The invention discloses a preparation process of a compound honeysuckle film-coated tablet. The method comprises the following steps: heating and extracting honeysuckle, and collecting honeysuckle filtrate, adding forsythia suspensa and scutellaria baicalensis into an extraction tank, adding water, decocting, filtering, combining filtrates, and mixing with the honeysuckle filtrate, concentrating to obtain an extract, and drying to obtain dry paste powder, adding starch, soybean gum, konjac glucomannan and phlorizin into the dry extract powder, uniformly mixing, uniformly mixing with magnesiumstearate, and tabletting to obtain the compound lonicerae flos tablets. Adding sodium carboxymethyl cellulose, polyethylene glycol, polyvinyl alcohol, beta-cyclodextrin, a plasticizer and a coloring agent into a high-speed dispersion machine to prepare a coating solution, and placing the plain tablets and the coating solution in a coating machine for spraying and coating, and drying to obtain thecompound honeysuckle film coated tablets. The compound honeysuckle flower film-coated tablet prepared by the invention has the advantages of moisture resistance, light shielding, taste masking, low water absorption and the like, is not easy to generate cracks, spots and mildew spots, improves the stability of the medicine, and prolongs the storage period, the processing fluidity is good and the production efficiency is improved.