The invention provides a treatment method of landfill leachate tail water based on an advanced oxidation combination technology. The treatment method comprises the following steps: (1) putting a certain amount of coagulant in the landfill leachate tail water, standing, and realizing separation in a coagulation unit; (2) enabling a supernatant of the coagulation unit to enter a Fenton unit, addingFeSO4 and H2O2, and fully mixing and reacting with the supernatant; (3) enabling effluent of the Fenton unit to enter a microalgae photobioreactor, and carrying out deep treatment. According to the treatment method of the landfill leachate tail water, provided by the invention, a traditional nitrification/denitrification aerated biological filter unit can be replaced, the microalgae photobioreactor is utilized for carrying deep treatment on the effluent treated by the Fenton unit, residual pollutants such as COD (Chemical Oxygen Demand), organic matters, ammonia nitrogen, nitrate nitrogen andphosphorus in water can be removed, and various indexes of the effluent can be comprehensively upgraded; meanwhile, generated microalgae biomass can be used as animal feed or a biological diesel raw material, so that the treatment cost of leachate is reduced.