The invention discloses a composite fruit, vegetable and mixed cereal beverage for relieving male climacteric neurasthenia and a preparation method thereof, belonging to the field of functional beverage preparation. The composite fruit, vegetable and mixed cereal beverage comprises the following components in parts by weight: 2-5 parts of almonds, 3-4 parts of peanuts, 3-6 parts of Chenopodium quinoa willd, 2-4 parts of buckwheat, 0.5-1 part of lily, 2-3 parts of goji berries, 3-4 parts of black soybeans, 1-2 parts of walnut kernels, 7-12 parts of Chinese yam, 5-7 parts of Cleome gynandra, 3-6 parts of peas, 1-4 parts of corn, 3-4 parts of mulberry fruits, 7-9 parts of cherries, 12-14 parts of coconut juice and 4-5 parts of red dates. The invention also discloses the preparation method of the composite fruit, vegetable and mixed cereal beverage. The preparation method disclosed in the invention is simple and efficient, and various raw materials can be easily obtained, so that industrial generalization is facilitated. The product prepared in the invention has high sensory quality and strong and palatable flavor, is bright in color, and sweet and sour in taste, and can be drank for a long period as a daily beverage. In addition, the product has the health-care efficacy of relieving male climacteric neurasthenia and male climacteric mental and psychological discomfort, thereby having very high promotional value in the market.