The invention discloses a comprehensive recovery and processing method for red mud waste residues and titanium dioxide spent liquor. The method comprises the following steps: S1, carrying out mixed leaching on red mud waste residues and titanium dioxide spent liquor, so that leaching liquid and leaching residues are obtained; S2, carrying out leaching liquid treatment on the leaching liquid so as to obtain scandium oxide and a rare earth product, wherein the leaching liquid treatment includes extraction treatment and reverse extraction treatment; S3, carrying out leaching residue treatment on the leaching residues so as to obtain titanium dioxide, aluminum-rich residues and iron ore concentrates, wherein the leaching residue treatment includes acidification, hydrolysis and precipitation treatments. The method solves the problems of industrial waste residue stockpiling, spent liquor discharge, and environmental protection; two kinds of waste materials are comprehensively treated after being mixed, so that the consumption of raw materials is reduced, the production cost is greatly saved, and high-concentration valuable elements such as rare earth, scandium, titanium, iron, and aluminum and the like are obtained, thereby facilitating the implementation of the next recovery process. The method is simple in process and low in equipment requirement, and has certain economic benefits and social significances in the comprehensive recovery of valuable elements such as rare earth, scandium, titanium, iron and aluminum in industrial waste materials and spent liquor.