The invention relates to a cleaning coating machine and a cleaning coating method. The cleaning coating machine and the cleaning coating method mainly solves the problem that the surface of a unit tobe plated after plasma cleaning is low in dyne value in the prior art. The cleaning coating machine comprises a powder gasification furnace, a high temperature pyrolysis furnace, a processing chamber,a cold trap, a vacuum pump, a plasma cleaning assembly, gas tank groups and a central controller, wherein each gas tank group is composed of a gas tank and a gas valve, the gas tanks communicate withthe processing chamber through the gas valves, and the central controller is connected with the powder gasification furnace, the high temperature pyrolysis furnace, a powder valve, a rotatable bracket assembly, the cold trap, the vacuum pump and the plasma cleaning assembly. The plasma cleaning assembly comprises a plasma controller, a plasma positive plate and a plasma negative plate, wherein the plasma positive plate and the plasma negative plate are arranged on both sides of the rotatable bracket assembly. The plasma controller is connected with the central controller, the plasma positiveplate, the plasma negative plate and the gas valve. The cleaning coating machine and the cleaning coating method well solve the problems and can be applied to the industrial production of parylene coating.