27 results about "Impurity profiling" patented technology

The invention discloses a basic nickel carbonate impurity analysis method and system. The method comprises the following steps: judging whether each first identification result is an abnormal identification result or not; if a certain first recognition result is an abnormal recognition result, obtaining a certain target original image corresponding to the certain first recognition result, determining a certain position of the certain target original image in a certain original image sequence, and selecting other original images from other original image sequences according to the certain position; and inputting other original images into the image recognition model, outputting a second recognition result corresponding to other original images by the image recognition model, and performing basic nickel carbonate impurity analysis on a certain original image sequence and each original image in other original image sequences by adopting a preset impurity analysis strategy, and obtaining an analysis result of basic nickel carbonate on each production line. The efficiency of basic nickel carbonate impurity analysis in the whole production line can be effectively improved.

The invention relates to the field of oxide impurity analysis, in particular to a method and system for analyzing the content of impurities in oxide. The method comprises the following steps: setting oxide impurity samples, constructing a reference impurity database through the oxide impurity samples, and analyzing the reference impurity database to obtain a reference impurity data set; the method comprises the following steps: acquiring a to-be-detected spectrogram sequence of a to-be-detected oxide sample, analyzing the to-be-detected spectrogram sequence to obtain to-be-detected spectrogram subsequences, and constructing a to-be-detected spectrogram event chain; analyzing the spectrogram event chain to be detected to obtain a de-noised spectrogram event chain; analyzing the de-noised spectrogram event chain in combination with a reference impurity data set to obtain a matched impurity data set and an unmatched impurity data set of the to-be-detected oxide sample; and analyzing the matched impurity data set and the unmatched impurity data set to obtain an impurity analysis result of the to-be-detected oxide sample. According to the invention, the impurity identification precision can be improved.

This invention discloses an impurity analysis instrument for chemical testing, belonging to the field of chemical testing technology. It includes a main body, a feeding box fixedly installed on the top of the main body, a mixing chamber inside the main body, a feed pipe fixedly connected between the feeding box and the mixing chamber, a first motor fixedly installed on the main body, a stirring rod fixedly installed on the output end of the first motor, and stirring blades with numerous small holes fixedly installed on the stirring rod. A discharge pipe fixedly installed below the mixing chamber, communicating with the interior of the mixing chamber. Multiple detectors are fixedly installed inside the main body corresponding to the positions of the discharge pipe, with a detection head fixedly installed on the input end of each detector, located inside the discharge pipe. A filter screen is fixedly installed above the interior of the discharge pipe. A collection mechanism is provided on the main body and the mixing chamber. This invention achieves the effect of uniform distribution of impurities within the solution, ensuring the accuracy of the test results, while also automatically collecting metallic products.

This invention discloses a method and system for analyzing impurities in basic nickel carbonate. The method includes: determining whether each first identification result is an abnormal identification result; if a first identification result is an abnormal identification result, acquiring a target original image corresponding to the first identification result, determining a position of the target original image in a sequence of original images, selecting other original images from other sequences based on the position; inputting the other original images into an image recognition model, the image recognition model outputting a second identification result corresponding to the other original images, and using a preset impurity analysis strategy to perform basic nickel carbonate impurity analysis on each original image in the first and other sequences, obtaining the analysis results of basic nickel carbonate on each production line. This method can effectively improve the efficiency of basic nickel carbonate impurity analysis throughout the entire production line.

The application discloses a sample solution preparation method for trace impurity analysis of high-purity trimethylaluminum, and belongs to the technical field of trace impurity analysis, and the preparation steps are as follows: a magnetic stirring rotor is placed in a flue gas absorption bottle, nitric acid solution is added, and a magnetic stirring heater is started; high-purity trimethylaluminum is added into an oxidation decomposition bottle, a gas cylinder pressure reducing valve and an air inlet valve are opened, oxygen-nitrogen mixed gas in a gas cylinder is transported into the oxidation decomposition bottle, then an air outlet valve and an automatic one-way valve are opened, when there is no high-purity trimethylaluminum in the oxidation decomposition bottle, all the valves are closed, and a sample solution for trace impurity analysis of high-purity trimethylaluminum is obtained. The application adopts the method of oxidizing and decomposing trimethylaluminum by using high-purity oxygen-nitrogen mixed gas, and then nitric acid solution is used to dissolve aluminum oxide powder to prepare an aluminum ion nitric acid solution. The application has the advantages of single chemical variety, low concentration, no need for additional treatment of tail gas, simpler device structure, easy operation, low investment cost, safety, economy, and environmental protection.

The present application relates to the technical field of raw coal ash content regulation, in particular to a raw coal ash content feedforward automatic regulation system, comprising a coal sampling module, a sub-mine impurity detection module, a coal impurity analysis module, a washing parameter analysis module, a washing amount tracking module, an execution terminal and a cloud database. The physical and chemical detection of each sub-mine ensures the accuracy and scientificity of raw coal ash content detection, greatly improves the reliability of raw coal ash content detection results, and further provides strong data support for the analysis of subsequent washing operation parameters. By analyzing the washing parameters of raw coal mines, the washing effect of coal mines can be effectively optimized, achieving higher washing amount, improving the utilization value of coal mines, avoiding resource waste caused by unreasonable washing amount operation, and further improving the consistency and stability of washed clean coal.

A pretreatment method for the analysis of trace impurities in magnesium pyrocene involves placing a precisely weighed, dried sampling bottle and sampling device into an inert atmosphere chamber. Magnesium pyrocene is then placed into the sampling bottle using the sampling device, the bottle cap is tightened, and the inert atmosphere chamber is removed. The total weight of the sampling bottle and the magnesium pyrocene contained therein is accurately weighed. A 5% (w / w) dilute acid solution is then added dropwise to a Class 100 cleaning table to allow the reaction to proceed. After the reaction slows down, a small amount of the 5% (w / w) dilute acid solution is added to fully dissolve the sample. The solution is first heated at a low temperature, and the sample on the inner wall of the bottle is rinsed clean with the 5% (w / w) dilute acid solution. The temperature is then increased to allow for a complete reaction, and the acid is removed until nearly dry. The substance in the sampling bottle is then dissolved with the 5% (w / w) dilute acid solution to prepare the corresponding test solution for subsequent detection. This invention solves the problems of complex processes and the easy introduction of other trace impurities in existing technologies.

AI-BASED LABORATORY DEVICE FOR IMPURITY PROFILING OF HERBAL AND SYNTHETIC COMPOUNDS

This utility model relates to the technical field of textile testing equipment, and discloses a raw cotton impurity analyzer with self-cleaning function. The analyzer includes an analyzer with two conveyor wheels on its inner wall, two first fixing frames fixedly connected to its inner wall, multiple permanent magnets installed on the inner wall of an impurity collection funnel, a second fixing frame fixedly connected to the outer wall of the impurity collection funnel, a first spring on the outer wall of a fixing rod, a vibrating oscillator installed on the inner wall of the analyzer, a collection box slidably connected to the inner wall of the analyzer, and a shock-absorbing component at the bottom of the analyzer. In this utility model, multiple permanent magnets are installed at the bottom of the impurity collection funnel, within the inner wall of the second fixing frame, and the first spring is positioned between the two fixing rods, allowing the two fixing rods to slide against the inner wall of the analyzer, thus fixing the impurity collection funnel and facilitating its installation and removal.

The present application relates to the technical field of agricultural machinery, and provides a grain impurity analyzer, which comprises a screening mechanism, the screening mechanism comprises a vibrating device and a screening assembly in transmission connection with the vibrating device, the screening assembly eccentrically vibrates under the drive of the vibrating device, so that the grain to be analyzed in the screening assembly vibrates along a preset direction, and the preset direction is at least two directions; the screening assembly is provided with a feeding port, a first discharging port and a second discharging port; an impurity weighing device, the first discharging port is in communication with the feeding port of the impurity weighing device, so that the impurities screened out by the screening mechanism enter the impurity weighing device for weighing; and a clean grain weighing device, the second discharging port is in communication with the feeding port of the clean grain weighing device, so that the grain screened out by the screening mechanism enters the clean grain weighing device for weighing. The precision of impurity screening is improved, and the weighing accuracy is ensured.

The invention belongs to the technical field of material synthesis, analysis and detection, and provides a clofazimine impurity C, a salt and a preparation method thereof, and a clofazimine detection method. The invention provides a clofazimine impurity C and a salt thereof. The clofazimine impurity C has a structure as shown in a formula I. The applicant predicts the toxicity of the clofazimine impurity C through a Cramerrules model, and the result shows that the grade of the toxic harmful substance of the clofazimine impurity C is class III, and the clofazimine impurity C has significant toxicity or reactive functional groups. Meanwhile, according to the prediction of a Carcinogene model (IRFMN-ISSCAN-CGX) 1.2. 2 model, the impurity C of the clofazimine is a cancerogen, and three cancerogenic alarms exist. The clofazimine impurity C has potential genetic toxicity and carcinogenicity. The clofazimine impurity C and the salt thereof can provide convenience for impurity analysis and research of clofazimine bulk drugs and preparations thereof.

The invention discloses a method for detecting impurities in nitrosamine of vortioxetine hydrobromide by liquid chromatography-mass spectrometry. According to the method, an ultra-high performance liquid chromatograph-mass spectrometer is adopted, and octadecylsilane chemically bonded silica is used as a filler; the chromatographic conditions are as follows: the column temperature is 35-45 DEG C, the temperature of a sample introduction disc is 6-8 DEG C, the flow velocity is 0.3-0.5 ml / min, and the sample introduction amount is 2-20 microliters; and eluting with a gradient mobile phase. Mass spectrum conditions are as follows: a triple quadrupole tandem mass spectrometer is used for detection, an ion source is an electrospray ion source, and a positive ion scanning mode is adopted. Calculating the content of the impurity G by adopting an external standard method. The method for analyzing the impurity G in the vortioxetine hydrobromide, established by the invention, is strong in specificity, high in stability, high in accuracy, high in precision and strong in durability, and can be used as a method for detecting the content of the impurity G in the vortioxetine hydrobromide.

The invention relates to a cleanliness testing method. The method comprises the following steps: an impurity collection step (10): collecting impurity particles on a to-be-detected part on a first carrier made of a water-soluble material; a carrier dissolving step (20) of completely dissolving the first carrier and dispersing the impurity particles in an aqueous solution to form a particle solution when the first carrier together with the impurity particles collected thereon is placed in the aqueous solution; an impurity recollection step (30): collecting impurity particles in the particle solution by using a second carrier; and an impurity analysis step (40): detecting and analyzing the impurity particles on the second carrier. The method is particularly suitable for the application that an aerostatic press is adopted to collect impurity particles on a to-be-detected component onto a first carrier in a filter paper form and a microscope is adopted to detect and analyze impurity particles on a second carrier in a filter paper form. The component to be detected may be a fuel cell.

The invention provides a separation and purification method for degradation impurities in urea [13C] granules, and relates to the technical field of pharmaceutical analysis. The method comprises the following steps: carrying out an acid thermal degradation reaction on a urea [13C] granule sample by using a hydrochloric acid solution to obtain a degradation reaction solution; and carrying out liquid chromatography separation and purification on the degradation reaction liquid, and collecting a fraction rich in steviol-19-O-glucoside. And the fraction rich in steviol-19-O-glucoside can be efficiently and accurately obtained. According to the method, time-consuming and labor-consuming structural speculation and directional synthesis steps in traditional impurity analysis are avoided, the analysis cost is effectively reduced, the analysis period is effectively shortened, and meanwhile, the degradation impurity separation accuracy is improved.

The invention discloses an octafluoropropane crude product automatic sample injection and impurity analysis system and a use method thereof. The system comprises a color detector, two ten-way valves, two six-way switching valves and a thermal conductivity detector, a silica gel drying column is connected to a branch between a first pneumatic valve and a second pneumatic valve, and the other end of the silica gel drying column is connected with a sample inlet pipe; the detection range of the color detector covers the whole silica gel drying column, and the color detector is linked with the pneumatic valve; the first ten-way valve is respectively connected with a second twenty-way valve and a first six-way switching valve; the first six-way switching valve is further connected with a second twenty-way valve and a second six-way switching valve. And the second six-way switching valve is connected with the thermal conductivity detector. According to the invention, HF and F2 are prevented from corroding the chromatography, automatic continuous analysis of the octafluoropropane crude product is realized, detection equipment is effectively protected, and the service life of the equipment is prolonged; the impurities in the octafluoropropane are detected in groups, so that the analysis efficiency of an analysis sample is effectively improved, the analysis time is shortened to 30 minutes, and the ppm-level content impurity detection requirement is met.

The invention provides a pretreatment method for analyzing trace impurities in ferrocene. The method comprises the following steps: feeding a dry sampling bottle and a sampling device which are accurately weighed into an inert atmosphere operation box, taking a metal organic compound by using the sampling device, putting the metal organic compound into the sampling bottle, tightening a bottle cap of the sampling bottle, and taking out the inert atmosphere operation box; accurately weighing the total weight of the sampling bottle and ferrocene in the sampling bottle, dropwise adding a first preset amount of concentrated acid on a hundred-grade clean bench, heating to fully dissolve the concentrated acid, removing the acid until the concentrated acid is nearly dry, cooling, adding a second preset amount of concentrated acid along the bottle wall of the sampling bottle, heating, digesting, and removing the acid until the concentrated acid is nearly dry; and heating and dissolving by using a dilute acid solution with solute mass percentage of 5% to prepare a corresponding solution to be detected for detection. The concentrated acid is dropwise added to decompose the metal organic compound ferrocene to form soluble ferrocene, and the method has the advantages of easiness in operation, good safety, short detection time, no environmental pollution, good analysis result repeatability, wide applicability and the like.

The invention relates to the technical field of impurity protein detection, and particularly discloses a fluorescence low-cost detection-based oxytetracycline impurity protein content detection method, which comprises: S1, sample preparation, S2, fluorescence labeled antibody preparation, S3, standard curve preparation, S4, sample detection, and S5, result analysis. Specific detection of impurity protein in an oxytetracycline sample is achieved through the fluorescence labeled antibody, the result is consistent with the assumed concentration, and the method is high in sensitivity, high in specificity and suitable for accurate analysis and application in drug quality control; by adopting a fluorescence labeling technology and combining simple spectrograph detection, high use cost of a large instrument is avoided, the detection cost is reduced, meanwhile, the method has high sensitivity and accuracy, the reliability of a detection result is ensured, and the method is suitable for detecting the content of the oxytetracycline impurity protein and also suitable for detecting the content of the oxytetracycline impurity protein. And the method can be expanded to impurity analysis of other drugs and quantitative analysis of target proteins in biological samples, and has relatively high universality and practicability.

The invention belongs to the technical field of analysis and testing of impurities in high-purity samples, and particularly relates to an ICP-MS (Inductively Coupled Plasma Mass Spectrometry) detection method for trace impurities in high-purity yellow phosphorus. Through accurate weighing of a yellow phosphorus sample and a mixed acid-microwave digestion technology, the sample is rapidly dissolved under high-temperature and high-pressure conditions, and the sample is diluted and then directly detected on a machine; the yellow phosphorus sample pretreatment and on-machine measurement efficiency is improved. The method mainly comprises the following steps: S1, weighing a yellow phosphorus sample; s2, sample digestion; and S3, ICP-MS machine detection is carried out. According to the method, a yellow phosphorus sample is digested by adopting a mixed acid-microwave digestion method and then is detected by adopting an ICP-MS (Inductively Coupled Plasma Mass Spectrometry), and a proper amount of oxalic acid is added into the digested nitric acid, so that elements such as impurities As, Mg, Na, Ca and Fe in the yellow phosphorus sample can be effectively dissolved and released within a short time; in the detection process, a collision reaction tank mode is adopted to eliminate element interference, 23 trace impurity elements can be detected at the same time, the detection efficiency is high, the detection time of each batch of samples is shortened to be within 4 h, and the detection limit of each element is reduced to 10 ppt or below.

This invention proposes a method and system for improving the insulation resistance of ceramic capacitors, relating to the field of ceramic capacitor technology. The method involves acquiring capacitor usage scenario data, performing scenario determination analysis on the usage scenario data to obtain scenario determination analysis data, conducting ceramic material analysis based on the scenario determination analysis data to obtain ceramic material analysis data, performing ceramic structure dimension analysis and adjustment based on the ceramic material analysis data to obtain various analysis and adjustment data, performing joint dimension and impurity analysis based on the various analysis and adjustment data to obtain joint dimension and impurity analysis and adjustment data, and performing production process impurity analysis and adjustment based on the joint dimension and impurity analysis and adjustment data to obtain insulation resistance improvement data. This invention achieves multi-stage synergy and scenario-driven capability for improving insulation resistance.

The application provides a method for determining the content of impurity elements in concentrated isotopes based on HR-ICP-MS, and belongs to the technical field of element detection. The method provided by the application only needs to consume a small amount of concentrated isotope sample, and is particularly suitable for accurate analysis of the purity of high-value to-be-detected substances such as concentrated isotopes. In the application, the use of element mixed solution series standard substances can realize the simultaneous analysis of 68 kinds of impurity elements, which is significantly superior to the impurity analysis method based on the ICP-MS method in the prior art. The application utilizes an improved matrix effect correction method to realize the correction of the matrix effect through the measurement of the sensitivity factor under the to-be-detected matrix. The application designs a special sample measurement process, measures the process blank without the matrix by the external standard method, and measures the impurity content in the sample by matrix matching, so that the measurement result is more accurate.

The gas chromatography device for impurity analysis in F2 / N2 mixed gas provided by the invention has the characteristics of high corrosion resistance, high sensitivity, high integration level and simplicity and convenience in operation, and a hastelloy injection valve and a pipeline are combined with a plasma emission detector and a helium carrier gas system; f2 corrosion is effectively prevented, the detection sensitivity is remarkably improved to 10 ppb or below by utilizing the advantages of plasma selective emission spectrum, meanwhile, the separation process is optimized through a multi-chromatographic-column path, a reverse blowing valve and a center cutting technology, synchronous detection of multiple impurities such as CF4, O2 and N2 is achieved, total analysis can be completed through one set of equipment, extra dangerous sources or complex maintenance is not needed, and the cost is low. The cost and the operation difficulty are remarkably reduced, and the method is particularly suitable for the accurate analysis requirements of high-end fields such as semiconductor photoetching and superconducting scientific research on trace impurities.

The invention provides a pretreatment method for analyzing trace impurities in diethyl tellurium, which comprises the following steps: taking the diethyl tellurium in an inert atmosphere operation box by adopting a sampling device, putting the diethyl tellurium in a dry sampling bottle, sealing the dry sampling bottle, and taking the dry sampling bottle out of the inert atmosphere operation box; weighing the total weight of the dry sampling bottle and the diethyl tellurium, and dropwise adding a first dilute acid solution into the dry sampling bottle on a hundred-grade super clean bench, so that the first dilute acid solution reacts with the diethyl tellurium to obtain a first solution; adding concentrated acid into the dry sampling bottle, enabling the concentrated acid to react with the first solution, and heating to react to generate toxic gas, so as to obtain a second solution; and dissolving the second solution in the dry sampling bottle by adopting a second dilute acid solution to prepare a solution to be detected. The method has the advantages of simplicity and convenience in operation, good safety, short detection time, no environmental pollution and the like, does not introduce other trace impurities, and also has the advantages of good repeatability and wide application.

The application discloses a medicine impurity analysis and detection method, relates to the technical field of medicine impurity detection, and comprises the following steps: obtaining a plurality of medicine samples with different impurity contents, preparing corresponding medicine solutions for chromogenic reaction, collecting corresponding chromogenic images, obtaining medicine impurity chromogenic image data, and performing image preprocessing to obtain image features of the chromogenic images and obtain chromogenic feature sample data; based on the chromogenic image sample data, an impurity feature relationship model is established by using the image features of the chromogenic images and the corresponding impurity contents; for the medicine to be detected, the impurity feature relationship model is used to analyze and detect the impurity content; the application is used to solve the problem that the existing medicine impurity detection technology cannot quickly and reliably detect the impurity content according to the color features of the Chinese medicinal decoction pieces after chromogenic reaction, so as to meet the large-batch pre-detection requirement.

The invention provides a pretreatment method for analyzing trace impurities in trimethyl indium, which comprises the following steps: taking trimethyl indium in an inert atmosphere operation box by adopting a sampling device, placing the trimethyl indium in a dry sampling bottle, sealing the dry sampling bottle to obtain a metal organic compound, and taking the dry sampling bottle out of the inert atmosphere operation box; weighing the total weight of the dry sampling bottle and the metal organic compound, and adding a water-insoluble organic solvent into the dry sampling bottle on a hundred-grade super clean bench, so that the organic solvent reacts with the metal organic compound to obtain a first solution; adding a first dilute acid solution into the dry sampling bottle, reacting concentrated acid with the first solution, and heating to remove alkane to obtain a second solution; and adding a second dilute acid solution into the second solution in the dry sampling bottle to prepare a solution to be detected. The method has the advantages of being easy to operate, good in safety, short in detection time, free of environmental pollution, good in analysis result repeatability, wide in applicability and the like.

The invention relates to the technical field of pharmaceutical analysis, in particular to a detection method for simultaneously determining main components and related substances of compound glycyrrhizin tablets by utilizing an HPLC (High Performance Liquid Chromatography) method. The HPLC-CAD method is adopted to measure the content of main components and related substances of the compound glycyrrhizin tablets, and high sensitivity and good reproducibility are achieved. Compared with a derivatization method, the detection method disclosed by the invention is simple and rapid to operate, and can realize the determination of the content of the main components and the detection of related impurities without carrying out derivatization reaction on the sample. Meanwhile, by optimizing chromatographic conditions, main components and impurities in the compound glycyrrhizin tablets can be well separated. Further, a plurality of unknown impurities can be identified by mass spectrometric detection. In conclusion, the accuracy and the sensitivity of impurity analysis in the compound glycyrrhizin tablet can be improved, and a targeted production process optimization scheme can be provided for related research.

The utility model discloses chemical impurity analysis and detection equipment, and relates to the technical field of chemical raw material detection, the chemical impurity analysis and detection equipment comprises an experiment table, the top of the experiment table is provided with an adjusting assembly, one side of the top of the experiment table is fixedly connected with a supporting rod, and the top of the supporting rod is fixedly connected with a containing cylinder; the top of the containing cylinder is movably connected with a cover plate. According to the chemical impurity analysis and detection equipment, the adjusting assembly is installed, a servo motor drives a lead screw to rotate, then a sliding block and a sealing baffle are driven to move up and down, accurate control over the flow of a sample in a through opening in the conveying pipe is achieved, and it can be ensured that the sample enters a detection analyzer at the stable flow speed; the problems that impurity signals are diluted or omitted due to too high flow velocity and detection time is too long or signals are overlapped due to too low flow velocity are solved, so that the detection accuracy and reliability are remarkably improved, and the position of the sealing baffle can be flexibly adjusted according to needs to adapt to different samples and different detection requirements.