The invention discloses a special high-permeability moisture-curing seal primer for concrete as well as a preparation method and application of the special high-permeability moisture-curing seal primer. The special high-permeation type moist curing seal primer for the concrete comprises a component A and a component B, the component A comprises quaternary ammonium salt modified epoxy resin, graphene, basalt scales, silver-loaded zirconium phosphate, a wetting dispersant, a grafting coupling agent, an anti-settling agent, a reactive diluent, a pigment filler, butanol and xylene; the component B comprises phenolic aldehyde amine, phenolic aldehyde amide, graphene, basalt scales, a wetting dispersant, an anti-settling agent, a pigment filler, butanol and xylene. The special high-permeation type moist curing seal primer for the concrete, provided by the invention, is green and environment-friendly, has low surface treatment requirements on a matrix, can be moist and cured, and can realize single-time coating thick film, and meanwhile, a prepared coating can be used for surface protection of a concrete matrix in severe environments such as a marine environment and the like.