56 results about "Serous membrane" patented technology

The present invention involves new interventional methods and devices for reconfiguring a portion of the gastrointestinal tract. The procedures are generally performed laparoscopically and may generally be described as laparoscopic plication gastroplasty (LPG) in which, after obtaining abdominal access, spaced apart sites on a gastric wall are engaged, approximated and fastened to create one or more tissue folds forming one or more plications projecting into the gastrointestinal space. The serosal tissue may optionally be treated during the procedure to promote the formation of a strong serosa-to-serosa bond that ensures the long-term stability of the tissue plication. These procedures are preferably carried out entirely extragastrically (i.e. without penetrating through the gastrointestinal wall), thereby minimizing the risks of serious complications.

The present invention involves new interventional methods and devices for reducing gastric volume, and thereby treating obesity. The procedures are generally performed laparoscopically and may generally be described as laparoscopic plication gastroplasty (LPG) in which, after obtaining abdominal access, spaced apart sites on a gastric wall are engaged and approximated to create one or more tissue folds that are then secured by placing one or more tissue fasteners to produce one or more plications projecting into the gastrointestinal space. The serosal tissue may optionally be treated during the procedure to promote the formation of a strong serosa-to-serosa bond that ensures the long-term stability of the tissue plication. These procedures are preferably carried out entirely extragastrically (i.e. without penetrating through the gastrointestinal wall), thereby minimizing the risks of serious complications. Minimally invasive devices for approximating and fastening soft tissues are disclosed that enable these new interventional methods to be carried out safely, efficiently and quickly. Methods for reversing the procedure are also disclosed.

The invention discloses a preparation method of a textile waterproofing agent, and belongs to the field of textile waterproofing materials. Nano-silica is modified by coupling agents, owing to small size effects and macroscopic quantum tunneling effects of the nano-silica, fiber breakage can be effectively prevented, the abrasion resistance of a serous membrane is improved, the dispersibility of the nano-silica can be improved, and mallow bark extracting solution is adsorbed by the adsorption performance of the nano-silica. As extracting solution molecules contain much -OH and enter a weave structure of a silk fabric, fibers generate good cohesiveness, and the tensile property and the ultraviolet resistance of the fabric are improved. The preparation method solves the problems of low tensile property and fiber breakage of fabrics due to the fact that waterproofing agents in the present market cannot effectively prevent water.

Described are purified extracellular matrix materials isolated from the abdominal wall of animals and including the subserous fascia layer of the abdominal wall. Such medical materials can find use in treating damaged tissue and in certain aspects in providing tissue support for the repair of hernias. Related methods of manufacture and use are also described.

A percutaneous ostomy implant for implantation into the abdominal wall of a patient is provided, which includes a connecting member for mounting an external detachable device thereto; a first tubular ingrowth member depending from the connecting member; and a second tubular ingrowth member depending from the connecting member and being radially outwardly spaced from the first tubular ingrowth member. The first tubular ingrowth member is configured and dimensioned to receive a bowel segment within it to allow the stoma and serosal tissue of that bowel segment to infiltrate the first tubular ingrowth member. The second tubular member is configured and dimensioned to abut dermal tissue to allow the dermal tissue to infiltrate the second tubular ingrowth member, thereby securing and sealing the ostomy implant to the dermis.

The invention discloses a method for spinning poplin fabric, and manufactured poplin fabric; the specification of the fabric manufactured by adopting purified cotton yarn weaving is: the poplin fabric with the blended fabric ratio of 70 percent of three-level cotton, 30 percent of long stapled cotton, the warp and weft density of 120 multiplied by 80 per inch, fabric weave of small jacquard design, and 118 inches of fabric width. As the invention adopts a special technical method in the working procedures of warping, slashing and weaving, and the like, the quality of the product is guaranteed, thus significantly improving the quality and the grade of the product. Besides, the beneficial effect of the invention lie in that the end breakage rate in the weaving process is lowered; braid yarn is reduced; serous membrane strength is high; wear resistance is good; filoplume paste rate is high; and the poplin fabric manufactured by weaving has neat and well-placed cloth cover, smooth and bright surface, clear grain, soft texture, high resilience, and strong feeling of silk.

The invention discloses a high-flexibility stitch closure line and a production technology thereof. In a stitch closure line production process, an antibacterial agent is prepared and is prepared in away that chitosan is taken as a carrier to carry an intermediate 5; when the stitch closure line is used for suturing a wound, cells on the wound can absorb carboxymethyl cellulose on a micro-capsule, and the micro-capsule disintegrates to release collagen and the antibacterial agent; the antibacterial agent is of a gel form and can be attached to the surface of the wound, so that the intermediate 5 can be released and acts on bacteria DNA gyrase, and DNA duplication is disturbed to cause bacteria to die; and meanwhile, the intermediate 5 can break a cell serous membrane, bacteria content runs off to cause the bacteria to die, so that a wound suturing part is free from bacteria infection, wound healing speed is improved, in addition, the stitch closure line has good flexibility, and the wound can be easily recovered.

The invention relates to a soft tissue repair material and a method for preparing the same, and belongs to the technical field of biomedical material processing. The method includes steps of 1), removing small intestine mucous membranes, muscular layers and serous membranes on small intestine tissues of mammals and carrying out washing by the aid of sterile buffer solution with antibiotics by 3-5times to obtain washed lower-layer tissues of the small intestine mucous membranes; 2), clipping the lower-layer tissues to obtain sections, and splitting and spreading the sections along median linesto obtain pretreated lower-layer tissues of the small intestine mucous membranes; 3), placing the pretreated lower-layer tissues in sterile buffer solution with surfactants and nuclease and carryingout oscillation treatment at the temperatures of 37 DEG C for 1-4 h to obtain acellular lower-layer tissues of the small intestine mucous membranes; 4), carrying out oscillation cleaning, cutting anddrying to obtain dried central basement membranes; 5), carrying out irradiation sterilization to obtain the soft tissue repair material. The soft tissue repair material and the method have the advantage that the safe and effective soft tissue repair material with excellent bioactivity and biocompatibility can be prepared by the aid of the method.

Disclosed is a cell wall destroyed roe plasm and its production process whose main constituents include fish roes undergone cell wall breaking and auxiliary material for flavoring, its preparing process comprises the steps of choosing fish egg cell as raw material, removing serous membrane and ribs, rinsing, carrying out enzymolysis with H2O2 enzyme, controlling the temperature within the range of 37-40 deg C., adjusting pH to alkalescence (microscope detected wall breaking ratio>90% ), tissue cell triturating, deactivating, loading, Pasteurising decontamination, and cooling down to obtain the finished product.

The invention relates to a biological periosteum repair material and a preparation method thereof, and particularly relates to an acellular dermis matrix material and a preparation method and application thereof to periosteum repair. The preparation method comprises: (1) taking a jejunum segment of a pig small intestine, cleaning up, radially cutting open, removing a mucous layer, a myolemma layerand a serosal layer and obtaining a pig small-intestine mucous lower-layer tissue membrane; (2) sequentially carrying out the following processing on the obtained pig small-intestine mucous lower-layer tissue membrane: firstly, placing in peracetic acid solution to soak and cleaning up; then placing in sodium hydroxide solution to soak and cleaning up; finally, placing in acetone solution to soak, cleaning and obtaining a pig small-intestine mucous lower-layer tissue acellular matrix. The biological periosteum repair material is high in biological safety, low in immunogenicity and cytotoxicity, good in biocompatibility, can promote multiplication of cells adhered to the biological periosteum repair material, is applicable to use as a biological repair material and is particularly suitablefor periosteum repair.

The invention provides a method for preparing a natural tubular small intestine acellular matrix membrane and belongs to the technical field of medical biological materials. The method comprises the following steps: cleaning small intestines cut from animals; adding the cleaned small intestines into a closed container, rapidly freezing in liquid nitrogen at the temperature of 80 DEG C below zero,taking out within half an hour, unfreezing, sleeving on an annular tubular scaffold, destroying the serosa by scissors, cutting off the serosa of the small intestines, scraping the destroyed serosa ofthe small intestines by organic glass, turning over the small intestines, scraping the mucous layer, submucosa and muscular layer of the small intestines, and removing the basal cells of the small intestines, thereby obtaining the single-layer tubular small intestine acellular matrix membrane; and performing freeze-dried seal and sterilizing preservation on the obtained single-layer and multilayer tubular small intestine acellular matrix membranes, thereby obtaining the natural tubular small intestine acellular matrix membranes of different thicknesses. The preparation method disclosed by theinvention is simple, and the prepared small intestine acellular matrix membrane is natural tubular.

The invention discloses a removal process of intestinal tissues, barring casings, and ultrasonic transducer special for the removal process, which are mainly used for removing serosal layers, muscular layers and upper mucosal layers of intestines and attaching tissues such as fat, fascia and the like. The removal process includes: defining lower mucosal layers of the intestines as outermost layers; suck-drying the surface of each outermost layer; stretching the outermost layers tight on a fixing stick; closing an upper hemispherical head and a lower hemispherical head of a special noninvasive ultrasonic cavitation machine; irradiating the intestines by noninvasive ultrasound; and taking down and washing the intestines with water. The removal process is helpful for quickly removing intestinal tissues, barring casings, so as to obtain light, thin and transparent casings in good color. The removal process has the other advantage that implementing large-scale production by ultrasound improves production efficiency and promotes industrial development.

The invention provides a gastric cancer surgical instrument, which comprises a gastroscope and a laparoscope, wherein the gastroscope comprises a gastroscope illuminating lamp, a gastroscope indicatorand a gastroscope camera, the gastroscope illuminating lamp is used for illuminating a local area, the gastroscope indicator is provided with a point light source, and is used for prompting the position of a stomach tumor, the gastroscope camera is used for transmitting an image, and the laparoscope is used for observing stomach tumors. By arranging the gastroscope indicator, a point light sourceemitted by the gastroscope indicator can penetrate through the gastric wall from the inside of the stomach to form a clear bright spot on the serosa layer of the stomach, the bright spot can be clearly observed in the visual field of the laparoscope, and the point light source is selected to improve the penetrating power and the irradiation precision of light, so that the stomach cancer surgicalinstrument can improve the accuracy of prompting the position of the stomach tumor.

The invention discloses a middle ear anti-adhesion membrane and a preparation method thereof, and the middle ear anti-adhesion membrane comprises a central support base material, an adhesive and an antibiotic layer which are uniformly coated on two sides of the central support base material, and an outer polylactic acid-glycolic acid copolymer membrane which is adhered outside the adhesive and the antibiotic layer, wherein antibiotics are loaded on the surface of the polylactic acid-glycolic acid copolymer membrane. The ear anti-adhesion membrane is properly cut according to the specific condition of a patient during clinical use, injured tissue can be isolated from normal serous membranes, the situation that new tissue adheres to other surrounding normal serous membranes in the healing process of a wound is avoided, the ear anti-adhesion membrane can play a role in replacing the eardrum of the patient to transmit sound to a certain extent, and the problem of secondary injury caused by implantation of the cartilage tissue is avoided.

Device and method for selectively ablating a submucosal layer of a duodenal wall and/or of sensory neurons therein, including a laser transmitting element coupled with the catheter body and configured to transmit a laser beam having a spot diameter of less than 200 microns and to provide an ablative dose of 0.5-2.5 J/mm; wherein the laser beam is configured to selectively ablate an area of the submucosal layer that is at least twice the size of the spot diameter, while essentially preventing damage of the surrounding mucosal, muscularis and/or serosal layers of the duodenal wall; and an expandable member configured to stretch the duodenal wall and to generate a fixed distance between the catheter's laser transmitting element and the duodenal wall.

A new method for the treatment of ocular disease and injury are provided.

The methods involve the administration of a biocompatible implant, the porcine small intestinal serosa (or serous membrane), as graft/patch directly to the eye, for inducing restoration, remodeling, and repair of a tissue in a variety of injuries or conditions in the cornea, conjunctiva, and/or the eyelid due to trauma, diseases, or surgery.

A focus on graft interactions, safety profile has been fully defined and the membrane is reasonable in process, easy and convenient to prepare and significant in therapeutic effect.

A simple standardized and straightforward method it has been developed to fabricate this ultra-thin, delicate, and transparent material.

Derived from well-defined mechanical strength, the graft demonstrates consistency and flexibility than provides agile solutions for the Physician.

The invention provides a starch textile sizing agent for replacing PVA (polyvinyl alcohol). The starch textile sizing agent is prepared from, by weight, 20-32 parts of composite modified starch, 8-15 parts of polyacrylate emulsion, 1-3 parts of defoaming agents and 100 parts of deionized water. The polyacrylate emulsion mainly comprises acrylic acid, vinyl acetate, butyl methacrylate and maleic acid which are polymerized. The starch textile sizing agent has the advantages that serous membranes obtained under the synergistic effects of various components in the starch textile sizing agent are high in elasticity and elongation, serous fluid is high in stability, methods for preparing the starch textile sizing agent are simple, and the starch textile sizing agent is suitable for industrial application.