31 results about "Oxygen sensing" patented technology

The invention discloses a method and a device for detecting the energy metabolism level of cells and organoids. According to the detection method disclosed by the invention, the acidification rate and the oxygen consumption rate of the extracellular microenvironment are obtained through signal response of hydrogen ions and the dissolved oxygen sensing electrode, and meanwhile, a dynamic detection microcavity is constructed by utilizing a metabolism detection device, so that the sensitivity and the accuracy of measurement are improved. By adopting different drug intervention schemes, the energy metabolism pathway of the cells can be regulated and controlled, so that the evaluation of the two energy metabolism pathways of glycolysis and aerobic respiration of the cells is realized. The in-situ and high-sensitivity cell energy metabolism detection method and device are provided by detecting the concentration change of the specific analyte of the extracellular microenvironment, the method has the universality of two-dimensional and three-dimensional cell models, a brand new platform is provided for scientific research and drug effect screening based on an in-vitro model, and the application prospect is wide.

The utility model provides an oxygen sensor and belongs to the technical field of sensors. The problem that an existing oxygen sensor does not have the filtering function is solved. The oxygen sensor comprises an oxygen sensor body, the oxygen sensor body is connected with an external controller through a connecting line, the oxygen sensor body is detachably provided with an air inlet piece, one end of the air inlet piece extends into the oxygen sensor body, and the other end of the air inlet piece extends out of the oxygen sensor body. Air inlet holes are formed in the peripheral side of the air inlet piece, a filter screen is arranged at the bottom of the air inlet piece, a sliding piece is arranged on the oxygen sensor body, a connecting spring is arranged between the sliding piece and the oxygen sensor body, a plurality of balls capable of moving left and right are arranged on the oxygen sensor body, and a first clamping groove is formed in the air inlet piece. A second clamping groove is formed in the sliding piece. The filter has the advantage of good filtering effect.

The application discloses a photosensitizer and tissue oxygen synchronous measurement device, and belongs to the technical field of photoelectric measurement. The application uses a semiconductor diode laser as an excitation source, the emission wavelength of which is determined according to the absorption characteristics of oxygen sensing material and photosensitizer, a laser beam is coupled into a detection optical fiber to form excitation light through optical components, so that the excitation light can excite the oxygen sensing material and the photosensitizer at the same time, the oxygen sensing material with near-infrared emission is used, the phosphorescence emission wavelength of which is far away from the fluorescence of the photosensitizer, the spectral intensity of near-infrared is used to determine the tissue oxygen concentration, the spectral intensity of red light is used to determine the concentration of the photosensitizer, in addition, the fluorescence and phosphorescence of the oxygen probe are both oxygen-dependent, so that the fluorescence intensity of the oxygen probe in the red light region can be accurately removed, thereby avoiding the influence of the fluorescence intensity of the oxygen probe on the detection of the photosensitizer fluorescence, and then realizing that the fluorescence for characterizing the photosensitizer concentration and the phosphorescence for characterizing the oxygen concentration are not overlapped, and realizing the synchronous measurement of the photosensitizer and the tissue oxygen.

The utility model relates to an oxygen sensing ceramic processing conveying line, its characterized in that: including conveying module, connecting module, clamping base and oxygen sensing ceramic clamping module, adopt the connecting module of plug -in type to install the oxygen sensing ceramic clamping module that entire installation is on clamping base on the conveying chain at equal intervals, this kind of connection can conveniently maintain and replace clamping base, the oxygen sensing ceramic clamping base with different size first arc -shaped groove can be embedded in T type through -slot, oxygen sensing ceramic clamping arm can be equipped with the clamping block with different second arc -shaped groove size to satisfy the clamping to different types of oxygen sensing ceramic, and the versatility is better, in addition, adopt oxygen sensing ceramic locking arm to lock the side of oxygen sensing ceramic clamping arm, guarantee the stability of oxygen sensing ceramic in the conveying process.

The invention discloses a neonatal resuscitation auxiliary system based on white noise and bionic stroking. The neonatal resuscitation auxiliary system comprises a resuscitation master control module, a white noise generation module, a bionic stroking module, a physical sign monitoring module and a man-machine interaction module. The white noise generation module comprises an audio processing unit, a loudspeaking unit and a volume adjusting unit, and is used for generating and playing white noise with a specific frequency spectrum and a sound pressure level; the bionic stroking module comprises a driving unit, a stroking execution unit and a pressure sensing unit; the physical sign monitoring module comprises a heart rate sensing unit, a blood oxygen sensing unit and a body temperature sensing unit; the man-machine interaction module comprises a display screen and a keyboard. According to the invention, by combining two kinds of stimuli of white noise and stroking according with neonatal neurophysiological characteristics, a synergistic effect is generated, the stability of respiratory circulation is more effectively promoted, the uncertainty of traditional manual operation stimuli is replaced, and the stimuli parameters can be accurately controlled and repeated, so that clinical research and effect evaluation are facilitated.

A composition and method for measuring the oxygen partial pressure of a tissue. The composition is implanted subcutaneously or into an organ inside a human body, and the oxygen partial pressure of the tissue is measured by fluorescence.

The application discloses a plateau special-purpose extremely simple intelligent monitoring nasal oxygen tube adapting device and relates to the technical field of medical nursing instruments.The application comprises an ear-hanging flexible fixing support, a micro main control box and a blood oxygen sensing and detecting head, the ear-hanging flexible fixing support is detachably sleeved outside a general nasal oxygen tube, the blood oxygen sensing and detecting head is electrically connected with the micro main control box, a main control module, a vibration early warning module and a power supply module are arranged in the micro main control box, a data processing unit and a blood oxygen threshold value determination program are arranged in the main control module, the vibration early warning module is connected with the main control module and realizes silent alarm through mechanical vibration, and the power supply module supplies power to each component.The blood oxygen detection site is far away from an oxygen supply area, airflow interference is eliminated, the special environment of plateau low temperature and poor peripheral circulation is adapted, detection data is accurate and stable, silent early warning is achieved through vibration, no light and loudspeaker noise are generated, night-time disturbance is avoided, and the application is suitable for long-term continuous monitoring in a ward.

The invention discloses a pneumatically-controlled cerebral arterial thrombosis dynamic micro-fluidic blood vessel chip integrated oxygen sensing system. The system sequentially comprises a perfusion channel layer, a deformation layer, a glass oxygen barrier layer and a pore control layer from top to bottom, the perfusion channel layer is connected with an injection pump through an external silicone tube and is used for realizing dynamic culture of cells in the channel; the deformation layer is an elastic film and is deformed along with the increase of external air pressure, so that the channel forms a narrow area, and an oxygen probe is arranged in the elastic film and is used for oxygen monitoring; the air hole control layer is connected with a vacuum pump through an external silicone tube and applies air pressure to the deformation layer. The deformation layer is effectively controlled through an external vacuum pump, so that the stenosis of a channel is accurately controlled, different stenosis of blood vessels under physiological conditions is simulated, and changes of mechanical microenvironments such as fluid shear force, culture solution flow rate and flow and oxygen content chemical microenvironments are recorded; and a convenient and effective new platform is provided for studying the injury mechanism of ischemia reperfusion.

The present invention relates to highly porous, bioresorbable electrospun sensors for optical detection of tissue oxygenation and processes of making and using same. Multiple sensor compositions are described that are focused on different applications / oxygen ranges. Such sensors alleviate the risk of leaving the sensor implanted in a subject, typically have as good or better oxygen sensing capabilities and comparable performance life span as non-degradable sensors and unlike sensors made from general bioresorbable materials maintain a desired porosity as they degrade. Thus, such sensors may remain integrated in a subject's body while they degrade and maintain the ability to sense oxygen for their performance life span.

The invention relates to the technical field of biological interface sensing, in particular to a multi-mode soft stretchable wearable sensing patch and a preparation method and application thereof, the sensing patch comprises a stretchable substrate, a blood oxygen sensing unit, a myoelectricity sensing unit and a muscle sound sensing unit; the stretchable substrate comprises a front surface and a back surface which are opposite; the blood oxygen sensing unit and the myoelectricity sensing unit are sequentially arranged on the front face of the stretchable substrate. The blood oxygen sensing unit and the myoelectricity sensing unit are separated through a first packaging layer, and the myoelectricity sensing unit is packaged through a second packaging layer; the muscle sound sensing unit is located on the back face of the stretchable substrate. The wearable sensing patch provided by the invention can be stably attached to the skin under a dynamic condition; moreover, multi-modal integrated acquisition of myoelectricity, muscle sound and blood oxygen signals can be realized on the sensing patch, and meanwhile, real-time, dynamic and synchronous monitoring of multi-modal signals is realized, so that a reliable basis is provided for comprehensive evaluation of the physiological state of a human body.

Apparatus, systems, and methods are provided that generate in vivo maps of oxygenation measurements of biological tissue. These may include surgical instruments and stand-alone imaging systems with incorporated oxygen sensing capability. Oxygenation maps can be determined via fluorescent or phosphorescent lifetime imaging of an injectable probe with an oxygen-dependent optical response. Probe configuration and methods and apparatus of injecting the probe into the tissue are provided. Methods and apparatus for temperature compensation of temperature-dependent lifetime measurements are provided to improve oxygenation measurement accuracy. Oxygen maps may be registered with visible light images to assist in assessing tissue viability or localize anomalies in the tissue. Resulting oxygen images may be used for various applications including, but not limited to, guiding surgical procedures such as colorectal resection through use of intraoperative sensing, enhanced endoscopic imaging for identifying suspect lesions during colonoscopy, and external imaging of tissue such as assessing peripheral vascular disease.

The application discloses a nitrogen-oxygen sensor, a nitrogen-oxygen sensing control system and a method for measuring nitrogen-oxygen, and the nitrogen-oxygen sensor comprises a sensor element, a gas diffusion path is arranged in the sensor element, a first diffusion barrier and a second diffusion barrier are sequentially arranged on the gas diffusion path, a functional electrode group is arranged on the sensor element, and a heater is integrated on the sensor element and used for heating the sensor element; the functional electrode group comprises an oxygen electrode unit, a reference electrode unit, a nitrogen oxide electrode unit and a common electrode unit, the oxygen electrode unit is used for pumping oxygen and generating a first current signal positively related to the oxygen concentration, the reference electrode unit is used for detecting the oxygen partial pressure, and the nitrogen oxide electrode unit is used for decomposing nitrogen oxide and generating a second current signal positively related to the nitrogen oxide concentration; and the application can simplify the sensor structure, reduce the manufacturing cost, and improve the measurement accuracy of the oxygen and nitrogen oxide concentration, the anti-interference ability and the high-temperature stability.

The invention discloses a super-hydrophobic wood-based optical oxygen sensing material as well as a preparation method and application thereof, and belongs to the technical field of optical sensing composite materials. The invention aims to overcome the problems of strong hygroscopicity, unstable signal, insufficient surface performance and the like of the existing wood-based optical oxygen sensor. According to the invention, balsa wood is taken as a matrix, metalloporphyrin Gd-HMME is loaded in the matrix, and the surface of the matrix is coated with a PDMS / SiO2 coating, so that the material is endowed with a super-hydrophobic characteristic. Under excitation of an ultraviolet laser, the material can realize effective detection of oxygen concentration. The surface energy of the sensing material is low, pollution is not easy to adhere, signal drift caused by humidity and water vapor is avoided, and the reliability of a sensing result is remarkably improved.

The utility model relates to a full premix wall-hanging stove self-adjusting structure, it includes wall-hanging stove body and oxygen sensing analysis structure, the wall-hanging stove body includes wall-hanging stove control module, exhaust pipe and communication interface, oxygen sensing analysis structure includes oxygen sensing analysis module, flue gas detection transmission channel and signal transmission channel, one end of the flue gas detection transmission channel is connected with the oxygen sensing analysis module, the other end of the flue gas detection transmission channel is connected with an oxygen sensing probe, the oxygen sensing probe corresponds to the smoke exhaust pipe and is detachably connected to the smoke exhaust pipe, one end of the signal transmission channel is connected with the oxygen sensing analysis module, and the other end of the signal transmission channel is connected with the oxygen sensing analysis module. And the other end of the signal transmission channel is connected with the communication interface of the wall-hanging stove body.

Road structure layer maintenance detection equipment comprises an overground detection unit, an underground detection unit, a control system and a feeding bin, and the control system and the feeding bin are located on one side of a road; the overground detection unit comprises a camera, and the camera is connected with the control system and used for obtaining road surface image information; the underground detection unit comprises a pavement structure layer located on the upper layer, a pavement structure cushion layer located on the lower layer and a bionic pipeline located in the middle, the bionic pipeline is communicated with the feeding bin, and a photosensitive and oxygen sensing component electrically connected with the control system and a membrane potential control unit duct piece are arranged in the bionic pipeline. The invention also provides a corresponding detection method, the crack is effectively supervised through the camera before and after repair, the crack judgment accuracy is improved, effective processing can be ensured in the initial stage of crack occurrence, and the problem that the repair difficulty is increased due to the fact that the crack cannot be detected and is too long due to a single monitoring source is prevented.

The present application relates to a kind of photonic crystal-based oxygen sensing film and its preparation method, the oxygen sensing film includes: by the photonic crystal substrate formed by the self-assembly of periodically arranged microspheres, the oxygen-sensitive probe layer of phosphorescent metalloporphyrin compound attached to the photonic crystal substrate;The photonic crystal substrate has the photonic band gap matched with the emission peak wavelength of oxygen-sensitive probe.The oxygen sensing film in the present application is synergized by the Purcell effect of the band edge of photonic crystal and the slow light enhancement effect, realizes the high sensitivity, fast response and good selectivity of oxygen detection, and preparation process is environmentally friendly controllable.

The invention discloses a room-temperature phosphorescent material as well as a preparation method and application thereof. The room-temperature phosphorescent material has a structure as shown in the following formula, wherein R is selected from any one of-F,-Cl,-CN,-CF3,-CH3,-H,-OCH3 and-OCF3. The room-temperature phosphorescent material is of a semi-alicyclic structure with a unique EXO configuration, different molecular stacks are formed through hydrogen-bond interaction of amino groups on different benzene rings, the room-temperature phosphorescent material with oxygen sensitivity and oxygen retardation is prepared, and the room-temperature phosphorescent material has great application prospects in the fields of organic photoluminescence and oxygen sensing detection.

The invention discloses an oxygen sensor and a preparation method of an oxygen sensing substrate. The oxygen sensor comprises a substrate, the substrate is provided with a zirconium oxide layer, and the zirconium oxide layer comprises the following components in percentage by weight: 59.9 wt% to 67.5 wt% of Zr, 5.23 wt% to 6.6 wt% of Y, 0.05 wt% to 1.21 wt% of Nb, 0.44 wt% to 3.57 wt% of Ba, 0 to 0.46 wt% of Si and 0.18 wt% to 2.77 wt% of Al; and the phase of the zirconium oxide layer comprises the following components in percentage by weight: 88.5 to 98.5 percent of tetragonal phase zirconium oxide, 0.83 to 6.7 percent of barium aluminate, 0 to 3.55 percent of mullite phase and the balance of monoclinic phase zirconium oxide. The substrate of the oxygen sensor provided by the invention has relatively good mechanical properties.

The application relates to the field of sensing devices, and discloses a base-doped organic electrochemical transistor, a dissolved oxygen sensing patch and application thereof. The base-doped organic electrochemical transistor comprises a substrate, a dissolved oxygen sensitive gate, a source electrode, a drain electrode and a base-doped semiconductor layer between the source electrode and the drain electrode. The dissolved oxygen sensing patch comprises the base-doped organic electrochemical transistor and a flexible water-absorbing substrate. The PSS:PEDOT semiconductor layer in the organic electrochemical transistor is subjected to base-doping modification treatment, so that the sub-threshold region just coincides with the oxygen reduction potential, the advantages of the transconductance effect of the organic electrochemical transistor can be fully exerted, and the sensitivity of the sensor is greatly improved. The dissolved oxygen sensitive gate in the base-doped organic electrochemical transistor has the advantages of high selectivity and high sensitivity to oxygen, good robustness and low cost and can be mass-produced.

The invention belongs to the technical field of gas sensing, and particularly relates to a phosphorus-lanthanum co-doped TiO2-based oxygen sensing material as well as a preparation method and application thereof. According to the oxygen sensing material, TiO2 is used as a main crystalline phase, and meanwhile, phosphorus and lanthanum are introduced to form a P / La co-doped structure; wherein the doping amounts of the P element and the La element are respectively 1-3 mol% of the Ti element, and the particle size of the material is 1-3 [mu] m. Wherein the synergistic doping of P and La not only regulates and controls the lattice structure of TiO2, but also induces the generation of a large number of oxygen vacancies, and significantly increases the specific surface area and the number of gas adsorption active sites. The material can be synthesized from TiO2 powder, soluble lanthanum salt and phosphoric acid / phosphate through a solvothermal method, and is applied to a Pt interdigital electrode to obtain a high-performance oxygen sensing gas sensitive element. The problems that an existing gas sensitive element is insufficient in sensitivity, poor in selectivity and poor in environmental stability in ppb-level low-concentration oxygen detection are solved.

The invention relates to a desktop incubator environment parameter cooperative control method and system based on a split type framework. The method comprises the following steps: a master control module generates a unified synchronous acquisition instruction and sends the unified synchronous acquisition instruction to a temperature and humidity sensing unit, a carbon dioxide sensing unit and an oxygen sensing unit through a flexible circuit board and a built-in bus so as to trigger the temperature and humidity sensing unit, the carbon dioxide sensing unit and the oxygen sensing unit to start data acquisition in the same sampling period and obtain original environment parameter data with time synchronization; original environment parameter data with time synchronism are uploaded to the main control module through a built-in bus and a flexible circuit board; in the main control module, fusion of cross sensitivity compensation calculation is carried out on the original environment parameter data, and a fusion environment parameter data set is generated; and sending the fusion environment parameter data set to an external terminal through the wireless communication module. According to the technical scheme, the synchronism, precision and system adaptability of the monitoring data are effectively improved through synchronous acquisition and data fusion.

The application relates to a repeatable sterilization flat-bottom culture centrifugal bottle, belonging to the technical field of biological experimental equipment, which comprises a bottle body, the bottom of the bottle body is a flat bottom, the upper portion of the bottle body is provided with a bottle mouth, the bottle mouth is screw-connected with a bottle cap, a centrifugal self-locking sealing structure is arranged between the end surface of the bottle mouth and the bottle cap, a sampling valve is arranged on the side wall of the bottle body, and a dissolved oxygen sensing film is arranged on the lower portion of the bottle body. The bottle body is provided with a self-closing sampling valve integrated on the side wall, is matched with the bottle cap provided with the centrifugal self-locking sealing structure and the replaceable air permeable film, can realize 30 sterilization cycles without leakage and multiple sterile sampling, and the air permeable film can be replaced individually without disassembling the cap.

The invention provides a wheat seed vigor detection method based on oxygen sensing, and the wheat seed vigor detection method based on oxygen sensing comprises the steps of pretreatment, detection and statistics, and specifically comprises the following steps: selecting full, consistent, insect-hole-free and mildew-free wheat seeds, and carrying out aging treatment to obtain pre-detected wheat seeds a; the method comprises the following steps: adding a single seed of a to-be-detected wheat seed a into a sample tube, transferring into a seed vitality instrument, monitoring an oxygen consumption curve in real time, and screening out five parameters including an initial metabolic rate SMR, an oxygen metabolic rate OMR, time R50 for 50% of seeds to reach 50% of oxygen concentration, area AUC50 under the 50% oxygen concentration curve and relative germination time RGT; the indexes of SMR, OMR, R50, AUC50 and RGT are used for determining the seed vigor. Compared with the prior art, the method has the advantages that breakthrough progress is realized in detection efficiency, parameter value and variety suitability, and particularly, the technical blank of wheat seed oxygen sensing activity detection is filled through a three-in-one innovative design of'medium-parameter-algorithm '.

The invention discloses a detection device for detecting an oxygen sensing chip, and relates to the technical field of oxygen sensor detection equipment, the detection device comprises a detection box mounted on a detection table, the side wall of the detection box is provided with a plurality of mounting holes for plugging of plugs of the oxygen sensing chip, and the mounting holes are connected with the oxygen sensing chip. The side part of the detection box is provided with an adjusting pipeline in butt joint with a factory mixed gas pipeline, and the side part of the detection box is provided with an oxygen pipeline in butt joint with a factory oxygen supply pipeline; partition plates distributed in the height direction of the detection box are slidably arranged in the detection box. According to the detection device for detecting the oxygen sensing chips, by arranging the partition plate, the turning plate, the telescopic piece and other structures, partition isolation control over the detection box is flexibly achieved, meanwhile, test gas makes full contact with the plug, the test gas can rapidly and evenly cover sensitive areas of the oxygen sensing chips, the response time is shortened, and the detection efficiency is improved. And the consistency and the reliability of simultaneous detection of multiple chips are improved.

The invention belongs to the technical field of semiconductor lasers, and particularly relates to a VCSEL epitaxial structure for oxygen sensing and a manufacturing method thereof.The VCSEL epitaxial structure comprises a GaAs substrate, a GaAs buffer layer, an N-type DBR layer, a multi-stage active layer, a P-type DBR layer and a GaAs Cap layer, the GaAs buffer layer is located on the surface of the GaAs substrate, the N-type DBR layer is located on the GaAs buffer layer, the multi-stage active layer is located on the N-type DBR layer, and the P-type DBR layer is located on the GaAs Cap layer. The P-type DBR layer is located on the multi-stage active layer, and the GaAs Cap layer is located on the P-type DBR layer; the VCSEL epitaxial structure adopts a Bragg reflector (DBR) structure composed of a low refractive index layer and a high refractive index layer, and the DBR structure is in non-periodic distribution and has a disordered thickness sequence, so that a wider reflection spectrum width is realized, and the laser can be stably tuned within the range of 760-765 nm.

The invention provides a rice seed vigor detection method based on oxygen sensing, and the rice seed vigor detection method based on oxygen sensing comprises the steps of pretreatment, detection and statistics, and specifically comprises the following steps: selecting full, consistent, insect-hole-free and mildew-free rice seeds, and carrying out aging treatment to obtain pre-detected rice seeds a; agar is added into distilled water to prepare an agar solution b with the concentration of 0.4-0.6%; adding 700-900L of the agar solution b into a sample tube, adding a single seed of the to-be-detected rice seed a into the sample tube after solidification, transferring into a seed vitality instrument, monitoring an oxygen consumption curve in real time, and screening out two parameters, namely an initial metabolic rate (SMR) and an oxygen metabolic rate (OMR); the SMR and OMR indexes are used for judging the seed vigor.

The application relates to the technical field of biological interface sensing, in particular to a multi-modal soft stretchable wearable sensing patch as well as a preparation method and application thereof. The sensing patch comprises a stretchable substrate and a blood oxygen sensing unit, an electromyography sensing unit and a muscle sound sensing unit. The stretchable substrate comprises opposite front and back surfaces. The blood oxygen sensing unit and the electromyography sensing unit are sequentially arranged on the front surface of the stretchable substrate. The blood oxygen sensing unit and the electromyography sensing unit are separated by a first encapsulation layer, and the electromyography sensing unit is encapsulated by a second encapsulation layer. The muscle sound sensing unit is located on the back surface of the stretchable substrate. The wearable sensing patch provided by the application can be stably attached to the skin under dynamic conditions. Moreover, multi-modal integrated collection of electromyography, muscle sound and blood oxygen signals can be realized on the sensing patch, and real-time, dynamic and synchronous monitoring of multi-modal signals is realized, thereby providing a reliable basis for comprehensive evaluation of human physiological states.

Aspects of the disclosure generally relates to articles, compositions, and systems for oxygen detection in vitro or in vivo. In some embodiments, the disclosure relates to a metal complex, e.g., a compound comprising at least one metal-carbon bond. In some embodiments, the disclosure relates to metal organic frameworks (MOF). The MOFs comprise a plurality of metal clusters and a plurality of ligands that are coordinated with the plurality of metal clusters. In some embodiments, the disclosure relates to liposome-complexes (e.g., liposome-metal complexes and / or liposome-MOF complexes). In some embodiments, the metal complex, MOF, and / or liposome-complexes are configured to undergo photoluminescence following activation. Methods for in vitro and in vivo oxygen sensing and / or detecting intratumoral oxygen tensions using said articles, compositions, and system are also disclosed herein.