The invention discloses a hybrid five-axis laser cutting machine and relates to a laser cutting machine with a parallel and hybrid five-axis driving mechanism. The hybrid five-axis laser cutting machine has the characteristics of more flexible structure, larger rigidity, smaller inertia and higher precision and comprises a machine body, an X-direction guide rail, a cross beam, a laser cutting head and a controller, wherein a Y-direction guide rail is arranged on the side surface of the cross beam, and the laser cutting head is movably connected with the Y-direction guide rail on the side surface of the cross beam through a hybrid device; and the hybrid device comprises a Y supporting plate mechanism, a Z supporting plate mechanism, a driving frame, an annular support frame, a pair of driving block mechanisms and a pair of connecting rods. The five-axis motion of the conventional laser cutting head is realized through the hybrid device. As for the hybrid five-axis laser cutting machine, the concept is ingenious, all parts have flexible structures, the rigidity is great, the inertia is small and the motion precision can be further ensured. The laser cutting machine is a product formed by combining the machine tool technology, the robot technology and the numerical control technology, and compared with a traditional series machine tool, the laser cutting machine is simple in structure and is complex and accurate in mathematical operation. The laser cutting machine has the outstanding advantages of large rigidity, fast response, high precision, strong applicability, high technical added value and the like.