The invention provides an aslant intake manifold orifice milling locating device which is characterized by comprising a bottom plate (1), an inclined plate (2), a flat plate (3), first angle iron (4), a first press plate (5), a first press plate screw (6), a second press plate (7), a third press plate (8), a first compressing screw rod (9), a compression nut (10) and a first support rod (11), wherein the triangular inclined plate (2) is vertically arranged on the bottom plate (1), the inclined plate (2) is provided with the flat plate (3), and the flat plate is provided with the first angle iron (4). The aslant intake manifold orifice milling locating device adopts a plane and pinhole locating mode, an orifice elastic-adjustable locating pin is adopted for locating, so that the position requirement of a product is ensured, an uneven wall thickness condition possibly caused by orifice processing due to blank deformation and orifice size unstability is solved, mounting requirements can be met, and reliable quality and batch production capability can be ensured.