The invention discloses an enzymatic degumming process based on immobilized compound phospholipase. The enzymatic degumming process comprises the following steps: A, preparing the immobilized compound phospholipase; B, applying the immobilized compound phospholipase to degumming of oils and fats, wherein the compound phospholipase contains phospholipase A1, phospholipase C, lipase and protease. According to the enzymatic degumming process based on the immobilized compound phospholipase, the phospholipase A1, the phospholipase C, the lipase and the protease which are used for degumming are immobilized on the same macroporous resin simultaneously firstly, then the macroporous resin immobilized with the phospholipase A1, the phospholipase C, the lipase and the protease is used for degumming the oils and fats, the phospholipase A1, the phospholipase C, the lipase and the protease play a synergistic role to degum the oils and fats, so that the immobilized compound phospholipase can be used repeatedly for degumming, enzyme residues are avoided in the oils and fats, the degumming efficiency is high, and oil yield is high.