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162results about How to "Prevent indigestion" patented technology

Positively charged water-soluble prodrugs of aspirin

InactiveCN101484415AFast in vivo penetrationAvoid side effectsSenses disorderNervous disorderSolubilityDisease
The novel positively charged prodrugs of acetylsalicylic acid and its analogues in the general formula(1) 'Structure 1' were designed and synthesized. The compounds of the general formula(1) 'Structure 1' indicated above can be prepared from functional derivatives of ASA or its analogues,(for example acid halides or mixed anhydrides), by reaction with suitable alcohols, thiols, or amines. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs, but also bonds to the negative charge on the phosphate head group of membranes and push the pro-drug into the cytosol. The experiment results suggest that the pro-drug, diethylaminoethyl acetylsalicylate.AcOH, diffuses through human skin -400 times faster than acetylsalicylic acid itself and -100 times faster than ethyl acetylsalicylate. In plasma, 80% of these pro-drugs can change back to the drug in a few minutes. The pro-drugs can be used medicinally in treating any aspirin-treatable conditions in humans or animals and be administered not only orally, but also transdermally for any kind of medical treatments and avoid most of the side effects of aspirin, most notably GI disturbances such as dyspepsia, gastroduodenal bleeding, gastric ulcerations, and gastritis. Controlled transdermal administration systems of the prodrug enable the aspirin in the blood to reach constantly optimal therapeutic blood levels to increase effectiveness and reduce the side effects of aspirin.
Owner:于崇曦 +1

Positively charged water-soluble prodrugs of aspirin

InactiveCN101484415BFast in vivo penetrationAvoid side effectsSenses disorderNervous disorderDiethylaminoethyl acetylsalicylateAspirin
The novel positively charged prodrugs of acetylsalicylic acid and its analogues in the general formula(1) 'Structure 1' were designed and synthesized. The compounds of the general formula(1) 'Structure 1' indicated above can be prepared from functional derivatives of ASA or its analogues,(for example acid halides or mixed anhydrides), by reaction with suitable alcohols, thiols, or amines. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs, but also bonds to the negative charge on the phosphate head group of membranes and push the pro-drug into the cytosol. The experiment results suggest that the pro-drug, diethylaminoethyl acetylsalicylate. AcOH, diffuses through human skin -400 times faster than acetylsalicylic acid itself and ˆ¼100 times faster than ethyl acetylsalicylate. In plasma, 80% of these pro-drugs can change back to the drug in a few minutes. The pro-drugs can be used medicinally in treating any aspirin-treatable conditions in humans or animals and be administered not only orally, but also transdermally for any kind of medical treatments and avoid most of the side effects of aspirin, most notably GI disturbances such as dyspepsia, gastroduodenal bleeding, gastric ulcerations, and gastritis. Controlled transdermal administration systems of the prodrug enables the aspirin to reach constantly optimal therapeutic blood levels to increase effectiveness and reduce the side effects of aspirin.
Owner:于崇曦 +1

Positively charged water-soluble prodrugs of ibuprofen with very fast skin penetration rate

The novel positively charged pro-drugs of ibuprofen in the general formula (I) ''Structure 1'' were designed and synthesized. The compounds of the general formula (I) ''Structure 1'' indicated above can be prepared from functional derivatives of ibuprofen, (for example acid halides or mixed anhydrides), by reaction with suitable alcohols, thiols, or amines. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs, but also bonds to the negative charge on the phosphate head group of membranes and pushes the pro-drug into the cytosol. The experiment results suggest that the pro-drug, diethylaminoethyl 2-(p-isobutylphenyl) propionate.AcOH, diffuses through human skin -250 times faster than ibuprofen itself and -125 times faster than ethyl 2-(p-isobutylphenyl) propionate. In plasma, more than 90% of these pro-drugs can change back to the drug in a few minutes. The prodrugs can be used medicinally in treating any ibuprofen-treatable conditions in humans or animals and be administered not only orally, but also transdermally for any kind of medical treatments and avoid most of the side effects of ibuprofen, most notably GI disturbances such as dyspepsia, gastroduodenal bleeding, gastric ulcerations, and gastritis. Controlled transdermal administration systems of the prodrug enable the ibuprofen to reach constantly optimal therapeutic blood levels to increase effectiveness and reduce the side effects of ibuprofen.
Owner:江苏昕晨泰飞尔医药科技有限公司

Feed for promoting skeleton growth of black pigs and preparation method of feed

The invention discloses a feed for promoting skeleton growth of black pigs and a preparation method of the feed. The feed is prepared from the following raw materials in parts by weight: 240-260 parts of rice, 120-140 parts of duck wheat, 50-70 parts of sweet potato residues, 180-190 parts of extruded soybeans, 150-180 parts of maize meal, 70-80 parts of goat liver powder, 80-90 parts of hoof and horn meal, 70-80 parts of ryegrass, 60-70 parts of alfalfa, 30-40 parts of pineapple peel, 20-30 parts of bagasse, 30-40 parts of garlic leaves, 10-20 parts of pomegranate flowers, 20-30 parts of vegetable juice, 2-3 parts of brown sugar, 10-15 parts of fresh milk, 8-9 parts of walnuts, 7-8 parts of fructus amomi, 10-15 parts of freeze-dried pumpkin powder, 10-15 parts of fishbone meal, 8-10 parts of shell powder and 2-3 parts of black pig nutrients. The feed is fine in production, safe, rich in nutrition and crisp in taste; the skeleton growth of black pigs can be promoted; the skeletons of the black pigs fed by the feed are hard and are rich in elasticity and toughness; the growth and fattening of the black pigs are accelerated; the pig body hair color and the quality of pork can be improved; the immunity of the black pigs and the utilization rate of the feed are improved.
Owner:铜陵绿生牧业有限责任公司

1% meat duck pre-mixture

The invention discloses a 1% meat duck pre-mixture, and relates to the technical field of animal feed. The 1% meat duck pre-mixture comprises the following raw materials in parts by weight: 10 parts of meat duck multi-vitamin,1.5 part of copper sulfate, 12.5 parts of ferrous sulfate, 5 parts of zinc oxide, 17.5 parts of manganese sulfate, 4.5 parts of potassium iodide, 2.3 parts of sodium selenite, 60 parts of choline chloride, 13.5 parts of bacitracin zinc, 3.5 parts of Kangdafei, 5 parts of phytase, 247 parts of zeolite, 123 parts of mixture of rice chaff and husk, 5 parts of bacillus, 15 parts of garlic powder, 20 parts of tenebrio molitor dry powder, 15 parts of mussel powder, 20 parts of peanut shell powder, 10 parts of oilseed rape dry powder, 15 parts of asparagus lettuce leaf dry powder, 10 parts of puffing bean cake, 10 parts of rapeseed oil residue cake, 15 parts of sesame oil residue cake, and 6 parts of a traditional Chinese medicine additive. Compared with the traditional feed, the 1% meat duck pre-mixture contains traditional Chinese medicine components, and the traditional Chinese medicine additive cooperates with feed carriers to have effects, so that the normal nutrition requirement of meat ducks can be guaranteed, diseases can be prevented and cured, the immunity of meat ducks is improved, the growth of meat ducks is promoted, toxic and side effects are avoided, drug resistance and environment pollution are avoided, the immunity of human body is enhanced, and the pre-mixture can take effect quickly and is low in price.
Owner:安徽诺阳禽业有限公司

Meat duck premix feed having use ratio of 5%

The invention discloses a meat duck premix feed having a use ratio of 5% and relates to the technical field of animal feed. The meat duck premix feed is prepared from 2 parts by weight of meat duck multi-vitamin, 0.3 parts by weight of copper sulphate, 2.5 parts by weight of ferrous sulphate, 1 part by weight of zinc oxide, 3.5 parts by weight of manganese sulfate, 0.9 parts by weight of potassium iodide, 0.46 parts by weight of sodium selenite, 12 parts by weight of choline chloride, 2.7 parts by weight of zinc bacitracin, 0.7 parts by weight of Kangdafei, 1 part by weight of phytase, 10 parts by weight of methionine, 0.5 parts by weight of an anti-oxidant, 5 parts by weight of lysine, 170 parts by weight of calcium hydrogen phosphate, 25 parts by weight of table salt, 120 parts by weight of stone flour, 79.4 parts by weight of zeolite, 39.6 parts by weight of a mixture of rice chaff and husk, 5 parts by weight of bacilli, 15 parts by weight of garlic powder, 20 parts by weight of dry tenebrio molitor powder, 15 parts by weight of freshwater mussel powder, 20 parts by weight of peanut shell powder, 10 parts by weight of dry green rape powder, 15 parts by weight of dry asparagus lettuce leaf powder, 10 parts by weight of puffed bean cake, 10 parts by weight of rapeseed oil residue cake, 15 parts by weight of sesame oil residue cake and 6 parts by weight of a traditional Chinese medicine additive. The meat duck premix feed contains the traditional Chinese medicine components, can treat and prevent diseases, can improve meat duck immunity, can promote meat duck growth, has no toxic or side effect, does not produce drug resistance and can improve body immunity.
Owner:安徽诺阳禽业有限公司

1% egg-laying duck pre-mixture

The invention discloses a 1% egg-laying duck pre-mixture, and relates to the technical field of animal feed. The 1% egg-laying duck pre-mixture comprises the following raw materials in parts by weight: 4 parts of egg-laying duck multi-vitamin, 2 parts of copper sulfate, 12 parts of ferrous sulfate, 4 parts of zinc oxide, 18 parts of manganese sulfate, 3 parts of potassium iodide, 1.6 parts of sodium selenite, 25 parts of choline chloride, 10 parts of bacitracin zinc, 40 parts of methionine, 25 parts of lysine, 5 parts of egg-laying duck complex enzyme, 12.5 parts of glycine betaine, 2 parts of phytase, 222 parts of zeolite, 110 parts of mixture of rice chaff and husk, 5 parts of bacillus, 15 parts of garlic powder, 20 parts of tenebrio molitor dry powder, 15 parts of mussel powder, 20 parts of peanut shell powder, 10 parts of oilseed rape dry powder, 15 parts of asparagus lettuce leaf dry powder, 10 parts of puffing bean cake, 10 parts of rapeseed oil residue cake, 15 parts of sesame oil residue cake, and 6 parts of a traditional Chinese medicine additive. Compared with the traditional feed, the 1% egg-laying duck pre-mixture contains traditional Chinese medicine components, and the traditional Chinese medicine additive cooperates with feed carriers to have effects, so that the normal nutrition requirement of egg-laying ducks can be guaranteed, diseases can be prevented and cured, the immunity of egg-laying ducks is improved, the growth of egg-laying ducks is promoted, toxic and side effects are avoided, drug resistance and environment pollution are avoided, the immunity of human body is enhanced, and the pre-mixture can take effect quickly and is low in price.
Owner:安徽诺阳禽业有限公司

Poria cocos and gastrodiae rhizoma noodle

The invention discloses a poria cocos and gastrodiae rhizoma noodle, which is prepared from the following raw materials in parts by mass: 100 to 120 parts of flour, 20 to 25 parts of buckwheat powder, 20 to 30 parts of poria cocos, 10 to 20 parts of pumpkin, 10 to 15 parts of rhizoma gastrodiae, 10 to 15 parts of fructus crataegi, 10 to 15 parts of lotus nut, 10 to 15 parts of folium mori, 8 to 10 radix parts of puerariae lobatae, 8 to 10 parts of radix saposhnikoviae, 1 to 3 parts of radix et rhizoma notoginseng and 0.5 to 2 parts of yeast powder. The poria cocos and gastrodiae rhizoma noodle is prepared by the following steps: impregnating, drying and crushing the poria cocos and the radix et rhizoma notoginseng, simultaneously mashing the pumpkin, mixing the rhizoma gastrodiae, the fructus crataegi, the lotus nut, the folium mori, the radix puerariae lobatae and the radix saposhnikoviae, performing solid-liquid separation respectively, mixing two decoction solutions, performing filtering and concentration to obtain clear paste, then mixing the flour, the buckwheat powder, the poria powder, the radix et rhizoma notoginseng powder and the yeast powder, adding water for dough kneading, adding an equal amount of clear paste and mashed pumpkin for three times in a dough kneading process, performing standing for fermentation after dough kneading is finished, and performing forming to obtain finished product noodles by virtue of a noodle maker. The poria cocos and rhizoma gastrodiae noodle is health food, tastes great, and has the effects of effectively keeping fit and enhancing the immunity of the organism, and the effects are better after long-term use.
Owner:刘杰

Blood-enriching Sagittaria sagittifolia L.-apricot kernel paste

The invention discloses blood-enriching Sagittaria sagittifolia L.-apricot kernel paste. The blood-enriching Sagittaria sagittifolia L.-apricot kernel paste is prepared from 18-20 parts by weight of butter, 4-6 parts by weight of white sugar, 1-2 parts by weight of russule, 2-4 parts by weight of Sagittaria sagittifolia L., 1-2 parts by weight of pholiota nameko, 10-20 parts by weight of pine kernel, 188-200 parts by weight of apricot kernel, 50-80 parts by weight of thick broad-bean sauce, 5-10 parts by weight of soybean oil, 1-2 parts by weight of table salt, 0.6-1 part by weight of monosodium glutamate, 1-2 parts by weight of table vinegar, 2-4 parts by weight of yellow rice wine, 4-5 parts by weight of chive, 2-4 parts by weight of ginger, 1-2 parts by weight of gynura bicolor, 1-2 parts by weight of edible amaranth, 14-28 parts by weight of beef, 3-5 parts by weight of pork liver, 1-2 parts by weight of ficus carica, 3-6 parts by weight of pig trotter, 1-2 parts by weight of ginkgo, 1-2 parts by weight of barbary wolfberry fruit, 1-2 parts by weight of black fungus, 1-2 parts by weight of sea cucumber, 1-2 parts by weight of sea-tangle and 3-5 parts by weight of blood-enriching fruit and vegetable powder. The raw materials such as russule and gynura bicolor have the good effect of enriching blood. Sagittaria sagittifolia L. has a delicious taste. Therefore, the blood-enriching Sagittaria sagittifolia L.-apricot kernel paste is excellent and has a fragrance striking the nose.
Owner:HEFEI JINXIANGWEI IND & TRADE

5% Young laying hen premix

The invention discloses a 5% young laying hen premix, and relates to the technical field of animal feeds. The premix is prepared by using the following raw materials, by weight, 2 parts of laying hen multivitamins, 0.25 parts of copper sulfate, 1.9 parts of ferrous sulfate, 0.6 parts of zinc oxide, 2 parts of manganese sulfate, 0.65 parts of potassium iodide, 0.3 parts of sodium selenite, 6.5 parts of choline chloride, 1 part of zinc bacitracin, 1.5 parts of betaine, 1 part of phytase, 90 parts of calcium phosphate, 125 parts of stone flour, 27 parts of salt, 5 parts of methionine, 3 parts of lysine, 0.5 parts of an antioxidant, 153 parts of zeolite, 79 parts of mixture of rice chaff and husk, 5 parts of bacillus, 15 parts of garlic powder, 20 parts of dry powder of yellow mealworm, 15 parts of freshwater mussel powder, 20 parts of peanut shell powder, 10 parts of dry powder of rape plants, 15 parts of dry powder of asparagus lettuce leaves, 10 parts of puffed soybean cakes, 10 parts of rapeseed oil residue cakes, 15 parts of sesame oil residue cakes and 6 parts of traditional Chinese medicinal additives. The premix containing traditional Chinese medicinal components can prevent and cure diseases, improves the immunity of laying hens, also can promote the growth of the laying hens, and has the advantages of increase of the body resistance, rapid action and low price.
Owner:安徽诺阳禽业有限公司

Multifunctional water supplement aqueous solution for livestock and poultry and preparation method thereof

The present invention relates to a multifunctional water supplement aqueous solution for livestock and poultry and a preparation method thereof. The water supplement aqueous solution comprises the following raw materials in parts by weight: 20-25 parts of anhydrous glucose, 10-15 parts of lactic acid, 10-20 parts of citric acid, 2-4 parts of potassium chloride, 3-5 parts of sodium chloride and 40-70 parts of water; the used measurement standard for each component is based on the anhydrous glucose as food grade, lactic acid purity is larger than or equal to 95%, citric acid purity is larger than or equal to 99%, potassium chloride purity is 98.5% and sodium chloride purity is 99.5%; and use amounts of the lactic acid and citric acid enable a pH value of the water supplement aqueous solutionto be 2.8-3.5. The preparation method is as follows: 1) according to the component ratios, the glucose, lactic acid, citric acid, potassium chloride, sodium chloride and water are weighed; 2) firstly, the glucose, citric acid and 70% water are mixed evenly; and then the potassium chloride and sodium chloride are added for mixing; and 3) after the raw materials are mixed, then 30% of the remainingwater is added; then steam heating is conducted to 50-70 DEG C; stirring is conducted for 20-30 minutes; then the lactic acid is added; then the stirring is conducted for 5-10 minutes; and the preparation is completed. The multifunctional water supplement aqueous solution can significantly improve survival rate and breeding efficiency of the livestock and poultry.
Owner:张继成

Health-care heat-clearing noodle and preparation method thereof

The invention discloses a health-care heat-clearing noodle. The health-care heat-clearing noodle is prepared from the following raw materials in parts by weight: 60-70 parts of wheat, 40-50 parts of mung beans, 30-40 parts of millets, 2-3 parts of Ris confusa Seuluy, 1-2 parts of rootlets of Angelica sinensis, 1-2 parts of Radix Cudramiae, 1-2 parts of eupatorium, 20-25 parts of Chinese tumion seeds, 18-24 parts of mung bean sprouts, 20-26 parts of red cabbage, 22-28 parts of flammulina velutipes, 20-30 parts of soybean milk, 20-25 parts of pork liver, 1-2 parts of food improving agents and an appropriate amount of water. The noodle adopts wheat, mung beans and millets as main raw materials, wherein the mung beans have the effects of clearing heat, resolving hundreds of toxins, removing dampness, detoxicating, protecting liver, alleviating water retention, preventing dyspepsia and sore in mouth, preventing regurgitation and vomiting and nourishing yin and blood; the Chinese tumion seeds have the effects of moistening skin, delaying senescence, eliminating malnutritional stagnation, moistening lung, lubricating intestines, preventing phlegm and stopping coughing and killing insects; and the mung bean sprout has the efficacies of clearing away heat and toxic materials, increasing urine and dehumidifying; and the flammulina velutipes has the efficacies of tonifying liver, benefiting intestines and stomach and resisting cancer.
Owner:ANHUI BOTAO GRAIN & OIL DEV
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