32 results about "Benzylamine hydrochloride" patented technology

This invention discloses a method for reducing the nitrabenzylamine compound to be nitrabenzylamine hydrochlorate whichreduces the nitrabenzylamine compound under hydrogen gas atmosphere by catalytic hydrogenation, using Pd-C / HCl catalytic system. This invention reduces the reaction activity of Pd-C catalyst by adding HCl or hydrochloric acid or CHCl3 which can produce HCl during the reaction to the reaction system, to entitle the Pd-C catalyst with the activity of catalyzing the nitro group of hydrogenated nitrobenzylamine compound to be amidol, without benzyl hydrogenolysis. This invention is characterized of simple operation, mild reaction condition, convenient treatment of post-production material, and broad application future.

The invention relates to a gastroendoscope cleaning product and in particular relates to a rectoscope washing agent. The rectoscope washing agent comprises the following raw materials: water, 2-hydracrylic acid, methacrolein, (2-hydroxyethyl)diisopropyl methylammonium bromide xanthene-9-carboxylic ester, 2,3,4,5,6-pentahydroxy-2-hexenoic acid-4-lactone, cetyl trimethyl ammonium bromide, bicyclo[2.2.1]heptyl-5-allyl-2-carbonitrile, N-(1-methyl-2-phenoxyethyl)-N-(2-chloroethyl)benzylamine hydrochloride, 3-[4,5-dihydro-1H-imidazole-2-ylmethyl-(4-methylphenyl)amino]phenol. The washing agent has a good and remarkable dirt removal effect, especially has a relatively good sterilizing effect while removing dirt generated in a rectal examination process and especially has a remarkable removal effect on three types of bacteria existent in rectums, so that the cleanness and the safety of a rectoscope are ensured on aspects of dirt removal and sterilization.

The present invention relates to a novel polymorphic form of N-[2-(6-fluoro-1H-indol-3-yl)ethyl]-3-(2,2,3,3-tetrafluoropropoxy)benzylamine hydrochloride.

The invention provides a preparation method of an Avanafil intermediate. The preparation method comprises the following steps: dissolving 4-hydroxy-2-methylthio-ethyl 5-pyrimidinecarboxylate and potassium carbonate in DMF to obtain a mixed solution, adding methanesulfonyl chloride into the mixed solution under the stirring condition, continuously stirring after addition until a reaction is ended, adding water and ethyl acetate into a reaction solution, carrying out extraction and liquid separation, carrying out vacuum concentration on an organic phase to prepare 4-methanesulfonic sulfonic ester-2-methylthio-ethyl 5-pyrimidinecarboxylate; dissolving the obtained 4-methanesulfonic sulfonic ester-2-methylthio-ethyl 5-pyrimidinecarboxylate into DMF, adding a (3-chloro-4-methoxy)Benzylamine hydrochloride to obtain mixed liquor, adding triethylamine into the mixed liquor under the stirring condition, continuously stirring after addition until a reaction is ended, adding water and ethyl acetate, carrying out extraction and liquid separation, carrying out vacuum concentration on an organic phase, and recrystallizing to prepare 4-(3-chloro-4-methoxybenzylamino)-5- ethyloxycarbonyl-2-methylthiopyrimidine. The invention has advantages of less environmental pollution, high product yield, safe post-processing and simple operation.