The invention provides a leaching range monitoring method in an in-situ leaching uranium mining process. The monitoring method includes the steps that 1, a numerical model is established through computer numerical simulation software, wherein the steps of conducting model generalization, conducting model numeralization, establishing the numerical model, correcting the numerical model and designing a drill hole arrangement mode are included; 2, interwell tracer tests are conducted on a test unit and a production unit, wherein the steps of selecting a tracer agent, calculating feeding quantity of the tracer agent, feeding and sampling the tracer agent, conducting concentration analysis on the tracer agent, analyzing tracer agent test data and simulating numerical values are included. According to the monitoring method, an interwell tracer method is introduced to the leaching uranium mining process, a numerical value simulation technology is utilized, estimation, monitoring and predicting of the flow direction, the flow rate and the leaching range of a leaching solution are achieved through numerical value simulation of the flow direction, the flow rate and the diffusion range of a groundwater flow field and the tracer agent, accordingly in-situ leaching tests and drill hole arrangement in production are guided, consumption of raw materials is greatly lowered, production cost is saved, and dispersal of pollution to in-situ leaching mine is controlled.