30results about How to "Simple waste treatment" patented technology

The embodiment of the invention relates to the field of synthesis of sulfhydryl compounds, in particular to a preparation method of 3-mercaptopropionic acid. The preparation method includes the stepsthat sodium acrylate and sodium bisulfide or sodium sulfide are mixed and have a reaction; the sodium sulfide is added (or the sodium sulfide and powdered sulfur are added), and the reaction is continued; crystallization and acidification by adding acid are conducted, and a 3-mercaptopropionic acid solution is obtained. According to the preparation method, the costs of raw materials are low, the yield of the 3-mercaptopropionic is high, the purity of the 3-mercaptopropionic is high, solid waste and a solvent can be separated and recycled, a sodium salt is used as an industrial product after crystallization, the solvent is distilled, recycled and reused, and three wastes are easy to process.

The invention relates to a Macitentan preparation method. According to the preparation method, the process is simple, convenient and easy to control, reaction selectivity is good, product quality is high, and the method is suitable for industrial production.

The invention relates to a synthesis method of (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine. The method comprises the steps of: mixing 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl) vinylamine, a chiral catalyst, an acid and a solvent, and reacting; the chiral catalyst The structural formula is shown in formula (I), R is selected from hydrogen atom, alkyl, aromatic ring, alkoxy, halogen atom, amino, cyano, hydroxyl, trifluoromethyl, nitro, ester or amido. (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine with high chiral purity can be generated in one step, and the product is easy to separate and purify with high yield. In addition, the reaction condition is mild, the process is stable, the reaction operation is simple and safe, the production cost is low, the three wastes are easy to handle, the environment is friendly, the raw materials are easily available, the production cost is low, and the method is suitable for industrial production.

The invention relates to a wet process vanadium extraction technology of clay ore, providing a valuable metal technology for extracting vanadium by wet process from vanadium clay ore, which belongs tothe non-ferrous metal metallurgical technology field. The invention is characterized in that disintegrating clay ore, proceeding thermostatic mixing acid leaching reaction as adding sulfuric acid, fluohydric acid and oxidation agent under certain liquid solid volumetric ratio, separating solid and liquid, removing out iron and aluminum and recycling to utilize after leaching solution being treated by multistep pH value regulation and alkali deposition solubilization reaction, depositing vanadium by ammonium salt after purified vanadium being regulated pH value, filtering, drying and calciningammonium metavanadate which is prepared to obtain vanadium pentoxide powder. The invention directly leaches clay ore mixing with acid, has high acid leaching rate, lower energy consumption, short technical process, easy operation and control, low productive cost, environment-friendly and safety, realizes zero discharge in the production process, has no waste gas generation, and recycles waste water and valuable metal, and the recycle rate of vanadium reaches 70-75%, purity of vanadium pentoxide of the product is larger than 99%.

A method of removing chlorosulfonic acid in pentachlorobenzoyl chloride production is disclosed. The method includes (1) feeding chlorine and reacting to produce pentachlorobenzoyl chloride by adopting benzoyl chloride as a raw material and chlorosulfonic acid as a solvent, (2) subjecting the chlorination solution generated in the step (1) to vacuum recovering, (3) cooling the recovered solution to 60-100 DEG C by jacket water cooling, sampling and detecting the content of residual high-oxidizability acids, (4) allowing the mole ratio of sulfuric acid in the recovered solution to sodium chloride to be 1:(2.10-2.5) and reacting the sulfuric acid and the sodium chloride to generate HCl and sodium sulfide, (5) allowing the mole ratio of the chlorosulfonic acid in the recovered solution to sodium bicarbonate to be 1:(0.9-1.0), and (6) allowing the mixture to stand, depositing, centralizing, and subjecting solid to filtration and washing with a solvent to further recover a product. The method has characteristics of cost saving, good product quality, a simple process, easy operation, low environment pollution, and the like.

The invention provides a method for recycling the positive and negative mixed materials of waste ternary lithium-ion batteries, comprising the steps of: disassembling the waste lithium-ion batteries after discharge to obtain mixed powder of nickel-cobalt lithium manganese oxide positive electrode and silicon-carbon negative electrode, battery casing, Copper foil, aluminum foil and diaphragm; the mixed powder and carbonate are ball-milled and then roasted to recover the CO generated during the reaction 2 ; Put the calcined mixture into the dilute alkali solution and filter it, then pass it into CO 2 , the silicon and aluminum in the filtrate are separated, the filter residue is dissolved in acid, and the Li in the filter residue is leached + 、Ni 2+ 、Co 2+ , Mn 2+ and Cu 2+ , after filtering to remove graphite, recover negative electrode material carbon by solid phase method; add sulfide to the leaching solution, adjust the pH value to remove impurity copper, and then prepare nickel-cobalt-manganese hydroxide ternary precursor by co-precipitation method; CO 2 Pass into the filtrate, heat up, concentrate and crystallize to prepare lithium carbonate. The invention has a simple process, can realize the recovery of all components of the nickel-cobalt lithium manganese oxide positive electrode and the silicon-carbon negative electrode mixed material, has low cost, high recovery rate, and the resources can be recycled.

The invention provides a ceftezole sodium powder injection and a synthesis method thereof. The powder injection is composed of more stable ceftezole sodium crystals. The method reacts tetrazoleacetic acid, N, N'-dicyclohexylcarbodiimide and 7-aminocephalosporanic acid in a ratio of 1.4~1.7:1~1.3:1 in dimethyl sulfoxide, and then The reaction intermediate is reacted with 1.1-1.3 times of thiadiazole mercaptan to prepare ceftezole, and after recrystallization with acetone, ceftezole sodium is prepared in aqueous sodium bicarbonate solution. The method is simple and easy, and the total yield is as high as 55.5%.

The invention relates to isosorbide mononitrate sodium chloride injection which belongs to the field of medical preparation. The isosorbide mononitrate sodium chloride injection is prepared from 10-40mg of isosorbide mononitrate, 450-1800mg of sodium chloride, an amount of pH regulator which regulates the pH to 4.0-7.0 and water for injection, wherein the volume of the water for injection is fixed to 100ml. The isosorbide mononitrate sodium chloride injection has high stability and simple preparation process.

The invention relates to the field of fungicides and discloses a preparation method of fludioxonil. The preparation method of fludioxonil of the present invention comprises: under the catalysis of the first base, carry out the first contact reaction of 2,2-difluoro-1,3-benzodiox-4-aldehyde and cyanoacetate to obtain The step of first contacting the product after the contact reaction, and the step of performing the second contact reaction with the obtained product after the first contact reaction directly with p-toluenesulfonylmethyl isonitrile. Through the above technical proposal, a preparation method for fludioxonil with high reaction yield and high purity can be provided, which is easy for industrialization, cheap and easy to obtain raw materials, less three wastes, and high in reaction yield.

The present invention relates to a kind of synthetic method of (S)1-phenyl-1,2,3,4-tetrahydroisoquinoline, the reaction route of described synthetic method is as follows; Described synthetic method comprises the following steps: 1) making The raw material 1 is dissolved in a solvent, and a base and a catalyst are added; 2) hydrogen gas is used for gas replacement to form a hydrogen atmosphere, and a pressurized reaction is carried out to obtain (S)1-phenyl-1,2,3,4-tetrahydroisoquinoline 2 ; Wherein, the catalyst is a BIAMH system catalyst, a D-BIMAH system catalyst or a P-BIMAH system catalyst.

The invention provides a preparation method of Tadalafil crystal form I. The preparation method comprises the following steps: dissolving a Tadalafil crude product and SDS (Sodium Dodecyl Sulphate) inacetonitrile water together, and evaporating, decreasing temperature and crystallizing to prepare the Tadalafil crystal form I. According to the preparation method of the Tadalafil crystal form I, the using amount of a solvent is improved from existing 50 to 80 times to 8 to 20 times by introducing the SDS, so that the using amount of an organic solvent is greatly reduced. Moreover, the method provided by the invention is easy to operate, high in yield, short in production period and lower in cost, and is more suitable for industrial production.

The invention provides a method of extracting 1,5-pentanediamine from a 1,5-pentanediamine salt solution system. An alkaline compound is added into the 1,5-pentanediamine salt solution system to form a solution system containing free-state 1,5-pentanediamine, and then the solution system containing the free-state 1,5-pentanediamine is distilled / evaporated in a paddle dryer or a rake dryer. The 1,5-pentanediamine salt at least comprises one or more of 1,5-pentanediamine sulfate, carbonate and phosphate. The alkaline compound at least comprises solid-state calcium hydrate, magnesium hydroxide, calcium oxide and magnesium oxide. The method is high in practicality, simple and convenient to operate and environmentally friendly, and obviously reduces the raw material cost and operation cost of the whole process. The 1,5-pentanediamine recovery rate of the method is high. The method is environmentally friendly and more suitable for industrial production.

The invention relates to a synthesis method of a nitrogen-containing heterocycles ferrocene derivative. The synthesis method comprises the following steps of (I) introducing an aldehyde group into nitrogen-containing heterocycles in the chemical structure of a raw material a to obtain an intermediate b; (II) performing a hydroxylamine reaction on the aldehyde group in the chemical architecture ofan intermediate b to obtain a hydroxylamine group namely an intermediate c; and (III), performing a reduction reaction on the hydroxylamine group in the chemical architecture of the intermediate c, toobtain the nitrogen-containing heterocycles ferrocene derivative 1. The synthesis method is simple in steps, reagents and equipment which have risks for human bodies or environment do not need to beadopted, and mass production and application of the nitrogen-containing heterocycles ferrocene derivative are convenient.

This invention relates to cephalene onium salt compound and its preparation and synthesis of cephapyrazole sulfate therefrom. It is produced from 7beta-alkyl amido-3-[3-alkyl amido-2-(2-alkyl acyl oxethyl)-1-pyrazole onium group]methyl-3-cephalene- 4-carboxylic salt as intermediate by hydrolyzing it and reacting with alpha-(2-amino thiazole-4-radicle)-alpha-(Z)-methoxy imino acetic acid(benzo thiazole-2-radicle)hydrosulfate. The reacting condition is moderate, its raw materials can be obtained easily, and no expensive and strong irritant reagent is needed.

The invention belongs to the technical field of medicine, and in particular relates to a preparation method of a triazine ring. 2‑Methylthiosemicarbazide, diethyl oxalate, dimethylaminopyridine and metal sodium carry out ring closure reaction, after the ring closure reaction is completed, hydrochloric acid is added to carry out crystallization reaction to obtain the crude product of triazine ring sodium salt, triazine ring sodium salt Hydrochloric acid was added to the crude product for refining reaction to obtain a triazine ring. The invention has simple raw materials, high yield, easy handling and low cost.