1 results about "Vinylacetic acid" patented technology

This invention belongs to the field of biochemical technology, specifically disclosing a 6′- O A whole-cell biosynthesis method for caffeoyl arbutin and its analogues includes the following steps: using aromatic carboxylic acids and vinyl acetates as substrates, performing a transvinylation reaction under palladium catalyst and base conditions to prepare aromatic vinyl esters; using the prepared aromatic vinyl esters as acyl donors, ... β Arbutin, using acyl acceptors, undergoes an aromatic acylation reaction in an organic solvent with whole cells of Aspergillus oryzae as a catalyst to yield the 6′- O Caffeoyl arbutin or its analogues. This invention develops a two-step whole-cell catalytic method for the efficient and sustainable synthesis of CA and its analogues. The synthesized compounds exhibit potent inhibitory activity against mushroom tyrosinase. This invention pioneers a novel green biosynthetic pathway for tyrosinase inhibitors, demonstrating significant application potential in the food preservation and cosmetics industries.