The invention discloses a three-channel pressure control system and control method at the bottom of a deep-sea double-layer tube well, including double-layer tubes, casings, drill bits, conversion joints, outer sleeves, axial flow pumps, turbine motors, liquid level monitoring sensors, and valve groups Control unit, double-layer pipe return manifold, drilling fluid pumping manifold, drilling pump, drilling fluid circulation tank; the conversion joint is connected to the lower end of the double-layer pipe, and the outer sleeve is sleeved on the upper On the half part, the axial flow pump and the outer sleeve are respectively connected to the lower end and middle part of the conversion joint, the axial flow pump, the turbine motor, and the drill bit are connected in sequence, the double-layer pipe is placed in the casing, and the inner The pipe, outer pipe and casing are concentric strings. The double-layer pipe of the present invention forms three drilling fluid channels, and by changing the lifting performance of the axial flow pump, the self-adaptive control of the bottom hole pressure is realized, and the dynamic balance of the bottom drilling fluid column pressure is effectively maintained.