51 results about "Promethazine Hydrochloride" patented technology

The invention belongs to the field of medicine preparation, and in particular relates to a promethazine hydrochloride tablet and a preparation method thereof. The preparation method comprises the following steps: firstly, weighing poloxamer and PEG6000 to prepare an auxiliary solution, further preparing a main medicine solution from an effective component promethazine hydrochloride, and uniformly mixing the auxiliary solution and the main medicine solution, thereby obtaining a mixed solution; performing vacuum drying on the mixed solution; crushing the obtained solid material, adding other excipient, putting into a granulator for shearing and granulation, and putting into a boiling dryer for drying; screening and shaping the dried granules, mixing the obtained granules and a lubricant of the formula, and subsequently tabletting.

The invention relates to the technical field of preparation and application of capillary electrochromatography monolithic columns, and discloses preparation and application of a bis[-6-N-(imidazolyl-2-amino-propionic acid-3-)]-beta-CD (beta-CD-E2) capillary electrochromatography (CEC) monolithic column; the CEC column is prepared from beta-CD-E2, and enantiomers of chiral substances can be split.The preparation comprises the steps: 1, constructing a chiral environment by beta-CD-E2, preparing a unique chiral CEC column from beta-CD-E2, a secondary functional monomer and the like, and applyingthe unique chiral CEC column to efficient capillary electrophoresis; 2, searching the optimal formula and conditions through proper characterization means, and optimizing the method and conditions; and 3, preparing a chiral CEC column detachable chiral compound from the prepared beta-CD-E2 with an acid-base amphoteric group, and establishing four receptor antagonists, namely terazosin hydrochloride (TER), promethazine hydrochloride (PMZ), doxazosin mesylate (DOX) and hydroxypropyl piperazine (DROP), two herbicides, namely imazethapyr (IMZR) and imazethapyr (IMZC) and other chiral compounds. The invention discloses an enantiomer resolution and qualitative and quantitative analysis method.

The invention relates to a compound dibazole and hydrochlorothiazidum capsule and process for preparation, wherein the raw materials include dibazole, promethazine, chloroquine phosphate, guanoxan sulfate, vitamin B6, potassium chloride, crystoserpine, hydrochlorothiazidum, calcium lactate, vitamin B1, magnesium trisilicate and medicinal starch. The end product can effectively lower blood pressure.

The invention relates to an oral medicine for treating asthma, and a preparation method thereof, and aims to solve problems that traditional Chinese medicine takes effect slowly while the curative effect of western medicine can not meet patients' satisfaction. The oral medicine is prepared by raw drug materials according to the following weight ratio: 150-300 of pheretima, 2.5-5 of promethazine hydrochloride, 20-50 of radix asteris, 50-100 of white ammonium chloride, 20-50 of radix stemonae, 56-112 of extractum glycyrrhizae, 1-2 of camphor and 1-2 of star anise oil. The preparation method comprises the following steps of (1) smashing a specified amount of pheretima, promethazine hydrochloride, radix asteris, white ammonium chloride, radix stemonae, and camphor into fine powder respectively; and (2) mixing the smashed raw drug materials with a specified amount of extractum glycyrrhizae and star anise oil thoroughly, and making into tablets, pulvis and capsules or other oral preparations. The oral medicine has the functions of relieving asthma, tranquilization, moistening lung to relive cough and resisting allergy, can be used for treating bronchitis, emphysema and asthma, takes effect quickly, and has high cure rate.

The invention discloses a medicine for treating rhinitis. The medicine consists of honeycombs and radix angelicae, wherein at least one traditional Chinese medicine can be added: flos magnolia, angelica sinensis, radix bupleuri, fried gardenia, radix scrophulariae, fritillaria and at least one of the following western medicines: cetirizine hydrochloride, promethazine hydrochloride and azelastine hydrochloride. The invention further discloses a production process of the medicine for treating rhinitis. The process comprises the following steps: (1) crushing raw materials; (2) adding other traditional Chinese medicines or / western medicines; and (3) preparing pills or capsules by mixed dust. The invention further discloses a production process of the medicine for treating rhinitis. The process comprises the following steps: (1) decocting the honeycombs and radix angelicae with water; (2) adding other traditional Chinese medicines or / western medicines; (3) filtering; and (4) adding propolis and beta-cyclodextrin to prepare a water decoction, an oral solution or an electuary. The medicine disclosed by the invention is good in curative effect, easily available in material, low in cost and high in utilization ratio of nutritional value.

A pharmaceutical composition for treating hypertension and a preparation method thereof. A compound reserpine tablet is provided, the tablet includes reserpine, hydrochlorothiazide, vitamin B6, vitamin B1, calcium pantothenate, magnesium trisilicate, potassium chloride, dihydralazine sulfate, promethazine hydrochloride And a pharmaceutically acceptable carrier, wherein the vitamin B1 exists in the form of coated granules.

The invention belongs to the technical fields of medicines and medicine production, and in particular relates to a promethazine hydrochloride tablet and a preparation method thereof. On the basis of selecting related adjuvants and carriers, the tablet, by combining stevioside and promethazine hydrochloride, is quite ideal in formability and disintegrating performance; and meanwhile, a formula is also further simplified.

The invention discloses a method for determining the dissolution rate of five components in compound reserpine tablets through ultra-performance liquid chromatography, and relates to the field of analytic chemistry. The method comprises the steps that gradient elution is performed on a mobile phase composed of a mobile phase A and a mobile phase B; the mobile phase A is a water solution containinghexanesulfonate, wherein the concentration of the hexanesulfonate is 0.05-0.1%, and pH is 2.5-3.0; the mobile phase B is a mixing solution of methyl alcohol and acetonitrile, and the volume ratio ofmethyl alcohol to acetonitrile is (4.5-5.5):1; peaks can be effectively separated out from the five components of vitamin B1, vitamin B6, hydrochlorothiazide, dihydralazine sulfate and promethazine hydrochloride in the compound reserpine tablets, the number of theoretical plates and the separation degree meet the requirements, the separation effect is obvious, and the dissolution rate of five components in compound reserpine tablets can be determined; the method has the advantages of being simple, rapid, high in sensitivity, good in selectivity and the like.

The invention relates to a medicinal composition for treating phlegm and relieving cough, and in particular relates to a high-stability compound potassium guaiacolsulfonate oral solution and a preparation method thereof. The composition comprises the following components: potassium guaiacolsulfonate, promethazine hydrochloride, ammonium chloride, citric acid, sodium citrate, xylitol, benzoic acid, an antioxidant, a pH regulator and propylene glycol and purified water as solvents. The compound potassium guaiacolsulfonate oral solution prepared by the method has the advantages of high stability during storage process, low tendency to crystallization, long validity period and the like, and effectively ensures the quality of a medicine and the safety of patient's medication.