The invention discloses an 
optical fiber sensor and device based on 
plasma resonance. The 
optical fiber of the sensor is internally provided with a plurality of 
layers of air holes, and the air holes include a central air hole, a first air hole layer, a second air hole layer and a fan annular air hole which are formed from inside to outside, wherein each of the first air hole layer and the second air hole layer contains a plurality of independent air holes; the central air hole is formed in the center of the 
optical fiber, the first air hole layer, the second air hole layer and the fan annular air hole are arranged symmetrically with the central air hole as a symmetrical center, each of the first air hole layer and the second air hole layer has a hexagonal shape, and the side of the fan annular air hole, adjacent to the center, is coated with a film; and the central air hole and the second air hole layer are filled with air mediums, the first air hole layer is filled with a 
metal medium, and the fan annular air hole is filled with a 
liquid medium to be detected. The optical 
fiber sensor has the advantages of simple manufacture, high sensitivity and better comprehensive performance, the detection range of the sensor can be effectively enlarged, and wider application demands can be met.