nickel-based catalyst is ball-milled with polytetrafluoroethylene to obtain a carbon-coated nickel-based super-hydrophobic catalyst. In the application, the carbon-coated nickel-based catalyst is prepared first, and then coupled with the hydrophobic polymer polytetrafluoroethylene to form a new super-hydrophobic catalyst. The nickel-based catalyst and the polytetrafluoroethylene are ball-mixed, the hydrophobic performance of the nickel-based catalyst is improved, the water "poisoning" phenomenon of the catalyst is relieved, the coupling of low-alcohol to high-alcohol is further promoted, the yield of high-alcohol and the selectivity of C6+ high-alcohol are improved, and the application prospect is wide.

The present invention relates to a process for producing a low carbon strength oil, comprising the steps of: providing a feed mixture comprising: a carbonaceous material; one or more alcohols and / or polyols in a concentration of at least 5% by weight; converting the feed mixture at a pressure of from 10 bar to 400 bar and a temperature of from 280 DEG C to 430 DEG C; recovering a low carbon strength oil from the converted feed mixture; recovering at least a portion of the gas produced from the converted feed mixture, the converted feed mixture comprising the carbon oxides resulting from the conversion, and providing at least a portion of the recovered gas to an alcohol production plant for alcohol production using hydrogen in an alcohol synthesis process; wherein the recovery gas from the converted feed mixture is used in the alcohol production plant to produce at least a portion of the alcohol forming portion of the feed mixture.

The application discloses a preparation method of a carbon shell limited type nickel-bismuth-titanium composite catalyst and application of the catalyst in high-carbon alcohol synthesis, and belongs to the technical field of catalysts. The preparation steps of the carbon shell limited type nickel-bismuth-titanium composite catalyst are as follows: nickel salt, titanium dioxide and citric acid are dissolved in water to form a homogeneous solution; bismuth salt is added into the homogeneous solution, and a precursor is obtained through drying; the precursor is calcined to obtain the carbon shell limited type nickel-bismuth-titanium composite catalyst. The carbon shell limited type nickel-bismuth-titanium composite catalyst provided by the application exhibits excellent catalytic performance in a water-phase alcohol molecule carbon-carbon coupling reaction system for synthesizing high-carbon alcohol. While maintaining high organic phase selectivity, the high-carbon alcohol yield of the catalyst can reach 45.04%, which is significantly improved compared with traditional nickel-bismuth-based catalysts.

The present application relates to the technical field of alcohol synthesis, in particular to a kind of catalyst and its preparation method and application and the method for synthesizing methanol.The catalyst of the present application includes: modified aluminum-based metal organic framework and active component copper oxide and zinc oxide supported on the modified aluminum-based metal organic framework, wherein the modified aluminum-based metal organic framework is the product obtained by etching aluminum-based metal organic framework.The preparation method of the catalyst of the present application includes: (1) etching aluminum-based metal organic framework with a solution to obtain product 1;(2) the product 1 is precipitated with copper-zinc solution to obtain product 2;(3) the product 2 is dried and calcined to obtain the catalyst.When the catalyst of the present application is applied to the reaction of preparing methanol from synthesis gas, it has high catalytic activity and thermal stability.

The present application relates to the technical field of catalyst, in particular to a preparation method of an enhanced industrial catalyst for direct synthesis of alcohol from synthesis gas, the preparation method comprising: impregnating a SiO2 carrier with an impregnation solution to obtain a preliminary catalyst, and then aging, drying and calcining; the preparation method further comprises a structure enhancement treatment of the carrier and / or the preliminary catalyst, the structure enhancement treatment being selected from one or more of steps A and B; the step A comprises subjecting the carrier and / or the preliminary catalyst to superheated steam treatment; the step B comprises subjecting the carrier and / or the preliminary catalyst to hydrothermal reaction in an aqueous sol solution, the sol comprising one or more of a silicon sol, an aluminum sol and a zirconium sol. The preparation method greatly improves the mechanical strength of the catalyst under the premise of maintaining high activity of the catalyst through the structure enhancement treatment, and focuses on solving the requirement of the industrial catalyst for the mechanical strength of the catalyst.

The invention discloses a preparation method of a solid-phase catalyst and application of the solid-phase catalyst in catalytic synthesis of nitrophenoxy alcohol, the solid-phase catalyst with high reaction activity is obtained by performing surface modification on silicon dioxide, and the solid-phase catalyst has high reaction activity and selectivity when being used for transesterification catalytic nitrophenoxy alcohol reaction; besides, when the catalyst is used for synthesizing nitrophenoxy alcohol, the solid-phase catalyst is filled in a fixed bed, and nitrophenol and carbonic ester serving as raw materials flow through the fixed bed reactor filled with the catalyst to react, so that a reaction solvent is not needed, the reaction selectivity is good, and almost no side reaction occurs; pure nitrophenoxy compounds can be obtained only by removing unreacted raw materials and byproducts, and the method has the advantages of milder reaction conditions, convenience and rapidness in separation, suitability for industrial continuous production and the like, and has remarkable industrial potential.

This invention relates to the field of asymmetric hydrogenation technology, specifically disclosing an electron-rich chiral bisphosphine ligand, specifically L1 to L5, and disclosing the synthetic pathways of ligands L1 to L5 and the intermediate compounds 1 to 5 in the synthetic route. This invention uses L1 to L7 to complex with different transition metal precursors, such as [Rh(COD)2]BAr. F 4. A series of stable, simple-to-prepare, and low-cost catalysts were obtained, including [Rh(NBD)2]BF4, [Rh(NBD)Cl]2, Rh(acac)(CO)2, Rh(ethylene)2(acac), and [Rh(ethylene)2Cl]2. These catalysts can be used for asymmetric hydrogenation, especially in the asymmetric hydrogenation step of the N-Boc amino alcohol synthesis pathway, effectively overcoming the steric hindrance effect under different amino protecting group conditions. With the participation of this catalyst, the asymmetric hydrogenation step in the N-Boc amino alcohol synthesis pathway overcomes the technical defects of using hazardous materials in existing technologies, improving the production safety factor. Furthermore, with the participation of this catalyst, the asymmetric yield and selectivity both meet the requirements of industrial production.

The application provides a carbonyl reductase mutant and application thereof in chiral ketone resolution and chiral alcohol synthesis. The mutant protein is a non-natural protein, and the mutant protein can recognize the chirality of a cyclic diketone, selectively reduce a certain configuration ketone in the cyclic diketone into a single configuration alcohol, and retain another configuration ketone. The carbonyl reductase mutant of the application is applied to a production process of a key starting material of melagatran to convert 100-500 g / L of a substrate for complete resolution, and retain (1R, 5S)-configuration ketone. The application lays a foundation for green biological manufacturing of (1R, 5S)-chiral ketone.

The invention relates to the field of green energy utilization transformation, and provides a hydrogen-ammonia-alcohol synthesis method and system for electrohydrogen production coupled coal chemical industry. The hydrogen-ammonia-alcohol synthesis method comprises the following steps: synthesizing ammonia and alcohol by utilizing hydrogen produced by partial electric hydrogen production and coal hydrogen production; and adjusting the hydrogen-carbon molar ratio and synthesizing alcohol in a hydrogen-carbon conversion link by using the other part of hydrogen of the electric hydrogen and the coal hydrogen so as to realize co-production proportion regulation and control of the hydrogen, the ammonia and the alcohol. According to the hydrogen-ammonia-alcohol synthesis method, renewable energy sources and fossil resources are fully utilized, and complementation and efficient utilization of the resources are achieved; the carbon emission in the production process can be obviously reduced; the flexible regulation and control of the co-production proportion of hydrogen, ammonia and alcohol can be realized; not only can the flexible adjustment of a long-term plan be met, but also day-ahead, intra-day and real-time adjustment can be realized, and the adaptability of the hydrogen-ammonia-alcohol synthesis method to the fluctuation of a power grid is improved.

To provide a catalyst that enables conversion of carbon dioxide to alcohol.SOLUTION: In one aspect, the present invention provides a catalyst for alcohol synthesis comprising a) Fe; b) at least one selected from Zn and Cu; and c) at least two elements selected from the group consisting of Li, Na, K, Rb, Cs, Mg, Ca, Sr, and Ba, including K and at least one other element, or Cs and at least one other element. In another aspect, the present invention provides a catalyst for alcohol synthesis comprising a) Fe; b) at least one selected from Zn and Cu; c) at least one selected from K and Cs; and d) at least one selected from the group consisting of Ga, Y, Nb, Cd, Nd, Tb, Er, Yb, Ta, W, and Re.SELECTED DRAWING: None

The utility model provides a system and equipment for producing alcohol substances through methane dry reforming and parallel low-carbon alkane dehydrogenation. The system comprises a low-carbon alkane dehydrogenation device and an alcohol substance synthesis device, the low-carbon alkane dehydrogenation device comprises a low-carbon alkane dehydrogenation unit, the low-carbon alkane dehydrogenation unit is provided with an alkane inlet, a first alkane outlet and a second alkane outlet, the alkane inlet is used for conveying low-carbon alkane to the low-carbon alkane dehydrogenation unit, the first alkane outlet is used for outputting hydrogen, and the second alkane outlet is used for outputting olefin; the alcohol substance synthesis device comprises an olefin hydroformylation unit and an alcohol synthesis unit, a first inlet of the olefin hydroformylation unit is communicated with the second alkane outlet, a first inlet of the alcohol synthesis unit is communicated with the first alkane outlet, an outlet of the olefin hydroformylation unit is communicated with a second inlet of the alcohol synthesis unit, and a second inlet of the alcohol synthesis unit is communicated with the second alkane outlet. The second inlet of the olefin hydroformylation unit is also communicated with the methane dry reforming device; in the production process, the carbon dioxide emission can be reduced, and the energy consumption is reduced.

The present invention relates to the technical field of asymmetric hydrogenation. Particularly disclosed is an electron-rich chiral diphosphine ligand. The ligand is particularly L1-L5. Further disclosed are synthesis routes of the ligands L1-L5 and intermediate compounds 1-5 in the synthesis routes. In the present invention, L1-L7 are used to complex with different transition metal precursors, such as [Rh(COD)2]BArF 4, [Rh(NBD)2]BF4, [Rh(NBD)Cl]2, Rh(acac)(CO)2, Rh(ethylene)2(acac) and [Rh(ethylene)2Cl]2, so as to obtain a series of catalysts which are stable in terms of properties, simple to prepare and low in terms of cost. The catalysts can be used for asymmetric hydrogenation and particularly can be used for an asymmetric hydrogenation step in an N-Boc amino alcohol synthesis path, thereby effectively overcoming the steric effect under different conditions of amino protecting groups. Under the participation of the catalysts, the technical defect of dangerous articles being used in the prior art is overcome by the asymmetric hydrogenation step in the N-Boc amino alcohol synthesis path, such that the production safety coefficient is improved, and the asymmetric yield and selectivity both satisfy the industrial production requirements under the participation of the catalysts.