The embodiment of the invention discloses a hyperbaric oxygen chamber equipment operation monitoring method and system. The method comprises the steps that a hyperbaric oxygen chamber environmental oxygen index and a physical information index of a user are obtained, the control relationship is established between the environmental oxygen index and the physical information index, and when at leastone of the conditions that temperature detection data deviates from a body temperature early warning threshold value, pulse detection data deviates from a pulse early warning threshold value, blood pressure measurement data deviates from a blood pressure early warning threshold value, blood oxygen saturation data deviates from a blood oxygen early warning threshold value, and electrocardio data deviates from an electrocardio early warning threshold value is met, the environmental oxygen concentration, environmental oxygen pressure, environmental oxygen flow and environmental temperature are adjusted according to a concentration regulation step value, a pressure regulation step value, a flow regulation step value and a temperature regulation step value; deviations include greater or less than the early warning threshold value. Accordingly, by judging the oxygen pressure, concentration and flow in the hyperbaric oxygen chamber environment, equipment operation parameter real-time monitoring and feedback control is achieved, occurrence of dangerous accidents is avoided, the equipment operation is more efficient, and energy consumption is lowered.