The invention belongs to the field of skin care products and relates to a pore refining cream containing deep-sea essence and a preparation method of the cream. The scream is prepared from raw materials as follows: glycerin, squalane, deep-sea roe extract, deep-sea water, deep-sea seaweed extract, oat beta-glucan, blackcurrant fruit, avocado oil, cucumbers, rose essential oil, a traditional Chinese medicine additive and sterilized water, wherein the traditional Chinese medicine additive is prepared from raw materials in parts by weight as follows: witch hazel, chamomile, plums, peach blossoms, tree peony bark, blue gum and aloes. The cream has high safety, is free of allergic reaction, is rich in biological essence ingredients of deep-sea fish in combination with other various herbaceous plant essence and traditional Chinese medicine ingredients, is refreshing in texture and silky when contacted with skin, has multiple skin care effects, is infused into the skin to supplement water, improves the glossiness and compactness of the skin, refines pores and enables the skin to be tender and fine.