The invention discloses a low-nitrogen combustion transformation method and system of a medium-grade kiln, and belongs to the technical field of low-nitrogen combustion. The transformation method comprises the following steps: dismounting a coal burning device, arranging two fuel gas inlets, introducing natural gas, air and circulating flue gas into the head fuel gas inlet, and introducing air into the middle fuel gas inlet. The system comprises a medium-grade kiln, a natural gas pipeline, an air header pipe, a head air pipeline, a middle air pipeline, a flue gas circulating pipeline, a steam pipeline, a mixer I, an air blower, a filter, a mixer II, an induced draft fan and the like. Circulating flue gas is introduced into the head fuel gas inlet to inhibit combustion, so that insufficient combustion is performed at the front end of the middle-grade kiln, and then air is introduced into the middle fuel gas inlet to promote sufficient combustion at the middle-rear end in the middle-grade kiln so as to promote carbon monoxide to generate carbon dioxide, so that the emission amount of nitrogen oxide is reduced. Compared with a common coal-to-gas technology, the emission of nitrogen oxides can be reduced by more than 35%.