The invention discloses a traditional Chinese medicine formula for dissolving thrombus, promoting blood circulation to remove blood stasis and clearing and activating channels and collaterals, and relates to the technical field of traditional Chinese medicines. The formula is prepared from saffron crocus, dragon's blood, pseudo-ginseng, radix astragali, salvia miltiorrhiza, herba menthae, borneol,angelica sinensis, musk, peach kernel, hirudin, earthworm protein, radix angelicae, clove, ligusticum wallichii, fructus hippophae and cordyceps sinensis. According to the traditional Chinese medicine formula for dissolving thrombus, promoting blood circulation to remove blood stasis and clearing and activating the channels and collaterals, saffron crocus, dragon's blood, pseudo-ginseng, radix astragali, salviae miltiorrhizae, herba menthae, borneol, angelica sinensis, musk, peach kernel, hirudin, earthworm protein, radix angelicae, clove, ligusticum wallichii, fructus hippophae and cordycepssinensis are selected and put into pure grain liquor to be brewed into liquid medicine; and then the liquid medicine is sprayed to sublingual part or surface of related focus in liquid spraying manner, and the traditional Chinese medicine formula can achieve the effects of promoting blood circulation to remove blood stasis, clearing and activating the channels and collaterals without skin breakage, bleeding and pain, takes effect quickly, has comprehensive effects, is prepared from pure traditional Chinese medicines, is simple to operate and can greatly reduce the pain of patients.