The invention discloses a method for preparing high-performance fluorine-silicon modified finish-coat paint. The method is simple in process, low in manufacturing cost, safe, environment-friendly and suitable for industrial production. Fluorine-silicon modified acrylate serves as a main raw material and is excellent in film-forming property, high in adhesive force and excellent in hydrophobic property; epoxy silane modified silica sol is capable of improving the film surface performance and excellent in dispersity and realizes film surface performance uniformity; due to the addition of graphene oxide, the adhesive force, flexibility, impact resistance, water resistance, salt fog resistance and hardness of the finish-coat paint can be greatly improved; the antibacterial mildew preventive adopts traditional Chinese herbal medicine extract and is safe, environment-friendly, non-toxic and excellent in antibacterial property; the stain-resistant assistant contributes to improving the stain resistance of the finish-coat paint film; and the finish-coat paint disclosed by the invention has the adhesive force reaching the level 2, has a static contact angle of 110-120 degrees between the coating and water, has good flexibility and impact resistance and excellent hydrophobic property, water resistance, salt fog resistance and stain resistance, does not contain any volatile organic compound and is safe, environment-friendly, antibacterial, mildew-proof and long in service life.