61 results about "Phenoxethol" patented technology

The invention discloses a collagen composition for skin substrate repair and skin care application thereof, and the collagen composition comprises the following components: 1-3% of soluble III-type collagen, 1-5% of hyaluronic acid, 1-2% of plant extract, 0.1-0.5% of allantoin, 0.2-0.5% of dipotassium glycyrrhizinate, 1-5% of glycerol, 1-5% of butanediol, 1-5% of 1, 2-propylene glycol, 1-5% of 1, 3-propylene glycol, 1-5% of propylene glycol and the balance of water. The cleaning agent is prepared from the following components in percentage by weight: 1 to 2 percent of 1, 2-hexanediol, 0.1 to 0.5 percent of phenoxyethanol, 0.1 to 0.5 percent of ethylhexylglycerin, 0.1 to 0.5 percent of carbomer, 0.1 to 0.5 percent of triethanolamine and the balance of water. The collagen III is added, so that the problems of wrinkles and skin aging are remarkably relieved. According to the skin-care lotion, the oily composition and the water-based composition are reasonably proportioned, so that excellent moistening and moisturizing effects are provided, the moisture balance of the skin is favorably maintained, and the skin is kept soft and moist. The added plant extract, hydrolyzed protein and mineral substances not only nourish and repair the skin, but also can improve various skin problems, enhance the endurance capacity of the skin and avoid the condition that the skin wrinkles are increased during the period of stopping using.

The invention relates to the field of skin care products, in particular to soothing and anti-allergy essence containing a leukocyte extract and a preparation method of the soothing and anti-allergy essence. According to the formula proportion, the composition comprises the following components in percentage by weight: 1 to 75 percent of water, 0.3 to 0.5 percent of p-hydroxyacetophenone, 0.2 to 0.5 percent of an amino acid humectant, 0.1 to 0.5 percent of phenoxyethanol, 0.16 to 10 percent of a leukocyte extract, 0.1 to 1 percent of recombinant III type collagen, 0.5 to 10 percent of a mixed component I, 5 to 10 percent of a mixed component II, 0.1 to 2 percent of tetrahydromethylpyrimidine carboxylic acid and 0.2 to 1 percent of ergosulfide. The facial mask can relieve skin for a long time, promote collagen generation of the skin, and make the skin bright, fine, smooth and moisturized. All people can experience the new charm of gene skin care, and the young state of the skin is kept.

The invention relates to the field of colored cosmetics, and particularly discloses a tearable waterproof eyeliner and a preparation method thereof. The waterproof eyeliner capable of being torn and pulled comprises a container and eyeliner liquid contained in the container, and the eyeliner liquid is prepared from, by weight, 5-10 parts of 1, 3-butanediol; 0.5 to 1 part of phenoxyethanol; 0.5 to 1 part of caprylyl glycol; 30 to 40 parts of water; 2-3 parts of glycerol; 30 to 35 parts of color paste; 2 parts of acrylic resin; 10 to 15 parts of polyurethane resin; and 10 to 15 parts of styrene / isoprene / acrylic resin. The eyeliner prepared by the invention can quickly form a film on the skin of a human body, has a certain thickness, can completely tear off the eyeliner only by rubbing one corner of the eyeliner and then tearing the eyeliner, and also has excellent waterproof and oil-resistant effects.

The invention relates to the technical field of toy materials, in particular to antibacterial and mildewproof plasticine and a preparation method thereof, and the antibacterial and mildewproof plasticine specifically comprises the following components in parts by weight: 40-50 parts of starch, 20-25 parts of glycerol, 3-5 parts of polyethylene glycol, 0.5-0.8 part of an emulsifier, 5-8 parts of sodium chloride, 5-8 parts of hydrogen peroxide, 0.1-0.3 part of potassium sorbate, 0.2-0.3 part of phenoxyethanol, 3-7 parts of a composite nanoparticle material and 15-20 parts of water. The plasticine mostly adopts food-grade raw materials, is non-toxic and harmless, can guarantee the safety of a user, can reduce the allergy risk of children, can effectively inhibit bacterium breeding and avoid mildewing and deterioration of the plasticine by adding potassium sorbate, is suitable for long-term storage or multi-user use scenes, and has a good market prospect. In addition, a special composite nano-particle material is adopted as a carrier to load phenoxyethanol, so that the antibacterial aging can be effectively prolonged, and the long-term antibacterial effect is realized.

The invention relates to the technical field of medicines, and particularly discloses a phenoxyethanol amine compound and application of the phenoxyethanol amine compound as a CaV2.2 inhibitor. The phenoxyethanol amine compound has a structure as shown in a formula (I), and the compound or a tautomer, a stereoisomer, a hydrate, a solvate, a pharmaceutically acceptable salt or a prodrug thereof, and a pharmaceutical composition containing the compound can be used as an N-type calcium channel (CaV2.2) inhibitor, and can also effectively relieve and / or eliminate pain. The phenoxyethanol amine compound provided by the invention has a good application prospect in the field of analgesic drugs.

The present application relates to the technical field of nasal spray, in particular to a kind of nasal use of shangxiangyuan leaf composite spray and its preparation process.The preparation process includes the following steps: the system mass ratio is 1.5-2% of nano microspheres, 2.5-3% of glycerol, 0.3-0.5% of hydroxyethyl cellulose, 0.2-0.3% of phenoxyethanol and 20-25% of citrate buffer are mixed and the rest is made up with pure water, stirred until uniform, encapsulated to obtain nasal use of shangxiangyuan leaf composite spray.The present application carries out esterification reaction of glycerophosphocholine and lauric acid to synthesize glycerophosphocholine-lauric acid ester, glycerophosphocholine-lauric acid ester is the skeleton structure with glycerol, and ester bond is formed, so that glycerophosphocholine retains the structure of glycerophosphocholine while introducing the long chain of lauric acid, has better bioavailability and lower mucous membrane irritation, and provides stable structure and encapsulation efficiency for subsequent formation of liposome coating structure and loading shangxiangyuan leaf extract.

The invention belongs to the technical field of cosmetics, and particularly relates to a 377 whitening and antioxidant composition and application thereof in cosmetics. In the composition provided by the invention, the components such as 377, 577, arbutin, nicotinamide and the like have a whitening effect, and the components such as vitamin E, coenzyme Q10 and the like have an anti-oxidation effect; the lactic acid bacteria fermentation product and the morchella esculenta extract have whitening and anti-oxidation effects, and after the lactic acid bacteria fermentation product and the morchella esculenta extract are combined, the anti-oxidation effect can be multiplied. Other auxiliary materials such as glycerol and butanediol are used for moisturizing, hydrolyzed collagen is used for repairing, and ethylhexylglycerol and phenoxyethanol are used as preservatives, so that the stability of the product is ensured. The components act together, so that formation of melanin can be inhibited in multiple paths, and good whitening and anti-oxidation effects are achieved.

A cleansing composition enhances deposition of actives onto the skin, such as mineral particles and acne treatment actives. The composition includes at least one amphoteric surfactant, at least one glycolipid, at least one cationic polymer from about 0.05% to about 2% by weight of the composition, and at least one cosmetically acceptable solvent. The cleansing system is essentially free of phenoxyethanol and the pH of the composition is between 4 and 8, and the weight ratio of amphoteric surfactant to glycolipid is from about 0.4 to about 4, and the total concentration of amphoteric surfactant and glycolipid combined is about 10% to about 20% of the total weight of the composition.

The invention relates to the technical field of medicines, in particular to an intelligent response type cervical auxiliary fertility gel which comprises the following components in percentage by mass: 0.1-2% of a gel matrix which is selected from one or more of hydroxypropyl methyl cellulose, hydroxyethyl cellulose, sodium alginate and gellan gum; 0.05%-0.5% of a gel adjusting auxiliary agent which is selected from zinc chloride or calcium lactate; the osmotic pressure regulator is selected from one or more of glycerol, glucose, sodium chloride, mannitol, sorbitol, polyethylene glycol and propylene glycol; 0.1%-2% of an acid-base regulator which is selected from one or more of disodium hydrogen phosphate, sodium dihydrogen phosphate, dipotassium phosphate and potassium dihydrogen phosphate; according to the present invention, the toxicity grade of the gel on cervical cells is less than or equal to grade 2 (ISO 10993-5 standard), the cell survival rate is more than or equal to 70%, and the safety is high.

The invention discloses skin mucosa maintenance liquid capable of killing fungi and HPV (human papillomavirus) as well as a preparation method and application of the skin mucosa maintenance liquid, and belongs to the technical field of sterilization and virus removal. The skin mucosa maintenance liquid is prepared from octanol ether, benzalkonium bromide, phenoxyethanol, yermate, parachlorometaxylenol, taetinic acid, chitosan, keratinase, fluconazole, glycerol, borneol, menthol, absolute ethyl alcohol and tween-40. Wherein the skin mucosa maintenance liquid has an effect of regulating apoptosis induction on abnormal cells and an effect on vaginal flora, and has an obvious inhibition effect on cervicitis and colpitis mycotica, namely an anti-inflammatory effect; meanwhile, apoptosis of cells containing HPV16 and HPV18 genes can be induced, shedding of abnormal cells is promoted, diseased cells are killed, and vaginal tissues with pathological changes are removed.

The invention belongs to the technical field of eye patches, and particularly relates to a hydrogel moisturizing eye protection patch and a preparation method thereof. The anti-aging mask is prepared from the following components in parts by weight: 10 to 20 parts of sodium carboxymethyl cellulose, 5 to 10 parts of hyaluronic acid, 4 to 6 parts of polyethylene glycol diacrylate, 1 to 2 parts of aspartic acid, 3 to 6 parts of hydroxypropylated hyaluronic acid, 0.5 to 1 part of antioxidant, 0.5 to 1 part of vitamin E, 3 to 6.5 parts of active extract, 2 to 4 parts of jojoba oil, 8 to 12 parts of glycerol, 5 to 8 parts of propylene glycol, 0.5 to 1 part of phenoxyethanol and 85 to 100 parts of deionized water. According to the hydrogel moisturizing eye protection patch, the hydroscopicity is enhanced through hydroxypropylation of hyaluronic acid, a stable three-dimensional network structure is constructed with sodium carboxymethyl cellulose, active ingredients are uniformly dispersed, and layering is prevented. Glycerin is added to synergistically moisturize, and PEGDA is used as a cross-linking agent to improve the mechanical strength and softness and optimize the distribution of active components.

The invention provides an HPLC (High Performance Liquid Chromatography) detection method of adapalene gel and application thereof, and particularly relates to the technical field of analysis and detection of medicinal components. The HPLC detection method of the adapalene gel is used for simultaneously detecting the contents of adapalene, methylparaben and phenoxyethanol in the adapalene gel; according to the HPLC detection method, a mixed solution of a mobile phase A and a mobile phase B is used as a mobile phase, and a sample solution to be detected is subjected to gradient elution; the initial volume ratio of the mobile phase A to the mobile phase B is (78-82): (22-18); in the gradient elution, the volume ratio of the mobile phase A to the mobile phase B is from (78-82): (22-18) to (28-32): (72-68) and finally returns to (78-82): (22-18). The detection method is simple and can be used for simultaneously determining the contents of adapalene, methylparaben and phenoxyethanol.

Disclosed herein is an advanced anesthetic gel formulation designed for painless, non-invasive dental procedures. The gel incorporates lidocaine hydrochloride and prilocaine hydrochloride as the primary anesthetics, supported by carbomer 940 for viscosity control. Sodium chloride is added to improve electrical conductivity, while triethanolamine maintains an optimal pH balance. Glycerin functions as a humectant to reduce tissue irritation, and allantoin offers anti-inflammatory properties. Phenoxyethanol is included to prevent microbial growth, ensuring the gel's safety and stability. The preparation method involves dissolving these components in purified water, creating a gel that enables effective, non-invasive dental anesthesia through iontophoresis, significantly enhancing patient comfort and procedural efficiency.

The invention discloses toy mud. The toy mud is prepared from the following components in parts by mass: 2 to 6 parts of hydroxyl guar gum, 0.5 to 2 parts of guar gum, 0.2 to 0.8 part of sodium lauryl sulfate, 0.2 to 0.8 part of phenoxyethanol, 0.2 to 0.6 part of potassium sorbate, 0.04 to 0.12 part of sodium dehydroacetate, 1 to 3 parts of silicon dioxide, 0.1 to 0.5 part of titanium dioxide, 7 to 10 parts of glycerol and 80 to 90 parts of ionized water. Compared with an existing toy mud product, the toy mud has the advantages that the hydroxyl guar gum and the guar gum are compounded for thickening, and borax crosslinking is not needed, so that the safety of the toy mud is improved; phenoxyethanol, potassium sorbate and sodium dehydroacetate are adopted for synergic preservation, and compared with a single preservative system, the shelf life of the product can be effectively prolonged; meanwhile, by doping silicon dioxide and sodium lauryl sulfate, the viscosity can be effectively reduced, and the elasticity is improved, so that the use and playing experience is improved; in addition, the working range of the toy mud can be effectively expanded by compounding the modified guar gum with the glycerol, so that the toy mud can be normally used in various temperature environments.

The present invention discloses a whitening and moisturizing cream and a preparation method thereof. The cream comprises: Phase A: allantoin 0.5 - 2.0%, glycerol 2 - 6%, 1,4 - butanediol 2.5 - 7%, sodium alginate 0.5 - 2%, vitamin C 0.2 - 1%, carbomer 0.1 - 0.3%, and an appropriate amount of water; Phase B: squalene 1 - 7%, limnanthes alba seed oil 1 - 15%, polyglyceryl - 3 diisostearate 1 - 6.5%, cetearyl glucoside 1 - 4.5%, sodium stearoyl lactylate 0.5 - 3.5%; Phase C: lophatherum gracile leaf / stem extract 0.01 - 1%, impatiens balsamina flower / leaf / stem extract 0.01 - 1%, luffa leaf extract 0.01 - 0.5%, silk extract 0.1 - 1.5%; Phase D: a whitening composition 0.5 - 1.5%; Phase E: phenoxyethanol 0.01 - 0.3%. The cream prepared by the present invention has excellent moisturizing and whitening effects, and the product is mild, safe and has good stability.

The invention relates to a body scrub cream and a preparation method thereof. The body scrub cream is prepared from the following raw materials in percentage by weight: 3%-8% of sodium methyl cocoyl taurate, 2%-8% of sodium lauroyl sarcosinate, 3%-7% of glycerol, 0.02%-0.07% of sodium citrate, 2%-5% of sunflower seed oil, 0.08%-0.35% of xanthan gum, 0.08%-0.35% of gellan gum, 0.03%-0.07% of disodium ethylene diamine tetraacetate, 0.8%-3% of apple fruit extract, 0.03%-0.08% of citric acid and the balance of water. The bath lotion is prepared from the following components in percentage by weight: 1.8%-3% of black walnut shell extract, 0.2%-0.6% of phenoxyethanol, 0.07%-0.13% of essence, 3%-9% of hydrated silica, 0.4%-0.9% of kiwi fruit extract and 0.4%-0.9% of calendula extract. According to the scheme provided by the invention, cutin can be mildly removed, the skin is kept moist and balanced, and the dull yellow skin is improved.

The invention discloses water-soluble eyeliner liquid powder and a preparation process thereof, and relates to the technical field of cosmetics, the water-soluble eyeliner liquid powder comprises the following raw material components by weight: 4-6% of magnesium stearate; 50% to 55% of synthetic fluorophlogopite CI 77891 tin oxide; 28%-33% of water; 1.5%-2% of glycerol; 5%-8% of a VP / VA copolymer, water and lauryl trimethyl ammonium chloride mixture; 0.2%-0.4% of xanthan gum; 0.2%-0.5% of sodium magnesium lithium silicate; 0.1% of chlorphenesin; 0.5%-0.8% of phenoxyethanol; 0.2% of ethylhexylglycerin; the eye shadow adopts a water-based formula, is free of grease and emulsifiers, is powdery and blocky before use, is smeared with water by hands during use, and is more moist and lighter than common eye shadow; a water-based layer film system has excellent adhesive force, and a layer of soft transparent film can be formed on the eye surface for long-acting makeup; and the personalized requirements of consumers are met.

The invention relates to the technical field of skin repairing and nursing, in particular to skin repairing gel based on an aloe extracting solution and a preparation method of the skin repairing gel. The aloe repair mask is prepared from the following components in parts by weight: 2 to 8 parts of repair agent, 33 to 45 parts of aloe extracting solution, 0.5 to 2 parts of hydroxypropyl methyl cellulose, 6 to 9 parts of glycerinum, 4 to 8 parts of sodium hyaluronate, 0.1 to 0.3 part of phenoxyethanol, 0.2 to 0.4 part of triethanolamine and 0.1 to 0.5 part of butylated hydroxyanisole, wherein the repairing agent is prepared by mixing curdione and modified polyethylene glycol-polycaprolactone according to the mass ratio of 1: (5-10); the modified polyethylene glycol-polycaprolactone is obtained by modifying polyethylene glycol-polycaprolactone and 4-aminocinnamic acid in a mass ratio of 1: (0.05-0.07) under the condition that N-(3-dimethylaminopropyl)-N '-ethylcarbodiimide hydrochloride, N-hydroxysuccinimide and 4-dimethylaminopyridine are mixed. By adopting the repairing agent disclosed by the invention, not only is the antibacterial property of the gel improved, but also the adhesion of the gel on skin tissues is enhanced.

The invention discloses gel containing chrysanthellum indicum, purslane and sodium hyaluronate and capable of delaying senescence and promoting absorption and a preparation method of the gel. The gel comprises water, propylene glycol, butanediol, glycerin, hexanediol, p-hydroxyacetophenone, carbomer, triethanolamine and trace components. The trace components comprise a chrysanthellum indicum extract, a field mint leaf extract, a purslane extract, a pelargonium graveolens extract, a radix sophorae flavescentis extract, an aloe barbadensis extract, sodium hyaluronate, tremella polysaccharide, panthenol, phenoxyethanol, 1, 3-propylene glycol, dipropylene glycol, agar, CI 77491, calcium alginate, polydimethylsiloxane, hydrogenated castor oil, xanthan gum, ethylhexylglycerin, 1, 3-propylene glycol, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate, sodium hyaluronate and sodium hyaluronate. And 1, 2-hexanediol is obtained.

This invention discloses an antiviral disinfectant wipe based on the synergistic effect of biocatalytic sterilization and physical membrane disruption, belonging to the field of disinfectant wipe technology. The disinfectant wipe contains the following raw materials in parts by weight: 85-95 parts spunlace nonwoven fabric, 0.08-0.15 parts modified antimicrobial peptides, 1.5-3 parts modified chitosan, 820-930 parts deionized water, 22-28 parts propylene glycol, 18-22 parts glycerin, 6-9 parts sodium cocoyl glycinate, 0.8-1.2 parts citric acid, 0.8-1.0 parts phenoxyethanol, and 4-7 parts aloe vera extract. This antiviral disinfectant wipe focuses on the synergistic effect of physical membrane disruption and catalytic sterilization. The raw material ratio is scientific, containing highly effective components such as modified antimicrobial peptides and modified chitosan, resulting in excellent sterilization and antiviral effects. The preparation process is standardized, with strict pretreatment of the nonwoven fabric, uniform solution dispersion, and controllable product liquid content. The addition of aloe vera extract makes it mild and non-irritating, allowing for flexible storage and high practicality.

A method of treating and / or preventing a disease in plants, including a step of administering a composition comprising phenoxyethanol to a plant is disclosed. In addition, a method of treating and / or preventing a nematodal infestation in plants, comprising a step of administering a composition comprising phenoxyethanol to a plant is disclosed. Compositions comprising phenoxyethanol used in such methods are also disclosed.

The invention relates to the technical field of cosmetics, and particularly discloses a comprehensive anti-aging cosmetic containing recombined collagen III and recombined collagen IV and a preparation method of the comprehensive anti-aging cosmetic. The raw materials comprise the following raw materials in parts by weight: 5 to 8 parts of recombinant III-type collagen, 3 to 5 parts of recombinant IV-type collagen, 2 to 4 parts of sodium hyaluronate, 4 to 5 parts of nicotinamide, 1 to 2 parts of vitamin E acetate, 8 to 10 parts of squalane, 6 to 8 parts of phytosterol oleate, 8 to 12 parts of glycerol, 5 to 6 parts of butanediol, 1 to 2 parts of carbomer, 0.5 to 1.5 parts of triethanolamine, 0.8 to 1.2 parts of phenoxyethanol and 0.2 to 0.4 part of essence. According to the present invention, by matching the recombinant III-type collagen and the recombinant IV-type collagen, and through the synergistic effect of the recombinant III-type collagen and the recombinant IV-type collagen, the aging is comprehensively resisted from the skin structure level, and the multiple aging signs such as wrinkles, looseness and the like of the skin due to the age increase are effectively improved.

The invention relates to functional toothpaste containing isomaltooligosacharide, which belongs to the field of toothpaste and comprises the following substances in parts by weight: 3 to 6 parts of isomaltooligosacharide, 1 to 2 parts of compound enzyme preparation, 0.6 to 0.7 part of moutan bark extract, 0.4 to 0.6 part of bletilla striata extract, 0.6 to 0.8 part of folium callicarpae pedunculalae extract, 0.3 to 0.5 part of paniculate swallowwort root extract, 8 to 10 parts of nanoscale silicon dioxide, 5 to 9 parts of nanoscale aluminum hydroxide, 10 to 12 parts of glycerol and 28 to 32 parts of sorbitol. The cleaning agent is prepared from the following raw materials in parts by weight: 2 to 3 parts of sodium lauroyl sarcosinate, 1 to 2 parts of cocamidopropyl betaine, 1 to 2 parts of sodium hydroxyethyl cellulose, 0.5 to 0.8 part of xanthan gum, 0.5 to 0.7 part of phenoxyethanol and 20 to 30 parts of deionized water. The synergistic effect of various substances realizes the unification of multiple effects of regulating flora, cleaning and decontaminating, resisting inflammation and inhibiting bacteria, stopping bleeding and easing pain, repairing and protecting, improving mouth feel and the like, and the oral health is comprehensively maintained.

The invention discloses a method for refining and purifying pharmaceutical-grade phenoxyethanol, and relates to the pharmaceutical field. The method for refining and purifying pharmaceutical-grade phenoxyethanol comprises: adding a solvent and a boiling-assisting solid powder to a crude product of industrial-grade phenoxyethanol, heating to reflux, stirring and refining, and then distilling to obtain a crude refined liquid and a solvent distillate; the crude refined liquid is further reduced in pressure and stirred for refining, and then cooled, coarsely filtered, and sterilized and filtered to obtain pharmaceutical-grade phenoxyethanol. The method for refining and purifying pharmaceutical-grade phenoxyethanol provided in the present application can purify impurities such as phenol, ethylene oxide, dioxane, ethylene glycol, etc. in the crude product of phenoxyethanol to almost no detection, effectively improve the purity of the product, meet the requirements for pharmaceutical use, and solve the problem that the related substances of commercially available industrial-grade phenoxyethanol such as phenol do not meet the requirements for pharmaceutical use.

The invention relates to the technical field of care solutions, and discloses a care solution for treating skin hemangioma and a preparation method thereof, the care solution comprises the following components by mass: 10-26 parts of an active component, 1-5 parts of sodium hyaluronate, 5-15 parts of glycerin, 3-10 parts of propylene glycol, 0.5-3 parts of azone, 0.1-1 part of menthol, 0.5-2 parts of phenoxyethanol and 0.1-0.5 part of ethylhexylglycerin. The care solution capable of inhibiting blood vessel growth and promoting cell apoptosis is obtained by specially limiting active components, and substances with anti-inflammatory and repairing effects are also added, so that the efficacy of the care solution is improved.

The invention relates to the field of cosmetic materials, and particularly discloses a liquid powder eye shadow and a preparation method thereof. The liquid powder eye shadow is prepared from the following raw materials in parts by weight: 10 to 30 parts of mica, 0.2 to 1.3 parts of silica, 20 to 60 parts of pearling agent, 3 to 7 parts of octyldodecanol stearoyloxy stearate, 3 to 7 parts of bis-diglycerol polyacyl adipate-2, 3 to 7 parts of polydimethylsiloxane, 1 to 5 parts of pentaerythritol tetraisostearate and 0.5 to 1.5 parts of preservative. The preservative comprises phenoxyethanol and caprylyl glycol, and the pearling agent comprises mica, synthetic fluorophlogopite and iron oxide red; according to the prepared liquid powder eye shadow, the emulsion system is used as a medium to form the liquid powder eye shadow, smooth skin feeling and moistening degree are provided, uniform dispersion of components is promoted, and the prepared eye shadow has a long makeup maintaining effect and color rendering degree.

The invention discloses a novel Burkholderia cepacia resistant to preservatives and application of the novel Burkholderia cepacia resistant to the preservatives. The new burkholderia cepacia Bcc621 is preserved in the Guangdong Microbial Culture Collection Center (GDMCC), the address is the 5th floor, No. 59 building, No. 100 courtyard, Xianlie Middle Road, Guangzhou, the postal code is 510070, the preservation date is December 17, 2025, and the preservation number is GDMCC No: 67496. The bacterium is resistant to kathon, phenoxyethanol, sodium benzoate, potassium sorbate and 1, 3-dihydroxymethyl-5, 5-dimethyl hydantoin, and the bacterium is resistant to drugs of kathon, phenoxyethanol, sodium benzoate, potassium sorbate and 1, 3-dihydroxymethyl-5, 5-dimethyl hydantoin. According to the present invention, the KirbyBauer (KB) drug sensitive experiment results show that the new Burkholderia cepacia is resistant to the preservative;

The present invention provides a preservative for an external preparation for skin and a use thereof. The preservative comprises: hinokitiol; and one or more solvents selected from the group consisting of alkantriol having 3 to 6 carbon atoms, dipropylene glycol, glycerol caprylate, ethylhexylglycerin, and phenoxyethanol. According to one aspect of the present invention, the preservative for an external preparation for skin can be stably held in a liquid state at room temperature and under cold storage conditions, and can exhibit an excellent antibacterial effect after being formed into a dosage form.

The present application relates to the technical field of skin bacteriostasis, and particularly relates to a skin care bacteriostasis composition, application of the skin care bacteriostasis composition, and a skin care bacteriostasis liquid prepared from the skin care bacteriostasis composition and a preparation method of the skin care bacteriostasis liquid. The skin care bacteriostasis composition comprises the following components in parts by weight: 0.1-1 parts of grain extract, 0.1-0.5 parts of forsythia suspensa extract, 0.1-0.5 parts of honeysuckle extract, 0.05-0.5 parts of phenoxyethanol, and 0.01-0.05 parts of benzalkonium chloride. The skin care bacteriostasis composition has no irritation to the skin, can gently clean the skin, kill bacteria and inhibit bacteria, and has the skin care effects of moisturizing and nourishing, and can be used to prepare a cleaning and bacteriostasis product for hand or body skin.

The skincare composition contains Shatavari extract according to this invention. The composition comprises a particular amount of Shatavari extract that is effective in stimulating estrogen receptor, inhibiting 5α-reductase, inhibiting tyrosinase, and is non-cytotoxic. The said composition contains only essential ingredients that do not interfere with the absorption of active ingredients and cause no irritation. In one embodiment, the skincare gel comprises edetate disodium, high molecular weight hyaluronic acid, medium molecular weight hyaluronic acid, low molecular weight hyaluronic acid, niacinamide, Shatavari extract, 2-phenoxyethanol, carbomer, lactic acid, and water.