239 results about "Phosphatidylserines" patented technology

The invention discloses child development formula milk powder. DHA, phosphatidylserine and choline are combined to facilitate child brain development, lutein is added for protecting child eyesight, the components are reasonably combined with substances such as raw milk, various vitamins, mineral substances and dietary fiber (fructo-oligose and galactooligosaccharide) to give play to the synergistic effect, the effect of promoting comprehensive development of the brain, eyesight and the whole body of children of 3-7 years old is achieved, and the milk powder is good in taste and comprehensive in nutrient. The invention further provides a preparation method of the child development formula milk powder. The child development formula milk powder is obtained through the steps of raw milk inspection and acceptance, milk purification, pre-pasteurization, dosing, preheating, homogenizing, sterilization, condensation, spray drying, cooling and the like in sequence, the steps are simple, the process is easy to control, the nutritional ingredient losses are small, the method is applicable to preparing child formula milk powder, and the obtained milk powder is applicable to children of 3-7 years old.

The invention relates to a method for preparing phosphatidylserine and phosphatidylcholine, and belongs to the field of food health-care products. The method comprises the following steps of: extracting soybean meal phospholipid which is used as a raw material by an organic solvent, and then distilling and drying to respectively obtain a phosphatidylcholine crude product and a phosphatidylserine crude product; and separating and purifying the phosphatidylcholine crude product and the phosphatidylserine crude product through a silica gel column of 200-300 meshes, eluting with a mixed organic solvent, concentrating the eluant, and drying to obtain phosphatidylserine and phosphatidylcholine. According to the method, the purities of the phosphatidylserine and the phosphatidylcholine meet requirements of new resource foods, so that the phosphatidylserine and the phosphatidylcholine can be used as new resource dietary supplements and have high economic added values; and the phosphatidylserine and the phosphatidylcholine are prepared at the same time by effectively combining simple extraction of the phosphatidylserine and the simple extraction of the phosphatidylcholine. By the method, the production time is shortened, the production cost is reduced, the production rate is improved, the operation is simple, and the products have safety.

The bionic composite 3D bone tissue engineering rack material has pores of 200-500 microns and porosity over 80 %, and contains bioactive nanometer CaO-P2O5-SiO2 glass powder 50-80 wt%, type-I collagen 10-35 wt%, hyaluronic acid 2-8 wt% and phosphatidylserine 2-8 wt%. Its preparation process includes mixing the above said components homogeneously, adding buffering agent and cross-linking agent for cross-linking treatment, freezing, freeze drying to dewater completely, soaking in Na2HPO4 solution, washing, dewatering and vacuum drying. The material is used as bone substituting material for repairing damaged bone tissue in medical field.

The present invention relates to a preparation suitable for the prevention and/or treatment of vascular disorders, comprising the following fractions:

• • fraction a) consisting of long chain polyunsaturated fatty acids;
  • fraction b) consisting of phospholipids, which fraction contains at least two different phospholipids selected from the group consisting of phosphatidylserine, phosphatidylinositol, phosphatidylcholine and phosphatidylethanolamine.
  • fraction c) consisting of compounds which are a factor in methionine metabolism, which fraction contains at least one member selected from the group consisting of folic acid, vitamin B12, vitamin B6, magnesium and zinc.

The invention discloses a health care food used for improving memory and a preparation method therefor. The health care food comprises a first component and a second component. The first component is one or more selected from phosphatidylserine PS, ginkgo leaves, cistanche, docosahexaenoic acid powder and acer truncatum seed oil powder. The second component is auxiliary materials. The components are weighed and sieved with an eighty-mesh sieve and are mixed uniformly, the mixture is subjected to tabletting or loading, and a health care food is obtained. Through the above mode, a new resource food and traditional Chinese medicines are combined, the effects of improving memory in synergism are achieved, and the health care food is a safe and effective health care food with a reasonable formula, with a good taste and improving memory.

The invention aims at providing a health product for preventing and treating senile dementia. The health product comprises the following components in parts by weight: 3-7 parts of fructus alpiniae oxyphyllae powder, 8-12 parts of lumbricus protein, 6-14 parts of ginkgo biloba extract, 8-12 parts of lucid ganoderma extract, 3-7 parts of cortex cinnamomi extract, 3-7 parts of phosphatidylserine, 12-18 parts of gamma-aminobutyric acid, 3-7 parts of L-tryptophan, 1-3 parts of niacin, 3-7 parts of vitamin C, 2-6 parts of vitamin E, 0.3-0.7 part of vitamin B6, 0.1-0.4 part of vitamin B12 and 0.005-0.015 part of folic acid. The dosage form of the finally formed drug can be powder, tablet or capsule. The health product for preventing and treating senile dementia is prepared from pure plants or extracts, so that no toxic and side effects are caused; and the health product for preventing and treating senile dementia is simple in prescription, low in cost and good in effect.

The invention discloses a method for preparing phosphatidylserine. According to the method, phospholipid and L-serine are subjected to phospholipid translating acylation reaction under the action of phospholipase D to generate the phosphatidylserine, wherein the phospholipid translating acylation reaction is carried out in a homogeneous medium system and the yield of the phosphatidylserine reaches 80-98 percent. The method disclosed by the invention has the advantages that due to the adoption of a green reaction medium, a reaction system is a homogeneous medium system. No phosphatidic acid as a byproduct is generated, high catalytic efficiency of enzyme and favorable quality of products are obtained and the process is safe and environment-friendly.

The invention relates to a composition with an auxiliary memory improvement function. The composition is prepared from the following components in parts by weight: 40-60 parts of DHA spirulina oil, 30-50 parts of phosphatidylserine, 10-20 parts of safflower oil and 5-8 parts of astaxanthin oil. The composition has the technical advantage that the compatibility theory of the compound reflects the latest research results of active components and brain nutrients of the modern research; various unsaturated fatty acids of the brain nutrients and antioxidant ingredients of bioactive factors are reasonably combined; the defects of unilateral memory improvement products are overcome; overall regulation is strengthened from the basis conservation of brain cells; and a healthy brain is rebuilt.

The invention relates to a composition having effects of relieving anxiety and improving sleep. The composition comprises the following components in parts by weight: 100-200 parts of gamma-aminobutyric acid, 50-100 parts of phosphotidyl serene, 100-200 parts of a lily bulb extract, 100-200 parts of a spina date seed extract and 0.01-0.1 part of vitamin B. Experiment proves that when volunteers taking the composition provided by the invention, the sleep quality is obviously improved (situations of being impatient with anxiety, insomnia, dreaminess, and sleep disorders are obviously alleviated), and the effective rate can achieve 80% or above.

The invention provides an emulsion composition containing lecithin, DHA, other fat-soluble substances and purified water. The content of the purified water in the emulsion composition is more than 70% by weight, the weight ratio of the lecithin to the DHA is 1: (0.005-1), the particle size of fat balls in the emulsion is less than 5 mu m, and the other fat-soluble substances comprise one or more of the following components: arachidonic acid, linolenic acid, alpha-linolenic acid, gamma-linolenic acid, linoleic acid, conjugated linoleic acid, conjugated linoleic acid glyceride, phosphatidylserine, polyene phosphatidyl choline, phosphatidyl ethanolamine, phosphatidyl inositol, phosphatidyl glycerol, phytosterol, plant sterol ester, plant stanol ester and medium and long-chain fatty acid. The invention further provides a preparation method of the emulsion composition and application of the emulsion composition in the functional aspects of supplementing phospholipids and unsaturated fatty acids by oral administration, protecting heart and brain blood vessels, reducing blood lipids, reducing blood pressure, treating fatty liver and the like.

The invention discloses DHA phosphatidylserine tablets. The DHA phosphatidylserine tablets comprise sorbitol, microcrystalline cellulose, phosphatidylserine, DHA algae oil powder, taurine, spina dateseed powder, grape powder, acerola cherry fruit powder, lily root flour and magnesium stearate. According to the tablets disclosed by the invention, the value of DHA algae oil can be exerted to the largest extent, and the effects of beneficial components in other raw materials can be fully exerted. According to the tablets disclosed by the invention, the phosphatidylserine and DHA algae oil complement each other, so that the tablets can achieve the effect of retarding intelligence weariness and asthenopia and are particularly suitable for modern brainworkers. In addition, the taurine can improve nerve conduction functions and vision functions, and has important effects on maintaining the normal structure and the functions of the eye tissue.

The invention discloses child formula milk powder capable of prompting calcium absorption and growth, and belongs to the technical field of dairy products. The formula milk powder contains skimmed milk powder, desalted whey powder, vegetable oil, 1, 3-dioleoyl-2-palmitic acid triglyceride, high fructose corn syrup, lactose, compound vitamins, compound minerals, choline chloride, taurine, fructo-oligosaccharide, docosahexaenoic acid powder, bovine colostrum powder, milk mineral salt, spina date seed powder, hydrolyzed yolk powder, phosphatidylserine, lactoferrin powder, bifidobacterium animalisBb-12 freeze-dried powder and xanthophyll. The formula milk powder for children has the effects of promoting calcium absorption of children, promoting growth of children and benefiting brain and vision development. The formula milk powder is simple in preparation process and suitable for large-scale production.

A phospholipid derivative useful for the preparation of liposomes for efficient uptake of an antitumor agent or a gene intracellularly by a target tumor cell, which comprises a residue of an alcohol compound and a residue of a phospholipid, and comprising a peptide between the residue of an alcohol compound and the residue of a phospholipid, and wherein (a) the alcohol compound is an alcohol compound selected from poly(alkylene glycols) and the like, (b) the phospholipid is a phospholipid selected from phosphatidylethanolamines, phosphatidylcholines, phosphatidylserines and the like, and (c) the peptide is a peptide comprising a substrate peptide that can serve as a substrate of a matrix metalloproteinase, provided that one amino acid residue or an oligopeptide containing 2 to 8 amino acid residues may bind to one or both ends of the substrate peptide.

The invention relates to a high-performance liquid chromatography of phosphatidylserine. The High-performance liquid chromatography comprises the steps of (1) preparing a phosphatidylserine standard solution, and using a chloroform-methanol solution to dissolve and fix the constant volume to be 80 to 400ug/ml; (2) preparing a phosphatidylserine sample solution, using the chloroform-methanol solution to dissolve and fix the volume, and diluting and preparing the sample solution of which the phosphatidylserine content is within the concentration range of standard serial solutions; (3) measuring the standard solution and the sample solution under the condition that the high-performance liquid chromatography cooperates with an evaporative light-scattering detector, performing logarithmetics on the peak area of the standard solution as a y-coordinate, performing logarithmetics on the concentration of the standard solution as an x-coordinate, drawing a double logarithmic standard curve, and finding the concentration of the sample solution from the double logarithmic standard curve according to the peak area. The high-performance liquid chromatography has the following beneficial effects: due to the fact that the high-performance liquid chromatography cooperates with the evaporative light-scattering detector, a simple and effective method is provided for the quality control during a phosphatidylserine production process through the entering of different mobile phase volume ratios.

The invention relates to actinomycete for production of phospholipase D and application thereof and belongs to the field of biotechnology. The phospholipase D produced by the actinomycetes after fermentation has catalytic action on soybean phosphatidylcholine and L-serine to efficiently produce phosphatidylserine through transesterification. The actinomycete is collected from a wellhead NO.1066 in Dongfeng town, Dawa County, Panjin city, Liaoning province, and is identified as Streptomycesbottropensis, preserved in the key laboratory for screening of new drugs in Liaoning province under the number of SYP-A-6632, and is preserved in CGMCC under the number of CGMCC No.6993. A screening method of the Streptomycesbottropensis includes: 1, activating strains to be activated; 2, preparing a screening plate; 3, screening and decomposing lecithin strains by a plate method; 4, detecting transesterification activity. The Streptomycesbottropensis has the advantages that the operation process is simple, implementation conditions are mild, phosphatidylserine can be bio-converted efficiently and quickly, and basis of industrial production of phosphatidylserine in future is laid.

The invention discloses a compound soft capsule containing an acanthopanax extract for strengthening the brain and a preparation method of the compound soft capsule. The method comprises the following steps: orderly dissolving the acanthopanax extract, mixed phospholipid and vegetable oil into an ethanol solution of poloxamer, removing ethanol to obtain content of the soft capsule; and encapsulating the content into a soft capsule shell, wherein the dosage of the mixed phospholipid is 90-240 parts by weight, the dosage of the vegetable oil is 140-300 parts by weight and the dosage of the poloxamer is 10-50 parts by weight relative to 100 parts of acanthopanax extract, the mixed phospholipid is prepared from an animal brain extract and adding ingredients, the weight ratio of the animal brain extract to the added ingredients is 1:(2-6) and the added ingredients comprise phosphatidylserine and/or dilinoleoyl phosphatidylcholine. The compound soft capsule for strengthening the brain, which is disclosed by the invention, can be effectively used for assisting improvement of memory, improvement of sleeping, and prevention of senile dementia, and has a good health-care effect.

The invention discloses phosphatidylserine pressed candy and a production process thereof. The phosphatidylserine pressed candy is prepared from raw materials in parts by weight as follows: 285-315 parts of phosphatidylserine, 185-215 parts of soybean lecithin, 3-7 parts of hydroxypropyl methylcellulose, 460-480 parts of isomaltitol, 8-12 parts of silicon dioxide and 9-21 parts of magnesium stearate through pre-treatment, weighing, mixing, granulation, drying, pressing and packaging processes. The phosphatidylserine pressed candy has the advantages that the efficacy of improving nerve cells, improving memory and the like can be realized through scientific matching and the synergetic function of multiple raw materials, and the candy is safe, has no side effects, is convenient to eat and has better market application prospect.