15 results about "Hexyne" patented technology

The invention provides a purification method of a naphthalimide high-purity electronic-grade photoacid generator. The method solves the problem that photo-acid cannot be purified by traditional recrystallization or directly through ion exchange columns and other methods. The method comprises the following steps: firstly synthesizing and preparing 1, 3-diketone-2-hydroxy-6-(1-hexyne) benzisoquinoline, then reacting with triethylamine and trifluoromethylsulfonyl chloride to generate a crude product 1, 3-diketone-2-(1, 1, 1-trifluoromethyl) methanesulfonic ester-6-(1-hexyne) benzisoquinoline, removing impurities from normal hexane to obtain a pure product, sublimating the material into a gas phase by using a quartz vacuum sublimation instrument, and purifying to obtain the 1, 3-diketone-2-(1, 1, 1-trifluoromethyl) methanesulfonic ester-6-(1-hexyne) benzisoquinoline. And then passing through Pure MTS9500 amino phosphonic acid type chelating resin, and finally cooling in a quartz tube to obtain the high-purity electronic-grade photoacid generator. According to the invention, the stability is high, the metal ion content is low, the purification process is convenient to process, the product is used as a photoresist-level core main material, the product is widely applied in the fields of semiconductor photoresist, other imaging systems, photocureable coatings and the like, the market scale is continuously expanded, and the product is an indispensable key material in semiconductor manufacturing and other related fields.

This invention relates to the field of electrochromic thin film technology, and more particularly to a dithiophene derivative, its preparation method, and its application, as well as an electrochromic thin film and its preparation method. This invention involves reacting dithiophene with tributyltin chloride to generate tin-modified dithiophene, reacting dithiophene with isopropanol pinacol boronic acid ester to generate boron-modified dithiophene, and then reacting the tin-modified or boron-modified dithiophene with 1,4-diiodo-2,5-bis-(6-hexynyl)-benzene to generate 1,4-dithiophene-2,5-bis-(6-hexynyl)-benzene. This product is then reacted with dimethylboron hydride generated from lithium aluminum hydride and dimethoxyethane to finally obtain the dithiophene derivative. This derivative can be applied in electrochromic thin films. This invention successfully prepares an electrochromic thin film with fast response and fluoride ion detection capability by electrochemically polymerizing the dithiophene derivative.

This invention discloses a method for the selective hydrogenation of 2,5-dimethyl-3-hexyn-2,5-diol to prepare 2,5-dimethyl-2,5-hexanediol, comprising: using 2,5-dimethyl-3-hexyn-2,5-diol as a raw material and Ru / rGO as a catalyst, carrying out a catalytic reaction in a solvent under hydrogen pressure of 0.5-3 MPa and temperature of 30-120℃ to obtain 2,5-dimethyl-2,5-hexanediol; Ru / rGO comprises reduced graphene oxide support and active component Ru, and the mass ratio of active component Ru to reduced graphene oxide support is 0.9-5:100. The catalyst of this invention can effectively suppress the hydrogenolysis reaction of hydroxyl groups during the hydrogenation process, achieving a conversion rate of up to 100% and a yield of 2,5-dimethyl-2,5-hexanediol of over 99.8%, demonstrating significant industrial application value.

This invention discloses a benzene distillation extraction process for 2,5-dimethyl-2,5-hexynylenediol and its application. The benzene distillation extraction process includes: distilling off all benzene from a hexynylenediol-benzene solution in a benzene recovery tower to obtain a concentrated hexynylenediol solution; mixing the concentrated hexynylenediol solution with fresh benzene and process condensate and / or demineralized water for extraction, followed by extraction into an extract separator to separate the oil and aqueous phases. To remove low-boiling impurities, this invention distills off all benzene under negative pressure during the benzene distillation process, ensuring that low-boiling impurities are removed along with the solvent benzene, avoiding emulsification during extraction. Fresh benzene is then added for extraction, dissolving high-boiling impurities in the benzene phase. The separation time is short and emulsification does not occur. Furthermore, the extraction rate is improved by optimizing the extraction process, achieving a rate close to 100%.

The invention discloses a method for synthesizing a marine natural product Soldelalactone A, which comprises the following steps of: adding Soldelalactone A into a reaction kettle; the method comprises the following steps: by taking 6-triisopropyl siloxyhexyl-1-alkyne (2) as a raw material, firstly, carrying out asymmetric ethynylation reaction to obtain (S, E)-4-hydroxy-10-triisopropyl siloxydecan-2-ene-5-ethynoic acid ethyl ester (4); the preparation method comprises the following steps: preparing (R)-7-((1R, 2R)-2-formyl cyclopropyl)-heptyl-1, 7-lactone (11) by virtue of a multi-step reaction, such as DIBAL-H reduction, Simmons-Smith reaction, Yamagguchi esterification and the like, so as to obtain (R)-7-((1R, 2R)-2-formyl cyclopropyl)-heptyl-1, 7-lactone (11); the preparation method comprises the following steps: reacting Soldelalactone A with (S, 1E, 5Z)-1-iodoundecane-1, 5-diene-3-alcohol (12), and finally reacting with (S, 1E, 5Z)-1-iodoundecane-1, 5-diene-3-alcohol (12) to obtain According to the method, asymmetric ethynylation is applied to synthesis of Soldelalactone A for the first time, and the method has the advantages of being easy to operate, simple in route and the like.

The present disclosure relates to a process for the preparation of Lranilanol, the process comprising reacting N-(4-chloro-2-iodophenyl)-1, 3-benzothiazole-6-sulfonamide with 5-hexynoic acid in the presence of a palladium catalyst and a copper salt.

The present disclosure relates to a process for manufacturing lanifibranor which comprises reacting N-(4-chloro-2-iodo-phenyl)-1,3-benzothiazole-6-sulfonamide with 5-hexynoic acid in the presence of a Palladium catalyst and a copper salt.

The invention discloses a preparation method of a vibeglycolone intermediate, and belongs to the technical field of medicinal chemistry. Starting from 5-hexynoic acid, a target compound is obtained through five steps of reactions (amide condensation, Grignard reagent carbonylation, carbonyl alpha-position bromination, nucleophilic substitution and amino deprotection and protection), and the yield is as high as 72%. The route is high in synthesis efficiency and safety, avoids the use of oxidants and highly toxic products, reduces the harmless post-treatment cost, provides new technical reserve for the synthesis of vibeglycolone, and is more suitable for industrial application.

The application discloses a method for continuously synthesizing cis-13-octadecenal based on a micro-channel reactor, and belongs to organic synthesis. The method comprises unilateral bromination, acetylene coupling, selective hydrogenation, oxidation and purification. The method uses dodecanediol and 1-hexyne as raw materials, forms a method for continuously synthesizing cis-13-octadecenal, a key component of insect sex pheromone, in a high-efficiency and high-selectivity manner by using a micro-channel reactor, and effectively solves the problems of low cis selectivity, poor reaction efficiency and incapability of amplification effect in the synthesis of cis-13-octadecenal in the prior art.

The present disclosure relates to a process for the preparation of a compound of formula (I), said process comprising a palladium-free coupling reaction between N-(4-chloro-2-iodo-phenyl)-1, 3-benzothiazole-6-sulfonamide and methyl 5-hexynoate in the presence of a copper catalyst. (I)

The invention discloses an acidizing corrosion inhibitor for an oil and gas field and a preparation method of the acidizing corrosion inhibitor, and belongs to the technical field of CO2 oil displacement corrosion inhibition. The corrosion inhibitor comprises the following components: a cellulose-based imidazoline copolymer, tween-80, hexynol and a solvent consisting of water, ethanol and isopropanol. Dialdehyde cellulose is prepared through sodium periodate oxidation, oleic acid imidazoline prepared from oleic acid and tetraethylenepentamine is grafted into a cellulose molecular chain through Schiff base reaction, phosphoric acid esterification modification of hydroxyl at the C6 position of cellulose is achieved through phosphorus trichloride steam bath, the Schiff base reaction is utilized again, and the hydroxyl at the C6 position of cellulose is obtained. Grafting a terminal tertiary amino group to a dialdehyde cellulose molecular chain, and quaternizing through methyl iodide to obtain quaternary ammonium salt; three functional groups are connected to a cellulose molecular chain through chemical bonds, traditional physical mixing is replaced, and the long-acting stability of the corrosion inhibitor is improved. The corrosion inhibitor prepared by the invention has good slow-release effect and long-acting slow-release property, and can be used in the acidification process of oil and gas fields.

The invention relates to the technical field of high polymer materials, and discloses a crosslinkable polyethylene composition, a crosslinkable polyethylene material as well as a preparation method and application of the crosslinkable polyethylene composition and the crosslinkable polyethylene material. The crosslinkable polyethylene composition contains low-density polyethylene, an antioxidant, a peroxide additive and aliphatic mercaptan, relative to 100 parts by weight of low-density polyethylene, the content of the antioxidant is 0.1-0.5 part by weight, the content of the peroxide additive is 0.6-0.9 part by weight, and the content of the aliphatic mercaptan is 0.2-0.5 part by weight; wherein the peroxide additive is 2, 5-dimethyl-2, 5-bis (tert-butylperoxy) hexyne, and the peroxide additive is 2, 5-dimethyl-2, 5-bis (tert-butylperoxy And the aliphatic mercaptan is selected from at least one of C4-C16 straight-chain aliphatic mercaptans. The crosslinkable polyethylene material prepared from the crosslinkable polyethylene composition provided by the invention is excellent in scorching resistance, high in scorching safety, capable of being extruded for a long time in the processing process, small in byproduct generation amount, safe and environment-friendly.

The invention discloses three candidate antigen chimeric oligosaccharides of helicobacter pylori and a preparation method of the three candidate antigen chimeric oligosaccharides. A mannoheptalactone compound is subjected to triethyl orthoacetate protection of hydroxyl groups at the 2 and 3 positions, reduction of heterotopic positions, addition of alkyne olefine acid ester at the heterotopic positions, ring opening of triethyl orthoacetate and protection of hydroxyl groups at the 3 positions by acetyl to obtain a mannoheptase alkyne olefine acid ester donor, and the mannoheptalactone compound is subjected to three candidate antigen chimeric oligosaccharides of helicobacter pylori and the three candidate antigen chimeric oligosaccharides of helicobacter pylori. Then carrying out glycosylation reaction with 1-azidopropanol, and further reducing an azide group into an amino group; glucose thioglycoside is subjected to 6-site hydroxyl protection through a photosensitive protecting group, iodinated acrylic acid is added to 1-site, glucose thioglycoside is coupled with 1-hexyne to obtain a glucose alkyne olefine acid ester donor protected by the photosensitive protecting group, alpha-1, 6 connected glucooligosaccharide is prepared through a photosensitive one-pot method, then 6-site hydroxyl is protected through azidopropyl, and an azido group is reduced into amino; glutaric acid is used as a connecting arm to connect the two fragments, and the target chimeric oligosaccharide is finally obtained through three steps of propylidene removal, acetyl removal and hydrogenation deprotection. The preparation method is mild in condition and simple to operate.

The invention relates to the technical field of corrosion inhibitors, and provides a quinoline quaternary ammonium salt corrosion inhibitor and a preparation method thereof.The quinoline quaternary ammonium salt corrosion inhibitor is prepared from, by weight, 28-32 parts of quinoline quaternary ammonium salt, 2-4 parts of thiourea, 8-10 parts of organic phosphonic acid, 2-3 parts of alkynol, 2-5 parts of surfactant and 22-46 parts of solvent; the alkynol is propargyl alcohol, 2-hexyne-1-alcohol and N, N-dimethyl propargyl amine. By means of the technical scheme, the problem that in the prior art, a corrosion inhibitor is insufficient in corrosion inhibition effect at the high temperature is solved.