104 results about "Fat body metabolism" patented technology

A method is provided for regulating carbohydrate and fat metabolism is an individual which method comprises replacing a proportion of the individual's daily carbohydrate intake with resistant starch and a proportion of the individual's saturated fat intake with unsaturated fat. Also provided are compositions comprising resistant starch and unsaturated fats and methods for making and using the same

The present invention provides methods and compounds for regulating fat metabolism and achieving fat homoeostasis in a subject. Methods and compound for regulating body weight, reducing body fat, and inducing weight loss are also provided, as are methods and compounds for treating or preventing obesity and for preventing or treating conditions associated with altered fat metabolism including, e.g., obesity, diabetes, atherosclerosis, etc.

The present invention relates to a non-human vertebrate animal model displaying an alteration in fat metabolism or in the sensitivity towards leptin or insulin, which model bears a mutation in the gene encoding the spinster like 1 protein (Spinl1). The invention also relates to mutant Spinl1 proteins and nucleic acid sequences encoding these proteins. Furthermore, the invention relates to the use of the non-human vertebrate animal model for the identification of diagnostic markers, or as a model for studying the molecular and physiological mechanisms associated with an alteration in fat metabolism or an alteration in the sensitivity towards leptin or insulin, or for the identification and testing of agents useful in the prevention, amelioration, or treatment of the above conditions. Agents, pharmaceutical compositions, and methods for treating the above conditions are likewise described, as are methods for identifying said agents.

The invention discloses a health-care beverage of guava. The health-care beverage is characterized by comprising the following substances and materials in parts by weight: 30-50 parts of guava, 20-40 parts of bitter gourd, 10-30 parts of Chinese yam, 20-40 parts of folium mori and 5-20 parts of American ginseng. The health-care beverage can be made into dosage forms of tablets, capsules, granules, tea bags and the like; the health-care beverage tastes good, has the original flavor, has the pleasant tea fragrance, is applicable for long-term drinking of glycosuria patients, has the functions of conditioning the insulin secretion and promoting the glycometabolism and fat metabolism, and is capable of conditioning the physiological functions of glycosuria patients, recovering the normal functions of the spleen and stomach and achieving the functions of blood sugar reduction, fat reduction, and glycosuria adjuvant therapy; and when being drunk or taken by ordinary people, the health-care beverage also has the functions of promoting the human body conditioning ability and ensuring the health.

The invention discloses a protein solid beverage, which mainly includes protein powder, β-glucan, L-carnitine, β-carotene, vitamin D3, vitamin E, and vitamin B ₁ , Vitamin B ₂ , niacin, pantothenic acid, vitamin B ₆ , folic acid, vitamin B ₁₂ , vitamin C, calcium, magnesium, zinc and chromium. The protein solid beverage of the present invention has a reasonable formula, and solves the problems of obesity, hyperglycemia, hyperlipidemia and hypertension from the aspects of the speed of blood sugar rise, the efficiency of blood sugar burning and utilization, and the efficiency of fat metabolism.

The invention relates to a polypeptide capable of regulating energy metabolism and application of the polypeptide in preparation of medicines for treating diseases related to disorder of energy metabolism (particularly fat metabolism). The polypeptide disclosed by the invention can achieve the effects of reducing fat absorption, lowering fat accumulation in the liver and regulating the fat metabolism; and compared with a general polypeptide product, the polypeptide disclosed by the invention has the advantage of being orally applied. Therefore, the polypeptide can serve as an active ingredient of a health care product used for regulating the fat metabolism.

The invention provides a probiotic composition and a use thereof as well as food and pharmaceuticals. The probiotic composition comprises bifidobacterium breve; lactobacillus rhamnosus; and bifidobacterium lactis. The three bacteria in the probiotic composition disclosed by the invention can synergistically co-generate and promote growth and metabolism, so that the probiotic composition plays a probiotic role in the intestinal tract, reduces inflammation in the body and promotes fat metabolism, thereby achieving the effects of reducing weight and reducing lipid.

The invention discloses a composition for regulating the sub-health status of the crowd suffering from lipodystrophy. The composition mainly has the effects of reducing the expression of the hypothalamic neuropeptide gamma by influencing human leptin, improving the energy metabolism efficiency, increasing the energy consumption and inhibiting fat synthesis. The other components with fat decomposing effects are combined, so that the metabolism of human adipose tissues is promoted, and the intracellular oxidative phosphorylation effect and synthesis of cell endogenous cholesterol are inhibited. The composition can be used for achieving the effects of effectively infiltrating into the human skin, inhibiting the activity of lipase and reducing the synthesis of fat. By combining the traditional Chinese medicine naprapathy, the absorption and intracellular transport of the composition can be further promoted, the metabolism is promoted, the triglyceride in the fat is decomposed, the excretion of steroid and gallic acid is increased, the excretion of cholesterol and other metabolites can be accelerated, a local shaping effect is achieved, and the contents of glycerin and cholesterol in serum are reduced in an assisted mode. The pharmacological action of the cardiovascular system is improved, and the blood circulation is improved.

The invention discloses a pure Chinese medicinal composition for hyperlipidemia obesity and a preparation method thereof. The composition comprises the following components in parts by weight: 100 parts of spirulina, 60 parts of baikal skullcap root, 120 parts of rhizoma alismatis, 60 parts of codonopsis pilosula, 60 parts of subprostrate sophora, 120 parts of grifola, 50 parts of folium sennae, and 50 parts of polygonum cuspidatum. The medicinal composition for hyperlipidemia obesity is a pure Chinese medicinal capsule, which can be used for soothing liver-qi stagnation, invigorating spleen and supplementing qi, removing stasis, reducing fat and losing weight and promoting fat metabolism by regulating body performance, so that the effect of treating hyperlipidemia and simple obesity can be achieved. The Chinese medicinal composition has the advantages of high safety, no toxic or side effect, no dependence, stable and controllable quality, simple preparation process and the like, is convenient for carrying and taking and can be produced by virtue of conventional equipment.

The invention provides a feed. The feed comprises corn, fish meal, soybean meal, corn gluten meal, docosahexaenoic acid microalgae powder, beet, trace element additives, vitamin additives, amino acid additives, sodium butyrate, medical stone and traditional Chinese medicine composition feed additives. The feed has the advantages of low price, no toxicity, no residues, safety, convenience, comprehensive functions and the like, and can increase animal nutrition, improve fat metabolism of organisms, reduce deposition of abdominal fat of broilers, promote animal growth and development and improve muscle quality.

The invention discloses a feed additive capable of improving an intestinal function of grass carps and application of the feed additive. An effective component of the additive is glycylglutamine; and the adding amount in grass carp feed is 0.25-0.75%. With the adoption of the additive disclosed by the invention, the growth and fat metabolism of the grass carps can be effectively facilitated, and the oxidation resistance of the grass carps is improved; a shape structure of small intestines of the grass carps can be improved; villus height, crypt depth, mucous membrane thickness, the quantity of goblet cells and the quantity of lymphocytes of the intestines are increased; and the secretion of an intestinal digestive enzyme can be accelerated, and the feed additive has active improvement effect on the intestinal function of the grass carps.

The invention discloses application of a traditional Chinese medicine composition in preparation of drugs for preventing and treating abnormal fat metabolism diseases. The traditional Chinese medicinecomposition is prepared from herba artemisiae scopariae, radix bupleuri, radix sophorae flavescentis, radix et rhizoma rhei and folium isatidis. Through screening of a large number of experiments, the traditional Chinese medicine composition provided by the invention has a good effect of reducing the content of total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) of a hyperlipidemia animal model, and has a certain effect of increasing high-density lipoprotein cholesterol (HDL-C). The clinical experiments find that the Kuhuang granules can obviously improvebiochemical indexes and imaging evaluation results of fatty liver patients. In addition, the experimental result of the drug-induced liver injury shows that the traditional Chinese medicine composition provided by the invention can significantly improve the drug-induced liver injury and has the effect of preventing the liver injury.

The invention provides applications of a grapefruit extract in preparation of lipid-lowering functional food, healthy food or medicines. The grapefruit extract is prepared by the following steps: performing acetone ultrasonic extraction, rotary evaporation, solid-phase extraction column passing and vacuum drying to freeze-dried powder of extracts of a grapefruit oil gland layer, an albedo layer and a mesocarp layer. The body weight of high-lipid induced fat C57BL/6 mouse can be reduced in vivo through the grapefruit extract, the masses of the liver and adipose tissues can be obviously decreased, the triglyceride, total cholesterol and low-density lipoprotein cholesterol containing in serum can be obviously reduced, and the triglyceride and total cholesterol contained in the liver can be reduced. The grapefruit extract can be used for prevention and treatment of fat metabolism abnormality related diseases as functional food, healthy products or preventive and treatment drugs.

The invention relates to the technical field of healthy food, and particularly discloses a compound anti-aging composition, a compound anti-aging tablet and a preparation method and application of the compound anti-aging composition and the compound anti-aging tablet. The compound anti-aging compositio is prepared from 100 to 200 parts of NMN, 2 to 3 parts of PQQ, 5 to 15 parts of quercetin, 200 to 400 parts of betaine and 300 to 400 parts of auxiliary materials, wherein the auxiliary materials comprise one or more of stevioside, calcium phosphate, magnesium stearate and silicon dioxide. According to the compound anti-aging compositio disclosed by the invention, the betaine is matched with the PQQ and the NMN, so that the cell osmotic pressure can be effectively regulated, the intestinal tract is protected, the stress reaction of the compound anti-aging compositio is reduced, and fat metabolism and protein synthesis of a human body are promoted; the effects of promoting energy metabolism of human cells and accelerating metabolism are also achieved while the immunity of the organism is enhanced; and the betaine can effectively reduce the probability that NMN, PQQ and quercetin are oxidized, so that the anti-oxidation, anti-inflammation and anti-aging effects of quercetin, PQQ and NMN on human cells after the quercetin, PQQ and NMN are compounded are further stimulated.

The invention provides application of a ring finger protein Rnf20 gene. By using a Cre-loxp system, an adipose tissue specific Rnf20 gene knockout mouse model is successfully prepared through mating of an Rnf20Flox/Flox mouse and an Adiponectin-Cre + mouse. Adipose specific Rnf20 gene knockout mice (Rnf20Fox/Fox; Adipectin-Cre +) and the control mice (Rnf20Flox/Flox) were used as experimental subjects to study the function of the Rnf20 gene in fat metabolism through animal models induced by age and high fat diet. The results show that compared with thecontrol mice, the adipose-specific Rnf20 gene knockout mice has lipid metabolism disorders that could mimic the pathogenesis of human lipodystrophy. The model is an ideal model for researching lipodystrophy, and has important application value.

The invention discloses a radix puerariae fiber tea, prepared by mixing radix puerariae fiber and roxburgh rose pulp, wherein the radix puerariae fiber is obtained by washing, peeling, pulverizing andpress-filtering radix puerariae. The radix puerariae fiber tea has good mouthfeel, good color, rich sweetness, low calorie and satiety, can supplement energy and nutrients required by the human body,and can enhance fat metabolism and immunity.