The present invention relates to the technical field of transmit-receive frequency conversion channels, especially to a 16-channel digital multi-beam transmit-receive front-end module. The module comprises a receiving antenna, a transmission antenna, a 16-path receiving channel, a 1-path transmission channel, a 3-path test clock module, a 1-path local oscillator module, a heat dissipation module and a power control module. A transmission channel of the 16-path receiving channel is in signal connection with a receiving antenna, the transmission channel is in signal connection with a transmission antenna, the 16-path receiving channel is connected with the heat dissipation module, the local oscillator module is in signal connection with the transmission channel, the power control module supplies power to the transmission channel, the local oscillator module and the 3-path test clock module, the 3-path test clock module and the 1-path local oscillator module are frequency sources, and each structure is in multi-layer three-dimensional hard connection. The high-density integration, the small size, the light weight and the good stability of the Ku waveband multi-channel digital multi-beam transmit-receive front-end module can be achieved to meet multi-aspect requirements of multi-wave transmit-receive test.