54results about How to "Does not affect dissolution" patented technology

The invention relates to a voriconazole tablet, wherein the tablet core of the tablet comprises lactose hydrous, pregelatinized starch, croscarmellose sodium, povidone K90 and magnesium stearate. The prepared tablet core can reach higher hardness, is low in friability, facilitates coating, and can maintain the physical form during packaging and transport process; and although the hardness of the tablet core is higher, the dissolution rate of the tablet is not influenced, and the tablet can be disintegrated within about 20 minutes or a shorter time.

The present invention relates to a kind of oral trimebutine tablet and its preparation method. Said invention is characterized by that the trimebutine raw material can be coated with water soluble film-forming agent and plasticizer. The tablet made up by said method can hide the taste of trimebutine, at the same time it does not affect disintegration and does not affect resolution of its main component.

The present invention discloses a silurus asotus feed phagostimulant and a preparation method thereof, and belongs to the technical field of feed additive preparations. Based on nutritional requirements of silurus asotus and water body environment, and combining food intake characteristics, a formula of raw materials is optimized. The silurus asotus feed phagostimulant scientifically combines compound flavor peptides greatly improving palatability and feed utilization rate, having a relatively strong anti-oxidation effect and eliminating free radicals; an accharomyces cerevisiae culture having functional characteristics of being strong in nutrition, biological activity, oxidation resistance, etc.; a high-calcium cerasus humilis extract effectively supplementing calcium, iron and soluble fibers, having a strong embedding effect and prolonging a shelf life; artemisia carvifolia seed powder significantly improving antifreeze effects and stability, improving water resistance and gloss, and enhancing and promoting palatability; and wheat malt powder providing rich nutrients, bioactive substances and plant enzyme sources. Finally, the prepared silurus asotus feed phagostimulant is strong in phagostimulant and good in production performances.

The invention relates to a processing method of a Pleioblastus amarus tea, and belongs to the technical field of Pleioblastus amarus processing. The processing method comprises the following steps: 1, carefully choosing a Pleioblastus amarus raw material; 2, cleaning and shelling; 3, scalding; 4, dicing; 5, lyophilizing; 6, roasting; 7, cooling; 8, sorting; and 9, packaging. The Pleioblastus amarus tea is suitable for most people, is convenient, and can be added with water to obtain a tea for drinking; and sugar or honey can be added to the Pleioblastus amarus tea when drunk, has no influences on the dissolve-out of substances, and has no influences on the health function characteristic of the Pleioblastus amarus tea. The Pleioblastus amarus tea has a slight bitter soup, a delicate fragrance and a tasty taste, has the medical efficacies of digestion promoting, heat clearing, vexation eliminating, fatigue eliminating, humidity eliminating, water retention alleviating, blood vessel protecting, ageing resisting, tumor resisting, lipid lowering, fat reducing and the like, and has the effects of bacteriostasis, anti-virus, anti-oxidation and radiation resistance.

The invention discloses a sprouting whole grain with high sprouting rate and a preparation method of the sprouting whole grain, belonging to the technical field of deep processing of grains. A soaking process is subjected to ultrasonic cleaning, as well as high-pressure pulsed electric field treatment or biological enzymolysis or the combination of the high-pressure pulsed electric field treatment and the biological enzymolysis, and a manner of soaking and sprouting in different stages is adopted, so that the sensing quality and the sprouting yield and quality of the sprouting whole grain product are improved, and the sprouting loss is reduced. The preparation method is simple, the temperature for soaking and sprouting is low, and the period is short, so that energy source is saved, and the preparation method is environment-friendly. The contents of functional, nutritious and biological active substances in the sprouting whole grain product as well as the food safety are significantly improved. For example, in sprouting coarse rice prepared through the preparation method disclosed in the invention, the content of gamma-aminobutyric acid is 303.8-312.6 mg/100g, the content of glutathione is 16.8-18.3 mg/100g, the content of inositol pexaphosphate (IP6) is 460.8-484.4 mg/100g, and the content of dietary fiber is 3.5-3.6 mg/100g.

The invention relates to a tenofovir disoproxil fumarate oral tablet and a preparation method thereof. Normal-temperature solution (10-30DEG C) is adopted for preparing pregelatinized starch to serve as an adhesive. The pregelatinized starch in a suspension state is capable of wrapping raw materials to some extent to prevent gathering of the raw materials, gelatinization of pregelatinized starch suspension prepared at the normal temperature is avoided, a disintegration function of the starch is reserved, and since an adhesive action is limited, influences on dissolution due to overlarge particle hardness is avoided. Consumption of auxiliary materials is reduced on the basis of keeping similar dissolubility to existing tablets, total tablet weight can be reduced by 20-40% approximately, tablet size is greatly reduced, and accordingly difficulty in swallowing is lowered, and patients can take the tablet more easily.

The invention relates to the technical field of a pesticide and particularly relates to a herbicide containing glyphosate and dicamba and a preparation method thereof. The herbicide is prepared from the following raw materials in parts by weight: 40-65 parts of glyphosate, 15-25 parts of dicamba, 27-48 parts of alkaline substances, 2-5 parts of a surface active agent and 0-5 parts of inorganic filler. Verified by experiments, when the mass ratio of the glyphosate to the dicamba is 3 to 1, the optimal synergistic effect can be generated; by selection of proper surface active agent and proper used amount, the pesticide effect is obviously improved; verified by experiments, N-polyoxyethylated-N-tallow-alkylamine or alkyl polyglucoside is selected as the surface active agent, and when the weight part of N-polyoxyethylated-N-tallow-alkylamine or alkyl polyglucoside is 5, the obvious synergistic effect can be achieved, the foaming property is not more than 20mL, and the dissolution of a preparation cannot be influenced; and in addition, the invention also provides a preparation method of the herbicide. In preparation, a solid-solid synthesis process is adopted, the production efficiency is improved, the production cost is saved and the energy consumption is reduced.

The invention discloses a high-yield catfish feed attractant and a preparation method thereof and belongs to the technical field of feed additive preparation. The high-yield catfish feed attractant and the preparation method thereof have the advantages that the nutritional requirements of catfish and water environments are combined with the ingestion features of the catfish to optimize a raw material formula, raw materials are scientifically compounded to greatly increase palatability and feed utilization rate, and the attractant comprises compound flavor peptide which has high anti-oxidation effect and is capable of removing free radicals; the high-yield catfish feed attractant contains saccharomyces cerevisiae culture with functional features such as high nutrition, high bioactivity and high oxidation resistance, Prunus Humilis Bunge extract which can effectively supplement calcium, iron and soluble fibers, has a powerful embedding effect and can prolong shelf life, wormwood seed powder which can evidently increase an anti-freezing effect and stability, increase water resistance and glossiness, enhance and promote palatability and lower powder content, and wheat malt powder which can provide rich nutritional substances, bioactive substances, fragrant substances and plant enzyme sources; the prepared high-yield catfish feed attractant is high in palpability and good in production performance.

The invention discloses a sprouted whole grain with strong inoxidizability and a preparation method for the sprouted whole grain, and belongs to the technical field of grain deep processing. Ultrasonic cleaning is conducted in the soaking process, a high voltage pulse electric field, biological enzymolysis, or combination of the high voltage pulse electric field and the biological enzymolysis is adopted for treatment, a segmented soaking and sprouting manner is adopted for sprouting, the sensory quality, the sprouting yield and quality of the sprouted whole grain are improved, and the sprouting loss is reduced. The preparation method is simple, the soaking and sprouting temperature is low, the period is short, the energy is saved, environment can be protected, the content of functional, nutritional and bioactive materials in the sprouted whole grain is obviously increased, and the food safety is obviously improved. Husked rice can be taken as an example, and according to the sprouted husked rice prepared by the method, the content of gamma-aminobutyric acid is 303.8-312.6 mg/100 g, the content of glutathione is 16.8-18.3 mg/100g, the content of inositol hexaphosphate (IP6) is 460.8-484.4 mg/100 g, and the content of dietary fiber is 3.5-3.6 mg/100g.

The invention provides a method for preparing Tiopronin enteric-coated tablet. The method comprises the steps of preparing Tiopronin tablet, tablet wrapping isolation clothes, wrapping enteric coating and the like. The Tiopronin enteric-coated tablet produced according to the method of the invention features simple technique and low cost, and can effectively cover the odor of Tiopronin.

The invention discloses sprouted whole grain with a long quality guarantee period and a preparation method of the sprouted whole grain, and belongs to the technical field of deep processing of grain. Ultrasonic cleaning is performed on a soaking process, a high voltage pulse electric field, biological enzymolysis or combination of the high voltage pulse electric field and the biological enzymolysis is performed, a sectional soaking and sprouting manner is adopted for sprouting, so that the sensory quality, the sprouting yield and the sprouting quality of a sprouted whole grain product are improved, and the sprouting loss is reduced. The preparation method disclosed by the invention is simple, soaking temperature and sprouting temperature are low, soaking period and sprouting period are short, energy resources are saved, the preparation method is environmentally friendly; contents and food safety of functional substances, nutritional substances and biological activity substances in the sprouted whole grain product are observably increased and improved; brown rice is taken as an example, the content of gamma-aminobutyric acid of sprouted brown rice prepared by the preparation method disclosed by the invention is 303.8-312.6mg/100g, the content of glutathione is 16.8-18.3mg/100g, the content of Inositol Hexaphosphate(IP6) is 460.8-484.4mg/100g, and the content of dietary fibers is 3.5-3.6mg/100g.

The invention discloses Argentine cream pumpkin powder. The Argentine cream pumpkin which is rich in microelement cobalt and pectin is taken as a raw material, by-products, including pumpkin seeds, pumpkin leaves and pumpkin bee pollen, in deep processing of the pumpkin are fully used as raw materials, a low-temperature processing technique is adopted in the whole process, and any essences, spices, food additives or chemical substances are not added, so that natural flavor, quality and taste of the pumpkin are extremely maintained, and the food safety and extraction efficiency of the pumpkin powder ingredient materials are effectively promoted; various functional extracts are scientifically compounded and synergistically act, so that the nutrition, functionality, instant dissolving property, liquidity, healthcare effect and guarantee period of the pumpkin powder are obviously enhanced; a new efficient method is developed for pumpkin planting and deep processing; the economic income of farmer households is increased; the problem of environmental pollution caused by abandoned by-products is solved; the issues of agriculture are effectively solved; and the Argentine cream pumpkin powder has certain economic and social values.

The invention discloses a processing process of blackberry-flavored breakfast biscuits. The processing process includes the following steps: firstly, all raw materials are weighed in parts by weight;secondly, wheat flour, palm oil and bean dreg powder are evenly mixed, pure water and half of blackberry juice are added, concocting is conducted to form a dough, honey is added, then table salt and carbon baking soda are added, stirring is conducted until the dough is even and fine, fermentation is conducted for 2-3 h, and a fermented dough is obtained; thirdly, forming is conducted by a biscuitcompression forming device; and fourthly, baking is conducted. The bean dreg powder replaces part of the wheat flour, thus digestion of the biscuits can be delayed, aging of starch is delayed, and theshelf life of the biscuits is prolonged; the even blackberry taste is obtained by blending the blackberry juice, and the biscuits have the nutrients from blackberries; through the specially-made biscuit compression forming device, the wanted complete biscuit shape can be obtained, and the density degree and the taste of the biscuits can be controlled; and the breakfast biscuits which are rich innutrition, beneficial to intestinal health and long in shelf life are obtained.

The invention discloses cefradine capsules and a preparation method thereof. The capsules consist of filler and capsule shells, wherein the filler is obtained by mixing medicament-containing fine powder and a lubricating agent uniformly, and the medicament-containing fine powder is prepared from cefradine, Span and neutral inorganic salt. The preparation method comprises the following steps of: adding the cefradine into the Span, stirring uniformly, then adding the inorganic salt, performing adsorption to obtain the medicament-containing fine powder, mixing the medicament-containing fine powder and the lubricating agent, and filling the capsule shells with the mixture. The capsules have the advantages of high stability and quick dissolution, meanwhile, the preparation method is simple and meets the requirement of mass production.

The invention discloses a high-digestion high-utilization-rate catfish feed, and belongs to the technical field of processing of catfish feeds. Based on nutritional requirements of catfish and water body environment, the digestion characteristics of the catfish are combined, the formula of a conventional catfish feed is optimized, and a feed complex enzyme, wormwood seed powder, a prunus humilis bunge extract and a phagostimulant are scientifically compounded, so that the catfish feed can be prepared, wherein the feed complex enzyme can effectively degrade anti-nutritional factors in the catfish feed, increase the utilization rate of nutrient substances of starch, protein, minerals and the like, increase the protein level, the organism antioxidative activity and the digestive absorption rate of the catfish, significantly increase the digestibility and the production properties of the catfish, reduce the feed coefficient, prevent the water bodies from being polluted and maintain good water quality is scientifically compounded; the wormwood seed powder can significantly improve the caking property, the water resistance, the glossiness and the frost resistance of the catfish feed and reduce the powder containing rate of the feed; the prunus humilis bunge extract can effectively complement calcium, ferrum and soluble fibers; the phagostimulant can substantially improve the palatability of the feed; and therefore, the catfish feed is good in feed coefficient, high in digestibility, good in production properties, high in propagation properties, high in disease resistance, high in palatability and low in cost.

The invention discloses azithromycin granules, which consist of the following components in parts by weight: 5-20 parts of azithromycin, 1.5-3.0 parts of sodium triphosphate, 0.4-0.6 parts of hydroxypropyl methyl cellulose, 0.8-1.2 parts of acesulfame, 0.8-1.2 parts of sweet orange taste essence, 80-95 parts of sugar and a proper amount of pure water. The invention also discloses a preparation method of the azithromycin granules. The conception is skilful, the mouthfeel of the medicament is effectively improved through a simple medicinal composition, an unexpected effect of covering the bitterness of the medicament is achieved, and dissolution of the medicament in vivo is not influenced. The preparation method has the advantages of simple process, no need of special equipment and low production cost.

The invention discloses a compound fertilizer anti-caking agent with a slow-release effect and compound fertilizer in which the compound fertilizer anti-caking agent added. The compound fertilizer anti-caking agent is prepared from 10 to 20% of surfactant, 20 to 30 % of thickening time control agent, 45 to 55% of hydrophobic agent and 5 to 10% of sustained release agent, wherein the thickening time control agent is at least one of stearic acid, magnesium stearate and palmitic acid; the hydrophobic agent is at least one of talc, activated clay and diatomaceous earth; the sustained release agent is isobutylidene-diurea. The compound fertilizer anti-caking agent with the slow release effect disclosed by the invention has the effect of preventing hardening by coating the surfaces of particles to form an interfacial membrane and isolating the contact of the surfaces of the particles so as to not form a salt bridge, thereby reducing the moisture absorption rate obviously; at the same time, the isobutylidene-diurea is added to realize the slow release of the fertilizer without affecting the dissolution, and the raw materials are green and environmentally friendly.

The invention relates to a hydrogen sulfate clopidogrel tablet and a preparation method thereof. The method comprises the following steps: firstly, preparing hydrogen clopidogrel and hydroxy propyl cellulose into micro-capsules by utilizing a drying-in-liquid method, then mixing with common auxiliary material in pharmacy, and preparing the tablet by tabletting.

The present invention discloses probiotics containing grape compound powder and a preparation method thereof. The grape powder with natural color and luster, flavor and taste are scientifically matched with functional products of lactobacillus plantarum powder, wheat malt powder, modified dietary fibers, enzyme powder, papaya powder, etc. The preparation method effectively improves the nutrition, food safety and health-care function of the grape compound powder and significantly improves the probiotic property and quality stability of the grape compound powder. Compared with the existing grape compound powder, the probiotics containing grape compound powder is simple in components, natural in color and luster, flavor and taste, high in nutritional value, strong in health-care function, high in contents of bioactive substances, high in number of viable probiotics, strong in probiotic properties, full in types and high in contents of probiotic functional metabolites, high in food safety, and long in shelf life.

The invention discloses a carbon steel surface decarbonizing agent. The carbon steel surface decarbonizing agent comprises the following raw material components of, in percentage by mass, 10% to 40% of sodium hydroxide, 5% to 10% of potassium permanganate, 1% to 5% of sodium dodecyl benzene sulfonate and 50% to 80% of water. The decarbonizing agent can clean 95% or above of a decarburized layer onthe surface, and the decarbonizing efficiency is high; the decarbonizing agent only needs a small amount of dispensing tanks, the concentration of the dispensing tanks in the market is as high as 30%, and the using amount of the decarbonizing agent is greatly reduced; and the decarbonizing agent further has a degreasing function, oil stains on the surface of a steel pipe can be directly removed through the decarbonizing agent, and no extra degreasing agent is needed, so that the production efficiency is improved, and the space is saved.

The invention relates to a novel preparation process for a solid oral preparation which comprises the active components consisting of an oral active renin inhibitor (aliskiren) in an appropriate carrier medium or a medicinal salt thereof and a calcium channel blocker (CCB) amlodipine/levamlodipine or a medicinal salt thereof. Particularly, the invention provides a galenical preparation which comprises a composition of aliskiren hemifumarate and amlodipine or levamlodipine and a novel preparation process. The invention also relates to novel preparation methods for the above-mentioned preparations and application of the preparations as medicines. According to the invention, the method of dry granulation is employed, the problem that the method of wet granulation easily causes increase of relevant substances is overcome, and drug stability is improved; through optimization of the process, the usage amount of excipients is reduced, the purpose of reducing the weight of a tablet is achieved, cost is saved, and the preparations can be easily taken; through particle coating, unwanted reaction of two drugs after mixing is prevented.

The invention discloses an Argentine butternut squash health-care food. The Argentine butternut squash health-care food takes byproducts, namely squash seeds and squash leaves, in a deep processing process of squashes as raw materials; a whole process adopts a low-temperature processing technology, and any essence, spice, food additive and chemical substance are not added; the natural flavor, quality and mouth feel of the squashes are kept to the greatest extent; the food safety and the extraction rate of squash powder component raw materials are effectively improved; a plurality of types of functional raw materials including squash fermented powder, polyglucan, squash malt powder, aloe gel lyophilized powder, squash leaf powder, winter rye peptide, resistant dextrin, beta-glucan and oligosaccharide are scientifically compounded and have synergistic effect so that the nutrition property, functionality, instant solubility, flowability, health-care effect and shelf life of squash powder are remarkably enhanced. Meanwhile, a new way is explored for planting and deep processing of the squashes; the economic income of farmers is increased; environment pollution caused by the fact that the byproducts are wasted is solved, three problems about farmers, rural society and agriculture are effectively solved, and the Argentine butternut squash health-care food has certain economic and social values.

The invention discloses a catfish feed complex enzyme containing a yeast culture and a preparation method thereof. The complex enzyme is characterized in that on the basis of catfish nutrient requirements and water body environment, and the digestion characteristics of catfish, the formula of raw materials is optimized, a wine-brewing yeast culture, a prunus humilis bunge extract, wormwood seed powder, a palatable agent and wheat malt powder are scientifically compounded, wherein the wine-brewing yeast culture has function characteristics of strong nutrient property, biological activity, anti-oxidizing property and the like; the prunus humilis bunge extract can effectively supplement the calcium, iron and soluble fiber, has strong encapsulating function, and can extend the quality warranty period of the feed complex enzyme; the wormwood seed powder can obviously improve the anti-freezing effect and stability of the feed complex enzyme, improve the water-resistant property and luster of the catfish feed, and reduce the powder content in the feed; the palatable agent can greatly improve the palatability and digestion rate of the feed; the wheat malt powder can provide rich nutrient substances, biological active substances and plant enzyme sources. The complex enzyme of the catfish feed containing the yeast culture has the advantages that the digestion rate and yield rate of the catfish are obviously increased, the feed coefficient is reduced, the pollution to a water body is decreased, and the high water quality is maintained.