135results about How to "Increased fluorescence lifetime" patented technology

A luminous body of prolonged fluorescence lifetime characterized by comprising not only an activator but also at least one coactivator selected from the group consisting of La, Ce, Pr, Nd, Sm, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Bi, Sn, Sb and analogues thereof as a further luminescent center for enhancing the thermostability of luminous body. This luminous body excels in thermostability and fluorescence lifetime, so that it is useful as a luminous body for LED.

The present invention provides a method for the synthesis of unagglomerated, highly dispersed, stable core/shell nanocomposite particles comprised of preparing a reverse micelle microemulsion that contains nanocomposite particles, treating the microemulsion with a silane coupling agent, breaking the microemulsion to form a suspension of the nanocomposite particles by adding an acid/alcohol solution to the microemulsion that maintains the suspension of nanocomposite particles at a pH of between about 6 and 7, and simultaneously washing and dispersing the suspension of nanocomposite particles, preferably with a size exclusion HPLC system modified to ensure unagglomeration of the nanocomposite particles. The primary particle size of the nanocomposite particles can range in diameter from between about 1 to 100 nm, preferably from between about 10 to 50 nm, more preferably about 10 to 20 nm, and most preferably about 20 nm.

The invention discloses a method for preparing fluorescent microspheres immunochromatographic test paper strip and quantitative detection method. The invention takes the luminous nano-particles of dual-structure silicon dioxide compound organic dye as a marker, uses the immunochromatographic technology for preparing fluorescent microspheres immunochromatographic test paper strip, and then prepares a detection card which consists of a sample pad, a glass fiber membrane, a nitrocellulose membrane and absorbent paper, wherein the nitrocellulose membrane is fixedly provided with a detection line and a quality control line. In the detection process, the best excitation light souce of fluorescent microspheres is used for excitation; after the emitted fluorescence passes through a filter, a CCD scanning technology or fiber-optic technology is used for collecting, accumulating or multiplicating the emitted spectra which is then converted into a numerical signal; then the measured fluorescence intensity of the detection line is multiplied by a correction coefficient, and later the corrected fluorescence intensity is substituted in a standard curve which is preset in a fluorescence analyzer; and finally, the concentration of an object to be measured in the sample can be automatically calculated and obtained by the fluorescence analyzer. The invention has high sensitivity, accurate quantization and easy operation.

The invention discloses a fluorescent microsphere immunochromatographic testing card for testing five indexes of hepatitis b and a method for preparing the same. The testing card comprises a hepatitis b surface antigen test paper strip, a hepatitis b e surface antigen test paper strip, a hepatitis b surface antibody test paper strip, a hepatitis b e surface antibody test paper strip, and a hepatitis b core antibody test paper strip. Each test paper strip is formed by overlapping and bonding filter paper, a sample pad, a glass fiber film spray-coated with fluorescent microspheres, a cellulose nitrate film and water absorption paper on a bottom plate by glue in sequence, wherein the cellulose nitrate film is coated with antigens serving as a testing area and anti-rabbit antibodies serving as a quality control area; and during a test, after emitted fluorescent light passes a filter, the emitted spectrum is collected, accumulated and multiplied by the CCD scanning technology and then converted into a numerical signal, the numerical signal is multiplied by a correction factor, and the strength of the corrected fluorescent light is substituted in a standard curve of a fluorescence analyzer, so that the concentrations of the five indexes of hepatitis b of the sample can be automatically worked out. The test of hepatitis b viruses by the testing card has the characteristics of specificity, sensitivity, simpleness and accuracy.

The invention relates to the field of synthesis of nano-materials and particularly relates to a method for synthesizing a series of Ag:ZnIn2S4 luminescent quantum dots by using a simple and rapid hydrothermal method in one step. Fluorescence is adjustable in the range of 460nm to 830nm, the fluorescent life is relatively long, and the luminescent quantum dots can be applied to water-decomposed hydrogen production under visible light. The method comprises the steps of firstly, mixing and dissolving silver nitrate, indium nitrate, zinc acetate dihydrate and L-cysteine in an aqueous solution, adjusting the pH value of the solution to 8.5 by using NaOH, adding thioacetamide into the solution, carrying out ultrasonic stirring, then, carrying out a hydrothermal reaction for 4 hours at the temperature of 110 DEG C, and carrying out centrifugal drying after the reaction ends, thereby obtaining Ag@ZnIn2S4 nanocrystals of different ratios. Proven by a photocatalytic hydrogen production experiment under the visible light, the prepared composite photocatalyst has good photocatalytic activity.

The invention discloses an immunochromatography detection card for detecting fluorescent microspheres of ketamine and methyl amphetamine and a preparation method thereof. The detection card is a double-card type, wherein one card is used for detecting the ketamine and the other is used for detecting the methyl amphetamine so as to realize the simultaneous detection of the ketamine and the methyl amphetamine. The detection card sequentially comprises a filter paper, a sample pad, a glass fiber film, a pyroxylin film and a drinking paper; antibodies marked by fluorescent microspheres are sprayedon the glass fiber film; and a detection zone and a quality-control zone are respectively fixed on the pyroxylin film. The invention adopts a nucleocapsid double-structure shining nano-particle compounded by silicon dioxide and fluorescent substance as a mark, and also adopts immunochromatography technology to realize the quick immunoassay of the ketamine and the methyl amphetamine. When in detection, an optimal excitation light source of the fluorescent microsphere is adopted to carry out excitation, and then whether the fluorescent substance exists on detection line can be detected by nakedeye after excited fluorescence passes through a spectral filter device. The detection card has the advantages of high sensitivity, quick detection performance, convenient operation and economical andpractical property.

The invention discloses a blue, yellow and orange light calcium titanium mining quantum dot and a molecular sieve composite luminescent material and a preparing method and application thereof, and belongs to the field of luminescent materials. The method comprises the steps of 1, adding a molecular sieve into a cesium halide solution to stir to obtain a molecular sieve of Cs+ exchange; 2, adopting octadecene, oleic acid, oleylamine and lead halide as raw materials, heating and stirring the mixture at N2 atmosphere, and adjusting the molar ratio of different halogens in lead halide to obtain a lead halide solution; 3, mixing the molecular sieve of Cs+ exchange and octadecene, heating and stirring the mixture at N2 atmosphere, and injecting the mixture into the lead halide solution to react to obtain the composite luminescent material. The molecular sieve composite luminescent material is good in luminous efficiency and high in color purity and has narrow emission peaks at 465 nm (blue), 570 nm (yellow) and 590 nm (orange), the emission peaks is adjustable in the range according to halogen elements, meanwhile the fluorescent lifetime is obviously prolonged, and the composite luminescent material is stable in a solid state and can be applied to the fields of white light LED and the like.

The invention discloses a fluorescence microballoon immunochromatography testing card for quantitatively testing HIV and preparation method. The testing card comprises A and B test paper, a sample cushion, a glass fibrous membrane, a nitrocellulose membrane and drinking paper, wherein, the nitrocellulose membrane is thereon fixed with a test line and a quality control line for realizing the simultaneous test of HIV antibody and HIV p24 antigen. The invention takes nucleocapsid dual-structural light-emitting nano-particles compounded by silicon dioxide and fluorescent substance as marks and adopts immunochromatographic technique to realize quantitative immunoassay of HIV. In the testing process, fluorescence microballoon excitation light source is adopted to carry out excitation, after the emitted fluorescence passes through an optical filter device, all emission spectra are collected, aggregated and multiplied by CCD scanning technique or optical fiber technique, and are then converted into numerical signals, the concentration of the substance to be measured is automatically calculated by using the built-in analysis software in a fluorescence analyzer. The invention has the advantages of high sensitivity, precise quota, fast detection, convenient operation, and economy and practicality.

The invention discloses a fluorescent microsphere immunochromatography detection card for detecting enrofloxacin and a preparation method thereof. The detection card sequentially comprises filter paper, a sample pad, a glass fiber film, a nitrocellulose film and absorbent paper, wherein a fluorescent microsphere-labeled antibody is sprayed on the glass fiber film; a detection area and a quality control area are fixed on the nitrocellulose film; a conjugate of enrofloxacin and carrier protein is sprayed in the detection area; and an anti-mouse antibody is sprayed in the quality control area. By taking core-shell bistructure luminous nano particles complexed by silica and fluorescent substances as labels and adopting immunochromatography in a competition blocking mode, the invention realizes rapid immunoassay of the enrofloxacin. In the detection process, an optimized excitation light source of the fluorescent microsphere is adopted for excitation, the emitted fluorescence passes through a light filter device, and that whether a detection line is provided with fluorescent substances is observed by naked eyes. The invention has the characteristics that: the detection card has high sensitivity and is rapid in detection, convenient to operate, and economic and practical.

The invention discloses nano phase change and energy storage luminescent fibers. The nano phase change and energy storage luminescent fibers comprise the following components: 50%-100% of a polyurethane solid-solid phase change material and 0%-50% of polymethyl methacrylate; the mass content of the components is 100%; and a benzoic acid ternary rare earth luminescent material accounts for 10%-30% of the total mass based on the total amount of the components. The invention further discloses a preparation method of the nano phase change and energy storage luminescent fibers. The polyurethane solid-solid phase change material is used as a fiber forming polymer and the benzoic acid ternary rare earth luminescent material is used as the luminescent material; ethyl acetate and N,N-dimethylformamide are used as compound solvents; and the phase change and energy storage luminescent fibers with the diameters being 30nm-100nm are prepared by an electrostatic spinning technology. The phase change luminescent fibers have the characteristics of high phase transformation enthalpy value in heat storage and releasing, high phase transformation speed, stable luminescent performance, long fluorescence service life and the like; and the phase change luminescent fibers can be widely applied to the fields of medicine and health, electronic information clothing and the like.

The invention discloses a fluorescent microsphere immunochromatographic test strip detecting melamine residue and a preparation method and an application thereof. The test strip comprises a bottom plate, and a sample bonding pad, a nitrocellulose membrane and a water absorbing pad which are successively overlapped and bonded on the bottom plate, wherein a fluorescent microsphere labeled anti-melamine monoclonal antibody is buried on the sample bonding pad, a detection region and a quality control region are fixed on the nitrocellulose membrane, a melamine hapten-carrier protein conjugate is sprayed to the detection region, and a goat anti-mouse antibody is sprayed to the quality control region. The test strip disclosed by the invention is primarily used for detecting the melamine residue and has the advantages of being high in sensitivity, fast to detect, convenient to operate, economical and practical and the like.

The invention relates to ytterbium-doped fluophosphate laser glass and a preparation method thereof. The glass comprises phosphate, fluoride and little oxide, wherein cation contains the following elements in mole percentage: 21.0-35.0 mol percent of P<5+>, 10.0-28.0 mol percent of Al<3+>, 6.0-15.0 mol percent of Mg<2+>, 9.5-13.0 mol percent of Ca<2+>, 8.0-13.0 mol percent of Se<2+>, 4.5-11.3 mol percent of Ba<2+>, 0-27.0 mol percent of Li<+>, 2.0-5.0 mol percent of Na<+>, 0-1.0 mol percent of Nb<5+> and 1.0-3.0 mol percent of Yb<3+>. The glass is prepared by adopting the traditional fusion method. The fluorescence lifetime of Yb<3+> is from 1.70ms to 2.3ms in a 2mm sample, and the Abbe number is between 73.4 and 81.8. Proved by experiments, the ytterbium-doped laser glass is a practical medium material for outputting ultrahigh power and ultrashort pulse laser.

The invention provides a halogenated lead-caesium perovskite fluorescent material. A halogenated lead-caesium quantum dot is modified by adopting protonized carbon nitride, and is induced for self-assembly, and the appearance is turned to a two-dimensional flake structure from the previous spherical shape, but the crystal form cannot be changed; and the defect of the halogenated lead-caesium quantum dot surface can be passivated by the protonized carbon nitride, and the performance in each aspect of the lead-caesium quantum dot can be improved. The experimental result of the embodiment indicates that, compared with an unmodified halogenated lead-caesium quantum dot, the halogenated lead-caesium perovskite fluorescent material has the advantages of relatively high ultraviolet absorption strength and fluorescent strength and long fluorescent service life; and stability of the material is relatively high, and is almost unchanged when being subjected to ultrasonic dispersion in alcohol for2 hours under the condition of concentration being 0.5mg/mL, but the stability of the unmodified halogenated lead-caesium quantum dot is only kept at 58.65 percent under the same condition.

The invention is an L-type zeolite/high polymer luminescent material and a preparation method thereof. The material is composed of zeolite, rare earth ion (Ln3+), organic ligand and macromolecule; its proportion is: 0.0025-0.25mmol rare earth ion/100mg zeolite/8mg organic ligand, and the mass ratio is zeolite-rare earth organic complex:high Molecule=1~5:100. In the present invention, the method of copolymerizing the zeolite loaded with the rare earth organic complex and the polymer effectively suppresses the influence of water molecules and other organic molecules on the luminescence of the rare earth organic complex in the zeolite channel, and at the same time inhibits the leakage of the organic molecule from the zeolite channel, and The material is optically transparent and exhibits the characteristic fluorescence of rare earth ions under ultraviolet light, and can be used in infrared plastic light-emitting diodes, optical data storage devices such as dye nanostructure materials, and improving the physical and chemical properties of polymers.

The invention relates to a neodymium ion doped fluoride laser crystal, and the fluoride laser crystal of MeF2 is doped with monovalent cation M+ which is doped together with the neodymium ion Nd3+. According to the invention, monovalent cation M+ is doped together in Nd:MeF2 crystal; with the proviso that the broadband emmission spectrum characteristic is ensured, the fluorescence quenching effect of Nd ions is reduced, and the fluorescence life is increased.

The invention relates to a method for coating surface of black phosphor nano particles with mesoporous silica, which belongs to the fields of biomedicine and a nano material. preparing the black phosphor nano particles; placing the prepared black phosphor nano particles in a shaking table, oscillating the shaking table while adding a proper amount of TEOS (ethyl orthosilicate), repeating the above step after half hour; after a reaction is completed, performing centrifugation cleaning, discharging a supernatant, and re-dispersing the black phosphor nano particles coated with silica in ultra pure water, the black phosphor nano particles coated with silica can effectively alleviate the easy agglomeration characteristic of black phosphor, and the silica for coating the black phosphor nano particles is used for acoustic imaging, drug loading, and biological imaging.